Drug Ratings for METHOTREXATE SODIUMAverage Rating: 3.4 (359 Ratings)
Compare METHOTREXATE SODIUM with similar: |
Results are sorted by Satisfaction from highest to lowest Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
| RATING | REASON | SIDE EFFECTS FOR METHOTREXATE SO | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
  | F M | | | | |||
| 5 | Crohn's Disease | No side effects besides some upper back pain. I felt a huge improvement in my health after just 2 weeks and all of my symptoms have disappeared. I was very anemic and couldn't put on any weight, had bloody diarrhea and rectal pain, night sweats, skin problems, arthritis, eye inflammation, and absolutely no energy. The folic acid that I take keeps away the mouths sores. | F | 25 | 3 months 25 mg | 6/10/2012 | 5 | Rheumatoid Arthritis | Terrible, terrible nausea for 2 days after dose, diarrhoea, tiredness BUT cures my arthritis and allows me to live an active life free from pain. Side effects mean I struggle to keep taking MTX consistently, when I do my arthritis is cured. | F | 23 | 11 years 20mg 1X W | 6/8/2012 | 5 | RA | very slight nausea the first few doses, but none after that. | I think MTX gets a bad rap. Never had a problem with this drug; been taking it since 2007. Along with Enbrel injections and folic acid to reduce (in my case, eliminate) any side effects, my RA is effectively controlled. | F | 49 | 1X W | 3/18/2012 | 5 | Seronegetive RA | loose stools at times | For about 1 month my ankles and joints hurt so bad I couldn't wear heels and it hurt to walk. I went to the rheumatologist and he started me on methotrexate 10mg/week and prednisone 10mg/day. I ended up getting off the prednisone after a year and instantly after I started the meds my joints felt great and I was able to be active again. Last year I was in numerous races, bike rides & ski events all because of the methotrexate. I'm very thankful for the increased knowledge the medical world has about RA. Hope someday they will find the true reason behind this disease. | F | 23 | 1.5 years 10mg 1X W | 1/18/2012 | 5 | Rheumatoid | within 24 hours horrible migraine, tired, can't remember things, can't form the words I need to say, hot flashes, weight loss (good thing for me) | the benefits far outweigh the side effects I experience. the folic acid appears to be helping with the side effects but still have to take pain pills for the migraine for about 2 days. | F | 46 | 60 days 15 mg 1X W | 12/27/2011 | 5 | RA | I DO HAVE A BIT OF MEMORY LOSS AT TIMES AND HOT FLASHES MORE THAN BEFORE. | I TAKE METHOTREXATE ONE TIME PER WEEK AND PREDNAZONE DAILY, THIS HAS CHANGED MY LIFE SO MUCH,I AM NOW DOING THE THINGS I LOVE TO DO SUCH AS GARDENING AND I CAN DO MOST ANYTHING I HAD DONE BEFORE, I AM HAPPY. | F | 56 | 16 weeks 4 PILLS 1X W | 9/28/2010 | 5 | rheumatoid arthritis | still tired-often stay in bed on Saturdays after taking meds:5 pills Fri. night and 5 on Sat. am,some nausea, weakness. Just increased to this dosage in July. | In May was completely off of predisone taking only Methotrexate, but in June started having some recurrent pain, hips, hands, shoulders, feet. Methotrexate dosage to 25 mg in July. Pain still present, but not unbearable...still a miracle drug for me, compared to before methotrexate. | F | 48 | 7 months 25mg 1X W | 7/28/2010 History | 5 | sero-negative R/A | no side effects | Did not work as well for me w/o Arava 20 mg daily. Blood labs have always been fine. Some gastro problems from time to time. Tried once to get off both drugs and flared terribly. The two must work together for me. | F | 65 | 15 years 15 mg 1X W | 7/23/2010 | 5 | RA | Fatigue, upset stomach, mouth sores, elevated liver enzymes | F | 40 | 1 years 10 MG 1X W | 7/8/2010 | 5 | RA | I am writing this for my husband. He has had mouth sores from the start. | The methotrexate was working wonder for the first month. Now though since he has started taking the Remicade with it he has been exhausted to the point of being able to sleep all day or just falling asleep unexpectedly through out the day,headaches but the biggest thing is leg fatigue and weakness with muscle pain. | M | 33 | 2 months 2.5mg 1X W | 3/17/2010 | 5 | Polymyalgia rhematica | tiredness, but really nothing else. | To stop stomach problems, I wrapped each tablet in a ball of cheese and took about 2 hours before bedtime. Did not expereince any sickness or stomach problems this way. | F | 48 | 6 months 25mg 1X D | 