BENADRYL Reviews (DIPHENHYDRAMINE HYDROCHLORIDE)

Average Rating: 2.9 (608 Ratings)

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 Type: Rx to OTC Drug

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on BENADRYL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR BENADRYLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Allergies Like tye perdon above, I too had the crawling sensations and it was bad. I thought I had some bed bug or mite, but I after tearing apart my bed and washing sheets, I realized it was the Benedryl doing it. I hate it 3 days
50 mg
6/1/2014
 4  ear pain and difficulty hearing Extreme restlessness, inability to sleep F 63 1 days
3O MG
5/25/2014
 1  Allergies Restless legs, nightmares, fatigue next day I took this for about 4-5 days in a row for allergies because my nose gets stuffed up when I try to sleep. It gave me really bad restless legs, it did help me sleep better but I had nightmares, and it made me very tired the following days after taking it (one 30 mg dose before bed). I also noticed my allergies seemed a lot worse the following day(s), headache, sinus, dry eyes - but one kept watering for hours, and I felt almost depressed. I also woke with ear pain and could feel liquid in my ears about to come out when I'd wake up. I think it was draining my sinuses at night (so clearing my nose so I could breath) but the drainage was causing other problems. I usually take nothing for my allergies and now I remember why. I won't be taking this anymore. Maybe I'll try some natural remedies if needed, occasionally. F 45 5 days
30 mg 1X day
5/9/2014
 1  Insomnia I have been taking diphenhydramine for years with no serious problems. However, as I got more dependent on the drug and built up more intolerance I needed to take more for the drowsy effects to work. There's a reason the bottle advises AGAINGST taking it long term! I have OCD and it made my anxiety and OCD worse; I started hallucinating transparent spiders (once hallucinated rats and scorpions that looked real); restless legs; itchy; violent thoughts and urges about others. I have decided to quit taking this after the latest violent though side effect. Not worth it. A few times I had a sense of impending doom and feared that I was going to have a heart attack or die in my sleep. Definitely increases depression beyond "normal" levels as well as suicidal thoughts. Occasionally I l also had short term amnesia that lasted until the next day (forgetting words, not remembering what I was going to do next.) please do not abuse this drug! You don't want to end up hurting yourself or others and the paranoia and constant fear of dying is totally not worth it. It's best to speak with your doctor; although all meds have side effects you've got to decide if the results outweigh the bad. I used to think they did for me with this drug but now don't. F 25 6 years
500
4/16/2014
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 4  Allergies After 4 days of regular usage I had a dizzy spell which was almost enough to make me fall down. It lasted 5 seconds or so. A few hours later I was driving on the interstate and had an INTENSE dizzy spell lasting about 20 seconds. My vision was severely blurred and I could not mentally focus on anything around me. Thank God I was on a straight track of road with little traffic. There is no way I could have made a turn or even pulled over to the side without wrecking. I was a little dizzy for the rest of the day but otherwise fine. VERY scary! Works great for my allergies. I had never had a problem before but had never taken it that regularly (keeping it in my system) for several days like that. I was taking one 25mg in the morning and one in the evening as 2 pills at once tends to make me very sleepy. M 37 4 days
25 2X day
4/14/2014
Email
 2  Sleep Aid I took Zzzquil (same active ingredient - diphenhydramine) and it knocked me out at about 10:00PM. I woke up at 2:30AM in a panic, severe anxiety, racing heartbeat. It was terrible! Now I realized I get an adverse reaction to this drug, as I've experience the same with Tylenol PM. I did not think that such a common, OTC drug could cause such and adverse reaction. I don't suffer from anxiety normally and I don't take any other medications. M 26 3 days
50MG 1X day
3/12/2014
