IMIPRAMINE HYDROCHLORIDE Reviews (IMIPRAMINE HYDROCHLORIDE)Average Rating: 3.5 (106 Ratings)Filter ResultsCompare IMIPRAMINE HYDROCHLORIDE with similar:
Type: Rx Drug
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Results are sorted by length of time drug was taken longest to shortest. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on IMIPRAMINE HYDROCHLORIDE: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR IMIPRAMINE HYDR | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 4 | panic attacks and agoraphobia | initially dry mouth, hard stools, some tremors in one arm. chew gum or suck on a candy with dry mouth, and stool softener works well when needed. just live with the tremor. | my father took imipramine before me for 30+ years, and i have taken it for 33 years. my dad went off it due to his skin getting very dark after years of use. his skin lightened after going off the medication and switching to zoloft. i have used the meds for panic disorder and agoraphobia. i have consulted with psychiatrists over the years to determine if there is a better med. all the docs have said stick with what works, and i am doing so. | M | 63 | 33 years 150 1X day | 9/19/2010 | 5 | Anxiety in response to panic | Side effects only in first few weeks. ( IBS symptoms on and off in first year or so. | Back in 1969 I was given LSD and had panicked on the drug. It left shocked up and had depersonalization / derealization for several months. I was subject to return bouts every so many years and felt like I could not be free of the fear of the panic and depersonalization. Then in 1986 science finally caught up with me. Started Impramine in fall of 1986 and within 3 months was a different person. I had to work up to high dose of 300 mg. Changed my life... fear of return of anxiety disappeared. On it now for 32 years and doing great.. Gave me my life back. | M | 67 | 32 years 300 | 7/3/2018 | 5 | Depression | Dry mouth. I have to take Biotene to stop it | Absolutely wonderful drug. I have been depressed all my life. Started on imipramine at 27. Always gave me big orgasms and all anxiety, social phobia went away. Weaned myself off and tried the new Ssri's. None of them worked. They stopped the depression but ALL caused insomnia and loss of libido, not to mention not being able to orgasm. SSRI's will kill you sleep and your sex life. I hate them. Doctors push for you to go on them but that's only because of the kickbacks they get. I will never take them again you may be less depressed but your relationship and sleep will suffer. Not worth it in my book. I went back onI imprimine at 55 and there was no weight gain, depression, and anxiety. I slept as soon as I hit the pillow. My sex life is wonderful and orgasms have returned normally with the added bonus of them being big. Lucky me😀 Take what works for you. | F | 58 | 30 years 150 1X day | 2/20/2018 | 5 | Major Depression/Anxiety | dry mouth, low-to-no libido, insane sweet tooth, excessive sweating in summer, | Had terrible anxiety/panic attacks and depression for 8 months after my daughter was born. A GP had prescribed Elavil and Xanax, but that put me into a drug induced fog. I stopped the Elavil but continued the Xanax. Another GP told me to stop the Xanax, so I tried to do so but was unable to. I then got brave enough to see a psychiatrist who put me on Imipramine (25mg/day) and weened me off the Xanax. He gradually increased the dosage. It took about 10 weeks, but all of a sudden the black cloud lifted. Since then, i've been at a 250mg maintenance dose. About 13 years ago, my doctor tried switching me to Prozac. I gradually stopped he Imipramine while taking 20mg/day of Prozac. Once the Imipramine was stopped altogether, I felt like I couldn't sleep and had awful dreams that I would think about all day until I had new ones the following night. I spiraled back down very quickly. My doctor stopped the Prozac and put me back on Imipramine and ramped me up to 300mg/day. it took me about 10 months to get back to "normal". Imipramine is a miracle for me and well worth the side effects. | M | 54 | 27 years 250mg 1X day | 1/20/2011 | 5 | Panic Disorder | Dry mouth | I was having severe panic attacks and this medication saved my life. It worked very well for me. I took it for about 3 years after my divorce. Since then I only need it when in a very stressful situation. | F | 61 | 25 years | 12/9/2008 | 5 | Migraines | None | Helps control vascular headaches. Reduced occurrences of headaches from one per week to less than three per year. I periodically try to reduce dosage to 50 mg per day, but eventually the headaches begin to return. 