There are 290 ratings for the drug: PREMARIN in the Askapatient database.

Key to ratings for premarin: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine.

Page: 1  2 3    Results are sorted by Satisfaction from highest to lowest.

Rating	Reason	Side Effects	Comments	Sex	Age	Time Taken and Dosage		Date Added
				F  M
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5	complete hysterectomy	NONE,that I am aware of.	Recently I had to have a breast biopsy, and I was told to stop taking my premarin. I did. It was not cancer, we were blessed but when I wanted to go back on my Premarin, my Dr. suggested not doing so,because I had taken it for so long. I felt so good when I took it. I did not feel as tired, I had energy. I have lost a very few pounds since I have been off the medication but I believe I could manage those pounds. My joints were more flexible when taking Premarin. Now, I get no sleep,the hot flashes are unbearable, the heart palpitations are common. I just really will talk to my Dr. at this point about a dosage every other day possibly. I have been off Premarin for over 90 days and I feel like I am older than 65, I want it back. Recently I bought Black Cohosh to maybe help. I had more problems with that over the counter supplement than I ever had with Premarin.	F	65	22 years .065 1X D		8/23/2010 Email
5	hot flashes	No side effects that I know of, been taking it for over 10 years, but I now have high blood pressure and thyroid issues. I have decided to stop taking it cold turkey, any suggestions from anyone if this is ok.	No side effects that I know of, been taking it for over 10 years, but I now have high blood pressure and thyroid issues. I have decided to stop taking it cold turkey, any suggestions from anyone if this is ok.	F	52	10 years .09 1X D		6/5/2010 Email
5	Complete hysterectomy at age 33	No side effects attributed to Premarin	At the urging of my family doctor, I decreased my dosage to .9 and two years ago to .625. I haven't had problems with hot flashes, sleeping, weeping episodes, etc. My bone density is great, my skin good, and people don't believe my age. My GYN is OK with my taking Premarin. I'm scheduled for a total knee replacement in just over three weeks, and earlier this week, the orthopoedic surgeon told me that I had to stop the Premarin immediately. Cold turkey. Today is day two. I have very stressful circumstances in my life, so the thought of adding more is somewhat frightening. However, it pales in comparison to the potential of a blood clot after surgery. It's something I must do. I do have the option of going back on it later on if it gets too bad. Who knows? I pray for strength during this time and wisdom to know what to do later on.	F	67	30 years .625 1X D		6/4/2010 Email
5	Complete Hysterectomy		I was put on 1.25 mg the day after my hysterectomy. along with 60 mg of Armour Thyroid. After some minor adjustments, my body accepted the doseage. Two years ago, I was advised to lower the dosage to .625 mg and recently my new Gyn advised me to wean myself off, due to the chance of cancer, etc. Since May 5, 2010, I have been taking .625 mg every other day. I have started to have aches in my body and symptoms of like the start of a leg cramp, plus a couple of real good HOT FLASHES. Which I never had had. My Gyn advised that it could take a couple of years for my body to rid it self of the build up I have and to just adjust my doseage as my body gets use to the lower dose. Any suggestions or other views is appreciated.	F	59	24 years 1.25/.625 1X D		5/19/2010
5	Radical Hysterectomy	NONE (now) - started w/ low dose & had hot flashes galore, headaches, bad mood, depression, weight gain!!! At 40!Increased the dose = magic!	I love it. After the surgery went on low dose(always best) but it just didn't cut it. I have taken .9 for 4 1/2 years now & wouldn't stop for anything. Went out of town w/o it once- NEVER do that again (even my husband asks if I packed it!) I will say this- I was worried about the HAIR LOSS thing, about 6 mo's ago mine started to thin big time! My doc said it's unlikely the Prem since I've been on it so long...after seeing specialist & doing test, finally discovered it was my husbands fault!!! Really!! (not the stress) But he started using an external Rx testosterone gel (his levels were low)and it was getting transfered on to ME! = hair loss. Momma not happy.	F	44	5 years .9 1X D		4/22/2010 Email
5	hysterectomy	None	I have been taking Premarin for 13 years and have always felt fine. I have to buy it on internet now as GP won't supply it. After 6 years I started having panic attacks and developed high blood pressure.I don't think they are connected but maybe they are? I would like to stop in 2 years when I am 65 but I am worried I will suddenly feel old.	F	63	0.625 1X D		4/15/2010 Email
5	MENOPAUSE	WEIGHT GAIN	HAVE USED OTHER ESTROGENS BUT NONE HELP WITH MEMORY EXCEPT PREMARIN. HELP WITH WORD RETRIEVAL, ESPECIALLY.	F	51	365 days .9 1X D		4/7/2010
5	surgical menopause at 55yrs old.	After 4 months of 1.25 dose, cluster headaches and edema and high blood pressure.	Reduced to .625 for one month, headaches and edema gone but blurred vision, anxiety and dry skin. Increased to .9 and doing great. Taking BP meds for borderline high BP. Premarin does wonders for my cholesterol numbers, hair, skin and libido.	F	55	7 months .9 mg 1X D		3/27/2010
5	Hysterectomy	NONE	I have been taking premarin for 27years and would not stop taking it no matter what anyone said. I have tried to stop thru the years but it always ends up the same. I start having hot flashes, bad headaches & just feel miserable, so I always end up going back. I alway used 1.25 which is a very high strength in the last year or so I have cut back slowly to about 1/2 that amount, if I try to go any lower I start back with all the same symptoms. I have had a much better quality of life for taking it.	F	61	27 years 1.25 1X D		2/8/2010 Email
