PROLIA Reviews (DENOSUMAB)

Average Rating: 1.4 (285 Ratings)

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 Type: Biological Drug

  

PROLIA  (DENOSUMAB):  Denosumab is used to treat bone loss (osteoporosis) in women who are at high risk for bone fracture after menopause. It is also used to treat bone loss in men who are at high risk for bone fracture. Osteoporosis causes bones to become thinner and break more easily. Your chance of developing osteoporosis increases after menopause (in women), as you age, if someone in your family has osteoporosis, or if you take corticosteroid medications (such as prednisone) for long periods. Denosumab is also used to treat bone loss in women who are at high risk for bone fracture while receiving certain treatments for breast cancer. Denosumab is also used to treat bone loss in men who are at high risk of bone fracture while receiving certain treatments for prostate cancer that has not spread to other parts of the body. This medication works by slowing bone loss to help maintain strong bones and reduce the risk of broken bones (fractures). Denosumab belongs to a class of drugs called monoclonal antibodies. It prevents certain cells in the body (osteoclasts) from breaking down bone.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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  Charts & graphs: Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROLIACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Osteoporosis After two weeks of receiving my injection, both hands, fingers and feet toes became inflamed, joints very sore. Fingers locked in a curl position when trying to open the pain unbearable. Effects like trigger fingers as well. To sleep taking anti inflammatory and have resorted to pure emu oil for the pain. Will not have this again. I am not able to work and look after on a daily basis my family and home. F 66 2 months
1X day
5/12/2017
 1  Osteoporosis, Horrible bone pain jaws throbbing muscle ache, I had broken hip and femur bone, 3 years ago from a fall someone tripped me, I just had dental work done this prolia has me in so much pain in all my years nothing like this driving me crazy my bones feel like they are being twisted it's horrible, had I known I would have chosen not to take it, , nurse said it was the weather no way like I said 66 years old I know better, everything changed 6 weeks after the shot This shot is going to finish off my nerves, this needs to be off market, my jaws hurt so bad I can hardly open my mouth, I feel like I am being tortured and not kidding, changed my whole life and I have been through a lot even had 2 children, no more of this for me if I live through this nothing makes the pain go away, like I said horrible, I had 7 therapies on my broke hip and leg I know pain never nothing like this I can't even leave my home I wish I could tell others don't take the chance, irreversible side effects, necrosis.of the jawbone and now I can barely open my mouth, I am terrified, I have a husband not well I was helping him now I don't know what we will do, F 66 0 weeks
5/5/2017
 1  Osteopenia Severe stomach pain went to back, hard time breathing, rash with bumps under & on top of breasts with itching, herd, weight gain, loss of appetite. Got symptoms in a couple of days after shot, Dr said she has never had a patient till now have a reaction. After 2 months symptoms ease up & then right back if not worse. Gave to me cause had two trams breaks & get steroid epidural shots. Would take a break any day than this stuff told her never again. F 63 2 months
60 1X O
5/4/2017
 1  Osteoporosis Bone and hip pain, only a shot...The one and the last!!!Bone into bone un my fémur (radiografía and centellografy detectes), pain un this legal, doctor says It Is nota because of prolia...I'm so sad and temerous! (I'mFrom Argentina) F 55 1 days
60
4/23/2017
 1  osteoparosis None I have been reading reviews about side effects, to determine if I want to use Prolia. It seems that the vast majority of people who use it with little side effect are younger, people in their 40's to early 60's. Older users seem to have the most side effects. I'm not willing to take the chance of negative side effects M 67 0 days
1X day
4/14/2017
 1  Osteoporosis Very severe pain Difficult to walk Balance problem Nausea Painful muscle cramps Awful drug. This was 2nd shot. Never again. I was walking 6miles a day. Now I can't make it around the block F 62 1 months
60mg
4/11/2017
 1  osteoporosis I experienced flu like symptoms accompanied by stomach pains I would rather have osteoporosis than take the drug it really made me feel ill. I mentioned it to my doctor he said it was good for bones but it was making me sick so I decided that was it , from now on I am seeing a great doctor at Stamford Health who is treating my osteo problems in a more natural gentle way , he told me what foods to eat that are healthy and good for bones and also told me I must exercise with a weight vest the osteoporosisvest has made my back etc feel strong and great ! I will never go back to taking the medication it is poison and I hate it. bad bad medication it made me feel so sick I told the MD NO way am I taking that stuff again. people need to read on natural ways to help your body cause this prolia is not the way to help F 63 9 days
30 mg 1X AN
4/10/2017
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 1  Osteoporotic fractures of vertebrae Excruciating spasms, bone and joint pain, esp. shoulders, neck,jaw,thighs. Cough, 10 pound( thus far) weight gain, loss of appetite , constipation I resisted taking anti Osteoporosis drugs, but when I developed fractures, I felt I had no choice. Now I regret it. Having had a congenital leg length difference I thought I knew pain. After having limb lengthening surgery, which was HELL my pain pretty much resolved. This pain is worse then I ever experienced. After all I went through, to be going through this is discouraging. F 69 9 times
