AMITRIPTYLINE HCL Reviews (AMITRIPTYLINE HYDROCHLORIDE)

Average Rating: 3.0 (64 Ratings)

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 ANTIDEPRESSANTS MIGRAINE HEADACHES

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AMITRIPTYLINE HCL  (AMITRIPTYLINE HYDROCHLORIDE):  This medication is used to treat mental/mood problems such as depression. It may help improve mood and feelings of well-being, relieve anxiety and tension, help you sleep better, and increase your energy level. This medication belongs to a class of medications called tricyclic antidepressants. It works by affecting the balance of certain natural chemicals (neurotransmitters such as serotonin) in the brain.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on AMITRIPTYLINE HCL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR AMITRIPTYLINE HCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Headaches, eye pain, insomnia Fast weight gain, pruney skin on fingers, dizziness, drowsiness, makes it difficult to get out of bed, gotta sleep it off, unable to function and get about the day when always dizzy and drowsy from this medication. Helped somewhat with headaches, eye pain, and insomnia. But side effects were not worth it. F 45
1X day
8/2/2023
 1  Pain Audio hallucinations. Extremely drowsy, easily angered. This is a horrible drug in American healthcare is substandard the best. M 59 0 days
1X day
2/23/2023
 5  Panic attack , anxiety Good sleep F 45 6 months
25 1X day
12/20/2022
 2  Pain, Anxiety, Antihistamine Pure exhaustion, blurred vision, brain fog, irritability. While this medication was helpful for my anxiety, pain somewhat and histamine issues, I had to give it up. Sleeping 12-14 hours a night and still exhausted during the day. My anxiety eased up some but it's hard to say if that's because the drug was effective or because I was SO tired I just didn't care much about anything. I lean strongly on the natural side of dealing with health issues and this was one of my first tries at using a pharmaceutical. I have a natural stack that I've been using for years but decided to try this route cause it's dirt cheap compared to what I spend. I'll be going back to using Inositol, Quercetin, l-theanine, CBD, and B12. More effective and zero side effects. M 46 3 months
10 MG 1X day
4/5/2022
Email
 3  Insomnia Depression I Sleep like the dead but still drugged in the morning. The dreams are many and vivid. my depression has lightened a little so far so I'll stay with it longer and see where this goes. I'll try to adjust what time of day I take it because before bed leaves me hung over in the morning, but I sleep solid. if you already sleep well this drug might be a problem for you. I cant imagine upping the dosage on this. M 58 14 days
10 MG 1X day
1/23/2022
Email
 1  fibromyalgia severe urinary retention, could not urinate....stopped cold turkey and immediately the retention problem ceased. I refuse to take a drug to stop another drugs side effects.... How can FDA stop elavil due to side effect problem but then release it under generic name (amitriptylilne) with the same side effects??? F 81 60 days
20 1X O
1/16/2022
Email
 5  Anxiety, chronic tmj pain, insomni Working well on my anxiety and sleep. Never slept so good since I was a child. Don't wake up groggy. No brain fog. It dosen't make very sleepy but once I am asleep I sleep more sound than ever. It has also helped my chronic TMD/TMJ pain. I might seek a bit higher dose soon to see if it would help more with the pain. I take this in addition to Lexapro and Ambien PRN. I took 10 mg Ambien for years but now 5mg seems to work fine since starting amitriptyline. Very happy with this medication so far. No real side effects thank goodness. Be well! M 49 4 months
10mg 1X day
11/5/2021
 5  Anxiety and Panic Some physical side effects. The usual: Dry mouth, constipation etc. The first drug that I have responded well to and tolerated. I think SSRI medications are seriously overrated and overused! M 24 8 weeks
100mg 2X day
11/24/2020
 1  Nerve pain I was like a zombie during the day, made me moody and psychotic, caused anxiety and made my pain worse. I was only taking it for approximately 3 weeks and I still had side effects after a week F 41 3 weeks
5mg 1X day
9/19/2020
 1  IBS Prescribed for IBS-d as a neuromodulator to stop diarrhea. WORSENED the diarrhea and cramping. More MD's need to know the paradoxical effects of these drugs -- look at the studies - half the subjects drop out. F 69 3 days
10 mg 1X day
9/11/2020
 4  Neuropathy dry mouth sleepy and dizzy just hope I don't gain weight from this F 47 6 days
25mg 1X day
7/6/2020
Email
 3  CFS, Insomnia, IBS, Panic disorder Very hungover upon waking up everyday, extreme dry mouth, weight gain, tachycardia, postural hypotension Amitriptyline worked great putting me to sleep for the first 2 years, but by the 3rd year it's effect was extremely delayed. Waking up was very difficult and couldn't function for first 3 hours after waking. Weak and dizzy most days, but no daytime sleepiness. It controls anxiety well and helped IBS about 50%. Didn't seem to do much for my CFS pain. 15 lb weight gain was gradual over 3 year period. F 42 3 years
25mg
5/1/2020
 3  Insomnia Works for 3AM awakening and I go back to sleep. Without I am awake for 1-2 hours. Sometimes I split pill in half. Sometimes I feel tired in the morning but not terrible. M 72 12 years
10mg
