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Drug Ratings for BENADRYL

Average Rating: 3.1 (467 Ratings)


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Results are sorted by length of time drug was taken from shortest to longest (with no time reported listed first)    

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)   

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RATING  REASONSIDE EFFECTS FOR BENADRYLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
sort down sort up F  M  
 3  Hives OMG! This was horrible at first. I've got a IV with Benadryl last night at the ER for hives. I felt it istantly. My body got hot and numb all over. I was so dizzy, and had speech problems. I've also had hallucinations. I saw stuff that wasn't even there. After a while I got used to it, and felt very, very sleepy. It wouldn't have been so bad if I had a little warning from the nurse, on how it effects people. At first I was certain, I was gonna die right then and there. M 34 1 days
6/10/2003
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 3  Blood transfusion allergic reaction The side effects were frightening to my mother who thought she was losing her mind. Her breathing was shallow and her hands and arms had tremors and involuntary repetitive motion. Easily could have confused this behavior with a stroke. My mother fought the effects of the drug by having me talk through all events of her stay in the hospital until she could fix them in her mind. At first she was unable to distinguish the difference between what she had dreamed while under the influence of bendadryl and what actually happended. F 85 1 days
3/28/2003

 3  Sinus infection BEWARE: the dosage is 2 tablets, but that dosage put me into a STUPOR. Take one only, and definietely don't take any before driving a vechicle. An ENT explained to me that this medication works by drying out the sinuses, and the "cure" is to loosen up the congestion. So: back to chicken soup and cocoa. F 50 1 days
4/23/2007

 3  For last 3 months for sleep Bad head aches and cold spots on my body F 62 1 days
25 mg
1/26/2012

 3  Extremely Itchy Tired, but can't sleep. Unexplained laughing M 15 1 days
50mg
11/27/2011

 3  Medical Exam All kinds of stuff. Immediate drowsiness, dizziness, weird burning pain in throat etc. I was injected with Benadryl yesterday afternoon for a medical exam and when I was injected with it I felt it immediately. My throat first started to hurt and then I felt drowsy and dizzy. My speech was terrible and so was my thought process. After my exam I went home and I know I talked to a few people on the phone but it feels like it was a dream. I slept for a few hours when I got home but woke up to eat dinner. When I woke up I felt disorientated and dizzy. Fast forward to the next morning and I still feel disoriented, drowsy, dizzy with a little bit of memory problems and the feeling of walking on air. I drove to work this morning and I had to recall if the stop light that I went through was red or green. NOT GOOD. This is a hardcore medication that needs to be taken lightly if you decide to take it or if administered at a hospital ask for a small dosage. Since mine was infused into me for a medical exam but I'd prefer Benadryl over Versed or some other drug that has long term side effects. M 28 1 days
Not sure 1X D
9/15/2010

 3  IV Predmedication about ten minutes after getting benadryl through the IV as a premed, I experienced dizzyness, eyesight problems, sleepyness, nausia and short temper (due to groggyness). This was the other option instead of IV steroids. I'm not sure I'd recommend it over solumedrol, especially since it's been linked to alztimers disease. F 23 1 days
2/1/2005

 3  Itchy Red Skin Spots, Eyes itching The effects have cleared up my skin and reduced itching. I took it last night for the first time at around 9pm. It is current 2:02 pm. I believe it is the after effects i am feeling now. Lethargic and in a daze. I think it is a great allergy medicine.On the other side This Inability to focus is nothing short of annoying. I am tired and I feel like im in a constant daze without being able to completely wake up or get eyes able to focus. M 24 1 days
5/18/2007

 3  was giving as an antidote for iron blood pressure elevated, felt like was not me, very tired stomachache it was giving as an antidote for iron infusion that gave me an allergic reaction F 33 1 days
12/20/2007
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 3  allergic rhinitis muscle twitching in legs at night, and have had muscle twitching in neck like a "tic" for YEARS after taking this medication F 45 1 days
1/17/2010
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 2  Bug bite on eyelid Drowsiness. Mild buzz. Benadryl didn't reduce the swelling. I've never found Benadryl to be very good. Reactine works much better for me. F 50 1 days
10/15/2007

