PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender males first.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  RA Interesting dreams but occasionally violent. (I am a very calm person and have been told I have nice humorous personality.) Strong metallic taste. Urine has metallic odor. Increased sensitivity to light, taste, smell. Minor change of hair color from light gray to reddish-brown. This is a fantastic drug and has allowed me to manage my RA with minimal flair-ups. I was originally treated with prednisone. After six months I was given both the prednisone and 200mg x2 daily for about 16 months until I had sufficient plaquenil onboard. For the past four months I have used only the plaquenil and tolerate it well. This has been a perfect drug for me. I had very debilitated and severe pain in my hands, wrists, shoulders, upper arms and hips which came on very suddenly at age 75. I had difficulty sleeping more than an hour and then usually only in a chair. Walking, showering, and any exercise was very painful. Today I walk and do moderate exercise, build furniture, work in the garden and just about anything I like. M 77 2 years
200 mg 2X day
3/13/2010
Email
 5  arthritus My first medication was prednesilone which while it worked ok it had side effects. My testes shrank to the size of grapes and I gained 20kg of weight, this went on to cause heart disease. Plaquenil has worked really well with only some itching when I first started taking it. Now I have concerns that I am experiencing muscle weakness and tremors particularly in my right arm M 55 3 years
20 2X day
9/16/2010
 5  for hand and feet pain None that i noticed It is not supposed to help my condition(small tissue neuropathy) but i started taking it bacause i was misdiagnosed for arthritis and nothing worked.When a neurologist figured it out it was neuropathy he said to start Gabapentin which i did and it helped.later the neurologist and rhemotologist said to stop placquenil.After 6 weeks off the Placquenil my discomfort got a little worse so i just went back on it for a 3 month trial. i am still taking the Gabapentin M 65 10 weeks
100MG 1X day
5/26/2011
 5  Inflammatory rheumatism none that I notice I was in agony before taking it. Took about a month to kick in and it has saved my life and career. I have my eyes checked six-monthly but have had no problems. M 64 17 years
40mg 1X day
9/14/2011
Email
 5  SLE I have been taking plaqeunil for the past six and a half years and have experienced only minor side effects. I had some hair loss at the beginning of my treatment but it has since stopped.I occasionally experience headaches,some vision disturbances and ocular migraines and the occasional fever, but otherwise I feel amazing. At first my energy level was not improving but over the past three years it has improved greatly and I feel completely normal. The joint pain and inflammation has diminished completely except for the occasional flare up. It has done wonders for me and has replaced my need for prednisone which makes me extremely happy! I make sure to visit my eye doctor at least once every six months to catch any eye problems that can occur. M 22 6.5 years
10/21/2008
 5  rhumetoid arthritis Stomach aches if I take on an empty stomach It took a long long time to kick in. I almost went to Enbrel because I was getting fustrated. Luckily doctor was on leave for a couple months so I had to keep taking it. It finally worked and now I have barely any joint pain (and been through several cold and rainy months). It took a good 4 months to kick in. M 45 6 months
11/27/2004
 5  Lupus (SLE)/Soriatic Arthritis Hypoglycimia like symptoms, gas but the absolute best side effect yet? I HAVE MY LIFE BACK!!!! I can be a mom and a wife again because I can get off the couch now! Yesterday I even went bowling with my family! I'd rather go blind than ever be without this medication again. It has given me my life back when I had just about given up hope of ever being well again. Thanks to this wonderful drug, my kids will look back on their childhood and remember all the cool things mom did with them instead of all the things they had to do for mom because mom couldn't get off the couch anymore. M 29 2 months
10/14/2004
 5  RA diagnosis None Started at 200 mg 2x's/day; went to 1/day. Eye check ups every 6 months. Been taking for 4 years. M 53 4 years
4/22/2002
 5  rheumatoid arthritis Bit mushy thinking M 55 3 years
12/6/2007
