MESTINON Reviews (PYRIDOSTIGMINE BROMIDE)

Average Rating: 4.0 (82 Ratings)

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 MYASTHENIA GRAVIS

 Type: Rx Drug

  

MESTINON  (PYRIDOSTIGMINE BROMIDE):  Pyridostigmine is used to improve muscle strength in patients with a certain muscle disease (myasthenia gravis). It works by preventing the breakdown of a certain natural substance (acetylcholine) in your body. Acetylcholine is needed for normal muscle function.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender males first.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on MESTINON: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR MESTINONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Myasthenia Gravis Wild twitching in legs, and sometimes arms and face. It's actually amusing to watch my legs and toes, reminding me of the scarab beetles in THE MUMMY undulating beneath the skin, and my toes moving independently in ways I could never do intentionally. As my MG goes into remission, and I have reduced my dosage, the twitching is abating. Currently I am taking 3/4 tablet at 6 am, 10 am, 2 pm, and 6 pm, and then 1/2 time-span tablet at 10 pm. This is a wonderful drug -- a miracle, in fact. After a sudden onset of MG, I had a lateral robotic thymectomy. Prior to the surgery I was experiencing respiratory crises several times per week, had double vision, had become a clinical wimp. and was taking 90 mg of generic Mestinon every 3 hours around the clock. The surgery seems to be having its effect, and I am confident that I am headed for a significant remission. M 62 5 months
45 mg. 4X day
10/6/2011
 5  M G iam taking mestinon about 6 years now along with imuran i have just been told i have a skin cancer a side effect of imuran any advice welcome M 70 6 years
60 1X day
7/10/2012
 5  ocular myasthenia gravis some gas, esophagal spasms if gulping food down without thinking, shortness of breath, right branch of heart has a bundle block and Mestinon may be assisting this from getting worse... I have had reiki treatments by a lady who could re balance my energy shakras (s?)e and it worked for about 6-8 weeks at a time..but she is no longer available where I live...Felt like I was on top of the world afterwards.I am going to try it again (no side effects!) www.reiki-for-holistic-health.com/chakra-balancing-healing.html M 74 10 years
180 mg 2X day
8/20/2012
 5  MG Increased salivation periodically. Abdominal discomfort if taken on empty stomach (2 Ritz crackers with first dose preventive). Very rare diarrhea. Not a cure but much improved. Diplopia now problematic only when I don't get enough sleep. Can walk on level without difficulty. Hills a problem (walking hills brings on diplopia despite sleep). Slow walk no symptoms. M 63 3 years
60 4X day
3/7/2013
 5  post polio syndrome diaherra , eyes watering used off and on for post polio syndrome and unknown nerve/muscle disorders depending on which doctor I have. Most test determine muscle problems but unclear on specific reason. Always gives me more arm and leg strength. 120 mg about every 4 hours is usually the dosage I need if doing physical things. Great medication M 57 10 years
2/5/2007
 5  OMG Slightly watery eyes and a little extra salivating This drug has helped me greatly. Fortunately, a very small dosage (120mg total a day) has had the desired effect on my OMG and has almost entirely eliminated diplopia. M 35 2 months
1/15/2007
 5  ocular myasthenia gravis Initially, some tearing but now none. Two or more solid bowel movements a day. That is all Miraculous drug. Double vision was terrible. Now, to date, I am symptom free. M 70 10 months
10/17/2008
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 5  Ocular Myasthenia Gravis When taking the Timespan Version slurred speech, weak jaw, abdominal cramps - None when taking 60mg Mestinon This medicine helped me through two pregnancies as it allowed me to get off the prednisone which can have really bad side effects after long term use. I can lead a symptom-free life on this. I started on the Timespan version and only got the normal version when there was a shortage of mestinon and no chemist could get it. What a blessing in disguise as the 60mg version works fantastically without any of the horrible side effects that I used to get with the Timespan Version. M 35 4 years
9/24/2007
 5  diagnoses with myasthenia march 09 stomach cramps, loose unfinished bowel movements, urge to defacate, although its cured my vision problems, associated to MG, the stomach problems and bowel movements are like a prison sentence to me, Im nervous about travelling, never know how Im going to feel one do to the next. M 54
5/13/2009
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 5  mg Frequent urination heavy sweating, sometimes headaches but on the whole has made life much more enjoyable, dosage just increased as previpius dose was not lasting 4 hrs only 3 then one eye would shut,and I would get tired, without mestion I would be a mess ,but now have never felt stronger side effects I can live with mestion amazing!! Mg is a horrible disease but with mestion you can look and feel somewhat normal!!!! M 46 4 weeks
360mg a da
2/18/2014
 5  Ocular Myasthenia Gravis (my son) My son has twitching in his arms, legs and stomach every now and then. He gets stomach cramping sometimes and loose bowel movements. My son was diagnosed with Ocular Myasthenia Gravis a little over 2 years ago, right before his 6th birthday. My husband and I noticed that my sons left eyelid was extremely droopy. After blood test and eye examinations he was diagnosed with Ocular MG. He started off taking 10mL of Mestinon 4x's a day, then about 6 months later it was reduced to 8mL 4x's a day. Towards the end of 2013 the neurologist took a dose away and he was taking it 3 times a day. Three months ago the neurologist took away another dose so he was taking it 2 times a day. We had an appointment yesterday and she still wants my son to take it twice a day, but she dropped it from 8mL to 6mL. This medicine is truly amazing. My son's eyelid has not drooped since he's started taking mestinon, and all of his muscles throughout his body are very strong. I am very thankful to God for this medicine and for his neurologist and ophthalmologist. Though he does have the cramping, twitches, and loose bowel movements from time to time, I think this is a great medication. M 8 2 years
