Drug Ratings for METHOTREXATE SODIUMAverage Rating: 3.4 (359 Ratings)
Compare METHOTREXATE SODIUM with similar: |
Results are sorted by Gender with females listed first (no age reported listed before females) Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
| RATING | REASON | SIDE EFFECTS FOR METHOTREXATE SO | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
  | F M | | | | |||
| 4 | RA | Nausea and vomiting, headache, itching, mild hair loss, sadness and weight loss. | My pain has decreased since starting to take Methotrexate. I also take Plaquenil. I feel I am trading one problem for another because the side effects are hard to handle at times. | F | 51 | 4 months 10 mg 2X W | 11/2/2010 | 4 | Autoimmune Optic Neuritis | When taking a higher dosage (25 mg) injected, some hair loss. Since switching to oral methotrexate, hair loss has stopped. General feeling of fatigue the day of taking it. I've never had an upset stomach from this medication. Some mild depression, however it could be associated with the prednisone I am also taking. Hot flashes occur, but may be due to hormonal changes as well. | In general, this is a well tolerated drug for me which has helped to maintain the sight I still have left. You need to have your blood checked to make sure it is not affecting your liver (about every 2-3 months). | F | 50 | 2.5 years 15mg 1X W | 11/6/2010 | 4 | colitis arthritis/ra | TIREDNESS!!! Im in a fog most of the time. Extreme blues two days after taking. Recently hot flushes...could be early menopause. Some nausea | I call these pills the beastie pills. But my life has certainly changed dramatically since taking, couldn't walk more than ten metres, couldn't stand for more than 1 minute. Now no swelling, pain minimal and am able to work again and go up stairs! For me the benefits outweigh the side effects. Recently I have been having more pain so will have to see rheumatologist again in two weeks and perhaps upping dosage. But compared to how I was 6 months ago, I am a different person. I was in a wheelchair when I had to go out! | F | 45 | 4 months 10 1X W | 11/20/2010 | 4 | Skin and joints | Initially on the tablets, last 6 months via injection. I found taking the dose right before bedtime helps tremendously with side effects. Have recently got the dry mouth (always in the night) and find the folic acid helps with the tiredness. | Having dealt with this condition for 26 years its the best thing I have ever tried that works. | F | 37 | 3 years 20mg 1X D | 1/20/2011 | 4 | Psoriatic Arthritis | I have not experienced any noticable side effects as of yet | I have noticed that after the 4th dose, my symptoms of the disease began to subside slowly. | F | 49 | 7 weeks 12.5 1X W | 1/21/2011 | 4 | RA | Mild nausea, which goes away after sipping ice cold aloe juice. Nausea seems less of a problem each week. | Have had RA joint pain in fairly frequent flares since May 2009, and was diagnosed with RA in Feb. 2010; RF, ANA, and CPP all positive. Pain was severe (7-10 on 1-10 scale) in shoulders, wrists, and hands, especially. After 3wks on MTX, flares can't seem to get much thunder - frequency, duration, swelling, and redness of flares are down 50%+, pain 3-4 at worst. I take Indomethacin 50mg if there is any inflammation to minimize erosion, but don't need it for pain anymore. Vicodin was required for relief from shoulder flares before, now untouched for several weeks. I have more energy than before. I think the pain and disease process were the cause of my extreme fatigue the past year. I'm hoping for remission. Everyone reading with AI diseases: have your Vitamin D level checked. A lot of us are deficient and don't know it. I was. | F | 50 | 2 months 7.5mg 1X W | 8/21/2010 | 4 | SARCOIDOSIS | severe hot flashes, depression is worse, severe sweating severe migraines | I have had Sarcoidosis for 9 years. Was put on the MTX a year ago for severe joint and bone and muscle pain associated with Sarcoid. I have been on pain