75 mg per day dosage controls the headaches without additional medication. | M | 66 | 24 years 25 mg 3X day | 4/13/2010 | 5 | PTSD, Panic & Anxiety, Depression | Dry mouth, irregular heart beat, feel sedated but can easily wake up from it. I take dosage at night. | I've been on imipramine since 1985 (nearly 22 years). A few times I have tried to wean myself (self-imposed) off this medication only for it to back fire in severe anxiety attacks with physical pain. While taking imipramine, I feel like myself and normal. I would much rather take imipramine than an of the newer, less studied drugs. I've been able to function normally. I held a day job for over 20 years with no attendance problems and performing that job in terms "greatly exceeding standards". I'm also on 15 mg of clorazepate (anti-axiety). I've been on 75 mg of imipramine for many years but now feel that the tearfulness, chemical taste, and pin and needles feel on my arms indicate that the depression is still present or may have increased. I'm looking at increasing the dosage to about 125mg (under doctors care). I have never abused this drug. I have no suicidal thoughts and have been treated by my primary care physician. I also see a psychologist on a regular basis | F | 47 | 22 years | 1/1/2007 | 5 | Major Depression/Anxiety | Dry Mouth, Weight gain, Head rush when standing up quickly, Constipation. | This drug has helped me to have quality of life. I first took it when I was 23 for Major depression and Anxiety. The weight gain and Dry mouth are the worst side effects, however I tried taking Zoloft and Prozac. Zoloft helped but not like this drug, and while taking Zoloft I experienced sexual dysfunction. Prozac gave me the worst headaches. I was able to be drug free for about six years and then had a relapse, so I started taking it again. Hope this helps someone who's looking for some direction. God Bless | M | 49 | 22 years | 12/26/2009 | 5 | Depression and anxiety | Bit of constipation, postural hypotention, dry nose. Don't bother me | By far the best AD I have been on. I went on everything in the late 80's through to the 90's. All the SSRIs, MAOIs and some anti psychotics. SSRIs take away anxiety but did nothing for mood and depression. Made me feel hostile sometimes and numb most of the time. I had far more side effects on the SSRIs The literature says that it is as effective for panic disorder as the SSRIs and slightly better for depression. New DRs tend to use newer drugs which is a mistake and maybe because of the marketing of the newer drugs. If you are getting a partial response, you might need to increase but persevere because I find that it is a subtle drug and might take a bit longer. Only one problem, I live in South Africa and in the last few years they only make the 10mg tablet. It is a hassle taking 15 pills at night :( | M | 48 | 20 years 150mg 1X day | 5/23/2016 | 5 | Insomnia, anxiety attacks | I tried weaning myself off 8 weeks ago since I felt it had run its course. Within 3 days I developed tinnitus (ringing in ears) and IBS (irritable bowel syndrome). Two weeks later I was lethargic, emotional, irritable and mildly depressed. | By week 5 I had actually resolved the insomnia on my own but my stomach started getting worse and worse each day. I thought I had a urinary tract infection. I was bloated, constipated, emotional, lethargic, and mildly depressed. I continued to cut the dosage. Even consulted an herbalist and became a vegetarian. I finally got an emergency appointment with my doctor today, begging for a colonoscopy. Unfortunately, as I suspected, she told me to go back on the imipramine and that once I was back to 100 mg all of these physical symptoms would be reversed. Bottom line: as much as I hate being on something like this and I feel it may be toxic in the long term, I can't live with these side effects, or apparenly, without the imipramine. My doctor explained that I will probaby be on it for the rest of my life. I am ambivalent about this diagnosis, since I feel my anxiety and insomnia issues have been resolved, however, my quality of life over the past 8 weeks of going from 100 mg to 25 mg has been horrendous. Just my two cents... | F | 52 | 20 years 100 mg 1X day | 6/27/2013 | 5 | Depression | Taken for 20 years | F | 70 | 20 years 25mg 1X day | 11/28/2010 | 4 | Major depression | Dry mouth, urinary retention, blurred vision, "foggy" mental state, reduced libido, hunger at the end of the day that requires lots of exercise to counter. | I've tried about 15 other antidepressants to avoid the side effects, but (a) they're all less effective, and (b) their