Drug Ratings for PLAQUENILAverage Rating: 3.3 (567 Ratings)
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Results are sorted by length of time drug was taken from shortest to longest (with no time reported listed first) Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
| RATING | REASON | SIDE EFFECTS FOR PLAQUENIL | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
  | F M | | | | |||
| 5 | Lupus | I haven't experienced any side effects. | This is my second time taking plaquenil/hydroxychloroquine. 200mg 2 times a day. I was first diagnose of lupus in 1995. I went in remission in 2001. I decided to stop taking plaquenil. I had no symptons in the last 4 years. About 2 months ago I start having swelling and pain in my feet. So I started back taking plaquenil. I'm now back feeling great! | F | 33 | | 4/22/2005 | 5 | Scleroderma | Stomach cramps | Due to the stomach cramps, my Dr. had me start with 1/4 of a tablet and work up from there. I am still in the first week but so far, I am feeling SO MUCH BETTER. My joint pain and fatigue are going away and I am still on 1/4 of a 200 mg tablet. Good luck to everyone and thank you for this site. It was very helpful. | F | 53 | | 4/29/2008 | 5 | Connective Tissue Disease/Lupus | None | I had such bad pain I couldn't walk without my bones cracking. I take plaquenil everyday 200mg. It has truely improved my life. Still pain bothers me every now and then, but I wouldn't be able to go on without this medication. It has helped me ALOT. If I miss taking the pill for a few days, I notice a big difference. | F | 18 | | 3/23/2009 | 5 | Lupus | No side effects. I've been taking Plaquenil for three and a half years. | Since Plaquenil is a disease modifying drug, I would be afraid to be without it. It can do wonders for Lupus symptoms and keep antibody production down. I think it can make a big difference long term in the severity of Lupus. | F | 46 | | 5/7/2009 | 4 | Lyme - lyme artrosis | Gas.... I noticed vivid dreams, no problem, I like it. Bit lightness in the head perhaps... We will see coming months. | I read all about Plaquenil on this forum, and I'm very thankfull to you for all your input. The plaquenil was taken shortly after the meal 2 times a day 200 mg. I also use Doxycyline 4 x 100 mg/day. It seems to start working just after an hour or so after the FIRST dose... (placebo-effect???) Now, after 3 days, I'm free of hip and back (lumbal- low spine) pain. I realize it's not over yet, I will continue using this combination for about 3-4 months. I bought my Sanofi-Aventis plaquenil at Goldpharma.com, because no doctor in the Netherlands believe in Lyme desease... (except 1, Dr. Kingma of the Walborg Oosteneinde clinique in Amsterdam. We live in a country with a hoplessly outdated medical culture. | M | 47 | 200 1X D | 10/18/2010 History | 4 | inflammatory Arthritis etc. | I believe my stomach aid and some nausea were some side effects, and dizziness. I have only taken for a short tiem now, but my knee and joints are already feeling much better, so it has helped. | F | 62 | | 7/5/2005 | 3 | Rheumatoid Arthritis | Upset stomach, headaches, running nose, swelling of joints, extremely sensitive eyes. | I haven't been using Plaquenil for long, so I guess it hasn't had enough time to start working properly, but I'm not sure whether I want to keep taking it or not, due to all the side effects, I'm not sure if it's really worth it? | F | 16 | | 1/28/2008 | 3 | LupusI | I worry about the side effects it can possibly have on your eyes | F | 69 | | 8/23/2003 | 3 | LupusI | Mostly discororation of the lower arms some on the hands< I have never come off the Plaquenil since I first started taking it. I was wondering about the real long term effect. | I worry about the side effects it can possibly have on your eyes | F | 69 | | 8/23/2003 | 1 | JRS | uncontrollable muscle twitches that have remained for years, permanent nerve damage | I went to the ER with uncontrollable muscle movements a couple years ago. My doctor said it was the plaquenil. My fingers still twitch, but not as badly since I stopped the medicine. I had also had caffiene during the inital twitching episode. | F | 17 | | 2/6/2009 | 1 | erosive arthritis | Started taking plaquenil on March 28 after seeing the eye doctor. just took once a day...instead of twice. because was getting heartburn at night from it. on Friday, April 23, almost a month later....I noticed my skin was bumpy. on Saturday my torso was covered with small red spots. my