2/12/2020
Email
 5  Pain Dry mouth and sedative effects F 57 5 years
150 1X day
12/13/2019
 3  CFS, anorexia, insomnia Weight gain, allergy suppression, fatigue, depression, electrolyte imbalance This worked for me at first but I had to start low, didn't gain too much weight but it no longer helped with insomnia after I came off it. Had hurt my back and the amitriptyline didn't cover the pain anymore. Went crazy with pain treatments which made my body lose more nutrients. Lead to a total loss of electrolytes, weight loss, depression, allergies came back. Use a short while if you have to but consider healthy alternatives with diet and exercise, cognitive therapy if you need it first. Avoid too many additional drugs you can get dehydrated taking this. F 63 15 years
100
3/1/2019
 3  Chronic headaches Slept a lot (10 hours a night), brain fog, weight gain Be very careful COMING OFF of this medication. I was only taking 50 mg a day (at night), and tapered by 10 mg per month over five months (i.e., took 40 mg/day during the first taper month, 30 mg/day during the second taper month, etc.). I was very sick for about two months while tapering and thought something was seriously wrong with me -- I went to my PCP and had a full (expensive) blood work-up which was normal. The withdrawal symptoms were a general sense of malaise -- muscle aches, slight fever, feeling like I had the flu every day for two months. My neurologist completely invalidated that this was amitriptyline withdrawal, claiming my dosage was too low to cause such withdrawal symptoms. He was clueless! I went to the primary literature about "cholinergic rebound" and apparently it's very common (Google "cholinergic rebound syndrome"). Another consideration is that this medication, along with other "strong anticholinergics," has been associated with significantly higher risk for dementia, even in middle-aged patents -- see Gray et al. 2015, Cumulative Use of Strong Anticholinergics and Incident Dementia: A Prospective Cohort Study, JAMA Internal Medicine (available online). This paper by Gray et al. is what made me decide to go off the medicine, but going off it was hell. Be careful! F 47 1.5 years
50 mg 1X day
6/10/2017
 4  Chest pain associated with anxiety It helped me immediately...however the "hazey" feeling in the morning took some adjusting. No weight gain..although I have had some minor heart palpitations. F 68 1 years
10mg
3/25/2017
 2  Sciatica, back pain and leg pain When I first started taking amitryptaline it would immediately put me into a deep sleep after about 30 minutes of taking it, I would be in the deepest sleep and be a complete zombie the day after. It gave me an incredibly dry mouth and very dry eyes. These side effects disappeared after a couple of months and I actually started to enjoy getting a good nights sleep! The most noticable physical side effect I still have is that I can no longer drive at night as it has effected my sight quite badly - the lights all blur into one and I can't see anything, this has never been a problem for me before. In honesty I'm not sure if it improved my sciatic pain or whether it just naturally improved itself. I do know that it let me completely relax during the night, maybe that was why it helped me. I initially started on 20mg and reduced myself to 10mg about a year ago as my pain has virtually gone. About 3 months ago I had a complete mental breakdown for absolutely no reason - I have a great life a F 24 2 years
10/20mg 1X day
3/25/2017
Email
 4  For depression None Do endep still work after taking it for around 20 years F 70 10 years
75mg
3/10/2017
Email
 1  Chronic intractable migraine I have suffered from severe migraine for 28 years and have been on just about every med out there. When my neurologist prescribed this I had an extremely dry mouth and was very forgetful. I asked about it and he said it should go away. It was so bad I felt like I could hardly function. I would forget what I was talking about mid sentence . Then it finally did get better. Not all the way better, but better. However my biggest issue was weight gain. I have been within 5 pounds of the same weight for 20+ years. Even after having a child, I returned to the same weight. This caused me to go from 120 to 143!!!!! My eating was really no different. My neurologist told me it can totally slow your metabolism. What?!?! I should have been told that!! I told him I was done and he weaned me off it. It's been 1.5 years now and I am still struggling to get that weight off and waiting for my metabolism to go back to "normal." I am just furious about it as I didn't "earn" my weight gain. As if 28 years with debilitating migraine want bad enough....now I gained a good amount of weight. UGH!!! My advice? DON'T take this! Too many other meds out there! F 43 6 months
100mg
1/11/2017
  

AMITRIPTYLINE HCL  (AMITRIPTYLINE HYDROCHLORIDE):  This medication is used to treat mental/mood problems such as depression. It may help improve mood and feelings of well-being, relieve anxiety and tension, help you sleep better, and increase your energy level. This medication belongs to a class of medications called tricyclic antidepressants. It works by affecting the balance of certain natural chemicals (neurotransmitters such as serotonin) in the brain.    (Sources: U.S. Centers for Medicare Services, FDA)

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