killers for almost 20 years now. I was told the MTX would cause severe nausea when first starting it but I had bad migraines instead. It has really helped with my joint and bone muscle pain but the severe hot flashes are really really bad. I have to have a fan blowing on me 24/7. Have another Doctor appoint next month . Need to tell them to get me off the MTX. Having a really hard time handling it any more. | F | 54 | 1 years 15mg 1X W | 6/22/2010 | 4 | palmo-plantar-pustulosis and PA | At higher dosage, I had dry mouth, queasiness, tiredness | Dosage is actually in two units per week: 3 tablets (2.5 mg each) on Tuesday, and 2 tablets on Saturday. Folic acid (1 mg) every day. I also gave up most gluten food, follow the no-alcohol requirement, and minimal sun-exposure. I have low vitamin D levels and am supplementing to build that up. The MTX was a big help with the palmo-plantar-pustulosis form of psoriasis and PA, but I got several flu-like diseases in winter, despite inoculations. | F | 59 | 16 months 6.125 2X W | 6/25/2010 | 4 | mixed connective tissue disorder | Take on a Saturday afternoon. Wake up middle of the night with a bad headache. Sleep most of Sunday, feel "spacey" all day and feel like I'm coming out of the fog by Sunday night. Am going to begin to take it Saturday AM and see if I get more of my Sunday back. Hate missing a day out of a weekend. | Has helped greatly with foot joint pain. Took 4 weeks to notice the change. | F | 55 | 20 1X W | 7/4/2010 | 4 | palindromic arthritis | nausea and dizziness the first few weeks, but it went away. I take 15mg a week and when they tried to increase it the nausea and dizziness came back and didn't go away so I went back to 15. Helped with severity and length of flares. | F | 67 | 2 days | 8/14/2005 | 4 | RA | It took me a few months to build up to my 15mg dose as I suffered from nausea, tiredness, dizzyness and generally feeling unwell, but now that I am there I get very few symptoms, I also take 10mg of folic acid 3 days later, if I forget to take this a headache usually reminds me! | Although I am constantly tired, I lead a relatively normal life, which compared to my RA is brilliant. From November until the end of January I usually feel pretty crap, but as soon as spring arrives, I feel a lot better. Roll on Summer! | F | 36 | 18 months | 1/21/2007 | 4 | Lupus and RA | Nausea, vomiting, hair loss, extreme fatigue, sun sensitivity | I have no pain for the first time in years. I wish the side effects were less. I can't decide if I want to deal with the pain and stop methotrexate or deal with the fatigue | F | 44 | 7 weeks | 8/23/2005 | 4 | RA | mild mouth sores, stomach bloating, tiredness, losing my hair | really helping the pain and stiffness, slowed the progress of the disease, but also taking prednisone, Daypro, folic acid. Have gained 20 pounds since starting all the drugs and eat less. | F | 46 | 8 months | 5/21/2006 | 4 | Lupus -SLE | Extreme tiredness, sickness, facial rash, mood swings | I take 20mg per week, 10mg on Tuesday and 10mg on Friday. Taking the full 20mg together resulted in me feeling very sick, loss of appetite - losing approx 10kg very quickly. Generally now I dont seem to suffer from side effects but do get tired very easily and am very, very weak on my upper body. But I am now off steroids after 8 years and feel much better | F | 31 | 9 days | 2/13/2006 | 4 | Sero-negative arthritis | Nausea on the day of taking it, and sometimes the day after. can be pretty bad but not unbearable. Extreme problems with concentration, lethargy and fatigue - could quite happily spend the whole day in bed! | I take 25mg per week and it definitely helps my arthritis. I tried coming off a couple of years ago and instantly had a bad flare up so for now I'm happy putting up with the side effects! I've noticed some people on this site are saying they've had no benefit but have only been on for a few weeks/months - it took 6 months to really kick in for me so give