2/7/2010 | 5 | SLE & SOGREN'S | I have battled for years with connective tissue disorder. Now named Lupus and Sjogren's. The pain was debilatating. I tried plaquenil and could not tolerate the emotional changes I lost my joie de vive. Started MTX 3 months ago, just 7.5 mg. Get tired and nauseated about 36 hours later for about a day. My biggest concern is the link to lymphoma. I have caught a virus rather quickly (within 2 days of contact) and wonder about how to deal with that problem as well. | This drug has given me my life back. I have not been so pain-free and almost normal for many, many years. With all of the valid concerns with this drug I do wonder however if I am trading my tomorrows for wonderful todays. But isn't that what autoimmune illness is all about anyway? My constant high (100) ESR counts and inflammation take my todays and threaten to distroy chances for good tomorrows also. | F | 47 | 12 weeks | 12/30/2009 | 5 | RA | first off this sucks!! before i started taking methotrexate i could not button my blouse,tie my shoes,open jars,pick up the milk jug,or open a bag of cookies..i couldnt even get down into a bathtub..now i can do all of this.. | i take 6 methotrexate 2.5mg once a week i also take prednisone 5mg every day and 2mg of folic acid everyday except on methotrexate day.. i have no hair loss i do get sick on methotrexate day and the day after i do dread those days but i will continue to take it.. it does do the job! I RECOMMEND LOTS OF WATER ON METHOTREXATE DAY TO GET IT FLUSHED OUT OF THE SYSTEM DONT LEAVE IT THERE TO AFFECT THE LIVER! | F | 53 | 5 months | 10/15/2009 | 5 | Psoriatic Arthritis | occasional lethargy, poor concentration, loss of appetite, some depression. | I have been on methotrexate for 4 years now, I started on 40mg a week orally and now I take 10 mg per week. This drug has literally saved my life, before taking it my skin was like sandpaper and my joints were so swollen I could barely walk and was in constant pain physically and emotionally. Within three months my skin was clear and I was back exercising. I now play sport three times per week, run and lift weights........the side effects for me are bearable and are worth it. | M | 30 | 4 years | 10/11/2009 | 5 | Ankylosing Spondylitis | No side effects experienced. Tolerated the drug very well. | Worked perfectly. Didn't experience any side effects (except the occasional mouth ulcer). But, I've always been pretty good at tolerating drugs. | M | 21 | 2 years | 9/23/2009 | 5 | PsA, Psoriasis & Anterior Scleritis | Fatigue, but generally MTX has changed my life. Though I still have some areas of psoriasis, without MTX I have watery blisters & psoriasis covering the soles of my feet as well as my hands. MTX helps my arthritis tremendously and my eyes are much better. Even when I experience side effects I'm afraid to quit taking MTX for fear the problems will return and I'll be handicapped. | I take 6 pills (5mg (2 pills at a time) spread over 36 hrs every Sun/Mon and prescription folate everyday. I've started having B-12 shots every two weeks. This seems to help my energy levels. Since starting MTX my dose has had to be increased twice. Starting out on a lower dose (even though my doctor recomended against it) helped me adjust to the medication - this is my opinion, not the doctors. | F | 53 | 2 years | 9/9/2009 | 5 | rheumatoid arthritis | fatigue and bit of mental fog. One knee hurts if I 'overdo it', shedding hair worse than the cat!! Grows back though. | Got RA and went from hero to zero in 3 weeks. Landed in hospital and got 2.5 grams of prednisone intravenously and more directly into my knees. Got it under control, home in 5 days, off crutches in 3 weeks. Take 20mg of MTX per week since March 09, plus folic acid and colcalciferol. Starting to wean off 20mg of steroids. Blood work is coming back fine. RA symptoms largely gone. Will be interesting to see if the MTX can hold the fort once the steroids are off the menu. Take fish oil too. | F | 52 | 5 months | 7/12/2009 | 5 | Psotiatic Arthritis | When I was taking the pills, like one user, I became so sick, vivid dreams (at about 25 mg). My doctor switched me to subcutaneous shot injections that I give myself once a week and I am fine now. Methotrexate has given me my life back. I sometimes wake up with a headache but everything is minimal now | F | 12 years | 5/23/2009 | 5 | RA | The drug was amazing when I first started taking it and increased up to 