PROLIA Reviews (DENOSUMAB)

Average Rating: 1.4 (285 Ratings)

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 Type: Biological Drug

  

PROLIA  (DENOSUMAB):  Denosumab is used to treat bone loss (osteoporosis) in women who are at high risk for bone fracture after menopause. It is also used to treat bone loss in men who are at high risk for bone fracture. Osteoporosis causes bones to become thinner and break more easily. Your chance of developing osteoporosis increases after menopause (in women), as you age, if someone in your family has osteoporosis, or if you take corticosteroid medications (such as prednisone) for long periods. Denosumab is also used to treat bone loss in women who are at high risk for bone fracture while receiving certain treatments for breast cancer. Denosumab is also used to treat bone loss in men who are at high risk of bone fracture while receiving certain treatments for prostate cancer that has not spread to other parts of the body. This medication works by slowing bone loss to help maintain strong bones and reduce the risk of broken bones (fractures). Denosumab belongs to a class of drugs called monoclonal antibodies. It prevents certain cells in the body (osteoclasts) from breaking down bone.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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  Charts & graphs: Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROLIACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Bone scan showed mild osteopenia Severe fatigue. I feel like I am in a daze and cant stay awake . Severe depression and anxiety. Back hip and shoulder blade pain and aching in my chest. I regret ever taking this shot . I am so afraid I will never be well again. 59 5 weeks
Unk
8/7/2016
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 1  osteoporosis Within two days of first shot developed Herpes which I have not had for 20 years. Will not be getting another shot. Now on Valtrex. Hope this problem doesn't continue until the six months of this drug is out of my system! F 69 1 weeks
1X day
7/27/2016
 1  oesteoporosis I had 3 shots without any side effects then on the 4th shot my legs and arms came out in bright red spots and sore arms and shoulders. Will not be continuing with the treatment, especially after reading other peoples concerns. F 65 18 months
4X AN
7/19/2016
 1  Osteopenia Ringing in ears-fatigue, rash, pain in hip and leg. Flu like symptoms after each injection. Will not take any more!! Ringing is debilitating. Just hope it goes away after 6 mths. Took me 3 injections to realize symptoms were from this and getting worse. F 70 18 months
2X O
7/16/2016
 1   1 days
7/10/2016
 1  Osteoperosis After 2nd week, and this has occurred after last 3 shots, get severe back pain, can barely walk or move, low calcium levels, and blood levels. Will not be getting another injection, trying to build my immune system to get this drug out of me. M 75 6 months
2mg
7/9/2016
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 1  bone loss uti hive like rash all over my thighs and torso I will not be taking Prolia again F 73 4 months
60 1X O
7/2/2016
 1  Osteoporosis I took my first and only shot of prolia in November 2015. Since then the pain in my feet and legs has gotten so bad I feel like I'm 10 years older than I was before I had the injection. My husband has noticed a big difference in my gait when I walk. Like an old woman. I won't be getting another injection of this horrible drug. F 64 1 years
60 mg
6/29/2016
 1  Severe osteoporosis Very tired with flu-like symptoms the first three weeks. After that, I developed severe restless leg syndrome, as well as burning in my feet, especially at night. This keeps me awake most nights and I'm exhausted. GP and endocrinologist couldn't give me answers. Will never take it again. F 61 6 months
1X day
6/22/2016
 3  Osteoporosis First time 2/4/2016. First week only metal tast, around 4/15/2016 started To get a itchy rash on legs, arms,back went to dermatologist blood test and drug to help with itch at this time rash is every where except face and feet. Evenings are the worst. At present the itching is erratic comes and goes and at different locations. This is the first time with a skin issue so I am suspecting Prolia M 76 4 months
6/13/2016
 1  Osteopetrosis Strep 2x. Back pain, sciatic nerve, joint pain, fatigue F 4 months
60 mg
6/13/2016
