PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Dermatomyositis/ connective tissue After taking plaquenil about a week, I started itching all over my entire body. Noticed a severe rash. My skin felt hot to the touch. Went to dermatomyositis who said stop taking it and did a biopsy to confirm I was allergic to the drug. Nine days later and not any better. Back to dr who said it may take weeks to get out of my system. I'm rotating ice packs throughout my body. This is the worse nightmare of my life. Unbearable itching from my head to top of my legs keeping me awake all night... please let this end soon. F 81 8 days
200
6/24/2020
Email
 4  polymyalgia rhuematica I have been taking 2--200mg. tablets a day for 6 weeks (plaquenil) I am feeling much better, my muscles are not so stiff & painful. No side effects so far. F 80 6 weeks
12/10/2005
 2  Inflammation from osteoartritis severe Tachycardia 4 to six times daily, itching rash. Trembling inside my body you could not tell by looking at me I could just feel it,I felt that my hair was falling out two. It did completely take care of my severe feet and leg burning from day one or two really liked it for reason.that was just too many side effects talked with my pharmicist and he suggested I quit taking it until I talked to my Rheumotoligist. F 80 10 days
100mgppl
2/20/2017
 1  lupus cardiomyopathy after taking plaquenil for 12 years i find out i do not have lupus.my dr. at the Mayo clinic took me off plaquenil. I now have what is called a hard heart,the blood is not pumped out like it should causing irregular heart beats with water build up around the heart and lungs. My comment is be sure of your diagnosis. Do you have lupus? F 78 12 years
2/11/2004
 5  RA Interesting dreams but occasionally violent. (I am a very calm person and have been told I have nice humorous personality.) Strong metallic taste. Urine has metallic odor. Increased sensitivity to light, taste, smell. Minor change of hair color from light gray to reddish-brown. This is a fantastic drug and has allowed me to manage my RA with minimal flair-ups. I was originally treated with prednisone. After six months I was given both the prednisone and 200mg x2 daily for about 16 months until I had sufficient plaquenil onboard. For the past four months I have used only the plaquenil and tolerate it well. This has been a perfect drug for me. I had very debilitated and severe pain in my hands, wrists, shoulders, upper arms and hips which came on very suddenly at age 75. I had difficulty sleeping more than an hour and then usually only in a chair. Walking, showering, and any exercise was very painful. Today I walk and do moderate exercise, build furniture, work in the garden and just about anything I like. M 77 2 years
200 mg 2X day
3/13/2010
Email
 2  Polyarthritis Eyes a little dimmer when reading - I have spoken to at least 3 Dr/ Specialists and have had Ross River fever some 20years ago - I took about 18 months to recover from ROss River fever ( which according to the world "you never ever really recover" as it is an immune response problem and I was treated with Feldene etc over 2-3 years - the Drs told me that I would have recurring "bouts of hectic pain" in the future accompanied by Malarial type reaction about twice a year - tiredness , exhaustion, and stiffness followed but I rowed my machine daily , ate good healthy food , few red wines and became pretty fit & well again / My previously damaged joints like toes ( football) and hands -fingers / wrists ( boxing etc ) have now erupted into a very painful state whicb varies in intensity day to day .... The Gurus label it - Polyarthritis - and its just 'wear & tear' and have suggested Methotrexate as a final solution but introduced me to every other pain relief like Diclofenac - Ibuprofen - Celloxocib - Paracetamol - and all of these in various generic presentations ? I sleep at night after Panadol x 2 but usually wake twice or so on the night with soreness and by 6am I am feeling exhausted - I am a reasonably robust person , I walk & swim comfortably but I am generally declining in my self - The pain ha at times in my wrists agonizing and I really don't know how to control or maintain at 76 4 weeks
20mg 2X day
9/27/2020
Email
 1  active rheumatoid arthritis Sore throat, led to not eating much because of swallowing, nausea, food didnt want to stay down. Day of hospitilisation, diahorrea, vomiting, weakness , dehydration. This is written on behalf of my mother. Have had the arthritis for many years, told it active in October 2006. Saw speciialist Nov 2006. Had notice lumps in fingers starting to disappear in December 2006 but could of been result of other new medication at the same time. Admitted to emergency January 2007, because of weakness and diahorrea. Very dehydrated. Tests completed - small stomach ulcers, and severe Thrush up through chest and throat. Symptons only occurred in a matter of days, sore throat was checked by doctor prior, thought to be inflamed. Severe symptons only come on within two days and led to my death within a week. Was told amount of dosage was too high for this age, 200 mg.( 2 tablets) Dosage recommended for 25 yr old. F 76 8 weeks
2/5/2007
Email
 1  active rheumatoid arthritis Sore throat, led to not eating much because of swallowing, nausea, food didnt want to stay down. Day of hospitilisation, diahorrea, vomiting, weakness , dehydration. This is written on behalf of my mother. Have had the arthritis for many years, told it active in October 2006. Saw speciialist Nov 2006. Had notice lumps in fingers starting to disappear in December 2006 but could of been result of other new medication at the same time. Admitted to emergency January 2007, because of weakness and diahorrea. Very dehydrated. Tests completed - small stomach ulcers, and severe Thrush up through chest and throat. Symptons only occurred in a matter of days, sore throat was checked by doctor prior, thought to be inflamed. Severe symptons only come on within two days and led to my death within a week. Was told amount of dosage was too high for this age, 200 mg.( 2 tablets) Dosage recommended for 25 yr old. F 76 8 weeks
2/5/2007