 2  insomnia drowsy, vertigo, short of breath, severe aching and heaviness in elbows and arms and hands, agitated; fatigue and trouble concentrating the next day. I've taken a half dose of benadryl 4-5 nights/year for insomnia for about 10 years. Feel like a zombie most of the next day, so I only use it when desperate. Last night had new, awful side-effects: couldn't breath well, room spinning, heavy achy elbows & arms, physically agitated. Anyone experience those effects? Also taking 100mg 5-L-tryptophan (2 months) for insomnia. Must have been an interaction. F 50 1 days
9/25/2007

 2  insomnia, hives Rather than making me sleepy, I became listless while lying in bed, and my itching actually got worse! How odd. Darn, Benadryl is so well known for knocking you out, I had hoped to switch to using it for both needs, rather than the Claritin I use for the itching and Xanax for the insomnia, as I have been. (The Xanax is not working well for me either lately, which is why I was looking for another solution.) F 46 1 days
2/23/2009

 2  Seasonal allergies Nausea and loss of appetite. Dizziness, fatigue and slight anxiety. F 28 1 days
9/15/2008

 2  To relieve allergy symptoms Relieved allergy symptoms almost immediatly, then made me very sleepy. Went to bed.. and about 2 hours later wake up feeling extremely restless.. Almost like growing pains, needing to stretch every muscle in my body and unable to sit still for more then 5 seconds. Kept me up half the night. M 20 1 days
1X D
5/16/2011
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 2  Allergies Memory Loss, severe fogginess This is the only drug that helps my allergies, but it also erases my memory. I always kind of knew I was foggy while on it, but I didn't realize how severe the memory loss was until today when I discussed all the things my wife and I talked about yesterday, and I can't remember any of them. I will never take it again. M 34 1 days
1 pink tab 1X D
3/29/2010

 2  Allergic reaction to a mosquito bit Zonked out 2 hours after at 6.30pm until 5am. Feel tense on waking My mosquito bite went down a bit. F 40 1 days
7/20/2001

 2  severe contact dermatitis Severe drowsiness, lethargy, felt dazed, with a mild spurt of panic/anxiety (that lasted maybe 15 min). Started approx 1 hour after initial dose, lasted for 24+ hours. Had a severe dermal allergic reaction, took 2 25MG pills at 8pm. Was severely "out of it" by 9pm. Took another single pill at midnight before sleeping to try to reduce the itch/spread of my rash/hives. Was very dazed, and lethargic the whole next day - wouldn't have driven a car for sure. Did nothing for my rash. M 35 1 days
25MG 2X D
9/23/2010

 2  sinus head ache I took the benadryl for a sinus headache and about 10 minutes later i started shaking and my heart was raising! my heart felt like it was going to pound out of my chest! I had to pee ALOT! i called 911 because i thought i was allergic to it! but they told me it was just a panic attack! and now Ive devloped a fear of eating because im scared im going to have a reaction and have to take another benadryl!! does anyone have any advise for me? F 21 1 days
1X AN
7/19/2010
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 2  Hay fever I took two tablets tonight and that was a mistake! I have been up since 3am with the inability to urinate, but have an intense feeling of having to. It feels like my urethra is swollen shut. I have not left the commode for over an hour because of the pain. I can go a few drops at a time. I have never had trouble in the past, but after last night I will never try this medicine again. F 40 1 days
50mg 1X D
8/8/2011

 2  Bad allergic reaction Rashed out extremely bad after taking other Pill, went to ER and nurse gave me 50g of Benedryl. Rash went away almost completely within half hour and was told to take 2 more every 8 hours today. Took my next 50mg at 6pm, got super drowsy and a bit irritable, so so SO tired but everytime I lay down and close my eyes my heart races and I jump awake trying to catch my breath. Had same problem when given demorhal while in labour. Cold and jittery, dry eyes and throat. Feelings of Rashing out again. Blah ! Terrible and scary feeling. Just want to sleep! Never again! F 22 1 days
2 x 50mg
3/18/2012