arm was covered was raised red patches. Sunday I did not take the medicine. rash is getting worse and itchy. The red patches are still bad. Will call the doctor tomorrow. Monday. still itchy, bumps red. Called the doctor, they did not return my call. Tuesday not as itchy, still red, but bumps not as prounounced. still blotchy red on my front torso. Went to the pharmacist at cvs, he told me that they have not had problems with plaquenil, and that if the rash was from plaquenil i would have had the rash immediately, not 4 weeks later. I wanted to tell him he he was clueless. Wednesday, still blotches on my torso, top of my arms seems to be not as inflamed. upper back part of my arms s | Why don't doctors and pharmacists ever believe you ? Thank God for the internet and real people who share their real experiences on it! I now see why some people go for all natural solutions. I am getting disgusted with doctors and their lack of belief that a medicine could have a side effect. | F | 54 | 200mg 1X D | 4/27/2011 | 1 | RA | M | 60 | 100mg 1X D | 6/10/2011 History | 3 | osteo arthritis | about to start taking it for a 2nd time. found it very effective but it made me photosensitive, which was impossible to manage in the australian summer. And it gave me terrible body odour. | Its now winter so I will start taking Plaquenil again and will try to stay out of the sun. Got a rash and itching if I was exposed to any sunlight. Will have to ask my doctor about taking some Vit D as a top up. Also last time it gave me terroble body odour, I needed 3 showers per day. | F | 47 | 2 times | 6/2/2009 | 5 | RA /LUPUS/ OSTEOARTHRITIS | NO SIDE EFFECTS | PLAQUENIL HAS MADE A HUGE DIFFERENCE IN MY LIFE....SO I HAVE SOME VISION LOSS, THE BENEFIT OF THE LARGE DECREASE IN JOINT PAIN HAS OUTWEIGHED THE VISION...I CAN GET UP AND WALK IN THE MORNING, AND HAVE A PRODUCTIVE DAY!! | F | 43 | 1 days | 11/19/2003 | 4 | Lyme disease | Major Gas, vivid dreams, extreme forgetfulness, itchy skin,lots of new freckles on back and arms, extremely bad taste in mouth all day and night. | I don't know if this drug has worked or not yet. The side effecta are manageable. I hope it works!!!!!! | F | 36 | 1 days | 2/5/2008 | 3 | lupus | within 2 hours of taking the medication, I experienced diarrhea/bloating/gas pain/flatulence. | F | 38 | 1 days | 2/25/2009 | 1 | Rheumatoid Arthritis | After 1 dose - severe muscle cramping and spasms for over 24 hours. It seems to have to triggered my fibromyalgia which was almost under control with medication (Cymbalta), and caused a worse flare of my RA - joint swelling and pain increased considerably. | I was really hoping Plaquenil would work as it's one of the safer Rheumatoid Arthritis treatments. | F | 38 | 1 days | 3/30/2009 | 1 | UDCTD | Took first 200 mg pill with food. No side effects for first 20 hours, then nasty diarrhea,stomach nausea, stomach cramps, dizzy,gas, burping, feeling spacey, black out when standing, felt totally out of it - basically non functioning. Terrible brain fog. Forget about driving, going to work, or doing anything other than praying for the drug to get out of your system. Effects lasted for three days, diminishing with each day. Never took a 2nd pill. Also developed sore/scratchy throat which continues at day 3 but doc says not from Plaquenil. Coincidence is too strong. Not on any other medication I can blame. | Could not tolerate 1 pill let alone taking it long term. I think doctors should stop calling this a safe drug. It has terrible side effects even for those on this site that give it a 5. Exchanging one set of intolerable symptoms for another is a poor choice. Sad that a drug that was used in the 1960's for autoimmune is still the gold standard. But hey, we can now cure erectile dysfunction. Medical progress... | F | 50 | 1 days | 5/26/2009 | 5 | Sjogrens | flatulence; I am more aware of the neuropathy in my hands and feet | I am a physician. I thought it would take weeks to have any benefit. Within hrs my fatigue was gone and the fogginess in my head had cleared. I thought it was a placebo effect but after reading the other comments, I guess it is real. So far it has given me my life back | M | 56 | 2 days | 1/15/2009 | 5 | Yes | Crazy vivid dreams too. I also feel a little light-headed. | F | 38 | 2 days | 3/4/2007 | 5 | RA | None really. I felt a bit more energized and that's why perhaps sometimes have problems sleeping...and sometimes also more vivid dreams. | This medication has really worked for me. I