PROLIA Reviews (DENOSUMAB)

Average Rating: 1.4 (285 Ratings)

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 Type: Biological Drug

  

PROLIA  (DENOSUMAB):  Denosumab is used to treat bone loss (osteoporosis) in women who are at high risk for bone fracture after menopause. It is also used to treat bone loss in men who are at high risk for bone fracture. Osteoporosis causes bones to become thinner and break more easily. Your chance of developing osteoporosis increases after menopause (in women), as you age, if someone in your family has osteoporosis, or if you take corticosteroid medications (such as prednisone) for long periods. Denosumab is also used to treat bone loss in women who are at high risk for bone fracture while receiving certain treatments for breast cancer. Denosumab is also used to treat bone loss in men who are at high risk of bone fracture while receiving certain treatments for prostate cancer that has not spread to other parts of the body. This medication works by slowing bone loss to help maintain strong bones and reduce the risk of broken bones (fractures). Denosumab belongs to a class of drugs called monoclonal antibodies. It prevents certain cells in the body (osteoclasts) from breaking down bone.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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  Charts & graphs: Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROLIACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Osteoporosis Psoriasis on scalp and hair is falling out. Will not be taking a second shot! F 56 1 days
12/19/2015
 1  Osteoporosis Blood pressure was so low I could barely walk. Horrible itching, confusion, it was like having a cloudy brain. Hip and knee pain on the left side which I still have and I quit taking PROLIA a year ago. The stomach pain was awful everyday. It is a horrible drug. I finally figured out it was the PROLIA as I would start to feel good enough to eat about 3 weeks prior to my next injection. None of my Doctors thought it could be the PROLIA they were all wrong. DO NOT TAKE PROLIA. I bet there will be a class action lawsuit suit. My left leg and hip still hurt. F 70 3 years
12/18/2015
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 1  Bone density Extreme back, groin and hip pain. Nausea Barely able to function, need cane, X-rays show disc problem but thigh is most painful. Rheumatologist says not related 68 and never had these issues. Will not take another shot. F 68 45 days
1X O
12/5/2015
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 1  osteopenia I have eczema now, all my bones ,hurt, terrible acid reflux, burning of my esophagus, headaches,insomina, ankles swell,nails pulled away from nail bed When I complained to my gyno she said not from shot call my GP, my GP said he would NEVER have given me Prolia. Also I have heard that if you do not have Osteoporosis you should not be getting this shot. F 63 1 years
2X O
12/4/2015
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 1  osteoporosis after one injection last September, I had no side effects until the beginning of November when I developed pain in my hips, lower back and now my legs and ankles. I thought it was from exercising, but have stopped that and I am in pain just walking. I would like to know how long it will take for these symptoms to be alleviated. I regret taking the first injection, but my physician pressured me because I had a minor fracture last year. I will not take the second one. F 72 100 days
1X O
12/4/2015
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 1  Osteoporosis Took 2nd injection Sept. 2015. After very 1st injection, I started experiencing hip pain. After the 2nd injection, the hip pain (yes, Plural) has grown "so" severe I can "barely" limp. I have not been able to walk normally for at least 2 months. The pain is so dibilitating that I am a mere shell of the person I used to be. I am 62, petite and "was" very active. Now it takes everything I have to endure the pain simply walking to the bathroom in the morning. It has really taken a toll on me and aged me beyond belief. I can't believe that I am now using a cane! To anyone out there who is listening . . . do not take Prolia! When a Class Action Law Suit is brought forth (and there is no doubt in my mind there will be), I can assure you, my name will go on that list. This drug is BAD NEWS! F 62 1 years
2X O
11/29/2015
 1  Osteoporosis Terrible rash. Went to two GPS and two dermatologists and no one can diagnosis correctly. One said it was Staph, one said it my diet, one had no idea, and the last one to me to bathe in bleach water ,apply two different kinds of prescribed lotion after bath g with special soap and then Appling special lotion then add the two different prescriptions she ordered for me. I was to do this for the rest of my life.... Has anyone had anything get rid of the rash? I'm in my sixth month of constant rash, itching and constant deep painful heartburn. I thought I was having a heart attack. All this plus constipation and continual throat infections. F 65 8 months
30mg
11/11/2015
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 1  osteoporosis knee pain flu like symptoms I will not take any more shots of this horrible drug...4 more months before it gets out of my system F 74 2 months
1X O
11/1/2015
 1  Osteoporosis Red swollen itchy face legs and arms. Neck pain. Weight loss, diarrhea . Fatigue depression. It aged me 10 years. It's a killer . I have every side effect possible from this drug. I called the manufacturer and they said how did I know it was the Prolia that caused all my side effects!! I will get an attorney!!! My doctor reported this the the FDA also. F 73
60 2X O
10/31/2015
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 1  osteopenia Arm and shoulder pain. Had the shot in my right arm. I went and had a MRI. It shows I have adhesive capsulitis also called frozen shoulder. If you are given this injection in the arm and it starts to hurt I would recommend a MRI. This drug is horrible. The doctors act like they don't want to hear it. Mine told me there wasn't anything she could do about it and that it would go away. F 54 3 months
60mg 2X O
9/8/2015