Email
 5  RA Maybe diarrhea In the very short time I have been on it, I have improved about 95%. I want to comment about itchiness: I've noticed others attributing this to plaquenil. Well, two months ago, before I started on the plaquenil, I had one night where both my underarms and the palms of both hands were unbelieveably itchy. But there was no rash and the skin was unbroken, and the next day the itch was gone. Maybe it's not the plaquenil, but, for some people maybe it is. M 74 3 weeks
8/7/2008
 1  I was on plaquenil for Raynauds. I took Plaquenil for 10 years. I was not told about the eye problems it could cause. I have very severe eye problems--can't drive at night--very hard to read--have been to several Ophtamoligists and eye specialists here and abroad...nothing can be done. There is severe damage to both eyes caused by this drug.I am now on Tracleer which is helping Raynauds much better--and can cause no further damage to my eyesight. If you use it--please have your eyes checked regularly by a specialist. F 74 10 years
10/18/2007
 2  For RA - pseudo gout itching! On arms, legs, back, waist. Loss of hair, and thinning of skin, slow weight loss of 15 lbs. I was put on Plaq. for a high RA Factor. (400) and was diagnosed as having RA because of one swollen joint. After a year of plaq. I saw another Rheumatologist at UCLA that emphatically told me I did not have RA but CPPD -- calcium pyrophosphate deposition disease -- also called pseudo gout that can make a joint flare. But I have stayed on plaq because both doctors said it might help my joints, in spite of the itching while my MD here in No Cal and my UCLA MD fight over my DX. So will this hurt me? I really don't like the side effects but don't want another flare up...My RA Factor is creeping up again...Is this working? 72 2 years
1/9/2010
Email
 2  RA I have always taken this drug with food and have never experienced any side effects. About a year ago, I was diagnosed with both Osteoarthritis and Rheumatoid Arthritis. At first I was put on 12.5 mg. of Methotrexate per week but didn't really notice any relief. Plaquenel was added about 6 months ago, and although I haven't experienced any negative side effects, I also have not had any joint relief. I saw my Rheumatologist yesterday, and he now thinks I am only dealing with OA...Not RA. I feel like I am living from appointment to appointment and have e-mailed my doctor today requesting a referral for a second opinion. I definitely want to get off Plaquenel ASAP but don't know if I can just "quit" or if "tapering" is better. I would love to get some input from somebody who has gone through this. Many thanks...Nancy F 70 6 months
200 mg 1X day
10/3/2012
 3  LupusI I worry about the side effects it can possibly have on your eyes F 69
8/23/2003
 3  LupusI Mostly discororation of the lower arms some on the hands< I have never come off the Plaquenil since I first started taking it. I was wondering about the real long term effect. I worry about the side effects it can possibly have on your eyes F 69
8/23/2003
 1  ra Agitation,stomach cramps,brainfog,itchiness,fatigued,overall joint pain worst than I had previously felt. Not myself,in there but no input? I was using generic brand until 3 days ago. Food tastes lousy lost weight.I quit cold turkey is that wise now I feel good.I can think& discern.Please answer the question and what is yhe connection between hydroxychloroquine and summer and winter. Oh!I forgot the sweats. side effects need to be made aware of not trial and error of individuals! F 69 2 months
200mg dail
3/12/2016
 4  Sjogren's Syndrome Started with name brand, then switched to generic. After several refills, I noticed that I was feeling like I wasn't taking any all at. My rheumatologist said that some patients do not do well on the generic, so she put me back on the name brand. I've been taking Plaquenil for 16 years, and except for the generic not being effective for me, I've had no problems. If I forget to take it, I can definitely feel it! I've always gone in for twice-yearly eye exams and so far, I'm doing very well and even my ophthalmologist is very surprised. Make sure your ophthalmologist does the "vision field" test every year as problems with peripheral vision is the most likely sign of damage from Plaquenil. F 68 16 years
200 MG 2X day
5/3/2013
Email
 4  Undifferentiated interconnective di None that I remember when first taking but for approx. 8 years now I emit a BAD odour from FLATULENCE. Not the explosive kind, but seems like a slow leakage constantly, It is isolating and causes me to cancel many social functions. It was only in reading this site that I could see it may be the Plaquenil. Luckily it only became a problem towards the end of my working life. I am thankful for the way it reduced my pain & stiffness and gave me back my mobility and energy (if I also balance my life properly). Just want to know HOW to get rid of the flatulence side effect - and does Plaquenil cause a yeast overwgrowth? F 68 18 years
400mg 1X day
9/24/2011
Email
 2  connective tissue disorder SS Nausea, anoreaxia, stomach trouble, gas. Feverish burning feeling, red patches on the face peeling,swollen face. General feeling of being more unwell then before. Worse of all, sudden severe migraines which were previously well controlled by prevenative. I take it three times a week only 200mg This is mu second try aftre severe reactions few month ago after only second dose. I take is 3 times a week 200mg F 68 2 weeks
8/5/2006
 1  Sjogren's & RA Terrible drug. Increase in all-over horrible pain, more eye pain, pain in face, increase in weakness, terrible dizziness, emotional, wanted to cry, agitated, , more balance issues. Stopped taking it and can't wait for it to clear system. Will try taking anti-inflamatories although they cause me colon issues, they can't be as bad as this nasty drug. F 68 2 months
200 1X day
7/14/2016
 5  SLE Didn't have any at all.Have been on it for 6 years. It has helped me tremendously,especially in the area of joint pains. F 67 6 days
10/27/2005
  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

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