20mg (x10 tablets), however after 3 years of taking I started to feel sick they day I took the drug and the day after. My dose has gradually decreased and I am now on 5mg, I still get the sickness and hate taking the drug and dread the day I have to take it. Although I cant complain I suppose as I have responded much better than some people might have. | Taking folic acid everyday except the day you take the methotrexate and also anti-sickness tablets may help | F | 26 | 3 years | 5/14/2009 | 5 | Crohn's Disease | None, except worsened hangovers. | This drug is a wonder drug! Have tried many others including corticosteroids, mesalazine, mercaptopurine, allopurinol etc. This is the only drug which keeps my symptoms under control without the nasty side effects of corticosteroids. I take 20mg/week and find I have very little trouble. I would reccommend to anyone who has tried other drugs but suffers from flare-ups. The only downside is having to limit your alcohol intake, but I still go for nights out - I just suffer from extreme hangovers if I over-do it | F | 20 | 6 months | 3/9/2009 | 5 | RA | loss appetite,stomach problems.there both just happend when I take the medicine day. | I have had RA for 20 years and have taken methotrexate for 14 years.I take 7.5mg METHOTREXATE once a day.I also take Folic Acid everyday.and LEFLUNOMIDE once a other day.I feel all medicine didnt help 100% for my RA. But I have my life back.I do worry pulmonary fibrosis and andhepatocirrhosis happend someday.I had knees replacement two years ago. | F | 44 | 14 years | 11/18/2008 | 5 | Ulcerative Colitis | Been taking METHOTREXATE for 6 years - had bad nausea for the first couple of years, now only occasionally. A bit of hair loss at first, now OK. Worth persevering. | Before taking METHOTREXATE I was in hospital for a week or two every couple of years. It has been a 'wonder drug' for me. The additional benefit is I no longer have problems with asthma, used to have to use oxygen during the Winter now no symptoms at all. I take 15mg once a week. | M | 61 | 6 years | 9/16/2008 | 5 | RA | minor hair loss when doc increases the dosage. | I have had RA for 25 years and have taken methotrexate for 15 years. I have taken it orally and by injection. I am currently taking 8 tablets (2.5 each) once a week. My insurance doesn't cover the injections anymore, so have to take the tablets. I am getting over a major flare because I quit Humira, so doc had upped my dosage. I am back on Humira and expect to be able to back off some on the methotrexate. These two work well together and I feel like I have my life back! It takes awhile, about 6 weeks, for it to kick in whereas Humira did after the first injection. By the way, the minor hair loss goes away on the lower dosages and does grow back. | F | 55 | 15 years | 9/16/2008 | 5 | RA | MTX took over 6 months to take effect. Some minor problems the day I took the shot for several weeks. Raised blood pressure for several months. Now after 18 months I feel good and exercise a lot but still have joint inflamation. Could not go over 12.5 without raized liver enzimes. Take 2 folic acid daily. | Not sure if I want to stay on MTX long term. I am stablized but not "cured". The biologics are the only alternative and I can't afford the copay. | F | 65 | 18 months | 7/26/2008 | 5 | For RA | None | I took 6 pills per week for about 6 mos.(beginning in April of 2007). I also took prednisone (5mg daily) for about a month. In October I started to ween off methotrexate, each 6 weeks I take one less pill. Now I'm taking 1 pill and in July 0 pills. Doing great with very little or no pain. | M | 65 | 13 months | 5/5/2008 | 5 | RA | Very tired, weight gain, fluid retention. | Methotrexate has really helped my RA and life is enjoyable now except for the side effects. | F | 46 | 6 days | 2/27/2008 | 5 | pharisis, fibromyolgy | nausa,diarrea | F | 61 | 30 days | 2/11/2008 | 5 | RA | Worked down from 20mg to 10mg weekly Methxate have been at this for 7 months plus daily 200mg Hydroxychloroquine. Feel absolutely great no side affects and no RA symptoms. It was the Prednisolone in the beginning which upset my intestines. Off that now. Almost tea-total, eat carefully and exercise plenty. | Do I come off or stay on the Methxate, seems its a lottery. If it comes back it could come back worse than before and I believe treatment may be more difficult. If staying on, what silent damage is being done by the Methxate. Consultant