30mg
4/5/2017
Email
 1  Osteoperosis Severe abdominal and thoracic back pain and now waking up at night with tingling of mouth and tongue and fingers. I feel it should be banned or Dr's should try it first before prescribing to patients. F 71 2 months
60 mg
4/3/2017
Email
 1  Osteoporosis Immediately flu like symptoms. Total exhaustion. Horrible sores inside my mouth. Upset stomach. Achy all over. Skin issues. Deep bronchial like coughs with yellow spectrum. Infected runny nose. Mental cloudiness. Restless leg at night. Very low energy. Prolia: 2-17-2017: 1st Prolia shot. Next day got severe flu 😷 symptoms that lasted a hard 3 weeks. Lost weight, 6 pounds! I went to my GP's nurse, who said that it was definitely NOT Prolia because my symptoms were wrong, and she put me on HEAVY antibiotics. By the fourth week of my flu like symptoms I thought that I was getting better; but not completely, I still feel to this day very achy and exhausted; and over two months after getting the first shot. I have not had one healthy day yet. 3-29-2017: Asked my spine doctor, who is recommending surgery on my lower lumbard L3, L4, and L5, about Prolia because of its negative effect on me. Would Prolia effect the operation negatively? "No". He said, "and to stay on it because it is good for the spine". 4-2-2017: More and more blisters and canker sores are starting to grow inside my mouth making eating difficult. Now I am rinsing mouth out with salt water. Also, I have an infected running left nostril. I am very very tired. Rough skin spots on chest, arms, forehead. I am coughing a lot, and twice in the past week I coughed up yellow globs. Some stomach issues too. I am sure that all of the above are a reaction to my Prolia shot on February 17, 2017. I am just 2 months into this resulting brain-fog. 4 more months to go. Two doctors and a nurse love Prolia, BUT I HATE IT! Never again. F 70 46 days
60 mg/ml 1X O
4/3/2017
 1  osteo. trouble breathing - rib cage area sensitive. developed a cough. EKG and lung xray done and OK First 2 shots ok but after 3rd symptoms appeared for a couple of months and slowly dissipating. Don't plan to get another shot in June. F 75 3 times
3/28/2017
Email
 1  Osteoporosis Flu like symptoms....nausea, GI problems...exhaustion. Took shot on March 15th and was violently sick the following Saturday....vomiting and wretching.....haven't been well since. Went to my primary and he suggested I see a GI doctor. I asked him if he thought it was prolia but he didn't know about the drug. After reading all these reviews, I am convinced it was the shot. I was perfectly fine before March 15th. Would not recommend. Will not take a second shot. I am concerned about the length of time it will take my body to rid itself of this drug. I missed a week of work already. F 71
1X O
3/25/2017
Email
 1  Osteoporosis Immediate UTI with dark urine and burning. Flu like feeling the first day. Hive on my face and hand. This will be my last. F 58 1 days
1 shot
3/20/2017
 1  bone density Extreme pain ended up in hospital flu symptoms, headaches, fevers, extreme fatigue that keeps me from even getting out of bed, jaw pain, stomach upset, bladder issues, muscle cramping, memory issues, every day is challenge. Took this shot on 2/10/17 WILL NEVER TAKE AGAIN. I cry every day for taking this injection. My quality of life has been drastically changed to the worst from this injection. F 77 1 months
60mg 1X O
3/11/2017
Email
 5  post-menopausal osteoporosis No side effects with the first shot! F 66
1X O
3/5/2017
 1  osteoporosis joints ached, stomach pain, muscle pain, bone pain, groin pain. Took 1 injections and six weeks out side effects are severe. Will never take it again. F 1 months
1 shot 1X O
2/23/2017
 1  ost only took once Dec. 2014 NEVER AGAIN, tired could sleep for 12 hours achy, ears hurt, groin ache. Have been to every MD and test known. As of Oct. 2016 legs and arms ache, heaviness, numbness have gotten so bad, I thought they were blood clots. I will never take again. Along time as passed and i still feel awful, still having tests to figure out. Took 61/2 months of Forteo injections, couldn't walk, finally off and starting to feel better when the 4th MD insisted I take Prolia. F 63 1 months
1X O
2/21/2017
Email
 1  Osteoporosis Extreme joint pain began 2 weeks after shot.Along with complete exhaustion. Flu like symptoms. Five weeks out insomnia. Six week out upper stomach pain with nausea.Tingling in left hand. And the joint bone muscle pain kept getting worse all the time. NEed help getting up from sited position. I am not over weight and exercise 5x a week. This stuff is posion. Will not take again. Going back to primary care tomorrow. F 66 6 months
Shot
2/20/2017
 1  Osteoprosis Severe severe debilitating low back pain. Caused me to not be able to function; bed ridden. Cannot sit in chair, cannot sit up in bed, Constant debilitating pain. Constant debilitating pain. No I cannot walk. from the knee down, my legs will not walk and I have to use a cane or a walker. Are used to work out three times a week. I have strength depletion and constant weakness. I used to be a very active vital person who played with grandchildren and now I am a zombie I am on able to complete grocery shopping trips F 70 2 times
2/19/2017
Email
 1  Osteoporosis 2 weeks after Prolia injection, started coughing and left arm hurting while driving and sleeping. Phoned regular physicians and told I had virus going around. Waited until end of December, went to urgent care and told I had bronchitis, so was given antibiotics and prednisone which cleared up in time for cataract surgeries(they went well). Soon after surgeries, I started coughing again. I still have arm problem. Now I am questioning whether I should get my 2nd dose in May. F 70 3 months
1X day
2/5/2017
Email

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