PREMARIN Reviews (ESTROGENS, CONJUGATED)

Average Rating: 3.4 (505 Ratings)

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PREMARIN  (ESTROGENS, CONJUGATED):  This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PREMARIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PREMARINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  TOTAL HYSTERECTOMY AFTER THE FIRST 4 MONTH OF TAKING PREMARIN.I FINALLY DECIDED THE REASON I DIDN'T FEEL LIKE MYSELF WASN'T BECAUSE I WAS STILL HEALING IT WAS BECAUSE I NEEDED MORE PREMARIN THAN I WAS GETTING. I CALLED MY OB/GYN AND HE DID A BLLOD TEST THAT TESTS FOR LEVELS AND SURE ENOUGH MINE WAS TO LOW.I AM GOING TO HAVE HIM CHECK IT EVERY YEAR EVEN IF I HAVE TO SUGGEST IT.IN THE 10 MONTHS THAT HAVE FOLLOWED I HAVEN'T HAD ONE SIDE EFFECT. ITS SO NICE NOT TO WORRY ABOUT FEMALE PROBLEMS!!!!!!!!!!!!!!! M 32 21 months
11/15/2002
 4  complete hysterectomy w/ovaries rem struggle keeping weight off, "budda" belly, irritability, tiredness, hair loss, vision sometimes blurred The good part is I don't have hot flashes and have good health and every other way. Walk 3-4 miles 5 times a week and maintain a active lifestyle. M 57 6 years
7/20/2002
 4  Breast enlargement m/f Hightened emotions, depression, nipple tenderness, heart palipitations, slight breast enlargement, weight gain, slight vision problems, constant changes in labito. Have taken varried doses from .3 to 5.0 per day over the last 2 years. Have taken a few breaks where I stop taking it for a week or so, seems to help with heart problems. M 50 2 years
3/29/2004
 3  hysterectomy bloating weight gain acne took away hot flashes M 52 10 years
2/4/2009
 3  Menopause So far no side effects!! I started Premarin just a few days ago. I still have hot flashes, and night sweats, just not as intense. I am hoping after a few weeks my anxiety, hair thinning, and lack of libido will return. I heard of women having excellent results with Premarin so fingers crossed!! M 52 4 days
.625 1X day
2/9/2015
 1  Hysterectomy and to protect my bone Thin bone, enlarged my heart, irregular heart rate, joint, muscle pain, serve headaches, sore on my arm that would not heal, anxiety, memory problems, personality changes, panic attack, depression, pre cancer cell had to have laser treatment, masses weight gain, serve breast pain, had a knee replacement. I have an allergy to horses. I also have been told I have Fibromyalgia and I think this drug is the cause. Started taking this pill when I was 40, it was nothing but hell for me. I was told when I was in junior high school that I reacted to horses and that I should never eat horse meat, or anything that came from horses. When I started taking this drug I did not know it came from horse, I was a farm wife raising 4 kids. When I found out the doctors would not listen to me about the side effect I was having, I was on the drug about 5 years when I found out. I was on the drug for about 12 years. This drug destroyed my life. I walked on a broken foot for almost 3 years because the doctors keep saying I was protect because I was on premarin. I was refused care because of this drug. I fear I will not get medical care in the future because of this drug. The very first pill made me sick, told my Doctor and he called me a lair. M 57 12 years
10/23/2007
 1  Total Hysterectomy I became so nervous I constantly felt like wanting to jump right out of my skin, and on top of that I also became so angry I could have eaten people up! That's the total opposite of the kind of person that I usually am. Had to quit. Coped with hot flushes for a few years, and more recently with bone loss but, hey, it's life! I now take calcium every day, but I never feel that horrible tension and anger I felt while on this medication, so I never regretted quitting it. M 61 2 weeks
7/16/2008