60mg 3X day
8/21/2014
 5  have mg cramps in hands, calves and muscles in back of shoulder. loose stool I take 90mg four times a day. Using this medication let me regain my life.I take Mestinon along with a anti rejection drug named cellcept (Mycophenolate generic). My symptions of MG were diffuculty breathing,drooping eyelids, chocking,couldn't support my head upright, extreme muscle weakness,sleeping approx. 22 hrs per day. Doctors didn't expect me to make it. Good doctors and good medication and a great creator. M 65 5 years
11/25/2009
 5  MG Stomach aches if on a empty stomach. works great and its fast. M 75 1 weeks
30.3x a da 3X day
4/21/2022
 4  Myasthenia Gravis Twitching of both eyes, Neck pain, Diahroea,nausia, stomach cramps. I was diagnosed with Myasthenia in 2006, had a full transfusion of infogram, didn't work, Had a thymectomy to remove the thymus and associated tumor. Had radiation treatment on the cancer discovered during the operation. Symptoms held steady for 12 months after the operation, now getting worse by the day. Must always be in sight of a toilet, which makes it impossible to travel. Currently taking Mestinon, Imuran, Prednisone, but still getting worse. Gets that bad that I'm actually disappointed that I wake up. M 51 3 years
10/26/2009
 4  MG Constipation: I usually manage this by eating fruits and vegs regularly Dry skin: when I increase my dose to manage "extra effort" days. I use creams. Slight muscle twitching: not major I've just been diagnosed with MG a month ago and Mestinon has made a huge difference in my life. I am still struggling to figure out the right dose for me given my lifestyle and level of activity. I take 3x60 and 1xTR every day and I am still struggling with overdosing/underdosing and controlling my most prominent symptoms (swallowing, eye, nec) M 52 1 months
60 and TR 4X day
7/6/2020
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 4  pps and unknown muscle problems diarreha , dry eyes some doctors don't like prescribing mestinon because I don't have myasthenia. Find when I'm on mestinon I always have more arm and leg strength and less leg pain. Dosage various but usually 4 to 8 60 mg tablets daily depending on what I,m doing been taking off and on since 1994 M 57
3/20/2007
 4  Myasthenia Gravis I have taken 720 mg per day at first plus 150 mg of imuran and it took 36 mouths before the imuran started to work properly. At high dosages 60 mg @ 5 plus a day diarreha plus bleeding as dosage increased. I have worked myself down to 60 mg x 2 now but i have had problems with Erectile Dysfunction for 10 yrs and high blood pressure. After about 12 months i was able to return to work but stress ended that in 5 months. I adjust my dosage myself and i am going to try to stop the Mestinon completely and just rely on the imuran. It dose mess with urination, more spiting, nasal draining. M 67 15 years
60 2X day
11/9/2017
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 4  Myasthenia Gravis Unpredictable and strong bowel movements. Loose Stool. Some Diahrria. Contracted full blown MG in March 2009. Breathing, swallowing, eyes and tongue paralyzed. Spent 9 weeks in the hospital and 4 weeks in rehab. Currently taking one 180 MG Timespan pill per day. Tried increasing it to two per day to improve swallowing difficulty, but bowel problems were too bad. Had 5 IVIG infusions which helped a lot. Plasma Phoresis really helps, but is risky. M 79 8 months
180 MG 1X day
2/13/2010
 4  MG Gas, loose bowels, best if taken with food but I handled it ok when I just took it straight. I take a 180 time span at night and feel great in the morning and then I take a 60 mg 2 times a day. Keeps me going. It is a very effective drug for MG. I have had Mg for a little over a year and it made a lot of difference. I had my thymus removed and I am getting along pretty well. I am about 75% of what I was before. The mestinon is making life good again. M 59 1.2 years
180 1X day
3/9/2010
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 4  Myasthenia Gravis Terrible diarrhea until I started taking Loperamide Anti-Diarrheal evey day. Still get severe cramping in hands and fingers. Doc has prescribed potassium for cramping. Also get twitching eyelids when taking Mestinon. Vision has gone from 20/20 to 20/40. had Seem to have to urinate every 5 or 6 seconds. Was also taking 60 mg Prednisone, now down to 20 mg. Still bruise or cut for no good reason. Still weak after 3 months. Tried to play golf yesterday and I hit the ball about as far as my 150 year old grandmother. Still get dizzy without warning. Followed up with bleeding ulcer that my doctor said was caused by Prednisone, then pneumonia, so 3 separate trips to hospital. Hope it's all over now. M 71 90 days
360 mg 1X day
5/6/2010
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MESTINON  (PYRIDOSTIGMINE BROMIDE):  Pyridostigmine is used to improve muscle strength in patients with a certain muscle disease (myasthenia gravis). It works by preventing the breakdown of a certain natural substance (acetylcholine) in your body. Acetylcholine is needed for normal muscle function.    (Sources: U.S. Centers for Medicare Services, FDA)

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