is happy to go with whatever patient feels comfortable with. Seems there's not a clear choice to make. (I'm trying to make that choice but need more info). | F | 41 | 19 months | 12/27/2007 | 5 | RA | Slight nausea - often the day after taking the weekly dose. Fungal infections of the skin (ankles, legs, fingers) at least once a year, generally during the summer months. Developed a staph infection at the site of a metal plate in my great toe. Had to be hospitalized for surgery to remove the plate and treat the infection. Persistant diarrhea and abdominal cramps - don't know if this is from the metho or unrelated. | This drug has really helped me live as normal a life as possible since I started taking it in 1984. The few times that I've had to stop taking it - usually when I'm having some kind of surgery - my disabling arthritis symptoms return fairly quickly. I know this drug can have dangerous side effects, but on balance taking it has been worth the risks. My doc's have wanted to increase my weekly dosage from 12.5 mg to 17.5, but I haven't done this because I'm worried about more frequent and serious skin infections. | F | 62 | 23 years | 11/25/2007 | 5 | RA | Loss of sex drive, tiredness - think I can link these two to the drug | Having been on 15mg for past 4 years and having almost full mobility (pain in wrists and knees from time to time) I think this drug is fantastic. I'm now into my 2nd week without it and am terrified the pain and immobility will come back. my reason for stopping the drug is that I hope to conceive next year. | 31 | 4 years | 10/29/2007 | 5 | RA | I have had no noticeable side effects from my dosage of 15 mg once weekly. | It has made a significant improvement in my RA. I have not had any serious disease progression since I started taking it. I supplement the methotrexate with an anti-inflammatory as needed - usually a couple of times a week - depending on my physical activity level. | M | 61 | 3 years | 10/13/2007 | 5 | Psoriatic arthritis | For the past 2 years limited to catching anything that goes around when i have pushed myself too hard, but in the last month I have had 2 outbreaks of unexplained rashes, and have now caught Bell's palsy virus - I am wondering if this is related to the methotrexate??? | F | 46 | 2 years | 7/9/2007 | 5 | Lupus | Some lower gi upset after taking it the first 2 weeks but that has subsided-thankfully! I am now up to 20 mg once a week - I have been on it almost eight weeks now. I believe I am experiencing some hair thinning as well. | The last month has been so amazingly bearable. I am finally able to get up stairs w/out pulling myself up the railing and am able to walk w/out limping and w/ only an occ. twinge of pain. Joint pain has been substantially alleviated. I feel very hopeful at this point about having a life like I had before all this muck began... | F | 36 | 8 weeks | 6/13/2007 | 5 | Dermamyositis | memory loss, very tired for the first few days | This drug has been a miracle cure and a life saver. I went from not being able to walk, sit up, and barely comb my hair, in addition to my throat muscles barely working, to almost full recovery.I started with 20mg per week but had a great deal of hair loss. I cut down to 17.5 and hair grew back. Started at 60mg per week of prednisone but now am down to 5mg.I tried cutting out prednisone but symptoms reappeared. | F | 52 | 1 days | 6/11/2007 | 5 | RA | None that I can tell. | It's done wonders for me! I've been taking 12.5 mg weekly along with 1,000 mg of sulfazine daily. I also take fish oil & folic acid daily. When first diagnosed in May of '06 I was on prednisone along with the other drugs. I weaned myself off the prednisone this winter & feel fine, except for minimal stiffness in hands & sometimes achy hips. Get quarterly blood tests to check for kidney & liver damage. So far so good. | F | 47 | 12 months | 5/17/2007 | 5 | Psioritic Arthritis | To start with nausia and I still get fatigue and flu like symptoms 24 hours after dose. My hair thinned slightly but also went curly and blond (origionally poker straight and mousey) so not all side effects are bad. | F | 40 | 10 years | 4/6/2007 | 5 | Palmoplanter psoriasis | Fatigue for few days after each dose. Loss of sex drive. Some hair loss (patches) | This has been a wonder drug for me as every previous attempt to control the condition has failed. Almost complete remission of psoriasis and therefore the side effects are