 1  total hysterectomy Since my hysterectomy in 1995, I have been on Premarin 1.25mg every day. Since then I have gained about 25 pounds. A bloated feeling has stayed with me the last 2 to 3 years. Even facial puffiness. The hair loss was scary. My eyes seemed to be getting really blurred and it was hard to focus on things. Awareness of my heart beating all the time bothered me. I would wake up and my heart would be racing and pounding at the same time every day. I have grasped for a diagnosis of something in the past 2 years, not knowing what caused it. I had to reorder my prescriptions in the mail. Noticing I would run out of the Premarin, I just did not take one for a couple of days. Then, after taking one the third day, I felt breathless, heart pounding, lethargic, till I finally gave up and laid down the rest of the day. I thought back to that morning and the Premarin was the only thing different I had taken that day. Thank God I did. I feel so much better physically and mentally. The bloated stomach has now subsided. My face has lost the puffiness. I cannot believe the difference. I will not resume taking the Premarin, no matter what! I will live with the hot flashes, etc. rather than take this drug. M 50 7 years
3/20/2003
Email
 1  Hysterectomy, then Ovaries removed Dibialiting Headaches, rapid aging, depression, anxitey, weight loss Had total hysterectomy due to endo, then ovaries removed 6 months later due to severe scar tissue. Doctor put me on 0.625 and felt great at 1st but gradually started getting dibialiting headaches, then depression, anxiety and weight loss. I also felt like I aged about 5 years in 9 months. Went to female gyno who also had ovaries removed and told me to throw Premarin in the trash. She told me about Estrogel which is the HRT that she is on. I tried it and within 2 weeks felt like my old self again. Headaches are gone and my skin and hair look great!!! I do have a little anxiety but nothing that interferes with daily activites. I run 4 miles 2 times per week, bike 15 miles 3 times a week and swim twice per week. I am 47 and feel so great that I've actually signed up to do my 1st Triathlon. That would have NEVER happened if I was still on Premarin. Plese throw your Premarin away and ask your Dr. to prescribe Estrogel 0.06%. M 47 9 months
0.625 2X day
6/8/2010
 1  surgical menopause Felt tired, had foggy brain, low energy, no sex drive, migraines daily 14-16 hours after taking each dose. Switched to an estrogen patch, and am back to being myself! M 33 2 weeks
1/5/2006
 5  Complete Hysterectomy I wrote a post here about 6 months ago (read below)...well my sister has since passed away from Breast Cancer...which was feeding off estrogen. When I last wrote the post I was determined to stay on Premarin...but my doctor told me to get off it asap...because of my sister. I HAVE BEEN OFF PREMARIN FOR 3 MONTHS...AND OTHER THAN THE OCCASSIONAL HOT FLASH - I FEEL MORE WONDERFUL THAN I EVER THOUGHT I WOULD. I CAN'T EVEN BELIEVE IT! EXCERCISE ALSO HELPS WITH THE HOT FLASHES IN THAT I DON'T GET THAT MANY. JUST TAKING CALCIUM FOR MY BONES...BUT I FEEL AWESOME...DON'T BE AFRAID IF YOU HAVE TO COME OFF OF IT...KEEP A POSITIVE MIND! KEEPING MIND OVER MATTER REALLY HELPS YOU TO OVERCOME MANY OBSTACLES!! F 40 5 days
1/25/2006
 5   Water retention.but feeling great can't live without it . F 50 3 years
2/26/2013
 5  Hot flashes at 42,total hysto at 47 My eye sight deteriorated, but that is always to be expected after age 40. Last few years heart rate went up and blood presure and cholesterol, but I believe that is a side effect of the Effexor I am on. I felt SO much better once I was placed on Premarin. I welcomed some weight gain, but once I was at desired weight, I am able to control my weight with Calory counting (same as weight watchers point system). 2 Years ago I started to get break through hot flashes, not really bad, but mentioned it to the Doc. He gave me 3 different types of HRT to try, and adviced me to look for homeopathic herbs in addition (black Cohosh, Soy, estrovan, etc... ALL) The 3 different types of other HRT did not help. I weaned off all HRT and stuck it out with herbs for ONE WHOLE YEAR. I ended up almost insane (Head in freezer)and in addition I was hopitalized with a Phsychogenic stroke (4 months with no HRT), convulsions, mental hospital stay ( at 9 months after I stopped with HRT's). On disability and all ($710 a month). NO quality of life. My MD would not prescibe premarin again for me (he thinks I am nuts by now) I asked my Psych Doc. to be placed back on Premarin 1.25mg/day April this year, which he d F 52 10 years
