IMURAN Reviews (AZATHIOPRINE)

Average Rating: 2.9 (526 Ratings)

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 IMMUNOMODULATORS ANTIMETABOLITES

 Type: Rx Drug

  

IMURAN  (AZATHIOPRINE):  Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis. In this condition, the body's defense system (immune system) attacks healthy joints. Azathioprine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new kidney as if it were your own (in the case of an organ transplant) or to prevent further damage to your joints (in the case of rheumatoid arthritis). Talk to your doctor about the risks and benefits of azathioprine, especially when used in children and young adults.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR IMURANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Dr. said Skin growths on face, acne, decreased ability to heal. M 18 6 months
100 1X day
5/15/2010
 1  UC No positive effect, skin tags, odd skin problems The skin problems are from Imuran and prednisone, not UC. I had UC long before taking these drugs and never had these problems. I take them and suddenly my skin starts doing weird things. I would never take these drugs again. M 28
1X day
4/30/2010
 1  Crohn's Thin hair, rashes, breakout of warts, infections, looked very sick. M 26 2 years
50 1X day
4/25/2010
 4  autoimmune disease the only side effect is my hair has gotten thin It has helped me so far F 65 17 years
50 -100 1X day
4/24/2010
 1  Ulcerative colitis YELLOW skin and eyes. No energy whatsoever. Hair loss. Acne. My skin is still yellow to this day. M 38 3 months
50 1X day
4/20/2010
 1  UC Severe hair loss, acne, red face, warts, tiredness, vomiting, profuse sweating, depression. CNN did a story the other day about the gene that controls hair loss. The story said that once the hair loss gene is activated, you just keep losing your hair. I think Imuran activates that gene. I was only 18 when I started Imuran and I've been losing my hair ever since. Doctors will try blaming this on UC, but it turns out I was misdiagnosed. I didn't have UC, just food poisoning. M 18 1 years
100 1X day
4/16/2010
 4  Interstitial Pulmonary Fibrosis None. July 2007 start with 100 mg/day. Sept 2009 drop to 50 mg/day. Generic Imuran plus Acetyl Cysteine seems to have arrested my pulmonary fibrosis... which is normally progressive. No side effects. M 62 2 years
100 mg 1X day
4/10/2010
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 1  UC Large bright red rash on face and neck. Was also on prednisone and Cipro. Evidently they can do this, too. Probably taking all three at the same time just makes the side effect worse. Cipro makes you really sensitive to sunlight (I didn't know this; doctor didn't say anything); Imuran makes it so you can't heal, so this has not healed even after 5 years. I'd be really cautious about taking the UC drugs GI doctors hand out so casually. M 19
100 1X day
4/6/2010
 1  Lupus possible Sjogrens Extreme vertigo and imbalance/Constant feelings of edginess and internal tremors, severe insomnia, severe continual low back pain including knees, hands, red face, trunk, arms and diaphoresis(extreme sweating) Foods tasted horrbile/loss of appetite/overwhelming fatigue. Tongue ulceration/frontal headache. An RA doc ordered this along with Prednisone taking it 2x day x 1 wk and to taper the dose in half after 1 wk. My body literally "locked up" with intense cramping and muscle pain when tapering but not sure if it was due to also cutting the Prednisone. Oredered back up to original dose and within 6 days all stated side effects came back with a vengence. I took myself off and self medicated with Benydrl and epinephrine injection due to having a red face, dizziness and body redness that appeared on my face trunk and arms. Felt like I was "Checking out of this universe"...scary...stopped the med altogether but continue to take the Prednisone. Continued to take the antihistamine for the next 3 days. F 65 2 weeks
50 2X day
4/5/2010
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 1  My dog for auto immune anemia My dog's blood vessels had HUGE holes in them and starting leaking and to the point where her lungs filled with water and had water on the brain. As soon as the vets removed the water from her lungs, they filled up again. She died, was ressusitated, went into a coma and died. TAKE THIS DRUG OFF THE MARKET. MY DOG WAS "ONLY" 6 YEARS OLD, WITH AUTO IMMUNE ANEMIA WHICH WAS REVERSIBLE--THE VETS HAD OTHER CASES WITH TOTAL REMISSION. NOT SAFE FOR ANIMALS OR HUMANS, IN MY OPINION AND MY OPINION IS THAT I LOST MY BELOVED DOG TO IMURAN. STOP KILLING OUR PETS AND POSSIBLY OUR SOCIETY. F 55 3 days
30mg 1X O
4/3/2010
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 5  autoimmune hepatitus Low hct only recently. Taking iron supplement which has raised hct. Also have decreased size of the red blood cells. Have also been easily brusing, all of which goes along with the low hct. Will be on a iron supplement regimen. Also have joint pain in hips, knees and ankles. I literally couldn't live without it. If I go off it for more than three weeks, my liver function is terrible. Imuran brings it to the normal range. After 39 years of being on Imuran, if a low hct, that can be treated, is the worst side effect I have, I will take that over how awful I feel when I don't take the imuran. F 56 39 years