it time... plus the side effects get less as your body builds up tolerance | F | 27 | 4 years | 1/11/2006 | 4 | RA | Nausea is the main side effect I have had; over the past few weeks I also have had weight loss, and loss of appetite | The side effects are far less discouraging than the effects of RA. I have more mobility, and was able to stop prednisone, and enbrel injections. I take 20mg once a week | F | 34 | 8 weeks | 4/7/2006 | 3 | RA and/or PA | moderate to severe hair loss, slight dizziness, occasional headaches. I am also fatigued, but I think it is due to the disease as much as the drug. I am more worried about long term use. | 15mg of methotrexate was not giving me any releif so upped to 20mg and still no relief so added 5mg prednisone and what a difference! I was able to get out of bed and function as a mother to 4 young children. Doctor is talking about trying Enbrel, but I am nerveous due to the increased risk of Lymphoma. | F | 36 | 11 weeks | 4/10/2006 | 3 | Junvenille Idiopathic arthritis | sore stomach, raised liver function tests | F | 4 | 14 months | 3/15/2006 | 3 | RA | Nausea,sensitive eyes,itchy scalp,tireness | Even though I'm only in my 2nd week I'm surprised I already have such symtoms.I'm only on 5mg,this increases to 7.5mg next dose.I am not sure why I've been put on this as I have very little pain although I do have joint damage.Having read some of the comments here I'm not sure if it's worth the risk! | F | 39 | 2 weeks | 3/24/2006 | 3 | RA | I take my 4 pills (10 mg in total) on Monday. For the next 48 hours after, I feel exhausted, head feels heavy and I feel really bloated. I have been having trouble sleeping and been very moody also. The symptoms for my RA have drastically improved but I just feel crappy for 3 days out of 7. Now I have to increase to 15 mg. starting my next dose. I hope it doesn't worsen the side effects. | F | 40 | 30 days 10 1X M | 2/29/2012 | 3 | R A | SLIGHT DIZZINESS AT THE START O.K NOW. | Feel nervous taking methotrexate,a pharmacist told me to try and get my doctor to prescribe something a lot safer.I dont . honestly know if its working that well for me as noticed 3 weeks ago a deformity at the side of my right foot, it looks actually like another little toe what is for sure working is (arthotec 75) its for pain and inflamation its brilliant....... | F | 42 | 4 days | 12/6/2005 | 3 | Lupus | from the first dosage i got a headahe that has never went away, (its just a dull ach) and for the first month i couldnt sleep at all, from sleeping all the time to not sleeping at all, hair loss, and mood swings, and really hungry it feels like i took an incress of prednisone, but im still on the same doasage. | all and all thou its good the side effects are not so bad | F | 21 | 3 months | 9/28/2006 | 3 | RA | Few to start with but recently, after being on it 6 years, I have been getting pain in my lungs, similar to pleuricy, and slight giddiness from time to time. Weeng isn't quite so easy as it was (perhaps this is age) and slightly scented even though I drink lots. Otherwise my joint pain is much reduced, although it still deforms. | 20 mgs weekly, with one folic acid two days before. I have managed to almost cut out naproxin | F | 62 | 6 days | 3/25/2006 | 3 | F | 42 | 4 months | 12/6/2005 | 3 | rheumatoid arthritis | Mouth sores initially. After about 3-4 years memory loss and breathing problems started. Neurologist suspected Altzheimers?. Had to discontinue. | Could go long periods with no pain killers. Seemed to stop RA progression. For last two years received Remicade infusions every two months. | F | 79 | 4 years | 10/10/2005 | 3 | RA | The only thing I have noticed is that I have had trouble staying asleep, It feels that every time I start to go to a deep sleep I wake up.. I am quite tired and do have a busy life so I don't know how much of it is the drug. Thats about it though.. hopefully that will be all.