11/16/2005
Email
 5  Hotflashes 42/total hysto 47 I have noticed the blurred vision, also more in one eye then another. Sugar has gone up, and now also Hormones from the adrenal gland dont seem to work properly ( Urge to Urine, frequent unrination, Large amounts of urine and discomfort with urination.(tested twice negative for UTI). I urinate 30% more then that I drink. Hands and ankles a little swollen of and on since about the last 6 months. BUT........(This can NOT be related to the Premarin) I am looking into disorders of the Pituitary gland, which controls most of ALL hormones in the body. Disorders from the pituitary gland seem to have the same signs and symptoms as the side effects of the Premarin. I think I will check with an endocrinoogist. F 52 10 years
11/16/2005
Email
 5  Total hysterectomy at age 28 I have never had any real side effects .... I believe it even helps me mentally ... I do have swollen ankles sometimes...but that could be due to many things... I did not like the weight gain ... I assume came from the premarin because it effects your thyroid .. I have never had a problem related to premarin ... except the prempro...which effected my eyesight..lucky I figured it out quickly...and my eyesight returned to normal... which I was told would not happen...I feel no one should take the prempro.. .. I've taken regular premarin 1.25 since 1971 ... and feel it keeps me young ... many people compliment me on my youthful appearance ... could be genes ... but it is a fact you have more hormones when younger and better skin.... F 65 35 years
2/4/2006
Email
 5  totaly hysterectomy None I did not mention in my orginal entry.....My surgeons recommended I take the premarin 3 weeks and leave off one week and I have always done this...which is more in tune with your body as before...I have had doctors argue with me...but I maintain the the time elements are important and the surgeons correct...I have done much research on hormones and their cycles... It is not normal to the body to have the same amount of estrogen all the time...progesterone cream is used the last week...just as the body would cycle these hormones... F 65 35 years
2/4/2006
Email
 5  Hot Flashes - partial hysterectomy Weight gain - may not be from Premarin. Quit smoking around the same time found out my thyroid wasn't working. I had a partial hysterectomy in 1996 and started having the hot flashes roughly four years ago. Had been taking Estroven for that time but the hot flashes were disrupting my life. Started seeing an improvement within weeks. I believe this stuff saved my life. I was concerned about the Breast Cancer scare but my doctor says it's when you mix the estrogen and the other one together is when the risk comes in. Having yearly mammygrams will also decrease your risk of breast cancer deaths. Thank you Premarin - you saved my life. F 47 8 months
3/23/2006
 5  HOT FLASHES, NIGHT SWEATS Since 1987 gained 60 pounds, hard to lose, No more sweating, occasional slightly blurred vision, hair loss (had too much to begin with anyway) stopping suddenly caused rage and sweating all night. Just not worth it. Stopping gradually caused vaginal dryness and the hot flashes started up again. F 61 22 years
11/17/2005
 5  Hysterectomy ovaries removed@age23 Premarin has been a life saver for me. Has helped with night sweats, mood swings. Although over the years I have been weening myself to a lower dosage. I haven't had any problems with taking it. I am currently taking .625 every two days. F 48 24 years
1/8/2006
Email
 5  Total hysterecomy at age 35 None that I can discern, except those arising from the removal of ovaries and uterus, such as vaginal dryness, etc. Primarily due to my proactive concern about future risk of Alzheimer's Disease, I intend to take Premarin forever. I feel great, look 20 years younger than chronological age, & have never had a hot flash since Premarin was literally administered on the operating table & I've never been without it since 1981! F 60 25 years
1/11/2006
  

PREMARIN  (ESTROGENS, CONJUGATED):  This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).    (Sources: U.S. Centers for Medicare Services, FDA)

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