was taking Nabumetone for 3 years, but I'd have flair ups and would feel it and also had terrible stomack problems. Now ever since on Plaquenil I feel great. Only on several occasions I felt a little tingling in my fingers, so I knew that if I wasn't on Plaquenil this would be a painful flair up. No itching, or hair loss. This medication makes skin much more sensitive to sunburn, so maybe, if one is not careful, this can cause sunburn, itching, etc... | F | 40 | 2 days | 4/29/2007 | 3 | RA | I am not sure if this is a side effect, but I have had EXTREME GAS. I have recently started having a ringing in my ears also. | At first the plaquenil worked, then when my pain increased my Dr. put me on Remicade and Methotrexate too. I am wanting to stop the plaquenil to see if it is causing the ringing and the gas, but I have a great Dr. and I would not stop it unless he says to stop it. Anyone else have ringing in the ears? The ringing just started 3 weeks ago. | F | 54 | 2 days | 10/7/2003 | 3 | Rheumatoid Arthritis | I just started this medication yesterday and my 1st dose my lips felt funny and I got this metallic taste in my mouth. Then during the night my instestines felt gurgly . Today was my 2nd dose and I got the taste again in my mouth again. Then I just felt loopy and I am not sure why that is. I am going to stick with it and see what happens and hopefully it will help me and the side effects will go away. | I am super scared about the eye side effects. This seems like a very dangerous drug and I am making sure that I pay attention to all of my side effects. Oh, I also got a sore throat after taking these 2 doses. Anyone else ever get a sore throat after taking it? Weird for sure!! | F | 42 | 2 days 200 2X D | 1/9/2012 | 1 | Chronic Lyme Disease | hives | The itching I experienced was unbelievable. I took this drug for only 2 days and it took 21 days for the hives and itching to clear up. It was just a horrible experience. Since I was prescribed Biaxin as well, I don't know for certain which of the two caused the itching, but I very much doubt that I will take either one again! | F | 59 | 2 days | 5/12/2006 | 5 | SLE | CARDIOMYOPATHY, rare side effect , I now have severely hypokinetic inferior wall of my heart | F | 45 | 3 days | 10/27/2003 | 5 | RA (stills disease?) | nausia and gas | I was extreemly ill for three years, I was completely debilitated and the doctors did not know exactly why-althought they all agreed it was autoimmune RA JRA Stills Adison... Anyway I had extreem fatigue, daily fevers, hair loss, swollen joints. I was put on sulindac (this is the best NSAID I ever found and I tried all of them including the COXX 2s) and then six months later plaquenil. The plaquenil got rid of the fevers, morning stiffness, fatique and hair loss. I felt human again. Eventually the disease was in a remission deep enough that the plaquenil side effects ( just GI symptoms) were worse then the disease. I stayed in partial remission for seven years. I had a bad flare last month and the first thing I did was ask to be put back on Plaquenil. | M | 36 | 3 days | 12/3/2007 | 5 | sjogren's syndrome | none | After just three days, my fatigue has lessened and I no longer feel mentally sad...it actually has improved my mood and I will start exercising again...beside sjogren's i have hasimoto's thyroiditis so any relief of symptoms are fantastic...so far, so good, I love this medication. | F | 56 | 3 days | 1/9/2009 | 4 | SLE | nausea, stomach cramping, slight headache | i 've been on plaquenil for only 3 weeks. when i started taking the drug i had already been in remission from all of my symptons since september 2002. so i can't say that it has helped because i haven't had any SLE flares before or after taking plaquenil. | F | 34 | 3 days | 4/26/2003 | 3 | Lupus, Sjorgren's, Auto Cirrhosis | Bloating, intestinal gas pain, dizziness, mild headaches, lowered energy level, insomnia. | Currently taking 200 mg a day. They are trying this after lowering my Prednisone from 30mg to 20mg. They say the long term side effects will be better with Plaquenil but I felt better on Prednisone. | F | 61 | 3 days | 9/12/2007 | 2 | SLE | allergic reaction(hives over body; extreme with hands and feet burning, itching and peeling) | M | 55 | 3 days | 2/4/2002 | 2 | MCTD | At the end if day two, I experienced the worst diarrhea I think I've ever had. It lasted well into the next day. It was very painful and even burned. I'm taking half the prescribed dose. Also have