DEPO-MEDROL Reviews (METHYLPREDNISOLONE ACETATE)

Average Rating: 1.9 (144 Ratings)

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 Type: Rx Drug

  

DEPO-MEDROL  (METHYLPREDNISOLONE ACETATE):  Methylprednisolone is used to treat pain and swelling that occurs with arthritis and other joint disorders. This medication may also be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/intestinal/kidney/lung diseases, and immune system disorders. It decreases your immune system's response to these conditions and reduces symptoms such as swelling, pain, and allergic-type reactions. Talk to your doctor about the risks and benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use. Methylprednisolone is a corticosteroid hormone. Methylprednisolone may also be used with other medications in hormone disorders.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-MEDROL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-MEDROLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Pain in T8 spine Had Depo Me from injection in T 5/6 area for pain in T8 in Nov. By December Strange spine feeling started. By March no sleep more pain then I ever had in my life. Burning low back pain into legs, Mid back and been neck. By April without any sleep I ended up with A FIB in hospital. Never had that before either. No doctor wants to discuss Depo Metro as suspect. Big cover up. I think I am dying slowly. No one cares. poison. M 70 1 days
Not told
4/28/2019
 1  1 shot for rotator cuff About 36 hours after the shot I developed severe anxiety and panic with tremors and nightmares. Today marks 4 weeks and I am still taking xanax to control the anxiety but I do think the symptoms are getting better. I was told today that we could do detox, some Ginger tea, sauna and exercise should all help to start moving this horrible medication out of my system. Never again F 50 1 days
80mg
4/18/2019
Email
 1  Allergic reaction to Benadryl When I got the injection in my arm my whole body went numb then fever,rash,hot,turned red, folliculitis,stomach aches, horrible dreams, depression,thought I was gonna die... That was eight months ago and I’m still not right been to six other doctors.. my potassium and testosterone very low and my immune system is very weak now!! Still having dizzy spells& muscle aches. I can’t believe there given people this mess. I was very strong and healthy before this shot now I’m going down.... this not right at all! M 43 1 days
80mg
7/27/2018
 1  Epidural I was 41 when I had an epidural which caused me to have stage 3 adhesive arachnoiditis disease and cataracts. My spinal cord fluid later became blocked from scaring. It has caused pain I had no idea existed, and cauda equina syndrome, and RSD. This is not curable. They are mutilating people and causing suicide allowing this. It's not a rare side effect, doctors just try not to tell you. I got my MRI records and found out after years of them lying and saying it was fybro. Even Pfitzer has asked for their drug not to be used on the spine! F 41 2 days
Unknown
6/20/2018
 1  RA, shoulder pain Joint pain, shoulders felt amazing however left me to feel like I am going through severe PMS, caffeine overload, heart racing and menopause all at once. I am only 9 days in so I am unsure how long this will last for. I will never do this again. F 44 1 days
6/1/2018
 1  SI-Joint Injection Heart Palpatation, tremors, feeling of low sugar, disconnected, short term memory; plus, only received 4 days relief. Had injection on 3/27/18; going on 8/weeks,, still having side effects. Would never had agreed to this injection had I known about size effects. Doctor, who injected, disclaimed any connection between DEPO-Medrol and side effects. Had to do my own research to find connection .Reported this adverse reaction to FDA. F 60
80 MG 1X day
5/24/2018
Email
 2  I had fractured collar bone . My arm can not move up and sore. Before taking this medicine my arm can move half way now it's difficult and so painful.thanks Not help for muscle pain. F 57 0 days
12/19/2017
 1  Yes Arm sore in injection site for 5 days. I started experiencing numbness and tingling...sweating ,dizziness sitting and standing,bad head aches and blurred vision,nightmares,mood swings,nervous...this shot is truly not worth all I had to go through ..I still have tingling,numbness,headaches..13 days today ..I just want to be like I was before this shot.. Will never get it again.. F 55 1 times
