ALDACTONE Reviews (SPIRONOLACTONE)

Average Rating: 3.1 (155 Ratings)

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ALDACTONE  (SPIRONOLACTONE):  Spironolactone is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems. This medication is also used to treat low potassium levels and conditions in which the body is making too much of a natural chemical (aldosterone). Spironolactone is known as a "water pill" (potassium-sparing diuretic).   FDA Approval Date: 1983-12-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on ALDACTONE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ALDACTONECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  acne and thinning hair WEIGHT GAIN - ABOUT 5 POUNDS ON MY 100 POUND BODY, BREAST ENLARGEMENT (A WHOLE CUP SIZE) BREAST TENDERNESS. FAT REDISTRIBUTION - INCREASED BELLY FAT. This is a terrible drug. It is a powerful testosterone, androgen suppressor. It causes rapid weight gain, fat redistribution and general flabbiness, as well as enlarged painful breasts. In short, it is a disfiguring drug. I don't know anyone who would trade a few zits for a fat, flabby body and enlarged, painful breasts. I experienced these side effects and am in my 70s.This drug is given out like candy by dermatologists who deny its very common and devastating side effects. Thankfully I only took it for 5 weeks (50 mg once a day) and eventually returned to normal. Many women are not so lucky and are permanently damaged by this supposedly benign drug. F 74 5 weeks
50 1X day
2/27/2023
 1  Bilateral primary aldosteronism Bad insomnia, dry itchy skin, hair completely dried out, constant tense/anxious feeling, hot flushes, upset stomach and nauseated feeling for an hour or so after taking, breast growth and increased sensitivity. Beware perimenopausal women, this drug will tip you straight into far more menopausal symptoms, the worst being insomnia. I'm going to try Eplerenone ... it's a lot more expensive ... but doesn't have the hormonal interference of Spironolactone. Spiro blocks progesterone and testosterone receptors and increases cortisol, as well as aldosterone. None of these are conducive to sleep and losing them definitely increases menopausal symptoms unfortunately. It did however work well to lower blood pressure caused by high aldosterone levels produced by malfunctioning adrenal glands. F 49 6 months
25mg 1X day
2/26/2023
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 1  High blood pressure Psychotic spinning, loss of appetite and faint nausea, loss of sexual function. Didn't reduce blood pressure. M 62 14 days
25 1X day
2/4/2023
 1  Acne Chronic headaches, fatigue, irritability, flat mood, anxiety, tingling sensations, tinnitus, overall aches and pains, chest pains, panicky feeling I used to have breakouts in my 30’s , more so than now. My dermatologist put me on this drug to “ calm down my pores”. I just assumed I was high in testosterone since I’m still breaking out at 50, occasionally having a zit or two once a month. I got my total testosterone checked during my first week on this drug, my number was 19! I’m actually low! I don’t have hormonal acne after all and this drug is specifically intended for woman who are. Testosterone is good for our bodies within normal levels ( 15-90). Ladies, get your testosterone tested before going on this pill. If it’s normal, then you’re acne is caused by something else, usually overactive oil glands. Dr’s should suggest or require their female patients get their testosterone levels checked before prescribing this drug off label. It’s no wonder so many people have adverse side effects!!! I’ve been off this drug for a few days and starting to see improvement, slowly. In my opinion and experience, this drug is dangerous and should not be taken lightly for those, including myself who are “ hormonal sensitive “. F 50 2 weeks
25mg
8/28/2022
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 1  BP 10 kgs weight gain, breast enlargement under arms sore and red in both armpits . Skin under arms like flab M 74 9 months
12.5 mg 1X day
4/7/2022
 1  Acne constantly peeing, light-headed, loss of peripheral vision, stomach/intestinal pain After having a terrible experience with this drug that landed me in the ER after taking it for a month, I found out that it is a hormone blocker and blocks testosterone production. This was prescribed by my dermatologist for minor acne around my chin but not once did they ever test for high testosterone to see if that was actually the cause of my acne. I stopped taking it 8 months ago and I am still going to the doctor to try and heal my gut from the damage this drug did to my digestive system. I still have abdominal pain. Do your research before taking this drug! Clearly, the doctors who are prescribing it do not... F 27 30 days
12.5 1X day
12/9/2021
 1  Acne No matter how clean I ate or the amount of exercise I gained 22 lbs in 3 months. I haven't had a period in 3.5 months. All in my stomach, butt, and thighs. Nothing fits me. I've been off for 2 months now and my weight has not gone down. Can anyone give me advice? My Thyroid is functioning properly. Testosterone is low and waiting on my estrogen test to come back. I've never had any of these issues before taking this awful drug F 42 4 months
100 1X day
10/13/2021