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 1  For cold symptoms I had been on benadryl for about my third day. Took it around 11pm and woke up around 1 am feeling like I could not breathe. I was shaking all over and could hardly catch my breath. I had to focus on breathing slowly as I drove myself to the ER. I shook all over and had a rapid heart and elevated BP for about 3 hours. I was given xanax and told to NEVER take benadryl again. The xanax helped as did drinking lots of water to flush the benadryl out. I looked pale but finally made it through, exhausted! Deep breathe slowly if you have a reaction and get to the ER. My throat was so dry it's like it was closing up. F 41 3 days
25mg 1X day
2/19/2014
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 4  Itching Cramping in legs ..stomach cramping F 46 3 days
25 mg
2/17/2014
 1  insomnia restless legs, extreme nausea and anxiety, insomnia, rapid heart rate, tinnitus, anger and panic. All which lasted for days. F 29 3 days
50 mg
1/22/2014
 1  to help me get to sleep Whole body twitching,muscle aches,cramps in calves anxiety constant urination panic attacks...I thought I was dying....depression...been off it 5 days now. Symptoms are getting better but still groggy...I will never touch this med ever again. It is dangerous and nowhere in the info does it say this can happen F 42 10 months
50mg
1/16/2014
 3  Sleep aid and allergies. Causes GERD to worsen with heavy chest pressure, discomfort, palpitations, shortness of breath. Nightmares. Strange sensations in feet and legs. Tingly ring and pinky finger. Back pain near shoulder blade. F 53 3 months
25mg
1/1/2014
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 5   1 days
11/17/2013
 4  allergy attacks/ sleep aid I first starting taking it for allergy attacks w hives, rash, facial swelling and it works great and fast. I''ve also been working nights for about 7 years so my sleep is off. It works well for insomnia knocks you.out it does loose its potency after a while and your sleep is not as deep... but if your to the point where 50-75mgs doesn't work than its time to look into other options/solutions. After a few weeks I stop taking it for a week or so to give my body a break. But I''ve had no negative side effects. F 26 1 years
50mg
11/6/2013
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 3  allergic reaction to bee sting Extremely sleepy blurred vision and two days later still having dizziness when i lay down or move my head to get comfortable.. literally feels like the room is taking off... F 36 1 days
two
9/5/2013
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 1  Allergies Out of body experience, delayed movements, weakness, dizziness, panic attacks, increase in deppression F 16 3 days
25 MG 1X day
8/30/2013
 1  Nighttime sleep aid Horrible anxiety attack. Throat went numb then spread throughout my body. Electrical surges. Felt like I was going to forget to breathe. Out of body experience. Thought I was going to die. I will never take this again. F 53 1 days
30 1X day
8/21/2013
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 5  Sleep Aid None. Drowsiness. I started with 2 - 25mg pills, then went down to 1. I know only use 1/2 a pill at 12.5mg and it works well. M 42 4 years
12.5 1X W
8/18/2013
 1  Cold/ sleep aid Bradycardia (very low pulse) chest pressure, head pressure, extreme anxiety, panic attack, restless legs, and it made the insomnia worse. I had been suffering from a cold and insomnia so I took the recommended dosage of Benadryl. Had taken it in the past and it didn't seem to be a problem. This time was different. My pulse which is usually on the fast side, slowed way down. I felt dizzy and anxious and 10x worse than before I took it. I will never take it again. I'd rather be sick and not sleep then go through this nightmare! F 34 2 days
2
8/6/2013
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 1  sneezy Twitchy kind of like anxious.keept me awake.took them for years but now i seem to be alergic? 57 3 days
25mg
7/19/2013
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 4  Allergies Hive's if taken alone with out IB, headache in the morning, Foggy brain with memory loss, Itching at times, heavy legs. and numbness through out the body. Both side of my neck felt swollen also when I wake up. I did not know it was the drug until I stopped everything else I took at night. I had numbness in my head and throat and heaviness or swelling in the sides of my neck and then it started to spread through out my body. Unless I take IB with it I wake up with pain in my arms and legs. Foggy brain is really bad with this drug and so is memory loss. I going to try and stop this drug wish I had figured this out sooner. I also have no sex drive and this has been going on for years. F 51 8 years
1X day
6/26/2013
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