 1  To strengthen my bones after a frac Pain and severe swelling on site of break. Pain in my whole body. Still go through periods of pain in my leg and hips. Back pain can be debilitating. It is now June and I am having another attack of pain that I can attribute to nothing else than being from Prolia. F 60 1 days
Not sure
6/8/2016
Email
 1  Osteoporosis Received 1st injection in March. Side effects started few weeks later with stiff and aching knees, hips, elbows. Now having severe pain, numbness, tingling of my right hand and fingers. Started with stiffness, numbness and tingling in the morning with severe pain in my thumb and would subside by lunch time. Now pain is severe in my entire hand and fingers all day and even wakes me from sleep. Never taking again...I will take a broken bone over suffering like this! F 53 1 times
60 1X O
5/15/2016
 1  Osteoporosis Two months ago: excruciating pain in hip and slightly less pain in lower back; one month ago: sore, achy hands, arms (mostly between shoulder and elbow) and neck/back between shoulders. This is my second post. Thought I was done with side effects after the excruciating hip and back pain in March. Have been dealing with extremely sore/achy hands, arms and neck/upper back for the last month. Started with the area between my right shoulder and elbow, then moved to my left arm and neck/upper back. Can't wait for this drug to disappear out of my body!!! F 57 1.5 years
60mg 2X O
5/12/2016
Email
 1  Early osteoporosis Extreme pain in legs (ankle to top of thigh) and all of arms plus hands. Additional back pain. Got 6-mo. shot about five weeks ago, a sort of tingling started after about 10 days, progressing into severe pain. Age 78 I now know that my side effects are common but did not know in advance. Unable to learn anything about what is going on that causes the pain. Varies in intensity. Prognosis? I don't know. Where is the FDA? Where are our doctors? How can it not be criminal - giving me a drug that causes so much pain as I try to hang onto my life. F 78 5 weeks
60 1X O
5/10/2016
 1  Medication for breast cancer & osteo UTI, bladder infection; constant urinary pain, skin cracking/peeling. Since I am/was also on Armidex, I'm not sure if my joint pain is from that for Prolia. After dealing with these symptoms for months, my own investigation concluded these are all side effects of Prolia. My oncologist agrees. I'm hoping once my January 2016 injection wears off I get back to normal. I will NOT take another Prolia injection. F 65 2 times
60 mg 2X O
5/6/2016
Email
 1  Osteoporosis Aching all over, sinus infection, itching, extreme fatigue, memory problems, depression I've had one shot, 4 months ago, will certainly not have any more. F 68 4 months
1X O
5/5/2016
 3  Osteoporosis Achey at first but Tylenol helped. A little gastrointestinal distress for a few days. F 51 1 weeks
60 1X O
4/30/2016
 1  Osteoporosis Side effects started at two weeks after taking injection and slowly increased for several months. The side effects did not magically go away at six months. I began to feel some relief after 11 months. Example, being able to sleep thru the night one or two nights a month. Has effected every aspect of my life. No help or support from GYN or Endocrinologist. No response from doctors, just blank looks. They didn't know what to do. Find a doctor who will listen. Believe what your body is telling you. Keep a journal of side effects. I hope everyone here has reported to FDA: 1-888-463-6332 Amgen 1-800-772-6436 F 57 6 months
60mg 1X day
4/30/2016
 1  I will not take prolia Teeth becoming loose My father who is 78 has been on Prolia for 18 months and he has always had really good teeth. Within the last 12 months the dentist has removed 3 teeth due to being loose but no decay. My father was not told of any side effects regarding jaw rot and did not mention he was on Prolia to the dentist. Doctors really need to take the time to explain all the side effects, especially to the elderly. I myself was diagnosed with osteoporosis in Jan 2016 as I ended up in hospital with 2 compression fractures in my spine. I was told my T score is -5.6. After researching on the net I decided to keep away from Osteoclast type products like Prolia as long term use can increase the risk of fractures as the bone becomes brittle. I take vitamins D3, K2, magnesium, silica and am on a Osteoblast type medication. The thought of taking Prolia scares me. F 55 18 months
1X O
4/29/2016
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