5	total hysterectomy	None except possible link to migraine headaches.	Since my hysterectomy, I have continuously been on Premarin 0.625 until three months ago, when I stopped due to possible link to migraine headaches. During that period, I have felt terrible, although my headaches lessened. It must be noted that I also STOPPED the use of my favorite food in the world, CHOCOLATE. Not sure which contributed most to the headaches being less, but the premarin cessation has caused sleeplessness, irritabilty, crying, loss of memory, depression, sense of impending doom,sweating, dry skin, lack of concentration and feeling like an old lady. Two days ago, my doctor recommended that I go back on the Premarin, which I did and noticed a dramatic change in all the above symptoms, especially the horrible hot flushes throughout the day. I will stay on this medication. Since I work in the medical profession, I am aware of the propaganda the drug companies produce (presented as education)to sell their wares. Do not believe everything you hear. Do research on it for YOURSELF. Everybody is different and everybody's BODY is different. No one can reliabibly predict side effects, since chemistry is too varied and individual. The side effects and disclaimers are simpley to protect the interest of the drug companines against laws suits. I encourage anyone taking Premarin to do research for themselves and listen to that inner voice about this medication. It's not for everyone, but it is for ME.	F	65	15 years		1/27/2010 Email
5	cancer related had a Hysterectomy	No side effects at all....if I go off the pills I feel horrible. I have been on premarin for 14yrs		F	47	14 years		12/11/2009
5	total hysterectomy	tried bioidentical because they were to be so much better not, after several months of chest pain ,heart palpatations, increased blood pressure and increased pulse rate I went back to Premarin and all those side effects went away, will not change again.	Do not be fooled by bioidenticals if you have any heart symptoms could be that. I have not had any problems since going back on Premarin.	F	41			11/22/2009
5	hysterectomy at 45	I've never had a side effect.	The doctor suggested I stop taking it and immediately felt horrible. I also gained 10 pounds & my blood pressure went up. I've never been on blood pressure medicine but now I am. I went back on premarin & now have a GYN appointment to fight for my right to remain on it. I know the risks but there are risks in everything - this works for me.	F	64	19 years		11/10/2009 Email
5	Total hysterectomy at age 26	I bled for 8 months straight. Very heavy with huge clots. None of the meds that was prescribed worked. I had to have everything removed except for one ovary. I went for 8 months not taking any kind of hormones. The doctors were hoping that my 1 ovary would kick in and work. But it did not. My body began to swell and just touching my body anywhere with the slightest pressure caused me great pain. I was then put on Premarin. The swelling went down, no more pain. I have been on it since 1986. My doctor wanted to lower my dosage. We did and all the pain and swelling came back! And we tried this over the years several times. Always came out the same with the same results...all BAD!. I told her that I will stay on it for life. I will not go through that again!!		F	49	23 days		10/10/2009 Email
5	Total hysterectomy at 39	I had no side effects and had taken it for 25 years! .065 dose. My doctor took me off of it about 1/1/2 years ago, as he said they believe it increases blood pressure. High blood pressure runs in my family anyway, but I do take medication for it, its borderline.Since stopping premarin, I have terrible hot flashes, hair loss and getting flabby around the middle, despite my working out, and more hair on my face. I am going back to the doctor tomorrow and want to go back on it.	I never gained weight from premarin and I am going back on it!!!!	F	66	25 years		9/8/2009
5	menapause/osteo	migraine, but this is genetic and based on the normal hormonal cycle anyway for members of my family. I had no side effects and felt wonderful. Full of beans, fit and healthy. Last year I did have abnormal cervical cells which were checked OK. Being checked again shortly. Just recently taken off premarin by doctor after increase in BP after heavy stress at workplace, and prescription availability problems on NHS. Put on Femoston. Suffered night leg cramps, aching, dizziness, dulling of brain, nearly had a road accident and I cannot sleep anymore because of the cramping of my legs, which also have sensations like insects crawling over my skin, and assorted sudden pains everywhere. I want my premarin back! I'm off to the doctors to sort things out.	Love it!	F	64	15 years		8/20/2009
5	Total hysterectomy age 44	Mostly side effects when I didn't take it. Intense crying episodes. I do have concerns about it with the breast cancer thing..but do not know of any negative side effects	Initially took 1.25 decreased to 1.0 & 6.0 over time now taking .3 every other day for 2 years.	F	68	20 years		4/26/2009 Email
5	hot flashes	none	I just afraid of the cancer threats with taking this medication.	F	55	4 years		3/30/2009
5	total hysterectomy	I gained weight on the 1.25 when my MD cut them in half to .6 I lost it right away. 5 yrs later my MD rotated me between .6 and .4 and I did that for a yr and now she's wanting me to take the .4 full time.	I agree- everyone says I have great skin- I think it's gebnetics tho' Polish/german both sides and my folks still lokk 50 and they are in their 70's	F	52	10 years		1/26/2009
5	Had a total hysterectomy	I don't believe I have had any negative side effects. I was told I would gain weight after my hysterectomy, and I am heavier then before the surgery and taking Premarin. However, I have been able to lose weight by following Jenny Craig, so I don't believe the weight gain is from either.	At age 40, I had a total hysterectomy (both ovaries and uterus)due to Endometreosis. After surgery, I was immediately given a hormone injection, then started taking Premarin. I often get compliments on my great skin and most think I am at least 10-yrs. younger then my 57 years. I do not have a history of breast cancer in my family, and watching my Mother develop a hump on her back by not taking any HRT after her menapause, I have made the concious decision to stay on Premarin 0.625 and have a great quality of life, unlike some of my friends who are scared to death to use it and suffering. In the end, it is a personal decision, everyone's bodies react differently to meds, and based on each individual's family history and life choice. One more plus, I have same libido as prior to surgery/Premarin and experience no vaginal dryness, so no need for vaginal creams, gels, etc.	F	57	18 years		1/21/2009
5	hot flashes, night sweats	None. Possibly big weightgain but who knows?	It's the PROVERA that's the poison; not this. The Womens' Health Initiative used Provera or Prempro. I take this ALONE and have 0% hot flashes. I cannot live without my sleep, period. Raising my grandson. First week of the month I stop.	F	64	20 years		12/1/2008
5	Symptons of Menopause	None yet.		F	54	5 days		11/19/2008
5	abnormal uterine bleeding	none	1 pill for 21 days each month.	F	48	3 months		10/25/2008