 5  Immune Disease(s) none for 5 years It DID help me greatly for 5 years. But about 6 months ago started having severe muscle fatigue. NO ONE suspected it was Plaquenil causing skeletal muscle neuromyopathy and abnormal nerve conduction. I was literally 10 minutes away from starting chemo again when my doctor checked the side effects of this drug. Take the drug but make sure all your med. professionals have a copy of Clinical Pharmacology on their desk. M 52 6 years
11/17/2007
 5  RA (stills disease?) nausia and gas I was extreemly ill for three years, I was completely debilitated and the doctors did not know exactly why-althought they all agreed it was autoimmune RA JRA Stills Adison... Anyway I had extreem fatigue, daily fevers, hair loss, swollen joints. I was put on sulindac (this is the best NSAID I ever found and I tried all of them including the COXX 2s) and then six months later plaquenil. The plaquenil got rid of the fevers, morning stiffness, fatique and hair loss. I felt human again. Eventually the disease was in a remission deep enough that the plaquenil side effects ( just GI symptoms) were worse then the disease. I stayed in partial remission for seven years. I had a bad flare last month and the first thing I did was ask to be put back on Plaquenil. M 36 3 days
12/3/2007
 5  Still's Disease Minor bloating and gas. It has workded wonders for me! Before being diagnosed by a Rheumatologist and being put on the drug, I was in and out of the hospital. Since I started Plaquenil the diesease has been held at bay. Thank God M 39 3 years
2/22/2008
Email
 5  MCTD Itchy Skin. A little more forgetful. This medication changed my life. It took a few months to start working, but when it did, everything just got better. My joint pain and rashes slowly went away, and haven't come back. I sometimes get rashes and joint pain every now and then, but very mild cases of them. I am so thankful for this drug. M 24 2 years
2/22/2008
 5  Sjogrens flatulence; I am more aware of the neuropathy in my hands and feet I am a physician. I thought it would take weeks to have any benefit. Within hrs my fatigue was gone and the fogginess in my head had cleared. I thought it was a placebo effect but after reading the other comments, I guess it is real. So far it has given me my life back M 56 2 days
1/15/2009
 5  RA occasional bouts of diarrhea and gas It has really worked for me. I took myself off the medicine once, thinking I might not really have RA since it was totally in remission. And then I had an unbelievable flare. I hurt so much I became depressed, I could barely work. I have not done that again. I'm a believer. M 64 6 years
6/23/2008
 5  RA Maybe diarrhea In the very short time I have been on it, I have improved about 95%. I want to comment about itchiness: I've noticed others attributing this to plaquenil. Well, two months ago, before I started on the plaquenil, I had one night where both my underarms and the palms of both hands were unbelieveably itchy. But there was no rash and the skin was unbroken, and the next day the itch was gone. Maybe it's not the plaquenil, but, for some people maybe it is. M 74 3 weeks
8/7/2008
 5  Antiphospholipid Syndrome and Lupus Absolutely none Took three months to start working, but reduction of swelling and therefore pain, and the reduction of Clotting events (Strokes and Transient Ischemic Attacks (TIA's or mini-strokes)) has been tremendous M 59 7 years
7/5/2009
 4  SLE? Stomach upset, dizzy at times. Its hard sometimes to distinguish what may be a result of the meds and what is caused by other factors......diet, exercise, age, etc. Had skin issue 10 yrs ago. Blood markers(low white cells and elevated ANA) were consistent with SLE. Have been reluctantly taking Plaquenil now for 10 yrs. Even though my blood results are now good Doc says "better to take it and keep the SLE in check than to try to control it with steroids if it flares...."Plaquenil is safer than aspirin". I REALLY DISLIKE this style of doctoring of you must take meds out of FEAR. M 58 5 years
200 1X day
10/13/2014
Email
 4  RA I seem to sweat more than usual. A change in dream patterns. Irritable at times, as well as nervous and anxious. The RA symtoms have greatly dimished at this point and doctor says I may reduce from 400mg to 200mg soon. P.S. he also says the (irritable at times, as well as nervous and anxious)should not be a typical side effect. Maybe some of us are not typical as I read where several of you had the same side effects. M 50 1.5 years
6/19/2008
 4  RA Itching skin, like a rash but with no obvious marks or redness. Mostly on the legs,feet and arms M 43 7 years
2/5/2009
  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

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