 2  Allergies My legs start feeling weak, then my head seems foggy. I have to lay down. I feel the medicine moving through my body, causing me to feel numb in certain areas. Hot/cold spells. It last for a few hours after taking the medicine. It freaks me out. I am sure that Benadryl works fine for most people. My first bad experience was when I was 4 months pregnant with my middle child. I went to the hospital with extreme nausea/vomiting. They gave me Benadryl. I immediately began feeling that heaviness in my legs, the tinglyness, then numbness. I had to be immediately wheeled to a room because I couldn't even sit up straight in the chair. It was very scary. Thought it was because I was pregnant. Nope. I get this same reaction when not pregnant and even when only using the cream. Will never use it again. F 22 1 days
1X D
5/11/2012

 2  Hay Fever Extreme tiredness and fatigue. Light-head and loss of concentration for over 24 hours. The tiredness and fatigue and light-head lasted for more than 24 hours after taking a table to relieve hay fever symptoms. I have found other antihistamines much more effective and without the unpleasant side-effects that I experienced after taking Benadryl. M 34 1 days
6/28/2004

 2  Allergies Insomnia, tenseness I'll never take it agains too many bad sideaffects for me. M 26 1 days
4/24/2002

 1  Contact dermatitis - itching I had a paradoxical adverse reaction from Benadryl which caused my throat to start closing up. In trying to keep my breathing passage open, I started hyperventilating. My wife called 911 & I was taken to hospital w/ oxygen. I was given Adavan (Ativan?) to relax my muscles & help regulate the pace of my breathing. ER Doctor gave me prescription for Zentec (low-sedating antihistamine) to use for the itching instead. I don't know of anyone else who has experienced this unusual reaction, but I think it's good for people to know that this adverse reaction is possible. M 42 1 days
1/4/2005
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 1  Allergic rash I had involuntary body motion. My hand kept flinging out as I was about to fall asleep. I could not sleep until the medication had worn off. F 54 1 days
9/28/2002

 1  Allergic rash I had involuntary body motion. My hand kept flinging out as I was about to fall asleep. I could not sleep until the medication had worn off. F 54 1 days
9/28/2002

 1  insect bite Very drowsy about 1 hour after, which was expected. It did help with the swelling and itch. However, I was extreemely fatigued for more than 24 hours, difficulty thinking, speaking clearly, and making descisions. I am scared to take Benedryl ever again! F 33 1 days
5/17/2003

 1  Stuffy nose I only took it once about 1/2 hour before going to bed. As I was in that halfway point between sleep and being awake. I felt like an explosion in my head. There was a bright light and I jerked myself awake. I don't know if it was the Benadryl or not but I think it was. It freaked me out so much that I can't get back to sleep and will probably not sleep at all tonight for fear of having it happen again. I peed a lot tonight and have a very dry mouth. M 55 1 days
1/3/2006
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 1  insomnia I had to pee all night and after a few weeks I began needing to take more and more to have it work for sleep. I will take a box of it and sleep on the toilet...or wear a diaper just so I can sleep. Gosh...sometimes life is a bummer! I have Crohns disease as well as Fibromyalgia and a few other fun stuff. F 54 1 days
3/28/2006
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 1  Hayfever, Insomnia In-effects: congestion, restlessness, insomnia, much urination Do not experiment with new medications before final exams, but at least I finished my paper at 4:00 AM. M 25 1 days
4/25/2006

 1  Allergic reaction (itchiness) Difficulty breathing; anxiety; panic attack; nausea; difficulty swallowing; drowsiness; burning sensation in chest. The feelings were very intense and scary. I felt like I was suffocating and wanted to scream. I received it thru IV before a platelet transfusion.. F 27 1 days
25 mg 1X D
12/10/2012
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 1  Shot thre IV before ct scan Felt hot,dizzy,lightheaded,tired,almost passed out,weak M 21 1 days
10/24/2012
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 1  With toradol Hot flashes, out of body experience, anxiety F 22 1 days
IV
5/14/2013

 1  Help with sleeplisness Wired and shaky, inability to urinate and mental confusion F 30 1 days
12/8/2005

 1  Sickness The shakes, nervous, sick to the stomach, hot and cold flashes, awake and tired at the same time I've been having the shakes for 3 days if you want to take Benadryl I recommend caution. M 18 1 days
3/12/2006
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 1  Prevent Reaction from CAT scan dye Was given to me through iv port in my hand last night prior to a cat scan. First it burned like heck and I asked the nurse to slow it down got red streaks going up my hand from injec site, immediately began to feel utterly weak, shaky, like lights were too bright, voices too loud, I couldn't form a coherent thought, my Dr and nurse thought I was crazy/couldn't believe I would have this reaction. I was shaking and my muscles wouldn't move, I could not speak this lasted for about an hour. It is now 12 hours since my er visit and Im still not 100%. NEVER AGAIN F 55 1 days
50mg IV 1X D
3/12/2011