10/4/2017
 1  Piriformis syndrome, sciatica Pain much worse after injection. It has been 15 days since injection and still have redness at injection site. Could not sleep for several days. Therapist I am seeing now said I am terribly inflamed. I thought this was for inflammation and not to cause it. I can only hope this horrible soreness and pain goes away. I WILL NEVER HAVE ANOTHER!!!!!!! F 68 1 times
40mg 1X day
8/24/2017
Email
 1  Arm hand and shoulder pain I HAD DEPO MEDROL ABOUT 5 YRS AGO FOR ARTHRITIC KNEES WORKED LIKE A MIRACLE...WENT BACK TWO WEEKS AGO TO HELP MUSCLE PAIN IN NECK SHOULDER ARM AND HAND IT HAS MADE ME FEEL SO ILL.I SEARCHED THIS WEB TO SEE IF OTHERS HAVE HAD SIMILAR BAD REACTIONS...PAIN IS WORSE MUSCLES EVEN MORE KNOTTED NASTY DREAMS MASSIVE SWEATING EXHAUSTED WEEPY ACHE ALL OVER THIS AM DIARRHOEA TOO I JUST WANT TO CURL UP AND WAIT FOR IT ALL TO STOP SHAKY WEAK AND VERY DISAPPOINTED NOT WITH DOC HE VERY GOOD AND I HAVE FAITH IN HIM BUT THE EFFECT THIS TIME...DISASTER Obviously different at different times NO prob ist time..this time im crying aboutit all a lot and feel really low F 67 14 days
40mg
8/21/2017
 1  Broken tailbone with no relief 1st night of injection I was vomiting, severe heart burn, insomnia, and night sweats. Today is my second day and my face is beet red, heart rate through the roof, headaches and anxiety so bad my Dr had to call in adivan. Very scary. And what's sad is I asked the Dr yesterday was there any side effects and he said NO!!! Now from what I'm reading it takes MONTHS to get away from this F 39 1 days
Not sure
8/10/2017
Email
 4  Impingement Syndrome of Right Shoul My shoulder is okay. Some residual pain at different times of the day. Had shot on Wednesday and was fine Wednesday and Thursday. Friday woke up with Flu-Like symptoms. Bones hurt and have chills. Wearing flannel pajamas in August. Some rash on upper body. Never had Depo-Medrol Injection. Always Kenalog. Feeling like Crap. In bed all day Friday. A mac truck must of hit me in my sleep. F 56 0 days
Injection
8/4/2017
 1  Neck pain for years I had this injection in my neck 5 weeks ago and have experienced horrible anxiety, panic attacks, skin crawling, agitation, irritability, weird dreams. I have researched extensively and have found no answers to how long these side effects will last. I did see that the mechanism of action is 1-5 weeks so I'm hoping that I can get stabalized and taken off the klonopin I have been prescribed which is the only thing working to keep my anxiety at bay. Don't ever get this injection done EVER, if I had known the possible risks and side effects I would have never gotten it done! 5 weeks and counting and still no relief in site. My psych doctor is hoping I can be stabalized for the next 2 weeks so I can hopefully start tapering down the klonopin and deal with all the lovely withdrawal effects!! Do your research people please before getting this done!! F 27 1 times
80
5/13/2017
Email
 1  thoracic disc herniation Extremely high blood pressure. Racing heart. Faint. Made me insane. Loss of appetite. Motion sickness. Depression. Could not sleep. Skin crawly. Numb limbs. Extreme endocrine illness symptoms. Ear pressure. Eye pressure. Could not form sentences. could not think right. many many more awful symptoms for 4 months then alleviated a little at a time. I thought i was going to die. Never ever again for any reason! !!!!! F 46 1 days
160 mg
4/1/2017
 5  both knees Osteoarthriis Total relief from shot in each knee. No side effects. I have osteoarthritis and bone spurs in both knees with severe chronic pain and inability to walk or bike without legs locking and severe pain. A shot of Depo-Medrol in each knee lets me go back to free walking (without a cane) and bicycling without 99% of the pain. F 64 15 years
40 1X AN
3/24/2017
Email
 1  Frozen shoulder I received one Depo shot for frozen shoulder in Nov 2016. Approx 1 week after that I experienced heart rate up to 140, anxiety, panic attacks, 10 lb weight loss, depression and insomnia. Went to my GP who said it was not from shot, blood work was normal, she prescribed ativan, which I did not take. Starting seeing a Naturalpathic who said my adrenal function is low, even though blood work is within normal(but on low side) and symptoms probably due to shot. I am now on mega B, C and stress vitamins and take skullcap for anxiety. I am 4 months out and the lingering side effects are anxiety/depression and occas panic attacks, which my naturalpathic and I are working on. I have never had any of these before and they are quite debilitating. I feel better overall but by no means 100%. I exercise and eat healthy and all of these things help I think. Alcohol and caffeine makes symptoms worse.I am just waiting out these lingering symptoms and hope they subside in time. 57 1 days