worthwhile. Had a recent bout of flu that lasted a month - was this extended period a side effect? My doctor thought it may be but can't be sure. | M | 48 | 1 years | 3/8/2007 | 5 | rheumatoid arthritis | tiredness,nausea and skin is itchy | i thought i would be in a wheel chair for life after wakenig up one morning and could not move or stand any one to touch or pull on me. it was a miracle drug for me. | F | 71 | 8 months | 2/15/2007 | 5 | Psoriasis and psoriatic arthritis. | Some nausea and strange relationship with food, which reminded me of pregnancy sickness (suddenly take revulsions to things like tea). Have quite flu like symptoms on the day after taking it. Usually go to bed on the Friday night, early - I take 15mg on Thursday night. Sickness starts Friday lunch time. Get odd bouts during the week but it's better than coping with my skin the way it was and the pain I was in. | My psoriasis disappeared like snow off a ditch at first. Was virtually clear in about six weeks. No improvement in my joints at first. Then my skin broke out again and the dose was put up. Skin improved but still have some patches but this time I had a few months of being almost totally pain free. Pains have returned a little, actually quite a lot at times but I'm not taking anywhere near the amount of pain killing medication I used to. There doesn't seem to be any rhyme nor reason to how it works. I read one patient say we are all hysterical as he/she has no side effects. Pure luck. I was also violently sick when I was pregnant - not all women are. Different people react in different ways. I have been having palpitations, which I have never had before. My Dermatologist says it's not a side effect he knows of. Anyone else experience this? Also I have very dry eyes - something else my Dermatologist has not heard of, though my optician has. These are all new things to cope | F | 50 | 1 years | 12/6/2006 | 5 | rhuematoid arthritis | F | 42 | 16 months | 11/30/2006 | 5 | psororiatic arthritus | none the arthritus started diminishing in the first week after 20 years of pain ,short term memory loss is there but as i am in my seventies this goes with the territory.after 20 years of severe pain i think M is great and i am only into my third week | it started working for me within three weeks, only time will tell what the long term situatin will be, the specialist reckons three months time i should be ok | M | 74 | 21 days | 10/9/2006 | 5 | Rheumatoid Arthritis | Mouth ulcers, bleeding gums for one or two days after taking dose, loss of concentration and memory,debilitating night sweats,bowel upsets, often severe depression. | I take 15mg once per week, together with ciclosporin 50mg caps x 2 per day, 5mg Folic acid x 2 per week. I was diagnosed in 2002 and tried other drugs which did not work.Methotrexate was initially prescribed at 10mg, and was later increased to 15mg with the addition of the ciclosporin. This worked very well and I had little pain and no inflammation. But I got scared and came off the methotrexate.Within weeks the symptoms of RA were so bad that I was in constant pain, my knees, wrists, elbows and even my jaw became inflamed.The day before my daughter's wedding I had to have steroid injections into my knee and hip to enable me to walk at her wedding.I went back onto the methotrexate asap and have had few problems since.Methotrexate is a frightening drug but RA is a devestating disease. Taking methotrexate means that in many ways I am not the person I was but I can function reasonably well.Without methotrexate the RA would mean that not only would my life be blighted, but the lives of al | F | 55 | 3 years | 10/2/2006 | 5 | Crohn's Disease | hair loss, extreme loss of energy, complete loss of appetite (no interest in food what-so-ever, even foods I normally find appealing), some nausea, general flu-type feeling | 10/mg injection taken weekly, usually given in stomach. In general, despite my loss of energy and complete loss of appetite, it has helped control my disease pretty well so far. | F | 21 | 2 months | 7/15/2006 | 5 | RA | I feel competely fatigue most of the time. This may be due to the RA. I usually feel worse day after taking it. I normally take 15mg a week. I also take 5mg of Predisone daily,200mg celebrex daily,Inbrel injection once a week, & folic acid. My mouth gets dry, may have a sore once in a while. I generally have not feeling well feeling, you know what I mean. I play golf at