 1  rash, hives 4 hours after taking 1 tsp of the liquid children's version, I woke with extreme thirst, went for water, and blacked out. Woke up in a pool of blood, 2 black eyes, cut, sore ribs. i am 61 years old, 165 lbs, female. Dangerous Drug F 61 1 days
12.5mg 2X D
9/30/2011
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 1  To sleep Headache, nausea, irritability, anxiety, restless legs, increased heart rate and increased blood pressure. F 32 1 days
50mg
12/29/2011

 1  Given in the ER I was sick and went to the ER for heart problems. I do have tachycardia as is, but they thought the benadryl would help calm me down. It sped up my heart rate from 120 to 200 bpms. I was terrified and they had to give me two other medications on top of it to try and calm my heart down. F 26 1 days
25mg 1X D
3/14/2012
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 1  Sleep aid Extreme grogginess but couldn't sleep, dizzy, heavy breathing, dry mouth/throat. Finally waited it out or so I thought after 4 hours slept for 2 woke up groggy again. When trying to go back to sleep had very weird almost like electrical surges in nervous system made me stay up and come too before trying to sleep again. Now writing this hope I don't have issues when trying to sleep again. Gonna have someone watch me as I sleep if I can. M 29 1 days
25mg
2/1/2012

 1  Sleep Aid For years, I have taken Benadryl as a sleep aid. Not often, just on those occasions where I know I need sleep and want to get to bed ridiculously early. I have never experienced any adverse side effects, other than occasionally being drowsy the next day. Well, first time for everything - last night, I experienced as close to an anxiety attack as I have every felt after taking the drug. My heart was racing, I was freezing cold yet sweating profusely, random muscle twitching, all shaky, felt all paranoid, and most CERTAINLY sleep was no where in sight. This lasted for about 4 hours, maybe more. I woke up and the feelings were gone, but I feel very off today, tired, sore, mind feels very groggy. Up to this point, I would have given a 5 based on the sedative effects of Benydryl. It used to put me to sleep within a hour of taking it, and I would sleep well. But after my most recent terrifying experience, I cannot under any circumstance recommend this drug. M 34 1 days
50MG 1X D
1/12/2012
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 1  migraine and nausea felt my throat and nostrils were burning. Two minutes after the shot (at the emergency room), I felt extremely drowsy but could not sleep. Five minutes later, I started having a panic attack, worse feeling ever. I wanted to run, to escape. It was a nightmare! I tried to relax, but apparently fell unconscious. The hospital nurses found me on the floor. I had a bruised knee, sore upper back muscles, and I also hit my head. It took me three hours before I could go to sleep because of paranoia. The next day, I still feel groggy, burned nostrils, but unable to sleep. F 30 1 days
20 1X D
3/1/2012
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 1  Nausea & Allergies Extreme anxiety I am pregnant and one of my choices for the nausea was Benadryl. Considering nothing else worked, I gave it a try and will never take it again. About 30 minutes after taking it, I went into full panic mode, sweating, racing thoughts, fast heartbeat, and shaking. I dealt with panic attacks a year or so ago so I recognized what I was dealing with, even having not had a full blown panic attack in a year. I know for a fact that it was the Benadryl that caused the panic attack. Luckily, it went away after about an hour but that was a rough hour. I remember taking Benadryl a few years back as well, and it did the same thing-I just didn't know what a panic attack was at that time. If you're taking it for allergies, go to a doctor and get a prescription for something. Most of the over the counter allergy medicines have this effect on me. However, most prescriptions I've taken do not. F 26 1 days
25 mg 1X D
7/20/2010