5	Menopause	None what so ever.	Doctor has me on .3 mg 25 days on, 5 days off. After one and one half month the hot flashes have disappeared and I can now get a full nights sleep. I no longer go from hot sweat to refrigerator with no in between. It was awful. I tried everything under the sun and got fed up. I had hyst. at 40, kept ovaries. The symptoms took 1 1/2 months to fully go away (you have to be patient). Still need the fan on sometimes. Do not need progesterone due to no uterus. Got three month supply through mail in with insurance coverage and costs $30 per month.	F	52	45 days		10/12/2008 Email
5	To stop menopause migraines at 45	I'm a DES daughter - had female problems all my life. Started getting terrible headaches at 45 -stress, divorce, weight gain etc. Doctor put me on highest dose Premarin. Now, after slowly decreasing to 0.3 a year ago (total hysterectomy + Ovaries 6 years ago) I feel and look great. I work out and hike, lift weights, would like to be 10 pounds thinner (5'9" and 155 lbs) but skin is gorgeous and hair thinning slightly but OK - cut it into a nice, young style.	I am thinking of going off completely 0.3 mg daily dose but fear headaches returning and I am a writer - can't afford to miss work like I did before starting Premarin. I can take hot flashes, but not Menopause Migraines! My only sister is a year younger and has Stage 4 breast cancer...a survivor for 8 years but not athletic and not a positive thinker. I don't like paying $45 per month for Premarin but bone density scan 2 years ago and heart test last year show I am in excellent health - bones of 35 year old. Lift weights, ladies! Vaginal dryness but Astrolube solves easily. Don't want to quit Premarin if daily quality of life would decline.	F	56	11 years		9/16/2008
5	hrt (hypogonadism)	only good side effects including weight loss ! (BMI was over 30)	My symptoms before trying it were : night sweats, muscle pain, osteopenia, high calcemia, high T4/TSH, libido decreased. I'm intersex (delayed puberty due to low LH-hCG bioactivity, partial gonadal dysgenesis)		41	12 weeks		4/18/2008 Email
5	complete hysterectomy at age 40	None at all! I stopped for awhile when all the scare studies about estrogen came out then asked to go back on them after a couple of years of horrible hot flashes and depression. I feel great with the low dose of this pill.	Take it, it works!	F	56	16 years		3/26/2008 Email
5	complete hysterectomy	No negative side effects	I have had none of the side effects others have mentioned. I feel the benefits far outweigh whatever negative press Premarin may get.	F	58	11 years		3/10/2008
5	Hot flashes	none	I feel great and look much younger than my years...	F	66	20 years		3/6/2008
5	Hot Flashes, Sleepless nights	I fell wonderful. I can finally sleep and hot flashes are gone. I have also lost 6 pounds in one month. I have been on premarin .3 for 6 weeks and am very pleased.		F	51	6 days		2/14/2008
5	Had surgery when I was 38 years old	Had no side affects until 8 months ago when my dr took me off it, then my hair started to fall out and my skin became so wrinkled! I have gone back on 1/2 dose, but plan to go back to full dose. I love my hair and the skin I had, want it back! I'm 69 and I'll continue taking 2.25 mg for the rest of my life.	I'll continue to take it. Started taking it when I was about 39 years old. It kept my skin beautiful and my hair didn't fall out until I stopped taking it.	F	69	30 years		1/29/2008 Email
5	total hysterectomy	I coulden't sleep after having my hysterectomy so doctor put me on .625 premeran apex three weeks after surgery. I go off of it on the 25 of the month and start again on the first.	I heard it was not good for you to be on premarin very long so apex 5 mo ago I started splitting mine in half. My hair is falling out my head is sore and have been having more cramps. I am 5.2 and weigh 135.I have not had any complications except my hair. I feel great, play golf and do yoga. I am going back to taking my.625 premeran.	F	77	25 days		1/20/2008
5	Hysterectomy	For the first few years, I gained weight, but I also ate a lot more. Occasionally, I have had problems urinating, but that goes away when I skip a day on the pill.	I am 65 and have been on the drug for 22 years. My doctor wants me off of it, and I did wean myself down to 3 pills at .6 mg a week. After six months, my skin is crepey and dry. I aged 10 years in those 6 months. Last week, I resumed daily use and feel much better already. I'll probably do five days on and two off at least until I am 70. I can find NO statistical data proving a link between estrogen-only usage and breast cancer. The data is all linked to estrogen-progesterin (which I refused to take 22 years ago after reading how unfavorably the Europeans were to it even back then). I think it's human nature to blame something when we get a disease. Premarin alone may or may not cause breast cancer, but the data just isn't there in my opinion. Quality of life means something here. My breast friend got a vicious form of breast cancer at 68 and she has a complete hysterectomy and NEVER HAD HORMONE THERAPY. So who knows?	F	65	22 years		10/24/2007 Email
5	hormone defiencincy	it is wonderful		F	51	15 years		7/30/2007
5	yes	Leg and feet pain with cramps. Swelling in the joints of the knees and ankles. Sever pain in the joints in my body especially legs. Anxiety, panic attacks. Blurred Vision. Caused Short Term Memory Loss. Heart problems such as palpatations. Weight Gain 50lbs. No matter how much I exercised and diet weight would not come off. Effected the urinary track.	I have had a complete hysterectomy 6 years ago. I went off premarin on June 10, 2007. I was taking 0.625 for 6 years. I am better now. I do not have the leg and feet cramps. I have lost weight. This medication made me retain fluid. I do not have heart palpations. All the side effects have left my body. I have been off premarin going on the 3rd week. with no hot flashes. I do not take any hormones.	F	45	6 years		6/26/2007 Email
5	Total Hysterectomy	None.	When I came out of the surgery at 39, my doctor immediately put a patch on. At my follow-up apptmt the next week he prescribed 1.25. Stayed on that for a few years, gradually reduced dosage to now taking one half of .45 daily. I have had no symptoms that I think can be directly attributed to this drug. The usual aches, pains and stiffness but I think that is normal for being 54 and not very active.	F	54	15 years		5/16/2007 Email
