Drug Safety Information for NORPRAMIN (Desipramine hydrochloride)

Adverse Drug Reactions for NORPRAMIN* (Desipramine hydrochloride)

These charts and graphs are based on reports received through the FDA Adverse Event Reporting System (FAERS) program (see below).

Top 20 Adverse Effects Associated with NORPRAMIN
(reported in FDA Medwatch/FAERS Reports)

  Side Effect # of FDA Reports
1Completed suicide112
2Fatigue56
3Nausea55
4Drug ineffective52
5Pain45
6Dizziness45
7Anxiety42
8Depression41
9Headache38
10Fall36
11Toxicity to various agents36
12Insomnia34
13Vomiting33
14Diarrhoea31
15Drug interaction28
16Hyperhidrosis*28
17Weight decreased27
18Death27
19Weight increased*27
20Arthralgia27

* This side effect also appears in "Top 10 Side Effects of NORPRAMIN " in the drug's Review Summary based on AskaPatient reviews.

Top 10 Reasons for Taking NORPRAMIN
(associated with FDA Medwatch/FAERS Reports)

Reason # of FDA Reports
1Product used for unknown indication462
2Depression*360
3Insomnia66
4Bipolar disorder57
5Phantom pain53
6Pain43
7Suicide attempt40
8Gastric disorder39
9Sleep disorder33
10Crohn's disease24

*Also a top-10 reason in AskaPatient Review Summary.


Types of Adverse Events for NORPRAMIN

Total Reports Filed with FDA: 4582


Number of FDA Adverse Event Reports by Patient Age for NORPRAMIN

Total Reports Filed with FDA: 4582*


* Reports for drugs with the same active ingredients have been aggregated in this analysis: Desipramine hydrochloride (Desipramine, Norpramin, Pertofrane)

Charts are based on 4582 reports filed with the FDA between 2004 and June 2015.

Adverse Event Reports are submitted to the FDA by pharmaceutical companies (mandatory reporting is required by manufacturers, distributors, or importers), health care providers such as doctors (voluntary reporting), and by patients themselves (voluntary reporting). More Information on FDA MedWatch (FDA Safety Information and Adverse Event Reporting Program)Voluntary reporting takes place under the FDA's MedWatch program, where health care professionals and consumers submit reports to FDA when they find a problem with a drug, medical device, biologic, or other FDA-regulated product. An adverse event is any undesirable experience or extreme side effect associated with the use of a medical product. Adverse events include: death, life threatening event, hospitalization, disability or permanent damage, congenital anomaly or birth defect, medical product use requiring a surgical or other intervention, or other serious medical situation believed to be caused by the drug.

Click to go back to search results and NORPRAMIN Reviews and Review Summary .

Historical Analytics of FDA Adverse Event Reports Provided by Druginformer.com. FDA Drug Safety Information, including safety-related labeling updates, required post-approval safety studies, risk evaluation management strategies (REMS), alerts, and recalls are compiled by AskaPatient.com from the U.S. Food and Drug Administration.