PREMARIN Reviews (ESTROGENS, CONJUGATED)

Average Rating: 3.4 (505 Ratings)

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PREMARIN  (ESTROGENS, CONJUGATED):  This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PREMARIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PREMARINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Complete Hysterectomy Stop the change I was 28 yrs old. It eliminated depression,stop not flash I maintain sex drive. I stope smoking no Hard drink and no cokes reducd caffeine, reduce sweets sugar intake, excerise regularly. I took vitamin C,COQ10, omega fish,soy in a lecithin, very small a amount beef I constantly read on what can do to. Cleanse my liver. My breast has cyst NO cancer, and cyst in liver. I found each time my Doctor want me reduce to cream or stop premarin my blood presure goes up, energy goes down, my short term memory is bad real bad and I depression starts I feel weakest . I am not over weight. I do not want to reduce my quality of life and most of all I Do not want to loose my memory. When stopped my premarin 5 days I forgot my neighbor first names who I known for years. Then I started my premarin dosage .925 mg in few dàys my short term memory came back,thank God. I also started taking cream for women of testosterone a little . I have concerns so I read research and studies trying to put off toxicity. I know I can not stop premarin because it gives me the best quality of life memory,energy mo depression. My friend quit premarin she ended up diabetic cause she was. Over weight F 71 58 years
.925 1X day
6/26/2013
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 5  complete hysterectomy- 30 yrs old None. Now, after the reports of cancer and stopping taking it, I'm having hot flashes. How long do they last??? Never had any side affects, just didn't have to suffer the hot flashes. If there isn't any hope of getting rid of them, I'd go back to taking it again. F 77 47 years
.625 1X day
3/6/2011
 5  Total hysterectomy aged 26yrs Nil side effects. Now aged 72 yrs gained weight. 1.25mg for 45yrs now .625mg occasionally flush at aged 72yrs. I look years younger and have no wrinkles and smooth skin... Premarin is a wonderful estrogen drug..Gynecologist says stay on it because of the long period of 46yrs..when I reduced dosage had slight side effects example flushes. 72 46 years
.625 1X day
9/8/2020
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 5  TOTAL HYSTERECTOMY NO NEGATIVE SIDE EFFECTS DEXISCAN PERFEECT/SLEEP WELL/.FEEL HEALTHY/ NEW GYN ASKED ME TO SWITCH TO ELESTRIN LAST WEEK/ CANNOT SLEEP/ NIGHT SWEATS/HAVE GREAT SKIN/ALERT AND VERY HAPPY WITH PREMARIN /NOW I HAVE TO PERSUADE GYN TO WRITE Rx FOR PREMARIN. F 85 41 years
0.625 1X day
9/7/2011
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 5  hot flashes No side effects. Weight gain is normal for sedentary women. I've gained 60 lb since starting. I can't live a life with little sleep. Worried since mother died of massive stroke at 83 and she took this for decades too. F 69 40 years
.625 1X day
4/21/2013
 5  Pan Hysterectomy This has been a "wonder drug" for me. Had to have uterus, ovaries, fallopian tubes and cerviix removed because of tumour in 1966 at the age of 24!. Started out with hormone implants in the stomach every 3 months, but then went to PREMARIN!! Was told I would need to be taking them for life. Now current Dr trying to take me off, saying not necessary! Have tried but become irrational with emotions all over the place.and feel awful - Premarin keeps many symptoms of aging at bay for me. At 72 still haven't gone gray and skin relatively wrinkle free but best of all absolutely NO bad side effects! F 72 40 years
.625 mg 1X day
11/5/2014
 4  Had a hysterectomy at 34 None Started it after my hysterectomy. I am healthy with no physical or emotional problems over the years. I take no other RX drugs. F 74 40 years
.625 1X day
4/21/2015
 5  Hysterectomy at 19 None, ever. I had a medically necessary hysterectomy at age 19. I have been on Premarin 0.625 since I was 19 years old. My surgeon told me he was putting me on 0.625 so that I could take Premarin the rest of my life. It has worked for me with no adverse effects. I have osteoporosis that I would not know but for bone scan. Otherwise in perfect health. My new doctor wants me to stop taking it, says a 57 year old woman has no business taking Premarin. I know if I stop I will spiral into bad health. You'd think I was asking to continue on a truly dangerous drug like opioids or something (again I take no other meds). We know our bodies better than anyone, doctors should really listen to their patients - health is not a one size fits all. F 57 38 years
0.625 1X day
5/23/2023
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 5  Total hysterectomy at age 25 same as with regular menstrual cycle - increased water retention during course of the month and some tenderness in breasts with a decrease of side effects during last 5 days of month when not taking the medication At age 50 my doctor advised that I stop taking Premarin because of the possibility of susceptibility to heart attack, cancer and stroke. As a direct result began having hot flashes, night sweats, dry skin, reduced mental acuity, was unable to sleep, had loss of libido, acute joint pain and depression. I suffered miserably with these problems for 8 months and they did not diminish. After taking into consideration my reduced quality of life, I decided that it was worth the risk to begin taking Premarin again to see if the probems would disappear. I began taking a dosage of 1.25mg every other day and was relieved to find that my symptoms began to disappear within a week or so. I am currently taking .625mg/day and have some joint aches and pains, drier than normal skin, occasional mood swings, weight gain and fluid retention. Overall I think the possible risk of stroke, cancer and heart attack does not outweigh the poor dally quality of life that I experienced while not taking Premarin. Possibly I may live a few years less, but my quality of daily life is far superior when taking the drug; therefore I will continue to take Premarin. After having read some of the comments here, I considering taking a higher dose to see if the joint aches and pains occasional night sweats, loss of libido and dry skin and mood swings disappear altogether. F 63 38 years