5	Complete Hysterectomy	None	I have no side effects from premarin. I see most complained about weight gain. Tried climara patch and retained fluid so decided to switch to premarin. The patch is what really put weight on me and since I switched to premarin lost 25 pounds. Back to being thin again but I also exercise, try to eat right, and drink alot of water. Only advice I can give you. Reading what others had said about estrogen levels I have not been tested yet since my surgery. I'm on .625 and take it every other day. I wonder if that's enough although I feel okay. Actually feel better now, more leveled out and calm compared to when I was still getting my menstrual cycle. As of right now I feel too good to consider going off even though I'm aware of the side effects you can get for long term use. Chance I'll take I guess.	F	38	1 days		1/21/2007 Email
5	total hysterectomy @ 24	None other than I look younger than my 50 years have greater energy and a better disposition.	I have taken 1.25 for 26 years and even though I still take it, I am now experiencing the sweats. No weight gain except the usual difference of youth & maturity. I don't sleep but I never did as a child. My eyesight has been bad for sometime and my prescription for them changes each year. My legs do not feel abnormally heavy, I've just gotten out of shape and lazier. I no longer go to drs because they won't listen to me when I tell them how I feel and simply want me to go off it. At last check my blood pressure was perfect and cholesterol was low on the bad side, high on the good. I would like to go off but don't see that happening anytime soon. Its about the quality of my life and every minute I want to enjoy it.	F	50	26 years		1/11/2007 Email
5	Hysterectomy and mood swings	None..but, my Doctor thinks it has caused a high gamma GT reading in my liver.On his advice I am taking a reduced level ie 0.625 evert third day.I want to stay on it forever, I feel and look great	Can it cause "liver sludge" ?	F	61	15 years		7/17/2006
5	Hysterectomy and mood swings	None..but, my Doctor thinks it has caused a high gamma GT reading in my liver.On his advice I am taking a reduced level ie 0.625 evert third day.I want to stay on it forever, I feel and look great	Can it cause "liver sludge" ? I came ff it when the panic about HRT started,the result was I felt terrible,I had awful night sweats,tiredness,moody and miserable.i am doing as the doctor suggested for 1 month to see if the liver count goes down. i feel OK o the reduced level so i will probably stick to that doseage.	F	61	15 years		7/17/2006
5	Hysterectomy and mood swings	None..but, my Doctor thinks it has caused a high gamma GT reading in my liver.On his advice I am taking a reduced level ie 0.625 evert third day.I want to stay on it forever, I feel and look great	Can it cause "liver sludge" ? I came ff it when the panic about HRT started,the result was I felt terrible,I had awful night sweats,tiredness,moody and miserable.I am doing as the doctor suggested for 1 month to see if the liver count goes down. At the moment I feel OK on the reduced level so I will probably stick to that doseage.	F	61	15 years		7/17/2006
5	Hysterectomy and mood swings	None..but, my Doctor thinks it has caused a high gamma GT reading in my liver.On his advice I am taking a reduced level ie 0.625 evert third day.I want to stay on it forever, I feel and look great	Can it cause "liver sludge" ? I came off it when the panic about HRT started,the result was I felt terrible,I had awful night sweats,tiredness,moody and miserable.I am doing as the doctor suggested for 1 month to see if the liver count goes down. At the moment I feel OK on the reduced level so I will probably stick to that doseage.	F	61	15 years		7/17/2006
5	mild hot flashes and much anxiety	I actually believe Premarin cured my headaches. I had migraines before and they quit after I started taking it. I'm now on the lowest dose. If I miss a few days, though, I get pretty clammy. Otherwise, I feel great.		F	58	7 years		6/5/2006
5	Total hysterectomy	The biggest at first was weight gain. But when I stopped and/or cut on the Premarin after years of taking it memory loss, headaches, mood swings, bed sweats, high blood pressure, and nervousness occurred.	1.25mg was the best dosage. 3 years ago, because of the controversy with Premarin I decided to stop taking it. The side effects kicked in. I had no idea what was wrong. After visiting my doctor, he put me back on Premarin and weeded me off instead. He cut me to .3 mg but it didn't help and switched me to .625 mg. I’ve been on it for 6 months. The bed sweats and headaches are back. I also developed mood swings, memory loss and nervousness. I’m not getting sleep at night and my energy level is low. I’m a 55 years old. I don't smoke, drink socially and has always been in great physical shape. I’ve gain 20 pounds over the past 5 years. I’ve always been a slender lady as it runs in my family. My doctor strongly advised I lose at least 10 pounds as he sees me approaching boarder line diabetes and the weight loss will prevent hitting the “concern zone.” I've scheduled an appointment with my doctor. Hopefully, he can get me back on track.	F	55	12 years		4/23/2006 Email
5	Hot Flashes - partial hysterectomy	Weight gain - may not be from Premarin. Quit smoking around the same time found out my thyroid wasn't working.	I had a partial hysterectomy in 1996 and started having the hot flashes roughly four years ago. Had been taking Estroven for that time but the hot flashes were disrupting my life. Started seeing an improvement within weeks. I believe this stuff saved my life. I was concerned about the Breast Cancer scare but my doctor says it's when you mix the estrogen and the other one together is when the risk comes in. Having yearly mammygrams will also decrease your risk of breast cancer deaths. Thank you Premarin - you saved my life.	F	47	8 months		3/23/2006
5	Total hysterectomy at age 28	I have never had any real side effects .... I believe it even helps me mentally ... I do have swollen ankles sometimes...but that could be due to many things... I did not like the weight gain ... I assume came from the premarin because it effects your thyroid ..	I have never had a problem related to premarin ... except the prempro...which effected my eyesight..lucky I figured it out quickly...and my eyesight returned to normal... which I was told would not happen...I feel no one should take the prempro.. .. I've taken regular premarin 1.25 since 1971 ... and feel it keeps me young ... many people compliment me on my youthful appearance ... could be genes ... but it is a fact you have more hormones when younger and better skin....	F	65	35 years		2/4/2006 Email