least 4 times a week. Without Methotrexate I couldn't do this. As I write this I have had to stop the drug, because of some lung problems. Pulmonary Fibrosis. I will be off methotrexate for 2 months & then repete test on my lungs. | Methrotrexate has done wonders for me. I was able to hold down my full time job. I still had RA flare ups, but they usually would just last a day. I did have to get off drug once because of liver test came back bad. That cleared up next test. | M | 66 | 13 years | 7/12/2006 | 5 | Rheumatoid arthritis | I guess you mean unwanted side effects: appetite loss, nausea. Among the unexpected pleasant side effects was relief of profound fatigue. | Just a general caution to double check what your physician prescribes and what your chemist dispenses. My own physician (very senior indeed in UK, should have engaged brain first) wrote the prescription as a daily dose on the monitoring sheet. Without being too alarmist about this drug that is excellent when correctly prescribed and dispensed, errors have caused fatalities here. | F | 58 | 4 months | 7/9/2006 | 5 | Rheumatoid Arthritis | Tiredness at times but not sure if that is just down to my condition or the medication. | This medication has made a massive difference and I have had little problems since taking it. I do not suffer with as much pain and stiffness as I did when I was younger and can therefore lead a better quality of life. | F | 29 | 7 years | 7/9/2006 | 5 | Rheumatoid arthritis | Minor - Tiredness and memory lapses day after taking BUT had this every single day with active RA! I time it so that sunday is my lazy day! | An excellent drug which has provided huge relief from active RA. Side effects might sound bad, but my experience is that they are insignificant compared to activive RA. Be patient when starting, it can take many months to acheive full benefit, plus the side effects of nausea normally lessen - also takes time to optimise your dose. | F | 34 | 11 years | 6/27/2006 | 5 | RHEUMATOID ATHRITIS | WHEN I FIRST STARTED TAKING IT 3 YEARS AGO I HAD SOME TINGLING IN MY MOUTH, BUT MY DOCTOR PRESCRIBED 5MG FOLIC ACID A DAY AND THAT TOOK CARE OF IT. I DO HAVE PRETTY BAD FATIGUE STILL, COULD BE THE METHOTREXATE, OTHER MEDS I'M ON OR JUST THE R.A. ITSELF. | I HATE THAT IT HAS POTENTIALLY LIFE THREATENING SIDE EFFECTS BUT WHEN YOU ARE IN DEBILITATING PAIN AND YOU CAN'T GET OUT OF BED WITH OUT HELP WHAT CHOICE DO YOU HAVE? SO I CHOOSE TO TAKE IT AND LIVE RELATIVELY PAIN FREE. | F | 40 | 3 years | 6/21/2006 | 5 | Rheumatoid Arthritis | I have taken multiple medications for my RA over the years. I currently take Methotrexate 17.5 mg weekly, Prednisone 5 mg daily along with IV Remicade every six weeks and I'm currently doing very well, no pain and no inflammation. I suspect that the Methotrexate is causing some hair loss but compared to how I use to feel--to me, it's worth taking. And with the Remicade it does increase my chances of lymphoma but, again, I'm able to function and live a "normal" life! I can't worry about what if...I need to live for today! | F | 44 | 3 years | 5/7/2006 | 5 | R A | none | best thing ever I feal great I have my life back | M | 18 months | 5/7/2006 | 5 | RA | Loss of sex drive nausea tiredness | Before i took this drug i could not walk for the pain it has helped me get my life back | M | 39 | 1 years | 4/20/2006 | 5 | RA | Loss of sex drive nausea tiredness | Before i took this drug i could not walk for the pain it has helped me get my life back | M | 39 | 1 years | 4/20/2006 | 5 | Linear morphea | None. | Has helped the morphea greatly. Patches are less thick and dark. | F | 28 | 3 months | 2/16/2006 | 5 | Psoriatic Arthritis & Psoriasis | 15mg Methotrexate (MTX) / week, tablet form. A few hours after taking MTX I get extremely drowsy, so now I time it just before bed with a cup of milky hot chocolate. Sometimes the following morning I wake up with a thumping head-ache, but by mid-day the head-ache is gone, I feel groggy though (bit like jet-lag). I'm used to it now, after being on it for six years. I still have to go for monthly blood tests so that my local Hospital can monitor my Liver function. My hair pre-maturely has gone grey :-( this is definitely due to MTX because my brother who is older than me still has pigment in his hair ! But I can dye it so no big deal. I feel as though I'm a little more emotional / less patient ? but that might just be old age creeping up on me. Sometimes