broken out with little pimples on my face, chest and back. | 40 | 3 days 200mg/day | 5/13/2013 | 1 | Lupus/Auto Immune Hepatitis | Extreme fatigue, itchiness,nausea, vomiting,diahrrea | I dispise this drug, every since my doc put me on it Ive felt sick and tired. Ive not been able to keep any food down. | F | 31 | 3 days | 3/27/2006 | 1 | suspected lupus | ringing in the ears, visual disturbances, trouble sleeping, hair thinning. initially, the joint pains subsided, and i felt good about taking the drug. but after 2-2 1/2 months, joint pains came back, and i decided no way, not dealing with the pain and the side effects. i've started taking zyflamend (herbal type remedy. been on for almost two weeks, not alot of response yet, but am hoping.) | i've been off of plaquenil for well over a month, wish someone would clue me in as to when i can expect the hair loss/thinning to subside. | F | 37 | 3 days | 11/12/2004 | 4 | Lupus (SLE) | Only had diarhea for the first few days, it subsided and now it has been good. | I think this drug is good but regular eye checkups should be done in order to catch any horrible side effects. | F | 29 | 4 days | 11/13/2003 | 4 | RA | GASSY, FOGGY MEMORY, BRUSING, NIGHTMARES. | I'M A LITTLE NERVOUS ABOUT TAKING THIS DRUG. MAYBE IT SHOULD BE ALOT NERVOUS. THE MEMORY INTERFERENCE IS WHAT SCARES ME MOST. I FIND MYSELF FORGETTING HOW TO USE MY FINGERS ON MY KEYBOARD. | F | 54 | 4 days | 1/27/2009 | 2 | Lupus/Behcets??? | Shakes, sweats, fast heart rate, funny head exactly like a hypoglycaemic attack except blood sugar levels remained normal. | I had to stop plaquenil because of these side effects which are not documented. A second trial after stopping the drug (with no symptoms inbetween) elicited exactly the same reaction | F | 40 | 4 days | 10/27/2002 | 5 | SLE | Stomach cramps, diarrhea, and gas, all lasting only about 1 week | Started with a blood clot in left leg in Feb 08. Was diagnosed with Lupus Anticoagulation and was put on Coumadin for the rest of my life. Other symptoms began appearing shortly after the clot (TMJ, rashes on arms, joint/muscle pain, hand swelling, fatigue). Was finally diagnosed with SLE in July 08 but it was 5 months of pure hell not knowing what was wrong with me, one symptom after another popping up with no relief in sight. Started Plaquenil last week. Was told it would take about 4 months before seeing any results. However, after less than a week, have already noticed a good amount of decrease in muscle/joint pain and increase in energy level. Like many others on this site, I feel like I've gotten my life back and now have a renewed hope for my future and living with this disease. | F | 44 | 5 days | 8/20/2008 | 3 | erosive inflam osteo both hands | possible photosensitivity, feeling a little wired, no GI | Hard to sort it all out in light of simutaneous taper of darvocet(bad drug for chronic pain)and use of NSAID only prn now. I also have found intjection into joints under fluor as outpt procedure very helpful to function-I have need to hand right for my profession and I've accepted a new project | F | 67 | 5 days | 4/18/2009 | 3 | Severe Chronic Urticaria | Diarrhea, loss of appetite, fatigue | Today is the 5th day taking Plaquenil 100mg daily. It is also the first day ive had pain free! Although very tired, no pain is definitely worth it! It has also been 5 days since i have had a flare up of other symptoms. Next week i start on 200mg a day. I almost cannot wait. I am hoping this also means i can slowly decrease the amt of steroids i am taking! My fingers are all crossed!! | F | 30 | 5 days | 4/24/2005 | 3 | Severe Chronic Urticaria | Diarrhea, loss of appetite, fatigue | Today is the 5th day taking Plaquenil 100mg daily. It is also the first day ive had pain free! Although very tired, no pain is definitely worth it! It has also been 5 days since i have had a flare up of other symptoms. Next week i start on 200mg a day. I almost cannot wait. I am hoping this also means i can slowly decrease the amt of steroids i am taking! My fingers are all crossed!! | F | 30 | 5 days | 4/24/2005 | 3 | Lupus like symptoms in hands., | The medication helped my Raynauds symptoms and reduced the redness and swelling in my hands. I was taking it with an anti-inflammatory, Sulinac and 5 mg of Prednisone every 2 days for 5 weeks and broke out in a rash all over my body. They upped my prednisone to 30 mg and after 5 days I am still waiting for my rash to disappear. | The medication seemed to help and my