side effects are generally worse. Every doctor should be required to take a drug for 6 months before being licensed to prescribe it. | M | 51 | 20 years | 1/21/2006 | 5 | Migraines | dry mouth, funny taste in my mouth | I have been taking this medication every day for 18 years. I was experiencing extreme visual problems such as temporary blindness, double vision, etc... and had been through tons of doctors, procedures, tests... Tofranil was prescribed to me for what they suspected was migraines in the occipital lobe of my brain, although I never experienced headaches. I got better immediately and have been maintained on 75mg a day since. I was young, in graduate school and thought I was loosing my mind. This medicine saved my life. One strange thing I noticed right away. I get a very funny taste in my mouth if I am late taking a dose or miss a dose. Now I take the PM brand so it does not happen near as much. | F | 43 | 18 years | 3/19/2008 | 5 | insomnia | A Dry mouth makes me thirsty often, but that also helps me remember to drink more water. | If take none, I sleep from 11pm until 3-4am. I can take 50mg and wake up about 5am or take 75mg to wake up 6:30am or take 100 MG and sleep in until 7 or 8am. | M | 57 | 17 years | 5/16/2007 | 4 | clinical depression | Dry mouth, weight gain of 50 pounds, STRONG cravings for sweets. | I have been taking imipramine for 16 years as it seemed to be the only antidepressant that worked for me. I have tried going off it many times (because of the weight gain) and have found the symptoms of depression returned within a week (or are they withdrawal symptoms?). I would appreciate any info or tips others may have in how to successfully get off of the medication. I do not want to keep gaining weight.(I was thin all of my life until I started taking it). Thanks. | F | 49 | 16 years | 6/9/2004 | 4 | anxiety+depression | weight gain, cravings for sweets, irratibilty. | Good drug for me. I have tried the whole array od SSRI's and nothing compares to tofranil. | M | 40 | 15 years | 11/25/2004 | 5 | Panic Disorder | drowsiness, dry mouth and fast heart rate | This drug restored the quality of my life. I take 50mg at night. I was always a confident independent high achiever-I developed panic disorder literally over night. I was completely disabled by it. Forget the mind over matter stuff, i tried all the therapy going -this disease is a biological imbalance hence the instant "cure" thanks to imipramine. Within days of starting it, I was back to normal.The side effects sre nothing compared to constant debilitating panic attacks. I tried Prozac for 2 days and it made my panic disorder 100 times worse-nightmare. Imipramine saved me from a living hell. | F | 41 | 10 years | 3/14/2007 | 5 | SEVERE LEG PAIN FROM NERVE IN BACK | THIS MEDICINE STOPS THE PAIN CYCLE OF LEG NERVE PAIN & EVENTUALLY EASES SHARP PAIN DURING THE DAY. IT ACTUALLY SAVED MY LIFE BECAUSE THE PAIN WAS SO SEVERE. A DOCTOR IN LAS VEGAS PUT ME ON IMPARMINE I HAVE A LITTLE PAIN BUT NOT SERIOUS LIKE BEFORE I CAN FUNCTION ALL DAY WITH OUT MUCH TROUBLE THE MEDICINE LELAXES THE LEGS & STOPS THE PAIN NIGHTLY | I WOULD RECOMEND ANYONE SUFFERING FROM SEVERE NERVE PAIN IN THE LEGS DUE TO A BACK INJURY BE PUT ON THIS MEDICINE IT IS VERY VAULABLE TO STOP THE PAIN CYCLE & FUNCTION THE NEXT DAY | F | 69 | 10 years 50 1X day | 6/4/2011 | 5 | major depression, agoraphobia | Dry mouth and eyes, constipation,weight gain. I have taken it for 29 years, but site was not allowing me to indicate that from "smartphone". I was housebound before I started it. I had drowsiness at first, (at a higher dose, 125 mg), but that went away. Craving for carbs also eventually went away. Since I went on imipramine, I have held down jobs, gone to school. I would never want to go back to the life I had before taking it. | F | 56 | 10 years 50 mg | 9/15/2014 | 4 | for depression | F | 76 | 10 years 10 1X day | 6/6/2015 |
IMIPRAMINE HCL (IMIPRAMINE HYDROCHLORIDE): This medication is used to treat depression. It is also used with other therapies for the treatment of nighttime bed-wetting (enuresis) in children. Using this medication to treat depression may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. Imipramine can help your child control nighttime bed-wetting. Imipramine belongs to a class of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (neurotransmitters such as norepinephrine) in the brain. For bed-wetting, this medication may work by blocking the effect of a certain natural substance (acetylcholine) on the bladder. FDA Approval Date: 1990-06-05 (Sources: U.S. Centers for Medicare Services, FDA)