=) | I am on 5mg every Friday evening and after 2 weeks will be switching to 7.5mg every Friday evening. | F | 25 | 1 weeks | 10/17/2005 | 3 | Crohns | Sickness | F | 23 | 40 days | 1/30/2007 | 3 | Rheumatoid Arthritis | extreme fatigue, nausea, mouth sores, and stomach problems. | It has helped tremendously with the progression of the disease. I still have inflammation and pain on both hands after 9 months on methotrexate. I take on occasion, Naprosyn. I am afraid to take other drugs like Remicade, Enbrel, Humira. | F | 44 | 9 months | 10/3/2007 | 3 | Rheumatoid arthritis | Loss of hair! | I took methotrexate for about a year, and it worked ok. It was certainly better than nothing! Then my hair started falling out by the handful! Taking Enbrel now. Much better for me. | F | 50 | 1 years | 8/24/2005 | 3 | SLE (Lupus) | Nausea, dizzy/light-headed, weak, tired | Only started my first dose Wed. night of 7.5mg but felt very strange ever since. I take folic acid everyday. I just hope these side effects are normal and the drug will help my lupus. Feel free to contact me with advice etc. | F | 49 | 4 days | 5/12/2007 | 3 | Psoriatic Arthritis | I have only noticed side effects in the higher doses (I'm at 20 mg now and noticed side effects at about 15). Now, I get some mild nausea the day after taking the pills which usualy goes away with some food like rice or cereal. Very recently I've been getting some pretty nasty diarhea about 2 days after taking it. I've only been taking MTX for 3 months, so I'm hoping these side effects will go away once my body gets used to it. | When I started taking MTX, many of my joints were affected, now only my ankles, a few fingers/toes, and my wrists are affected. So I'm not giving up hope that I will continue to find relief. | F | 32 | 3 months | 2/25/2006 | 3 | RA | extrme tiredness, nausea lasting 4-5 days. felt ok on 10mgs but no pain relief so increased to 15mg weekly & huge increase in side effects. Experiencing vaginal thrush ??related Anyone else with this problem | F | 31 | 11 days | 2/13/2007 | 3 | Psoriatic Arthritis | Loose bowels then constipation. Dizzyness, nausea, mouth ulcers. | I first started on Sulphasalazine and had to build up to a dose but my Rheumatologist just started me on 12.5g a week with this. My joints seem a lot better though if I miss my Diclofenac I can still notice the difference. | F | 20 | 6 weeks | 10/8/2007 | 3 | RA | Some hair lost but could be related to stress. Acne went away. Slight sore throat. | My RA has not displayed the tradition symptoms only 3 joints inflamed at a time in an asymmetrical pattern, right ankle, both or either knee(s) (right wrist sometimes and left middle finger). All blood levels become normal after taking the medication for 3 months(RA factor, ESR, (ANA has never been a problem)) . I still have pain, for the first 1/2 hour after waking and the occassional flare. With 600 mg of Advil daily, prescribed by my doctor, I can function walk, climb stairs, swim, dance. | F | 31 | 8 months | 12/20/2006 | 3 | Rheumatoid Arthritis | Hives on my scalp and in my ears. Initially, sores on my tongue and in my throat, but they went away. Swollen abdomen. Feelings of inability to cope and hot flashes, so it messes with my hormones and an otherwise good mood. Helps in a positive way with the stiffness so that I can move, totally does wonders for my blood pressure, and helps with some of the pain. Was on Plaquenil for 2 years until it messed with my color vision. For now, it is better than nothing (I think) and cortisone is not an option. I have to totally fail all of the cheapest and oldest drugs before I can try any of the newer ones and then I'm sure even with insurance, it will be cost prohibitive so I still won't get enough relief. I work and like my job, so I'm not ready to pack it in. | If you have a doctor that tells you that your side effects are not from methotrexate, find a new doctor who wants to be a doctor instead of someone just after your money. The side effects are nasty, but having a doctor