PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Sjrogrens 0 days
8/6/2017
 4  I have primary Sjogren's When I first started I had nausea if I took the Plaq. on an empty stomach (now I take it with food) and some diarrhea, but that has passed. This has been an incredible drug for me: before plaquenil I could barely walk 3 blocks without severe pain, had to rest every hour on the hour and did not have enough energy to do F 5 months
12/29/2004
Email
 3  Inflammatory arthritis A little nausea for the first week; then none This medication worked somewhat, but not enough. It helped get me back on my feet after a horrendous bout of arthritis, but it did not do enough. Now, I'm starting Enbrel. I'm really sorry it didn't work better, because it had absolutely no side effects after the first week. F 3 months
10/22/2004
 2  SLE Gas, bloating, starting hair loss & severe itching. Gas & bloating started by 2 days. Hair loss, 1 week. Itching started 2 nights ago. Can't see a red rash everwhere that itches but, do feel tinys bumps. Some places are red but, that may be from scratching. I can't take Benadryl (major interaction with Amitriptyline; I take that for severe insomnia). I stopped taking it yesterday (200mg twice a day). Still have itching; maybe not quite so bad today. F 2 weeks
1/27/2009
 2  Seronegative Rheumatoid Arthritis Mild diarrhea only for the first few days. Other than that no stomach ache if taken with food. It may have started helping on or around the fourth month because foot pain eased and it was a little easier to get out of bed, I did have some of the worst flairs ever on it. Started getting flu symptoms, fevers, swollen glands. Had extreme dizziness and extreme hair loss. I don't know if the hair loss was from the BCP that I started around the same time or the Plaquenil, but it is copius hair loss. Very depressing. I quit the med because I didn't see a lot of improvement and I wanted to get rid of the awful dizziness and hair loss. If the hair loss continues then it is probably the pill. Plaquenil works for a lot of people, I will restart it if the hair loss is due to the pill. F 4 months
200 mg 1X day
5/24/2013
Email
 2  RA Stomach cramping and frequent urination that leaves an annoying feeling after urinating with not being able to completely empty bladder. This happened during the day, but more so during the night. F
400mg 2X day
9/5/2014
 1  Lupus like symptoms After taking Plaquenil for 30 days, I developed a severe rash on chest, arms, legs, back. Dr. advised to stop taking Plaquenil, and to clear up rash, take 20mg Prednisone twice daily for 4 days and to also take 4mg Cyproheptadine three times daily for five days. It worked! 30 days
12/8/2008
 1  Mixed connective tissue disease After 2 1/2 weeks on Plaquenil I developed flu-like symptoms, fever, could'nt get out of bed for days and a rash over my entire body. Doctor confirmed an allergy to Plaquenil and put me on a two week course of prednisone. I am so itchy I'm ready to jump out my skin. They said the rash will go away in two weeks. Don't know what I'm going to do next medication wise. 3 weeks
1/26/2009
 1  Lyme THINNING HAIR!!! After being warned of eye issues, I took this drug and hoped for the best. It didn't help my symptoms and coincidence or not, my beautiful hair started falling out and has thinned. It's also not cheap if you don't have Rx coverage! F 6 days
11/5/2002
 1  spondylitis Pounding in temple, headache, increased heart rate, irregular beats. I didn't feel any improvement but I know it can take months to work. The pounding in my temple and chest was bad. I just went off it for four days and will try again. M 11 1 months
5/16/2004
Email
 5  Lupus SLE Loss of hair, dizziness, and stomach aches I have only been on this medicine for two years now and it has really helped out with my lupus conditions. But right in the beginning it thinned out my hair a ton which stinks but it's better then my liver enzymes elevating!! When I forget to take it one day and then take my regular dosage the next day it gives me a really bad stomach ache and dizziness to the point of fainting. But that's only occassionaly when I forget it. All in all though it really has relieved the stress of my lupus getting worse with little side effects. I rather not have to take a drug the rest of my life though:( F 15 2 years
200 2X day
6/17/2010
 3  Rheumatoid Arthritis Upset stomach, headaches, running nose, swelling of joints, extremely sensitive eyes. I haven't been using Plaquenil for long, so I guess it hasn't had enough time to start working properly, but I'm not sure whether I want to keep taking it or not, due to all the side effects, I'm not sure if it's really worth it? F 16
1/28/2008
 2  JRA I started out with horrible stomach pain, I don't get hungry anymore, I get strange high pitched noises in my ear kind of like the weather alerts on TV, and strange dreams, I never remembered my dreams before starting it, and if woken up I'll still be dreaming and talking to people in it sometimes I'll walk around. Now my hands and feet are starting to peel, I am on a lot of other medications for my Intercrainal Hypertension and my doctor just keeps telling me its from taking four other meds. All of the side effects are getting worse. F 16 2 months
6/17/2009
 4  Lupus and sjogren's Itching in hands and feet when first started taking it, hair loss after about 3 months of taking it, headaches when I forget to take it I take the generic brand and it has really helped me with all my symptoms of lupus and sjogren's!! In the beginning my hands and feet itches to the point where I would start crying and couldn't sleep but that went away after the first couple of weeks and inhale never had that problem again. My hair was thinning for a couple of months but has now stopped but my hair is a lot thinner :( and when I forget to take it I can tell because I will start to not feel good! Overall this drug saved my life and gives me to do whatever I want with all my symptoms of my diseases under control !! I would recommend it, thank you plaquenil for letting me be just another teenager like all my friends!! F 17 10 months
300 mg 1X day
1/20/2011
 2  sarcoidosis i am so itchy all over, blotchy red rash on feet and hands, red bumps have appeared on both arms and on back. F 17 2 months
10/22/2004
 1  JRS uncontrollable muscle twitches that have remained for years, permanent nerve damage I went to the ER with uncontrollable muscle movements a couple years ago. My doctor said it was the plaquenil. My fingers still twitch, but not as badly since I stopped the medicine. I had also had caffiene during the inital twitching episode. F 17
2/6/2009
 1  Sjogren's I am writing this for my 17 year old son who took Plaquenil for Sjogren's. He experienced severe depression, anger, anxiety while on this medication. No longer will be taking Plaquenil. M 17 21 days
12/26/2009
 5  Connective Tissue Disease/Lupus None I had such bad pain I couldn't walk without my bones cracking. I take plaquenil everyday 200mg. It has truely improved my life. Still pain bothers me every now and then, but I wouldn't be able to go on without this medication. It has helped me ALOT. If I miss taking the pill for a few days, I notice a big difference. F 18
3/23/2009
 5  SLE no real side effects I take 200 mg twice a day and this has been a miracle for me. I love it, however recently my doctor changed it to 200 mg once a day and I have started to get headaches and night sweats again. Has anyone else had this experience? F 19 1 years
5/21/2005
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 4  Rheumatoid Arthritis 20 pound weight loss( i am 5'6" and was 130 and am now 110, lack of appetite( obviously..), nightmares, random nausea and headaches While it has caused a few issues, the overall benefits have outweighed them and I have definitely had a lot less aching, swelling and fatigue. F 19 6 months
400 1X day
6/2/2010
  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

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