.625 1X day
10/31/2011
 5  complete hysterectomy none Over the last 10 years I have reduced my dosage from 1.25mg to .625mg daily. My Doctor wants me off completely because heart disease is prevalent in my family. We continue to debate this. I continue to take .625 mg. At age 48 my previous physician told me his 94 year old Mother was still taking Premarin and I should too. 59 37 years
1.25 1X day
6/2/2011
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 5  complete hysterectomy none I beleive as soon as I got on them they began to work their magic and continued throughout the years. Lucky Me. Back in the day I remember when I was younger the older ladies use to call them the banana pills. Do not ask me why, maybe because mine are oblong and yellow, yet not all premarin are looking the same. Yes I have additional comments. I was suggested by physicians a few times to get off of premarin and I tried until I experienced physical pain that I didn't like and at the time I was on percocets and that didn't kill the pain. So as I continued to suffer I said enough is enough. As i went back on my Premarin the pain went away just like that, therefore I told the Dr at the time. Then once again to the next Dr and then again to the next Dr then after this many times I said enough is enough because everytime it was the same, Pain. A new Pain. Comming from not being on Premarin so Drs said my body is addicted or my body needs it and I say I don't care just give me my script I need my Drug!!!!!!!!!!!! F 67 37 years
1.25mg 1X day
1/14/2018
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 5  Hysterectomy at 42 years old None - I can't blame putting on 4 pounds to Premarin - I like cheesecake!! A few years back, there was a big issue about my wonderful Premarin. I decided to come off it. Talk about the blahs!!!! I went back on after 2 weeks and am feeling great and I only take a low dose 2 times a week - it's truly my "Fountain of Youth." F 78 36 years
0.45 2X W
8/17/2015
 5  complete hysterectomy at age 32 none at all premarin made me feel like I was alive .since I was taken off premarin I have hot flashes ,night sweats , extremely painful intercourse with my husband who is very frustrated with my situation in the bedroom . I also experience frequent headaches lasting 2 to 3 days at a time . my memory became so poor that it has affected my work performance to the point that I can no longer be a productive member of the work team .physically , my vagina burns ,pains and itches almost constantly . my hair is rapidly becoming so thin , im sure I will be wearing a wig in a few months .never in my life have I had depression . now , I not only see nothing wrong with suicide ,I now view it as the best possible remedy out of a horrible tortuous situation . F 67 35 years
0.625 mg 1X day
7/23/2015
 5  Complete Hysterectomy at age 35 No side effects for 35 years. I felt wonderful. I had a DVT last March and tested positive for anticoagulant. Was advised by 3 Dr's to go off cold Turkey. It's been 3 months off premarin and I feel horrible. Chronic pain, fatigue, and all the symptoms that go along with menopause. I have not been able to work since March. I want to go back on it but scared of the risks. Please email me at jackiebrown628gmail.com with any suggestions F 65 35 years
.03 mg
6/26/2019
Email
 5  Total Hysterectomy No side effects, Feeling great! F 63 35 years
0.3 MG 1X day
7/21/2022
Email
 5  Total hysterectomy at 35 years old. I have had no side effects whatsoever. I am now 75 years old. I can outdo my children. I have no arthritis. My skin looks very good for my age. I have a nice head of hair. My friends thinks I look much younger. My doctor has wanted me to get off the Estrogen many times through the years but I have refused to do so, at one time having to change doctors. If someone has a stroke or heart attack, just because they are taking estrogen, they blame it on the drug. Many people have strokes and heart attacks that have never taken estrogen. I told my doctor that I am not willing to go through a lifetime of suffering just because I may or may not one day have something happen to me, that may or may not be the effects of the drug. There are side effects from any drug on the market. F 75 35 years
1.25 1X day
10/11/2011
 5  Hysterectomy at 28 years old none tried off and on for years to get off of it,(dr. suggestion) even recently going to one every other day. not doing this anymore...I am on it for the duration of my life... side effect when off are much more than when I am on the med. F 65 35 years
.625 1X day
11/12/2011
Email
 5  Total hysterectomy at age 28 I have never had any real side effects .... I believe it even helps me mentally ... I do have swollen ankles sometimes...but that could be due to many things... I did not like the weight gain ... I assume came from the premarin because it effects your thyroid .. I have never had a problem related to premarin ... except the prempro...which effected my eyesight..lucky I figured it out quickly...and my eyesight returned to normal... which I was told would not happen...I feel no one should take the prempro.. .. I've taken regular premarin 1.25 since 1971 ... and feel it keeps me young ... many people compliment me on my youthful appearance ... could be genes ... but it is a fact you have more hormones when younger and better skin.... F 65 35 years
2/4/2006
Email
 5  totaly hysterectomy None I did not mention in my orginal entry.....My surgeons recommended I take the premarin 3 weeks and leave off one week and I have always done this...which is more in tune with your body as before...I have had doctors argue with me...but I maintain the the time elements are important and the surgeons correct...I have done much research on hormones and their cycles... It is not normal to the body to have the same amount of estrogen all the time...progesterone cream is used the last week...just as the body would cycle these hormones... F 65 35 years
2/4/2006
Email
 5  hyster none -- felt good I need it, my hair is thinning on top---HORRIBLE---I need it!!! Also, hot flashes, and vaginal dryness. F 68 34 years
2.5 1X day
6/10/2012
Email
  

PREMARIN  (ESTROGENS, CONJUGATED):  This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).    (Sources: U.S. Centers for Medicare Services, FDA)

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