blow you off is worse. | F | 58 | 7 months | 6/23/2005 | 3 | RA | Virtually no side effects - slight fatique on day of dose. | Started taking Methotrexate 4 weeks ago (20 mg wkly for 1st 2 wks now at 25 mg wkly + folic acid + 400 mg Celebrex + prednisone 10 mg). Not noticing a big change yet although my symptoms have stabilized instead of getting worse. | F | 41 | 4 weeks | 1/30/2007 | 3 | SLE/SOJRENS SYNDROME | I TAKE 20MG EVERY TUES BEFORE BED AND SOMTIMES IT DOES MAKE ME FEEL SICK BUT MOSTLY IF I WERE NOT ON THIS I WOULD NOW BE OUT OF WORK.SO I AM GLAD I HAVE THIS AT LEAST | IT HAS HELPED ME A LOT | F | 47 | 3 years | 3/21/2007 | 3 | SJOGREN'S SYNDROME | So far, just Fatigue. I started last Tuesday night with only a single 2.5 mg pill due to my not reading the directions on the bottle. But this tuesday I took the 4 pills, which is 10mg, and today is Thursday, and I'm still so tired I feel like my eyes are sunk to the back of my head. My throat feels a little sore. Otherwise, no problems. But, I have to say, I stuff myself with pasta or pizza right before taking the pills. That might make a difference. I think since I'm missing work this way, I'm going to wait till Friday night to take it, since I have weekends off. That way I won't miss so much work! It hasn't changed any symptoms of the Arthritis yet, but I'm just starting. | I'm assuming I won't lose my hair since I am only taking 10mg. I don't have bad, bad symptoms of sjogrens...so I shouldn't need large doses. Since taking MTX, I have noticed bruised feelings in the salivary glands. I don't know if that's from KILLING the disease or what? ????? | F | 46 | 2 days | 10/9/2008 | 3 | rheumatoid/ late stills disease | nausea lasting up to 3 days after taking methotrexate, vomiting same night as taking. fatigue and not feeling as if Im all there - difficult to explain, mouth ulcers, bleeding gums skin sensitivity to sun light, lack of concentration, thining of hair and headaches. | Methotrexate has been fantastic at controlling my flair ups as I never thought I would get to this stage! BUT after being on 22.5mgs for 5 years the possibility of being on methotrexate forever is daunting! I'm fed up of feeling tired, not being able to concentrate and not being all there in social situations. Starting to feel depressed by this and weighing up the pros and cons on finishing treatment. | F | 20 | 5 years | 11/15/2006 | 3 | RA | Stomach sick for 2 days after taking meds. Nausea and diaherra. Lethargic. | Was on this medicine 3 years ago with Enbrel, Remicade and Humira. Stayed on Humira, methotrexate was stopped as sed rate was between 30-40. Sed rate up to 76, back on methotrexate with Humira and Leucovorin for the stomach symptoms. Don't see much difference. Stiffness, achiness, limited use of hands. Not sure what next steps are, see doc in 2 weeks. | F | 54 | 60 days 12.5 mg 1X W | 4/10/2010 | 3 | SLE, APS, MCTD | Stomach pain & bloating, nausea, severe headaches, diarrhea, sever lethargy | I've only been on this a few weeks. I can't tell if my pain is less or that I've got so much else going on I don't pay attention to the pain I'm "used to" Feel like crap all week. Was hoping to feel bad & then have it taper to feeling better every day - not so for me. Also, medication sensitive... | F | 45 | 2 weeks 7.5 1X O | 10/2/2010 | 3 | RA | I just started on this and feel very fatigued...like my muscles are just exhausted. 