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 1  Acne Bloating, weight gain, breast enlargement, fatigue Is wonderful for skin, but not worth the side effects. Was at 50mg to start and there was gradual slight weight gain and I didn't think anything of it. Then dr increased to 150mg and the bloating, breast enlargement and rapid weight gain began.. just thought it was due to COVID lockdown so just started eating cleaner, journaling calories and upping my workouts. After cutting my calories 500-1000/day and working out like crazy(HIIT, cardio and weights) I still gained 15 more lbs in 2 months time. That's when I started researching and saw these same side effects were effecting others. So I stopped it. 1 month in i don't feel like a blowfish, bloating in stomach has gone down and I've lost 5 lbs. I'll continue to workout and see if the rest of the weight falls off, but am seriously upset my dermatologist did not tell me this was a side effect. All she said when I asked her about side effects was that I needed to stay hydrated and may feel a little dizzy if I stand up quickly. After researching the medication side effects myself I see that there are WAY more side effect listed than she let on. Again, upset she didn't tell me up front of all of them- so much that I don't think I'll be back to her. F 43 7 days
50-150mg 1X day
6/15/2021
 1  Edema Lactic acidosis, ovarian cysts, ovarian torsion Within 2-3 months, developed an ovarian cyst that grew large enough to torsion, requiring emergency surgery. Two weeks post-cystectomy, developed severe abdominal pain requiring hospitalization; eventually found to be lactic acidosis. As lactic acidosis was diagnosed (confirmed by labs), a second large cyst had grown on other ovary, requiring cystectomy. At no point did any medical providers suspect spironolactone having any role. Discontinued Spironolactone and second cyst shrunk, disappearing entirely over one month period, and lactic acidosis dissipated. No large ovarian cysts or torsions before or since. Was concurrently taking Metformin ER for PCOS with Spironolactone. F 32 4 months
200 MG
5/26/2021
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 1  renal failure I started with 12 and half mg per day. It made me feel awful. Foggy, drowzy and confused. Eventually I made myself adjust to it but never felt better. Physician increased dosage to 25 mg and I feel worse than ever plus depression because I feel so lethargic. I do not like it nor do I feel any improvement in my symptoms. F 74
25 1X day
8/30/2020
 1  Blood pressure Mood swings. Weight gain. I have gained a substantial amount of weight in stomach, thighs, buttocks, and arms. I have never been this heavy in my life. I am moody and depressed. F 63 2 years
25
7/1/2020
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 1  Edema of legs 20 pound weight gain, tired all the time F 69 1 days
30 mg 1X day
3/19/2020
 1  Hormonal Acne Weight gain Do not take this medication unless you are okay with the possibility of gaining weight!! I gained 25lbs while maintaining my normal diet and exercise habits. I have never weighed this much even before I ate healthy and worked out. F 20 6 months
50 mg
9/29/2019
 1  Acne Weight gain 37 7 months
100
8/22/2019
 1  Hormonal acne Weight gain in my lower abdominal area - did not change my diet or exercise routine, and feeling puffy in my lower stomach which is super depressing for me. So, this in turn caused me to be a little depressed. Somewhat tired too. So sad. Really wanted this to work but saw wayyyy too many reviews on weight gain and I attribute my weight gain (3-5lbs in a month) to the medicine F 33 1 months
25mg
8/15/2019
 1  BP Dizzines, low platelet count affecting immune system, bruising, breast enlargement, belly fat with no weight gain involved Still recovering from side effects. Not for me. F 70 6 months
25 1X day
1/20/2019
 1  Acne Headaches, dizziness, heart palpitations, weight gain This is the worse medication ever. Do not use F 36 90 days
25 MG twic
10/2/2018
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 1  Hormonal acne major weight gain, gaining 7 pounds in one week despite clean diet and exercising 5 days a week. I gained 20 pounds in 2 months and have been off the medication for three months now and the weight will not budge. I am super healthy and work out hardcore and am now the biggest I’ve ever been in my entire life because of spiro. Not matter how hard I work out or how clean I eat, the weight won’t come off. It’s just devastating and depressing! F 35 60 days
100
11/2/2017
Email
 1  Acne Within the two month period of taking this medication,I have gained 15 pounds and I've been experiencing headaches and severe neck tightness for the past two weeks. When I spoke to my Dr a month ago about the weight gain, she told me that it wasn't a side effect and that it should make me lose weight. It has helped with acne, but the side effects arent worth it. I'm switching to another medication asap. F 25 2 months
10/16/2017
 1  Acne Please please please someone tell me how long it takes to lose the weight gained from this medicine. I gained a total of 17lbs with 2 months of taking meds and still another month after stopping it. No matter what I do, how clean my diet is and how much I work out nothing changes. I'm so depressed. Dr said it would fall off once out of my system. Well it's been exactly 2 months now I've been off it. Someone please help. I'm not seeing any answers for how long it takes to lose the weight gain. F 35 2 months
50
8/1/2017
  

ALDACTONE  (SPIRONOLACTONE):  Spironolactone is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems. This medication is also used to treat low potassium levels and conditions in which the body is making too much of a natural chemical (aldosterone). Spironolactone is known as a "water pill" (potassium-sparing diuretic).   FDA Approval Date: 1983-12-30 (Sources: U.S. Centers for Medicare Services, FDA)

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