ENDEP Reviews (AMITRIPTYLINE HYDROCHLORIDE)

Average Rating: 3.3 (35 Ratings)

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 ANTIDEPRESSANTS

 Type: Brand name discontinued; available as generic

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENDEPCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  insomnia heartburn constipation numb arms legs helps my sleep. F 80 0 days
10mg 1X day
7/17/2023
 1  Depression, anxiety, insomnia Fatigue Inability to wake up Foggy head Feel like shit all around Do not take this drug. It will mess with your head in a major way. I am quitting it after only two days because it is AWFUL. F 28 2 days
25mg
7/29/2015
 1   Can't sleep up from 1am now3.30 urinay retention weakness arms legs hands dry mth trembling hands unsteady on feet feel fluid in legs also have health problems fmd so not sure about this so called happy pill felt my brain closed off ? Not for me Did calm down my mind first few hrs but wide awake 1.am now1/4 to 4am felt sick legs wobbly bladderdecrease in frequency out put I don't like it F 64 1 days
1/2 10mg
3/2/2015
 1  leg pain severe dizzyness, dry mouth, diaahrrea M 79 2 days
50 1X day
11/14/2014
 1  insomnia and depression Dry mouth, waking during night, excess body heat, drowsy next day, no motivation, weight gain, bad reflux and heart burn, -going off it asap F 49 2 weeks
75mg
5/21/2013
 2  Back pain and sleep Worked for sleep until 3 days ago diarrhoea, phlegm build up in throat causing a cough and dry reaching, vision very blurry panic attacks and suicide thoughts F 63 5 months
10 mg 1X day
1/2/2021
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 2  Transformed Migraine Drowsiness that continues into the next day and this is with only taking half a tablet (12.5mg) which my GP said to start with but even with this dosage the drowsy/groggy feeling is unpleasant. I have been on this for 5 days with no improvements so far for my condition of chronic daily headache (transformed migraine) and unrefreshing sleep/apathy (mild depression). Will persist for a bit longer and hopethe side effecst subsides and there will be improvement M 52 5 days
12.5 1X day
12/12/2012
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 2  anxiety, insomnia From the git go, this product 'zonked' me out big time, to the point I stopped taking it after only 1 month. I had been taking Zoloft (which worked great), but was prescribed Endep instead when I developed side effects (muscle twitches) after a few months. My doctor suggested I take half a tablet of Endep every night, but then the dosage was too low and had no effect. I suppose the full 25mg dose may have worked, but I was so doped up I felt out of it anyway so I can't really say if it was effective or not. I don't recommend this product. M 58 1 months
25mg 1X day
3/4/2011
 3  Chronic back pain & insomnia Brain fog, lethargy and mild anxiety Dr recommend Endep at 10mg once daily to (1) help with managing neuropathic pain from chronic back problems and associated rehab activity, and (2) for long term insomnia from back pain. Found the medication effective in reducing severity of nerve pain and helped with getting to sleep and duration of sleep. However, the day after effects are significant. Low mood, anxiety and bouts of extreme tiredness have become daily issues. Hoping these reduce as I need to continue taking this medication while I go through intensive rehabilitation for my back. M 48 7 days
10MG 1X day
10/25/2020
 3  Sleep and depression I take 150 mg Seroquel, 10 mg Endep, 75mg Lyrica. They have worked for the last 3 months but now its been 2 days and nights of no sleep at all. My legs feel like they are going to give out and they are sore. Also feeling very sick on the stomach. I also have a Duralgesic 25mg patch and Effexor 150 mg. Has worked for at least 3 months with great results ( sleeping all night and depression not as bad. F 45 3 months
10mg
12/8/2017
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 3  Chronic back pain Difficulty waking up in the morning, but it improved within 2 weeks. It's still hard to wake up and be coherent but I can get up mostly when I need to. Dry mouth, improved with time. Weight gain, becoming a problem. I can function because of this drug. Previously I would need codeine just to get through a shift at work, and sometimes had days off because it was so bad. I'm not pain free but I can manage each day a lot better now. F 30 1 years
10mg 1X day
11/4/2015
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 3  Recurring headaches Very drowsy about 30 minutes after taking 2 x 10mg tablets. Sleep well. Feel lightheaded during the day but headaches started to improve (still there, but less severe) from day 5. M 30 6 days
10mg x 2 1X day
1/28/2015
 3  Fibromyalgia Diarhea, severe lower back pain, dry mouth and thirst, I am getting longer sleep, F 54
20mg 1X day
10/4/2014
 3  Pain and depression Still depressed F 54 5 months
2/22/2013
 3  neuropathic pain and insomnia Dry mouth, sour taste in mouth, thirsty, drowsy, no libido and feeling low. I recomend it's use if you suffer from pain and cannot sleep but since it's also used for depression I'm not sure if it will affect your mood if used for a long time I also take 50mg of zoloft but still feel depressed don't know if any of these drugs really work once your body gets used it. M 45 8 years
11/27/2008
 3  lupus pain and lack of sleep Endep did help with my muslce and joint pain and it was really good as a sleeping aid ( able to come of sleeping tabs 'stilnox' after 2 yrs of use), but I did have slight weight gain and I needed something stronger as an antidepressant as I was only on 25mg. F 32 5 months
8/7/2005
 4  Back pain; anxiety Dry mouth; no libido; low mood; dizziness; trembling hands at times, brain fog; memory issues; tiredness next day; My Doctor said it was a wonder pill, and everyone should be on a small dose a little blue pill as she called it. Well after 2 years I am sick of the brain fog and memory issues. I went back to study and it really affected me. I am off it now for last 4 days. Pain came back so bad by Day 2 I was going to go back on, However, am back on pain meds anti inflammatory Eg disprin occasionally, helps relax muscles, Panadol, voltaren gel, See how I go, Read someone's post they only take it 3 or 4 times a week, so might try that F 62 2 years
10 1X day
11/1/2022
 4  Anxiety & sleep At first I slept all night but it started having no effect after 2 months. I was waking up feeling a bit dazed but it goes away in a few hours and I feel great after that. All I can suggest is start on a low dose and raise it a week at a time. Side effects do go away in a month or so M 57 4 months
25 1X day
8/30/2022
 4  Depression Dry mouth The best anti depressant I’ve ever taken and I have been on anti depressants since I was 27. SSRI’s only caused insomnia and loss of libido. I would never touch SSRI’s. Horrible. I gave Endep a score of 4 because the only side effect was an extremely dry mouth. It also made me sleep as soon as hit the pillow. No problems with sex drive or orgasms. F 61 2 days
150 1X day
9/6/2020
 4  Lacking quality sleep,only 4hr/h/n None Take one tablet 3 or 4 nights a week, for 7 hrs+ sleep a night. Wake up feeling good for work. M 57 3 months
10mg 1X AN
12/25/2016
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