30 minutes on the elliptical felt like an eternity. I also get hot flashes (more than usual), sweat more, and feel out of it--especially the day after I take it. And this is weird, I feel like I want to cry out of the blue. No RA flares though...so that's good. | F | 43 | 2 weeks 7.5mg 1X W | 9/24/2010 | 3 | psoriasis, psoriatic arthritis | dizzy, nauseaus, migraine | took methotrexate a few months ago for 5 weeks and eyes became dry and very inflamed. Got worse with each week and could not put in contact lenses. Doctors said it was not from drug but I stopped it and symtoms went away instantly. Now on it again for two week and withing hours of taking it last night I have a horrible headache and had a migraine aura last night. | F | 57 | 2 weeks 15mg 1X W | 4/21/2011 | 3 | RA | Took MTX for a couple of years for Rheumatoid Arthritis without any noticeable effects, then stopped for about six months after I was also diagnosed with Crohn's and had emergency surgery. Since resuming MTX, I feel very tired and "foggy" most of the time and have increasingly bad short-term memory loss (I also take Remicade, Prednisone (5 mg/day) and Plaquenil, so it could be due to a combo of these drugs). | This drug has helped a great deal with joint pain, especially in combination with Remicade, but the tiredness and fuzzy-brained feeling is bad enough that it would be impossible for me to have a full-time job. | F | 32 | 3 years 15 1X W | 4/26/2011 | 3 | Inflammatory plaque-type Morphea | Nothing yet so I hope it stays this way | My doctor said that it takes time before you can see any results BUT some of my morphea patches look a lot lighter! So I hope it will only get better from now on | F | 22 | 2 weeks 7,5 MG 1X W | 6/14/2011 | 3 | RA | Fatigue/lethargy, mouth ulcers, lack of concentration, loss of appetite, bloating, sweats, awake in the night every night. | take every saturday and folic acid 5mg on sunday. by sunday night the swollen mouth is there without fail - boy it hurts. didn't realise what i was suffering because of these meds. i just want to sit and cry some days for no reason, so agree with the PMT comments. on the plus side, i can walk again, i can sit here and type. on the downside, constant frown with weariness, lack of concentration now starting to badly effect work. | F | 45 | 5 months 20mg 1X W | 8/2/2011 | 3 | Rheumatoid Arthritis | Nausea off and on, hair loss but, that is better with the folic acid, dizziness. | I initially took injectable and that gave me more nausea and more hair loss and I didn't notice any decrease in symptoms. Now I take oral in combination with Remicade. Not sure if it really helps but, I am told it works in conjunction with the Remicade. | F | 38 | 2 years 12.5 mg 1X W | 3/2/2011 | 3 | sarcoidosis | Tired, gasy, bloated....only the day of & a couple days after | F | 38 | 1 days 2.5 4X D | 3/17/2011 | 3 | Ankylosing Spondylitis | Very tired, very weak, mental fog, loss of memory, night sweats. Hot flashes and acne. (went thru menopause 20 yrs.ago!) Panic attacks. Very irritable sometimes. | Seems too early to judge drug yet. Adjusting schedule to cope with tiredness; groceries, chores, friends, etc. Am taking less Vicodin,etc; however still lot's of pain in back, hips, knees, hands... | F | 60 | 5 weeks 25 MG 1X W | 8/17/2011 | 3 | Lupus | Headache and sore mouth | I haven't been on it long so I'm checking out this site to see if the side effects are normal and worth the benifit that the drug might bring to Lupus pain. | F | 31 | 2 months | 9/2/2005 | 3 | Psoriatic Arthritis | Severe fatigue (bedridden) the day after the dose (10-12 mg) and sometimes the day after. Mouth is sore but no visible/treatable sores, a head full of cotton, can't think straight | I have a few good days between weekly doses but if I happen to catch a virus I'm in bed with that. Doc said it takes time to adjust; after four months it's starting to get better | F | 48 | 4 months | 9/6/2005 | 3 | Rheumatoid Arthritis | Extreme fatigue, sleepiness, brain fog. Also slight dry mouth and lips. Oh, and dysphasia... hubby said I "sounded drunk" yesterday a few hours after dosing. but, I'm only 1-1/2 days status post 3rd dose, and dose was started low and increased to full 15 mg only this week, so I'm hoping fatigue will subside by tomorrow or so. | Morning stiffness and over-all stiffness and pain do seem better so far. Not crazy about the fatigue, but I think it's better than the pain and stiffness. | F | 46 | 22 days | 9/22/2006 | 3 | rheumatoid arthritis | neausea, extreme fatigue, headache | it helped a good deal for 9-12 months. Then it did not seem to be effective and the dr continually raised my dose until it got to the dosage that I could not handle. I went off it for several months when I started Remicade. Now I take 5 mg per week to work with the Remicade. The side effects are not as made at this dosage. | F | 34 | 19 months | 1/5/2006 | 3 | RU | head ache pukey feeling, loss of appetite,fever that comes and goes | F | 52 | 6 weeks | 11/12/2001 | 3 | R. A.