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 1  Osteopenia This is my second post about this horrible drug. It will be six month Aug. 23, 2015 since I took my last shot. I am still having the side effects, most of, if not all of the side effects. Not a doctor, but I would not recommend Prolia to anyone for Osteopenia or Osteoperosis! I was very active, but now I feel that the effects of this drug have aged me by at least 10 years!! Still hurting!!! My reason for this second post is to inform others Prolia was originally for " Bone Cancer Patients." I have a friend that has been taking it for bone cancer and she and I were talking and comparing our aches and overall feelings, they were very similar! She gave some advice that her oncologist gave her to help with the horrible side effects! This drug should not be prescribed for Ostepinia or Osteoperosis patients, only for cancer patients!! It makes me wonder about the drug company and the doctors prescribing this, perhaps Money, just saying, and hopefully will be asking my doctor Monday, August 24, 2015, why?? The cost of one injection is $1994.00. Beware of Prolia! F 68 3 years
60 mg 7X O
8/21/2015
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 1  Osteoporosis Agonizing pain in my neck, back, ribs, and my joints are all swollen and painful. Increased migraines, gas and constipation, bladder and urinary pain . It actually hurts to breathe! This was my 2nd injection and I hoped for a different experience, this time. 3 weeks later, I am in agony!! Last time the agony lasted 3 1/2 months. some days I just cried, the pain was so bad. I made a commitment to take Prolia because my osteoporosis is so bad, and my G.I. system can't handle any of the other drugs. I don't know if I can keep that commitment.. I don't know if I would have made the commitment to this treatment, if I knew all of the misery it would be. I have just about every side effect listed, but my doctor and I agreed this is the only drug that will work for my very severe osteoporosis. 1 more year 2 injections to go, before I get to take a, "drug holiday." If I survive that long! F 49 7 months
X 2X O
7/23/2015
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 1  severe osteoporosis No side effects from my 1st injection which was given in my stomach. 2nd injection was given in my arm. A week later I had severe bone pain in my legs, so bad that I laid in bed and cried for weeks. It has been almost a year since my injection and I still experience the debilitating bone pain from time to time. I feel that this medication has poisoned my body.Also experienced urinary retention problems that continue to this day. Worst decision I ever made! I don't know how this drug was ever approved. My doctor highly recommended this medication since I was not able to tolerate other medications for osteoporosis due to side effects. Now I take my calcium supplements and hope for the best. F 54 1 years
10mg
7/14/2015
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 2  Broke 4 bones in my back in 2013 Had my last of 4 shots today, I dont remember feeling this terrible before.I won't be sleeping tonight due to heartburn,back and all over body aches,feel sick to my stomach and exhausted. If I had known all the side affects I would have thought long and hard about the necessity of taking this drug My concern is will this drug ever get out of my system ?? F 73 2 years
Not sure
7/7/2015
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 1  osteopenia Please read this before taking the PROLIA injection. My endocrinologist recommended prolia for me after taking the drug called ACTONEL for 8 months. The Actonel's side effects were killing me, literally... After prolia was approved by my insurance company, the drug was shipped to my doctor. He specifically told me, because I asked, that the side effects from prolia were mild. He said the same thing about Actonel. I called his office today after doing extensive research on this drug and canceled my appointment for the injection. I hate to say it...but I think these doctors are receiving a kick back from the drug companies for having patients taking these horrible drugs. I'm going to continue taking vitamin "D" and calcium supplements and hope for the best. I'm very active and I feel great now after I stopped the actonel. I'll never get talked into a medical trap again.. M 63 0 days
60mg 1X O
6/8/2015
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 2  osteo I have been taking Prolia for 4 years, 2 injections annually. I received last injection in April of 2015 and for the very first time I had many side effects. Itching, nausea,aching, headachs,back pain. I will not be taking the drug again. F 66 4 years
60mg 1X O
6/4/2015
 1  Osteo Very servere bone and joint pain. Can hardly use my hands at all. Rash and itching over most of body. Nausea, tingling and numbness in feet, loss of appetite. Sore throat, headache, Weakness and lethargy. I'm a high energy person or use to be. I hardly ever have joint /bone pain. I took the shot in March 2015 and started having side effects within 2 days. It's been 2 1/2 months and side effects are getting worse.I feel like this drug has poisoned my system. I wish I had read more on the side effects and had found this website before taking this horrid medicine. Doctors need to give their patient literature on it when they recommend it. My first shot and last!!! F 65 1 times
6/1/2015
 1  osteoporosis I got 60mg prolia injection Feb 17, 2015.. I woke up April 16, 2015 with back pain, both arms pain and both knees pain..I called Ambulance and they took me to emergency.. I am still having pain in my right knee and back and arms pain.. it is terrible and I used to run, exercise, take only stairs..now I cannot do any of those things and I am not the same person any more.. terrible pain I would never take another injection even the doctor saying it is not from prolia..but I think it is the side effects from prolia because I have never have pain like that before.. and I was very active M 53 6 months
60mg 1X AN
5/24/2015
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 2  Have Osteoporosus 1st shot no side effects. Had second shot 4 weeks ago and have continuous heartburn and bladder burning, flu symptoms, aches in my joints, pains in my chest, excessive itching of skin, pains in my kidneys. I will not take these shots any longer they are NO better than Reclast Infusion which I was horribly sick on. I will just wing it for the rest of my life taking Calcium and Vitamin D supplements. F 65 1 years
30mg 1X O
5/22/2015
 1  osteoporosis still have terrible side effects after only one injection a year ago - vertigo and balance problems, weakness and fatigue - had to stop working. Worst decision I ever made. F 58 1 days
30 MG 1X AN
5/12/2015

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