5	totaly hysterectomy	None	I did not mention in my orginal entry.....My surgeons recommended I take the premarin 3 weeks and leave off one week and I have always done this...which is more in tune with your body as before...I have had doctors argue with me...but I maintain the the time elements are important and the surgeons correct...I have done much research on hormones and their cycles... It is not normal to the body to have the same amount of estrogen all the time...progesterone cream is used the last week...just as the body would cycle these hormones...	F	65	35 years		2/4/2006 Email
5	Complete Hysterectomy	I wrote a post here about 6 months ago (read below)...well my sister has since passed away from Breast Cancer...which was feeding off estrogen. When I last wrote the post I was determined to stay on Premarin...but my doctor told me to get off it asap...because of my sister.	I HAVE BEEN OFF PREMARIN FOR 3 MONTHS...AND OTHER THAN THE OCCASSIONAL HOT FLASH - I FEEL MORE WONDERFUL THAN I EVER THOUGHT I WOULD. I CAN'T EVEN BELIEVE IT! EXCERCISE ALSO HELPS WITH THE HOT FLASHES IN THAT I DON'T GET THAT MANY. JUST TAKING CALCIUM FOR MY BONES...BUT I FEEL AWESOME...DON'T BE AFRAID IF YOU HAVE TO COME OFF OF IT...KEEP A POSITIVE MIND! KEEPING MIND OVER MATTER REALLY HELPS YOU TO OVERCOME MANY OBSTACLES!!	F	40	5 days		1/25/2006 Email
5	Total hysterecomy at age 35	None that I can discern, except those arising from the removal of ovaries and uterus, such as vaginal dryness, etc.	Primarily due to my proactive concern about future risk of Alzheimer's Disease, I intend to take Premarin forever. I feel great, look 20 years younger than chronological age, & have never had a hot flash since Premarin was literally administered on the operating table & I've never been without it since 1981!	F	60	25 years		1/11/2006
5	Hysterectomy ovaries removed@age23	Premarin has been a life saver for me. Has helped with night sweats, mood swings.	Although over the years I have been weening myself to a lower dosage. I haven't had any problems with taking it. I am currently taking .625 every two days.	F	48	24 years		1/8/2006 Email
5	HOT FLASHES, NIGHT SWEATS	Since 1987 gained 60 pounds, hard to lose, No more sweating, occasional slightly blurred vision, hair loss (had too much to begin with anyway)	stopping suddenly caused rage and sweating all night. Just not worth it. Stopping gradually caused vaginal dryness and the hot flashes started up again.	F	61	22 years		11/17/2005
5	Hot flashes at 42,total hysto at 47	My eye sight deteriorated, but that is always to be expected after age 40. Last few years heart rate went up and blood presure and cholesterol, but I believe that is a side effect of the Effexor I am on.	I felt SO much better once I was placed on Premarin. I welcomed some weight gain, but once I was at desired weight, I am able to control my weight with Calory counting (same as weight watchers point system). 2 Years ago I started to get break through hot flashes, not really bad, but mentioned it to the Doc. He gave me 3 different types of HRT to try, and adviced me to look for homeopathic herbs in addition (black Cohosh, Soy, estrovan, etc... ALL) The 3 different types of other HRT did not help. I weaned off all HRT and stuck it out with herbs for ONE WHOLE YEAR. I ended up almost insane (Head in freezer)and in addition I was hopitalized with a Phsychogenic stroke (4 months with no HRT), convulsions, mental hospital stay ( at 9 months after I stopped with HRT's). On disability and all ($710 a month). NO quality of life. My MD would not prescibe premarin again for me (he thinks I am nuts by now) I asked my Psych Doc. to be placed back on Premarin 1.25mg/day April this year, which he d	F	52	10 years		11/16/2005 Email
5	Hotflashes 42/total hysto 47	I have noticed the blurred vision, also more in one eye then another. Sugar has gone up, and now also Hormones from the adrenal gland dont seem to work properly ( Urge to Urine, frequent unrination, Large amounts of urine and discomfort with urination.(tested twice negative for UTI). I urinate 30% more then that I drink. Hands and ankles a little swollen of and on since about the last 6 months. BUT........(This can NOT be related to the Premarin)	I am looking into disorders of the Pituitary gland, which controls most of ALL hormones in the body. Disorders from the pituitary gland seem to have the same signs and symptoms as the side effects of the Premarin. I think I will check with an endocrinoogist.	F	52	10 years		11/16/2005 Email
5	Hysterectomy, Ovaries left in	Hot flashes, moodiness, water retention.	I have been on premarin for the last ten years and recently, like a lot of you went off because of reports of leg cramps, etc. I experienced such horrible sweats that I could not stand it. I feel young and very good when on the drug and was forced to return to it. I feel that I will probably take the drug as long as I live.	F	58	10 years		8/7/2005 Email
5	TotalHysterectomy w/ovaries removed	Premarin has been a life saver for me. I am on .625mg and have had no real side effects to complain about. The benefits outweigh the risks for me. Doctors like to perscibe this drug, especially for younger woman who have had a hysterectomy because they feel it keeps them youthful...which I agree...but I also agree that doctors are	My sister has had breast cancer and is now terminal. Her doctor told her cancer is feeding off estrogen...which is strange because she has had a complete hysterectomy and does not take estrogen...so, that tells you right there that your body does make estrogen in other ways. THis scares me to death and I am so torn to take it or not...but I feel my quality of life would be severaly interupted if I stoped. I think the best route is the lowest dose/shortest time possible, and when deciding to stop...DO NOT go cold turkey!!!	F	39	5 years		5/20/2005 Email
5	radical hystorectomy	don't seem to have any. unless I miss a dose? and Then I have the night sweats and hot flashes also was recently off for one month and have had terrible breast pain have been back on for one month it is still hurting but has eased some	I really wish it didn't have so many concerns to be on this medication because I feel so much better when I am on it	F	44	6 years		3/8/2005 Email
5	hysterectomy with one ovary left		10yrs. after surgery started getting hot flashes/insomnia & went on .3MG for 6 years then got off. After 2yrs off, hot flashes/insomnia came back with a vengence, day & night! I am back on .3MG and don't care if I ever get off. The risk is worth it to me. My legs ached to no end when I went off it, headaches were unbearable, usually 28 days out of a month, many of those days were spent in bed.	F	51	6.5 years		1/30/2005