it takes a long time for my blood to clot if I cut myself during shaving but I've got used to that now and I'm more careful. Sometimes I take the odd 5mg tablet of Folic acid but can't say that I really notice the difference. Since being | Its a horrible thing to have to take and its a life sentance but if you weigh up the pros & cons my experience is that its worth taking the risk. For me, its meant having an almost normal quality of life and has made the management of the two incurable diseases bearable. Ohh and by the way, it has NOT affected my fertility at all ! | M | 39 | 7 years | 2/7/2006 | 5 | Psoriatic Arthritis & Psoriasis | 15mg Methotrexate (MTX) / week, tablet form. A few hours after taking MTX I get extremely drowsy, so now I time it just before bed with a cup of milky hot chocolate. Sometimes the following morning I wake up with a thumping head-ache, but by mid-day the head-ache is gone, I feel groggy though (bit like jet-lag). I'm used to it now, after being on it for seven years. I still have to go for monthly blood tests so that my local Hospital can monitor my Liver function. My hair pre-maturely has gone grey :-( this is definitely due to MTX because my brother who is older than me still has pigment in his hair ! But I can dye it so no big deal. I feel as though I'm a little more emotional / less patient ? but that might just be old age creeping up on me. Sometimes it takes a long time for my blood to clot if I cut myself during shaving but I've got used to that now and I'm more careful. Sometimes I take the odd 5mg tablet of Folic acid but can't say that I really notice the difference. | Since being on MTX my un-stable skin psoriasis is now very well behaved and I only have a few small patches left which I treat topically with Exorex lotion (yellow, banana based coal tar). A Huge improvement and my quality of life is 10x better ! My Psoriatic Arthrtis (PA) only effects a few of my toes and I can't help feeling that going on MTX when I did stopped the PA dead in its tracks and no new joints (thank God) have been affected since I've been on MTX. So I guess you could say I'm a happy bunny. Its a horrible thing to have to take and its a life sentance but if you weigh up the pros & cons my experience is that its worth taking the risk. For me, its meant having an almost normal quality of life and has made the management of the two incurable diseases bearable. Ohh and by the way, it has NOT affected my fertility at all ! | M | 39 | 7 years | 2/7/2006 | 5 | Psoriatic Arthritus | At first slight loss of hair and total loss of eyelashes (on one eye - very attractive!)stomach cramps occassionally but now take it at night which helps. Loss of sex drive and seem to be more forgetful. Feet and hands have improved drastically since taking it. | Was worried about taking it at first and it took about 6 months to see real improvement but its worth the side effects it just to be able to dance again. | F | 49 | 3 years | 1/19/2006 | 5 | psoriatic arthritis | Head-ache the day after taking my weekly 15mg dose. Fatigue, but that could be due to recent weight gain from prednisone. I am off the prednisone now...yeah! | Has worked wonderfully for me. My psoriasis is totally clear for the first time in 7 years. My arthritis is doing well...didn't know how much discomfort and stiffness I had until I had been on MTX for awhile. 1/9/06 | F | 50 | 4 months | 1/9/2006 | 5 | RA | extreme fatigue on day of dose; slight nausea for 1-2 days after dose | I've only just started it and already my RA is MUCH better. I can lift my kids again, have more energy during the work week, and my pain is dramatically improved. I was able to stop taking prednisone this week because I feel so much better. | F | 29 | 3 weeks | 10/22/2005 | 5 | rheumatoid arthritis | When taking it during the day I felt nausea but since taking it before bed, I am fine. I get mouth sores but since being prescribed folic acid, that has cut right down. | I call it "magic". I have been on it for about 18 years and if I wasn't on methotrexate, I would have been in a wheel chair years ago. I am still working full time and rarely have any pain, swelling, etc. | F | 62 | 18 years | 10/2/2005 | 5 | Psoriatic Arthiritis | None apart from raise liver thingys. | I take Meth and Enbrel and it is a miracle combinaiton. My Psoriatic patches dissapear back into the woodwork, and the pain is gone like a wild goose in winter! | M | 70 | 2 years | 7/25/2005 |