doctor wants to put me back on it after the rash disappears. | M | 49 | 5 days | 6/29/2005 | 2 | Skin conditions related to lupus | I was prescribed it as I am diagnosed with auto-immune disease. I have skin conditions stemming from it since childhood. My mom took my off Plaquenil as a kid for a reason, but now I'm older, I decided to restart the course and this is my 5th day and the irony is that I am experiencing small blisters on my palms and sole, and a patch of rash on my back and arms. I don't know if I should continue. I would appreciate any sort of advises. | F | 21 | 5 days 200 1X D | 4/13/2010 | 2 | Lyme Disease | Headache (all the time!), nausea/anorexia, general stomach ickiness, dizziness. | (Note: I started plaquenil simultaneously with zithromax; it may be that some side effects resulted from the latter. I think it's mostly the plaquenil.) Side effects began soon (within 24 hours) after I started taking it. I stopped taking it over a week ago, but the side effects still have not subsided. Due to stomach problems, I have to FORCE myself to eat, I can only choke down a bit of fruit anytime before 4 or 5 pm, when hunger simply wins out over stomach upset. Meanwhile, I have had a nonstop headache; it waxes and wanes, but sometimes is almost migrane-like in severity. I have continued working but not with my usual efficiency. IMPORTANT QUESTION: How long did it take side effects to end? I was surprised to find that this drug can take 1-2 months to be completely eliminated from the system -- does this mean that I could have side effects for that long? :-( I have stopped taking the zithromax, in case side effects are related to that drug; the zithromax takes a week to clear, so if I still have these problems in a week, it's caused by the plaquenil. I will update then. I am reluctant to rate this medicine because I did not take it for long enough to see if it would have helped (and lyme disease isn't one to respond immediately to antimicrobials, anyway). I'm giving it a 2 for side effects. Had I known more about the side effects, I still would have tried it anyway, because many people are able to take it without problems. | F | 36 | 5 days 200 2X D | 6/12/2010 | 1 | Dermatomyositis | I left the review below, this is a follow up on my condition: | I withdrew myself from plaquenil n rushed to my derm who immediately put me in hospital for observation. By then I'm running a high fever, rash, swellings oh lips tongue and lymphnodes. My face is also pustulating. While the doctors were checking me, I heard them using the word "DRESS syndrome" a couple of time and I went to google it to find out that it is a severe reactions to drugs with High mortality rate of 10% with a high possibility of damaged organs e.g. Liver, kidney, lungs n hepatitis of 50%. I was give prednisone n the fever came down and I'm crossing my fingers n hoping to turn out well. I hope anyone who's considering plaquenil PLS research thoroughly and not end up like me...ask questions n make sure you're not allergic to sulphate or has history of dermatitis conditions, which will retrigger and bring out the worst. | F | 21 | 5 days 200 1X D | 4/16/2010 | 5 | SLE | Didn't have any at all.Have been on it for 6 years. | It has helped me tremendously,especially in the area of joint pains. | F | 67 | 6 days | 10/27/2005 | 5 | autoimmune (SS or Lupus?) | I have been on the drug for about 6 months. My skin seems to itch a little more but that could also be the thyroid condition. | To me, it is a miracle drug. Before Plaquenil, it was a feat to just make it out of the bed. My doc had tried flexiril which helped my restless legs and I could actually stay asleep for most of the night. She added cellebrex which was also a big help. It took a little over 3 months for the plaquenil to really kick in. And once it did, I was able to begin living a pretty regular life again. Before taking this drug I was missing at least a day of work every week - 2 weeks. And on the days that I managed to get out of bed, it took all I had to make it through the day whether working or not. The fatique has been the worst part of my illness. I am now reducing the amount of flexiril and cellebrex that I take. I can now work 10-11 hours a day but I keep a pretty rigid bedtime. I told my doc that I don't really care what name my illness ends up having - I just am so grateful for this drug and all it's benefits. I still have flareups when I spend most of my weekend resting whereas before I spent most of my