 1  Itchy eyes Burning in lung and throat and hoarseness. Will not take again. F 55 1 days
1 tablet 1X D
9/21/2010

 1  To sleep I get headaches and I had one and could not sleep. I was afraid if I did not sleep the headach would be worse so I took a nighttime sleep aid with acetominophen and benadryl. I went to sleep but then was feeling very drowsy and in a fog the whole next day. Also had some nausea. Could concentrate on any task. I did not get out of bed the whole day and was never so tired and drowsy ever. I can only relate it to the benadryl. I will never take benadryl again. F 41 1 days
50mg 1X D
8/27/2010

 1  Common Cold Heart racing to the point where it was 40-50 bpm faster than normal that woke me in the middle of the night after taking the third dosage for the day; excitability and inability to sleep longer than 8 minutes; extremely cold feet and hands; dry heaves and diarrhea After having used Benadryl numerous times over the years, a dosage taken at 10:30 p.m. caused me to awake with my heart racing at 1:30 a.m. to the point where I called poison control who said a single dosage could not be causing the problems I was experiencing. Within seconds of waking up I realized my hands and feet were ice cold even though I was tucked into flannel sheets and usually have my feet too warm during the night. A few minutes later I was dry heaving and had sever diarrhea. The problem was so severe I had to seek medical treatment to check on my heart. Fortunately no damage was done but I will not be using this medication again. F 35 1 days
25mg 3X D
2/22/2010
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 1  pregnant w/ allergies I had hallucinations... they were so bad. Jittery, cotton mouth... When you are pregnant with bad allergies, the only thing you are recomended to take is benadryl and they are rough. F 26 1 days
1/28/2010

 1  Itching After 8 hours on this drug, I am still in a deep fog. I can't get clear-headed. It's scary and annoying. I haven't gotten anything done all day. F 58 1 days
1/2 25mg 1X D
3/16/2010


History
 1  Migraine They gave me a shot of this with reglen and I became very parnoid. My anxiety was insane I seriously felt like I was losing my mind suicidal thoughts and didnt want to hear any noise at all. I willnever ever ever take that again ever I warn people be very careful with this stuff. To who thinks we are hypocondriacs how can you say how it makes you feel should make everyone else feel the same everyone is different it might be great for some and horrible for others like me. F 30 1 days
dont know 1X D
7/19/2011
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 1  nausea Was given it while in the hospital by IV. Immediately caused a severe panic attack- I was fine until they gave me the med. I felt like I couldn't breathe, and I started moving my legs uncontrollably. Horribly afraid even though I knew nothing was wrong. The nurse had to come back in and sedate me. NEVER AGAIN F 23 1 days
? 1X O
5/29/2011

 1  runny nose, itchy eyes, allergies Benadryl causes nightmares, big time. Yikes. It's 3:49am and I just found this website via Google after waking up with night terrors. I'm glad I'm not alone, this information is all over the web. This wasn't the first time either with Benadryl. We have to get the word out, I've read on several other websites this is used as a cure for night terrors when it is really the cause! M 42 1 days
30mg 1X D
12/25/2010

 1  insomnia insomnia! Took for insomnia and ironically kept me up the entire night. F 37 1 days
50 mg 1X D
1/4/2011

 1  For extreme itching/hives Dizziness, agitation, feeling as if my heart was beating out of my chest, paranoia, anxiety, tired but not being able to fall asleep. I took a 3 tsp children's dose at 6pm as directed by my MD. Felt dizzy so I stayed in bed. Got up to take my second dose at midnight since I was still itching. Couldn't fall asleep. Got up again at 5:30am to drink water to see if it would help my agitated state. As I was walking back to my bedroom, things appeared dark and I had ringing in my ears. I passed out in front of my bedroom window, breaking the fall with my chin and teeth. Was rushed to the hospital by ambulance. I was conscious and able to respond. Plastic surgery and a good dentist are working to put me back together. I will never take Benadryl again. F 49 1 days
5/20/2009