5	Hysterectomy with ovaries out	I have been taking premarin since 1986 when I had my surgery. I have felt wonderful and expected to take it the rest of my life. Now my doctor says I should go off. I have been off for three months and my hair is thinning. My hair was thick and full while on the premarin. I thought it was good for the skin and hair. I am so disscouraged I am thinking of going back on. Anyone with this problem?	Great drug! My quality of life was maintained at 32 and I never felt better!	F	56	19 days		1/22/2005 Email
5	Surgical Menopause both ovaries	None - Premarin has been a life saver. I don't care if it's from horses urine...most people EAT animal don't they...so I don't understand what the big deal is there.	Recent studies scare me a little bit...but wait and new studies will reveal something different. The benefits I get while on Premarin far outweigh the risks! I will stay on it as long as I can just for current quality of life if nothing else!	F	39	5 days		1/4/2005 Email
5	Hysterectomy with 1 ovary removal	Breast tenderness for a couple of months.	I started taking it because I was not feeling well. Fuzzy mind, emotional, hot flashes, losing my hair, depressed. Heart palpitations, anxiety. Premarin has helped me and I feel great. I am very concerned about Cancer, either breast or ovarian. But I am not ready to go off of it.	F	46	3 years		9/22/2004 Email
5	hysterectomy	update from first rating......I went through a mental meltdown....I back BACK on my Premarin....I would rather live a shorter time....and be me...thank you Premarin...chronic sweats too much for me and then the meltdown too much.		F	54	7 years		5/2/2004 Email
5	menopause	No side effects I could directly attribute to Premarin. I did gain weight but attribute that to eating too much.	Since stopping Premarin 6 months ago due to bad publicity, I have experienced hot flashes (mostly during night), severe insomnia and body aches mainly in legs during evening. Also experience severe stiffness after sitting for short periods. I eat properly, take calcium and glucosamine condroitin, exercise regularly and I am in otherwise excellent health. I have resumed Premarin but too soon to see if it helps terrible leg pains. Have others experienced leg pain after stopping Premarin (no progesterone dut to partial hysterectomy)?	F	65	16 days		4/16/2004 Email
5	hysterectomy	I took Premarin for 7 yrs..only side effect was weight gain...w/ so many news reports..I went off it a month ago...I SUFFER from hot flashes, night sweats,...I wish that I could find something to help the hot/cold sweat/chills and I would be real happy.....I miss my meds and am debating going back to them		F	54	7 years		4/13/2004 Email
5	Surgical menopause	None	I've been able to lower my dose over the years as I've aged.	F	44	15 years		2/23/2004
5	Total Hysterectomy	Just after returning home from my surgery and before beginning Premarin, I had a few hot flashes, but since starting the medication, I haven't had any hot flashes and feel like a teenager again! I have noticed some hair loss...a little more than before taking Premarin. I am on the lowest dosage, .65 mg/daily.	I think Premarin is a	F	39	3 months		9/30/2003
5	total hysterectomy w/ovaries	Some moodiness, tendency to be mopey, a few hot flashes that disappeared after the first few weeks.Palpitations disappeared,feel better, although I have lost my appetite	I believe this medication is very helpful for me, maybe not for all women.I will continue this med for as long as my Dr. will give it to me.After five years of much distress, the hysterectomy & Premarin have brought back who I used to be.	F	41	45 days		9/29/2003 Email
5	total hysterectomy	NONE	I went off premarin for 10 months after taking it for 5 years. Terrible, terrible hot flashes, lack of energy (I gained weight because of inability to exercise), stiffness, more headaches than usual (I don't get them). I've been back on premarin 2 weeks and have been feeling much more like myself. I won't go off again--any risks I'm willing to take for quality of life!	F	32	5 days		5/1/2003
5	total hysterectomy	some weight gain	how long should it be taken?	F	67	15 years		4/2/2003
5	Hot flashes	I won't blame Premarin for this weight gain because it just started piling on the last 2 years since periods stopped.	You don't realize how wonderful this pill is until you run out of it. The blurred vision, big stomach and serious hair loss didn't occur until sixteen years after I started the pills! Good thing I had real thick hair to begin with.	F	59	18 days		3/31/2003
5	hot flashes; temporary insanity	no more hot flashes or insanity. Murderous fantasies vanished. Turned into Cool Hand Luke immediately. : )	Don't blame Premarin cause you gain weight a decade or more after starting it; that's silly. I'd have gotten this disgusting, asexual beer belly, thinning hair and blurred vision regardless. I think its a Golden Years thing.	F	59	18 years		3/31/2003
5	Total hysterectomy w/ovaries	More energy, better skin, better sleep at night...I feel great	Went off Premarin for a month when preparing for breast biopsy to remove questionable tissue...once I found it was NOT cancer, went back on...last three weeks I was off were miserable... terrible hot flashes, sleepless nights, headaches and loss of appetite. I felt awful. W/i a week of going back on, felt great again. I have history of colon cancer and heart disease in my family--life's a gamble...premarin is a chance I'm glad to take.	F	45	8 years		1/9/2003 Email
5	Surgical Hysterectomy due to endo	Breast Tenderness	A real Lifesaver.. Recently weaned off for 9 weeks and suffered terribly. Hot Flashes, Sweats, Cold Chills, Moody, Crying Spells, etc.. The only benifit of stopping was no breast tenderness.	F	39	11 years		11/19/2002
5			OOOOOPS!!!!! I FORGOT TO CHANGE THE GENDER MARKER. I AM A FEMALE	F				11/15/2002 Email
5	TOTAL HYSTERECTOMY	AFTER THE FIRST 4 MONTH OF TAKING PREMARIN.I FINALLY DECIDED THE REASON I DIDN'T FEEL LIKE MYSELF WASN'T BECAUSE I WAS STILL HEALING IT WAS BECAUSE I NEEDED MORE PREMARIN THAN I WAS GETTING. I CALLED MY OB/GYN AND HE DID A BLLOD TEST THAT TESTS FOR LEVELS AND SURE ENOUGH MINE WAS TO LOW.I AM GOING TO HAVE HIM CHECK IT EVERY YEAR EVEN IF I HAVE TO SUGGEST IT.IN THE 10 MONTHS THAT HAVE FOLLOWED I HAVEN'T HAD ONE SIDE EFFECT.	ITS SO NICE NOT TO WORRY ABOUT FEMALE PROBLEMS!!!!!!!!!!!!!!!	M	32	21 months		11/15/2002 Email
5	osteoporosis	none			51	6 months		10/16/2002 Email
5	osteoporosis	none		F	51	6 months		10/16/2002 Email