(Adult Onset Still's Diasease) | i think this drug gives me nausea and is making me lose my hair and also decreasing my immune system. but i can be sure because i also have taken high doses of cortisone that may have the same efects. | i went on methoaxate to faclalitae getting off high doses of cortisone(80mg) it seemed to have helped at some point but now i think the side effect are worse. but i can be sure my side efects can not be attributed to my daily cortisone because i alredy have those (cushing? syndrome> round face, hump, incresed body hair and loss of hair. i take 22.5 mg of methotrexate and 5mg of cortisone now and want to get off both but i am still in pain and afraid of getting a flare up of my disease wich is rae and very severe. | F | 20 | 6 months | 7/24/2003 | 3 | Psoriatic Arthritus | Headaches, Chills, Nausea, Vomiting, sore throat, memory loss/short attention span, extreme phatique, weakened immune system (got sick constantly), 2 bladder infections (don't know if was related to methotrexate or not) | The side effects were always worse the day of the treatment and would get a little better w/ each day. It did not help the psoriasis at all. It helped with the arthritus but my hands and wrists are still very sore. I wear wrists splints to bed. | F | 28 | 12 weeks | 1/28/2003 | 3 | rheumatoid arthritis | nausea, severe weight loss, diarrhea | F | 39 | 1 years | 2/1/2003 | 3 | RA | some naseau and intestinal complaints for many years but increased infections including pnemonia. Had to stop taking for 2 months recently due to pnemonia. After restarting the side effects are far worse including naseau/vomitting (couldn't keep anything down for 3 days). Severe headache that kept me pretty much bedridden and also diarhea. | It is very effective. During the two months that I wasn't taking it, I became painfully aware of what it was doing for me and couldn't wait to begin taking it again. Not sure that was so smart at this time though due to the new side effects | F | 47 | 7 years | 12/7/2004 | 3 | sarcoidosis stage IV and asthma | stomach problems with the initial weekly dosage. Thursty, easily agitated and tired. | I have been on high doses of prednisolone 100mg daily for 5 years. My sarcoidosis is in the fibrosis stage and the methotrexate is helping me lower my dosage of prednisolone. With my white blood count high my doctors are trying to lower the prednisolone to 10 mg a week and switch to remicade with the methotrexate. I have been researching the side effects of methotrexate and remicade. I have monthy blood tests now and so far so good. If anyone else has sarcoidosis and is on methotrexate and remicade I would appreiate your comments. | F | 51 | 6 months | 9/20/2004 | 3 | psoriatic arthritis | For the first five months, actually, I didn't notice much of anything, but now that my rheumatologist increased my dosage, I'm starting to feel the shortness of breath and dizziness that every side-effect page has since warned me about. Since the dizziness came with a sore back, a sore throat, a fever, and a cough, I assumed it was the flu or something similar. | Methotrexate for me has worked really well for the first few weeks after I started it, and the first few weeks after my doctor increased the dose. But afterwards, I have had pain every morning and some days when it is almost unbearable, although for the most part after noon, the pain is controlled, while the swelling remains constant. | F | 17 | 7 months | 1/10/2005 |