 1  Allergic reaction to Chocolate This was horrid but not the fault of Benadryl. I was rushed to the hospital for anaphylactic shock due to accident ingestion of chocolate which I am highly allergic to. They gave me Epinephrin immediately and the swelling in my throat started to go down, then they gave me an injection of Benadryl in my IV and within 5 minutes, I was in worse shape than ever. I vomitted, aspirated and needed to be intubated to save my airway. After about 2 hours, I was finally able to have the breathing tube removed as they THOUGHT that the chocolate was still the cause of the shock. About an hour later, they gave me another injection of Benadryl in my IV and again, within 5 minutes... I had vomitted and was again in Anaphylactic Shock. They finally figured out that NOT only am I allergic to the Chocolate (which really stinks because I do LOVE it) but I am also HIGHLY allergic to Benadryl. I think this is a great medication for those who can safely take it as it CAN save your life in the event of a severe allergic reaction such as I had to Chocolate. Unfortunately, Benadryl nearly cost me my life. Luckily, I happened to be in the hospital when the reaction occured and I truly believe this is a miracle! F 40 1 days
6/1/2009

 1  fluid in ears tinnitus...terrible screeching noise in both ears. Restlessness. Agitation. Stopped when I stopped taking it. F 40 1 days
2/11/2009

 1  Headache/Sleep Aide Took 25mg Tylenol PM (Diphenhydramine hydrochloride(HCL))at bedtime for headache/sleep aide. NOT KNOWING IT WAS RELATED TO BENEDRYL. After about 3 hours, I woke up with ringing of ears, feeling like my eyes were dilated (but were constricted instead), had dry mouth. I became cold & clammy, dizzy, my eyes started to black out(go fuzzy), felt like I was floating off the ground. Ran for the couch and collapsed..feeling weak, heaviness (unable to move like I was paralyzed)I could think but not speak to call out for help. I had shortness of breath and difficulty breathing. I started sweating profusely, feeling panicky. I was so scared. Finally fell asleep (against my wishes). Woke up still feeling weak, drowsy, fatigued, irritable, panicky, still had dry mouth and depressed. The medical staff seemed surprised that I would be allergic to Benadryl, also ALOE VERA, of all things. As I read this website, I know now that I'm NOT alone. After that horrible episode, many years ago, I REFUSE to take Benadryl or anything that has Diphenhydramine hydrochloride (HCL)in it. I have to check the ingredients before taking anything. I don't take any kind of medication unless I absolutely have to. F 48 1 days
2/27/2008

 1  Poison Ivy sedation, depression, anxiety, rapid heartbeat, chills, lack of control of body movement, comatose, extremely tired when I eventually woke up. I felt like I had no control when the sleepiness abruptly set in about an hour and half after taking it. I was so cold and could not get my body to warm up. I became irritable and struggled with rapid heartbeats while I was asleep. I felt like my body wanted to get up but just couldn't (comatose). The next day I experienced anger, depression, fatigue and guilt for no apparent reason other than the benadryl. F 22 1 days
5/4/2007

 1  allergy Loss of body and mind control. Shaky and confused. Resulted in what I could only explain as a panic attack. Took 50mg in the morning for a cat allergy after a night of heavy drinking. I don't know if this reaction was only due to my already fragile state but I'm not scared easily and this was the strangest thing that ever happened to me(freaked me out.) I would recommend not taking on a sever hangover. M 29 1 days
2/15/2007

 1  allergic reaction Restless, jumpy, kept actually leaping out of bed uncontrolably, my legs would thrash like they were trying to get something out them, agitated because I was SO tired but couldn't stop thrashing about, I would start to fall asleep then all of a sudden....thrash, my heart felt like it was pounding hard, my body hurt, I was crying and screaming. it was like I had all this energy and my body thought if I just kept moving it would go away. My mother told me that I was given this as a child but I had a bad reaction, I am 26 now and have never had to take other than the time my mom gave it to me and I don't have any memory of that event. Last month I had a dystonic reaction to phenergan, (anti-nausea medication, supposively it is a rare reaction, in which I had no control over my body, it was alot like the benadryl reaction only on a super scale, very scary) The doctors told my husband that the treatment is usually benadryl, because it wasn't listed in my charts at the ER as an allergy and because I could not make decisions for myself and was completely out of it he had to make the decision to approve the benadryl, unknowing of its reaction to my body. I have never felt worse in my life, the benadryl alone is horrible but the dystonic reaction, I wouldn't even wish for my worse enemy. after they administered benadryl they quickly found out its reaction and gave me a big shot of ativan and continued giving me more until I f F 26 1 days
12/1/2007
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