5	total hysterectomy @ 26 due to endo	I think of side effects as a negative thing and have nothing negative to say about Premarin. It is my (and my family's) life saver!	I am taking 2.5 mg of Premarin daily and have been for the last 12 years. I have tried to decrease it to 1.25 several times because of the concern of possible side effects. However, I have always began to experience hot flashes and terrible mood-swings so I would go back to the higher dose!	F	38	12 years		9/17/2002 Email
5	surgical menopause	Hot flushes, ovary pain		F	60	30 years		9/8/2002
5	Complete Hysterectomy	None	At my doctor's suggestion, I quit taking it recently; however, the hot flashes returned as did erratic emotions -- therefore, I quickly was placed back on it.	F	56	22 years		7/22/2002
5	partial hysterectomy at age 35	water weight gain at first. it gradually went away. felt more calm, energetic and alert.	i've been taking premarin for 15 years. i am 5 ft 8 in tall and still am at age 60. it has aided in retaining my yourthfullness. i never had a problem with it...ever. the controversy today on the news is causing me to consider weaning off but i really don't want to.	F	60	15 years		7/13/2002 Email
5	Complete hysterectomy incl. ovaries	Nothing bad, only good. No more hot flushes or bad moods	Initial concern following recent results of study group in USA, but my Doctor has advised me to stay on it at this stage due to the recorded decrease in bowel cancer of which I have a family history	F	57	6 years		7/13/2002 Email
5				F	25	7 days		2/7/2002
5	Drs orders	None		F	78	30 years		11/24/2001
4	Menopause	memory loss,joint pains	stopped taking Premarin for 3 months,symptoms all returned.i.e.flushes,nervousness,i was really irratable and felt dreadful.Started taking it again,felt great.Now my GP has instructed me to stop taking Premarin,states the longer i am on it the higher the risk of Cancer.States just stop now,go cold turkey.the thought of just stopping fills me with dread.Any comments please.	F	58	5 years 1.25 1X D		4/14/2010 Email
4	Hot flashes	None	I started menopause at age 40. I have tried soy supplements with no help for my hot flashes (every 45 minutes) I am trying to go off due to cancer concerns but the quality of life isn't worth it. Has anyone tried Amberen?	F	59	15 years		1/21/2010 Email
4	total hysterectomy aged 32	i was given a total hysterectomy at 32 after years of suffering severe pain due to endriometrious .i would total recommend this type of hrt apart from a little weight gain which could be age or diet related anyway , my hair skin and health are better than they have been throughout the earlier part of my life .	i feel this is a very good hrt and ive been very happy with it .	F	44	11 years		4/2/2009
4	Total Hysterectomy	weight gain-15 lbs., tingling, joint pain, stiffness and exhaustion	I can't afford night sweats due to diabetes-and know Premarin helps me look younger, I have tried going without before and didn't like results. I take insulin and synthroid so am confused as to whats causing what. Have been on .625 Premarin-after reading posts I will try and decrease the Premarin to see if any improvements. Sugars and thyroid tsh are great.	F	55	17 years		3/20/2009 Email
4	Total Hysterectomy - Age 38	Slight Memory loss (but always been a bit scatty!), mood swings, a little weight around my belly	I can honestly say since having my hysterectomy and taking Premarin (1.25mg now - the lower dose originally made me feel very tired) I have felt so much better. Having suffered since my early 20's with endometriosis and adenomeyosis I feel rejuvenated. My skin is glowing and I look and feel great. Lucky to conceive twins at the age of 37 with the help of IVF, I have a pain free life and the slight side effects are a small price to pay and do not worry me. I feel pain free for the first time in 15 years and enjoying my fantastic life.	F	40	2 years		2/17/2009 Email
4	Total hysterectomy at age 25	none	I had to have a full hysterectomy at age 25. I dealt with some depression as a result of it. I dont feel that the pill caused the depression, I think it was just me getting usto the idea that I will never have the possibility of having a child of my own DNA. I thought it may have ben the drug causing my depression so i quit taking it. I received sever hot flashes and mood swings. Once i started taking the pill again, I leved out. I would like to warn younger people who have had their ovaries removed thinking of quitting hormone replacement. Please consult your Dr. before stopping, your risk of developing osteoporosis is greatly increased. The benifits greatly outway the risks for me having to take hormone replacemnt at such a young age. I am no Dr. but thats what my Dr. told me.	F	28	3 years		2/13/2009 Email
4	Totaly hysterectomy on 1/29/08	Total hysterectomy due to endometriosis, bleeding in fallopian tubes and cysts on my ovaries. After that I experienced dry skin, aches in shoulder & knee joints, and hot flashes. My body suddenly felt very old. Sexual feelings/urges were completely gone. I felt like I'd been castrated, it was so apparent that a part of me was missing. After 2 week follow-up appt, the MD placed me on 0.625mg of premarin. However, the physical problems persisted. In my 3 month follow-up visit, I asked for an increase in dosage and the MD changed it to 1.25mg. The problems went away in 2 days and I felt normal again. But in the following 3 months after my 2nd appt, I gained over 30 lbs!!!	I have concerns about the abuse of mares in the maufacturing of Premarin. I'm also greatly concerned about it's risks for causing heart disease, breast cancer, etc. But even though I'm fat, I feel more normal and able-bodied with the Premarin, than without it. Still, I'm thinking about asking the MD to lower the dosage one notch just to cut health risks and see how my body adjusts. And I'm trying to take off the weight.	F	48	1 years		2/6/2009 Email
4	Full Hysterectomy	None I can directly blame on this drug. Did have weight gain but this was most likely due to inactivity after operation. My libido is fantastic and I'm looking good for my age.	Enforced Hysterectomy at 39. Been taking 1.25mg for 10 years. MY SANITY SAVER. My doctor wants to take me off it due to high blood pressure and the length of time taking premarin I am fighting to stay on premarin.	F	49	10 years		1/20/2009
4	lichen sclerosis	weight gain (?), breast tenderness	premarin HAS helped my lichen sclerosis although i don't like the idea of being on it long-term.	F	34	10 months		12/31/2008