life resting. It really is a wonder drug! | F | 51 | 6 days | 8/29/2003 | 5 | Eosinophilic fasciitis | little gas and feeling tired a bit (body feeling heavy!) | only just started not done a week yet but swelling has gone done so much have more flexibility in ankles joints (where problems are)its amazing - so pleased so far after being on steriods for over 10 yrs (still are due to reduce if this drug works! i do hope so!) | F | 35 | 6 days | 6/10/2009 | 1 | ra sle | severe nausea hair loss ring in ears and hearing loss no sleep for 36 hours | so much nausea i could not even get a sip of water down. falling hair was everywhere-bed,clothes, all over bathroom floor. the ear ringing was so loud could not concentrate on anything as well as significant loss in one ear. the day this all started (only day 6)! i went 36 hours with no sleep. this drug is poison. i will take my pain and manage it any day before doing this again. | F | 65 | 6 days | 11/20/2008 | 1 | Lyme | THINNING HAIR!!! | After being warned of eye issues, I took this drug and hoped for the best. It didn't help my symptoms and coincidence or not, my beautiful hair started falling out and has thinned. It's also not cheap if you don't have Rx coverage! | F | 6 days | 11/5/2002 | 1 | arthritis | pustular psoriasis | The drug was discontinued. After receiving systemic and topical corticosteriods, methotrexate etc, showers of new lesions appeared daily and progressed to involve 100% of my body. All my skin peeled of over a period of 2 months. After the medication was toned down the pustular lesions flared. I also developed a cyclical poly-morphonulear leukocytosis. Internal organs and eyes were affected. All my hair fell out over a period of 3 months. | F | 42 | 6 days | 1/16/2002 | 1 | RA | Blurry vision, floaters dryness | Didn't help mouth sores still had fatigue, joint pain | F | 38 | 6 days | 2/1/2008 | 4 | rheumatoid arthritis | Just developed itchy rash on elbows & knees. Hope I dont have to stop taking it. | F | 61 | 7 days | 11/24/2003 | 4 | DISCOID LUPUS | UPSET STOMACH PAIN LOWER BACK BAD DREAMS SOME DAYS OK | RASH HAS CLEARED 50% WILL WAIT UNTIL CLEAR WILL CUT TABLETS DOWN TO 1 PER DAY | F | 54 | 7 days 200 2X D | 2/8/2010 | 3 | hair loss | headaches | I just would like to know if anyone who is taking Plaquenil and this helped their hairloss | F | 25 | 7 days | 1/5/2006 | 3 | hair loss | headaches | I just would like to know if anyone who is taking Plaquenil and this helped their hairloss | F | 25 | 7 days | 1/5/2006 | 2 | sjorgren's syndrome | severe hair loss, depression | notice massive hair loss after taking it for a week. Now I stopped the med but the hair loss continues, although to a lesser extend. If I were to continue taking it, I would be bald by now. | F | 58 | 7 days | 8/15/2007 | 3 | lupus | A little dizzy & gassy(finally can get back @ my boys!)but new symptom is a fullness feeling in neck/throat & the need to clear my throat. Any one else experience this? | F | 47 | 8 days | 2/29/2008 | 2 | RA | headache,nausea,extreme gastrointestinal upset, muscle cramps and frequent copious nocturnal urination (anyone else?) | I have had severe arthritis symptoms for about a year now. Initially treated with a combo of NSAIDS and prednisone, I experienced great relief. As time went on these meds stopped working and Enbrel was added...finally plaquenil was prescribed to enhance the others meds..I feel like with each pill I am taking poison..I've never had a medication affect me so profoundly..with each dose I am more sickly than the day before..after reading the reports of others, I can't help but have severe reservations about continuing this medication..considering living with a higher acceptable level of pain vs unbearable nausea...I have temporarily stopped taking it until I consult MD | F | 51 | 8 days 200MG 2X D | 4/1/2012 | 5 | Ray's, Fibro and undiagnosed | Extreme stomache cramps and some confusion but overall starting on 100mg and increasing to 400mg after 3 days, I've been feeling better and better since day one! | F | 34 | 9 days 400 | 6/28/2012 | 5 | mctd | none | Amazing drug. I've been back on it for 9 months (post pregnancy) and it has improved my disease progress tremendously! I used to wake up with swollen hands, and so sore I dreaded getting out of bed. Now I wake up with no pain to speak of, and the worst I feel is a little bit achey on some days. When I'm off of it I can't function well at all. It has been a lifesaver. | F | 33 | 9 days | 4/8/2006 |