35mg 1X day
3/29/2010
 2  Crones Did blood check as required thank god! liver count through the roof, had to get off immediatly or lose my liver. M 50 20 days
1X day
3/23/2010
 1  Blood Issues, Hemogloban count low PML - Progressive multifocal leukoencephalopathy - if you are on Imuran look PML up so you know what to look for and stop immediatly if you get any PML symptoms if you want to save your life. First took Predizone for 9 months once condition was under control switched to Imuran to keep blood issue under control. What a mistake GOT PML now. F 51 6 months
1X day
3/23/2010
 1  UCTD I started having muscle and joint pain after about 1 1/2 weeks on imuran. It got worse. Last night I had very severe muscle pain in my legs, my back is very painful, and my joints hurt. I felt OK on it for a week or so, but now feel much worse than I did when I started. I couldn't work up to the 100MG my doctor wanted. I have been on every other day prednisone therapy for a couple of years, and my doctor wants to get me off of it. I have tapered the prednisone down from 20MG every other day to 11MG. I can't imagine that prenisone at this level is worse for me than imuran. I have a call in for my doctor today, I have stopped the imuran and won't start it again. F 67 2 weeks
25MG 2X day
3/23/2010
 4  Dermatomyositis Severe hair loss, extreme fatigue, lethargy, depression, feeling worthless, joint pain, rash on legs and severe itch, low WBC count Have been on Imuran for 6 months. Worked very well for the disease but having troubles with side effects. Doc is adjusting dose. Taking 5 mg prednisone as well. Hope will be in remission soon! F 30 6 months
50 MG 1X day
3/22/2010
 1  UC My doctor Bushra Sulieman prescribed me Imuran, told me it was safe, etc. When I found out on my own about its risks of skin cancer, he lied to me, said that it wasn't a side effect. Well, I ended up getting skin growths on my face, now I have a really messed up, scarred face--a high dose of prednisone, unmonitored since he didn't know what he doing, didn't help either....Someone might act like this is superficial, to care about having a scarred face, but I guarantee you'd think differently if it happened to you. To anyone who has had a bad experience with this shrug: you should rate the doctor who prescribed it to you on a site like ratemds.com, vitals.com, or drscore.com, if the doctor did not warn you about side effects: that's their job. They really should be fired, if not sued, if they don't do this. Unfortunately that rarely happens. F 18 1 years
100 1X day
3/15/2010
 1  Crohn's disease Two hours after taking this medication I had severe, unrelenting, constant abdominal pain with inability to tolerate anything by mouth other than water the entire time on this medication. Doctor said it was "just the disease" and to keep taking it, even though I told him I was never this bad before. Stopped taking it on Day 5 and went to the E.R. Had to get I.V. electrolytes and Dilauded! I'll NEVER take this again. Was on 20 mg of Prednisone which I'm still taking, and now Vicodin for pain until I see a new gastroenterologist. I'm feeling great. F 22 4 days
50 mg 1X day
3/13/2010
 1  Ulcerative Colitis Dark urine led me to the doc who ordered liver enzymes tested. GGT normal range is 12-43. Mine was 1099. Similar results with AST and ALT. All liver enzymes were normal before starting Imuran. My specialist ordered liver tests every 6 months and claimed that my side effects did not show toxicity. My GP was the one who ordered the tests and took me off Imuran immediately. My advice is to demand more frequent liver tests during the initial stages of taking Imuran. F 65 5 weeks
150mg 1X day
3/10/2010
 1  UC Skin tags, jaundice, infections, red eyes, rashes, muscle and joint pain, weakness and tiredness, Definitely a case of the treatment being worse than the disease. I had my disease under control as best as it would get before taking Imuran. My doctor said I needed to take it, so I took it. Boy was that a mistake. This (or asacol, or one of the other drugs) actually made my UC symptoms worse, and I got bad side effects. My doctor said colitis is why I was tired. Well, I had had colitis before taking Imuran, and never felt this tired. M 20 1.5 years
100 1X day
2/25/2010
 3  Ulcerative Colitis Started with 200mg now down to 100mg - Major hair loss and severe muscle and joint pain, mild depression, skin tags, extreme drop in white blood cell count at higher dosage. Been at 100mg for 3 mos and hair loss has slowed and white blood cell count normal. Muscle and joint pain still severe, no naseau in fact appetite increased and can't seem to lose weight, still developing skin tags, mild water retention, but UC well under control with this med. Don't know which is worse, UC or side effects of this medication. F 53 6 months
100 1X day
2/23/2010

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