not sure 1X O
3/15/2017
 1  Intrathecal injection I noticed after having epidural injections that I was very very prone to gastrointestinal issues. I consistently get a flu-like illness every 4-6 weeks from the time I started this as part of my pain management routine. Without fail every few weeks I would have this "flu" that joined around me ever caught. I have nurses, family, support workers etc around me daily and no one had ever caught it. Symptoms would be: *nausea (severe) has to be controlled with IV administered through peripheral IV daily, along with gravol. That is how severe the nausea had gotten). Fever 100-103 Racing heart when standing 120+bpm (I assume it would go hand in hand with my next symptom) Orthostatic intolerance- no would bottom out when standing. Was low when sitting or supine however I didn't have the same effects from being supine or sitting, compared to standing. Unable to stay hydrated. Due to vomiting. Unable to get comfortable. I would get hot and cold sweats that would change every 2 min. Way too hot and soaked in sweat so take layers off and would be freezing before I could get a heavy sweater off. No appetite whatsoever. Started off at 135lbs and I'm 5'5 female. I was getting sick very frequently around Sept 2016... and over that last year i had finally gained a healthy weight. I was 135lbs. Its now march. 3 and I am 112lbs. I was so weak from this "flu" I was unable to get out of bed. It was terrible having this every few weeks for a ye F 33 8 months
1ml-2ml
3/3/2017
Email
 1  Torn rotator cuff The 20yr old female that so confidently stated that side effects are short lived and go away, you are a moron! Common sense tells you that everyone is different and affected differently by numerous things. I had a disk removed and fusion of my cervical spine. When I awoke from surgery I felt amazing compared to the previous years of heavy arms and locked up muscles. One month later I was approved by neurosurgeon to have an injection of depo-medrol into my torn rotator cuff by the orthopedic surgeon. Afterwards I felt even better, the burning at top of shoulder was gone and I even expressed to my wife how amazing it was. By the end of the next day everything changed, my left side muscle in my neck became rock hard again and from top to bottom my trap muscle on left side was locked up also. Then my arm became very heavy and tired feeling. Then a few days later my sternum began to hurt very badly and the top side of my ribs were very tender to the touch. Eventually I couldn't pick up my 2yr old because I would get a traveling pain down left side of my back when I tried to lift her. It has now been almost 2 months since shot and I'm now taking Neurotin and muscle relaxers for minimal relief from the nonstop pain of constantly being locked up. This has been consuming my life. I have been depressed, angry, and dumbfounded that this shot has made me feel worse than before my surgery. My only hope is that since it is a 3 month interval shot that next month it will all stop. So 20yr old female, you're dumb as sh*t. M 37 1 days
1/6/2017
 1  Hip injection for pain After the injection in my left hip. It got worst. I cannot raise my leg. Hurts terribly to walk.cannot stand on it long. Bend I have limit mobility. This medicine needs to be taken off the market. F 60 1 days
12/22/2016
 1  Rotator cuff The shot relieved the pain in my shoulder but my blood pressure has soared, almost doubled, and my pulse randomly races to 100 or slows to 50. This is accompanied by a feeling of lightheadedness, fogginess and odd skin sensations ranging from itch to prickly sweat. It has now been two weeks and these side effects are showing no sign if diminishing. I would prefer to have shoulder pain. This is scaring the crap out of me. I've long been healthy with low BP. Don't do it. F 58 1 days
60 1X day
11/30/2016

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