4	Hysterectomy/Oophermectomy	WEIGHT GAIN, sore breasts	When surgical menopause hit me in the face, it was ugly. Hot flashes, night sweats, insomnia, weepiness, depression, low low body temp, constantly shiivering, just wanting to crawl out of my skin. I tried over the counter herbal remedies, nope- did not help. So I had to try Premarin or stand in front of a train, that's how awful I felt. I started on .625 of it, and felt a huge relief in a matter of days. I did notice that after a week or so, my stomach was a big bloat- like a full tick! Then my breasts were quite full (I'm basically a flatsy) they also hurt, kind of like I was going to get my period, my whole demeanor was that of PMS queen, but I knew I wasn't going to get my period, so I started to take one pill every other day, and some symptoms were alleviated. I now take .32 every other day, my hot flashes are somewhat more frequent, but the other symptoms aren't back, so that's good, I do hope this will allow me to lose the 18lbs I have gained, I eat low carb, and exercise a	F	42	6 months		10/8/2008 Email
4	hysterectomy	hot flushes	I was on Premarin for 15 years, I decided to come off of it, I did it gradually, for 3 months I took one every other day, and then for another 3 months I took one every 3 days, and gradually to 1 a week until I finally stopped and it worked no more symptoms, before on premarin, I was aggressive, depressed, my stomach was bloated, I put on weight, my hair was getting thin, my legs were stiff and I was breathless, I am 65 and feel much better now that I am off of it. If you want to stop taking it, you have to do it gradually or your symptoms return with a vengeance.	F	65	15 years		9/2/2008
4	Post-Op Transgendered Woman	I dont produce estrogen or testosterone. So, I only need a very low dosage..a .3 mg every other day. I have taken estradiol for 4 years, and premarin for 6 years now, and I have found that premarin is better for two reasons. Premarin is a lot more potent than estradiol, especially the "half-life", or how long it stays in your body. If my dosage isnt just right, I would have all the side effects that everyone has mentioned! I have had all those symptoms, and simply just started to do all the research, get my blood levels checked, and ween down to a lifetime, best maintenance dosage. I rated it a 4, because of two reasons. One, its more conveinent to take than estraidol is. You would have to take estradiol twice a day, because the "half-life" is only around 3 hours for estradiol, compared to around 15-20 hours for premarin. You just have to make sure to take the lowest dosage that you actually need. Premarin is potent..much more ptotent than estradiol! You will only h	I have done lots and lots of research about hormones, vitamins..etc. I am a Post-Op transgendered woman..since oct. '03. I dont produce estrogen, or testosterone anymore, and my lingering amount of testosterone is constantly at around 17 ng/dl, which is very, very low for a female. So, I only need a tiny amount of premarin(estrogen) now, and its just for bone density/maintenance dosage(.3 mg every other day). There is some research that people arent doing here, and I want to explain this. First, estrogen therapy increases copper levels in the body. Estrogen, and copper levels parallel with eachother. Zinc, which is an atagonist of copper, and the opposite of copper, should be increased if on estrogen therapy!! If you are having blurry vision, joint pains, libido problems, acne breakouts, thinning hair, colds/flu..etc, its most likely because you are high on the copper side, and low on the zinc side. You should be at a level of around 12 mg of zinc, to 1 mg of copper ratio for optimum h	F	40	10 years		8/9/2008 Email
4	Total Hysterectomy	Some depression	It has been great for me my doctor had to adjust my dosing after that i have been good.	F	30	4 months		7/30/2008 Email
4	TAB due to borderline Ovarion Tumor	Sides Effects FROM the Premarin? I have gained 20 pounds and find it hard to get off even through diet and exercise. My Cholesterol and BP are up - but this could be the weight gain.	I was miserable about a month after surgery and the GYN/ONC prescribed Premarin and it was great. Going through surgical menopause while recovering from a major surgery was just not an option. I have been tapering off of the Premarin for 6 months now.Sometimes when I would lower the dosage I had minor symptoms My last dosage before quitting was .145 every other day. I have been completely off for two weeks. I have had night sweats, hot flashes and have mostly felt achy and tired. I am determined to be through with this medication- so hopefully things will settle down soon.	F	46	18 months		7/13/2008
4	Perimenopause and PMDD	Tired and fatigued.	Since taking Premarin, I am finding LESS hair in the shower drain. Emotionally, I feel more like my old self. The weepiness is gone and my PMDD symptoms are less.	F	44	3 weeks		7/6/2008
4	TAH & Oopherectomy 2001 @ 35yrs	Hot flushes, tearfulness, forgetfulness, anger, impatience, insomnia, depression.	I have had no menopausal symptoms since taking premarin but I have gained about 7lbs around my middle which won't shift, and I am beginning to get downy facial hair. My main problem is that I have been getting dreadful hemiplegic migraines since taking Premarin. I get one or two a month which is relatively few compared to some mirgaine sufferers but they are severe and I cannot function for about 24 hours afterwards. I dread travelling to other sites with work in case I get a migraine while driving. My Doctor wants me to stop HRT but I am reluctant to go back to the insomnia and depression. I honestly feel that I cannot function without HRT I have been trying Pizotifen & Propranolol along with Sumatriptan but I am still getting the migraines. Going to see Doc tomorrow about changing to an HRT patch. If that doesn't work I will stop taking HRT and see what happens.	F	40	5 years		6/29/2008
4	Both Ovaries Removed	Slight weight gain	My only complaint is slight weight gain. I have to be much more careful on what I eat than ever before. My terrible night sweats and hot flashes throughout the day are almost obsolete. My mood has been terrific. I had severe vaginal dryness but since taking the oral Premarin as well as the vaginal creme - intercourse is enjoyable again without the pain.	F	30	30 days		6/14/2008

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Average rating for drug: 3.2. This page is printer-friendly; use landscape print with background color turned on.

Key to ratings: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine.

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