PREMARIN Reviews (ESTROGENS, CONJUGATED)

Average Rating: 3.4 (505 Ratings)

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PREMARIN  (ESTROGENS, CONJUGATED):  This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PREMARIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PREMARINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  complete hysterectomy none Over the last 10 years I have reduced my dosage from 1.25mg to .625mg daily. My Doctor wants me off completely because heart disease is prevalent in my family. We continue to debate this. I continue to take .625 mg. At age 48 my previous physician told me his 94 year old Mother was still taking Premarin and I should too. 59 37 years
1.25 1X day
6/2/2011
Email
 5  Total Hysterectomy at 30 I have no side effects. I love my Premarin! Becasue my insurance would no longer cover Premarin I tried Estridiol. OMG! Estridiol is a nightmare. I have been on Premarin for YEARS post Hysterectomy and felt fine, off it, I started having hot flashes, weepiness, agitation, anxiety, depression, night sweats, forgetfullness, headaches and feeling just terrible. I have genralized anxiety disorder and the lack of Premarin made it so bad. Premarin made me feel normal. I will start back on Premarin today and hopefully find my old self again. I don't care what it costs, Premarin WORKS GREAT for me. 52 23 years
.3mg 1X day
4/16/2012
 5  osteoporosis none 51 6 months
10/16/2002
Email
 5  hrt (hypogonadism) only good side effects including weight loss ! (BMI was over 30) My symptoms before trying it were : night sweats, muscle pain, osteopenia, high calcemia, high T4/TSH, libido decreased. I'm intersex (delayed puberty due to low LH-hCG bioactivity, partial gonadal dysgenesis) 41 12 weeks
4/18/2008
 5  Total hysterectomy aged 26yrs Nil side effects. Now aged 72 yrs gained weight. 1.25mg for 45yrs now .625mg occasionally flush at aged 72yrs. I look years younger and have no wrinkles and smooth skin... Premarin is a wonderful estrogen drug..Gynecologist says stay on it because of the long period of 46yrs..when I reduced dosage had slight side effects example flushes. 72 46 years
.625 1X day
9/8/2020
Email
 4  
5/10/2005
 4  
9/4/2005
 3  
2/7/2005
 3  Dry Vagina - itching in genital are
9/17/2009
 5  menapause/osteo migraine, but this is genetic and based on the normal hormonal cycle anyway for members of my family. I had no side effects and felt wonderful. Full of beans, fit and healthy. Last year I did have abnormal cervical cells which were checked OK. Being checked again shortly. Just recently taken off premarin by doctor after increase in BP after heavy stress at workplace, and prescription availability problems on NHS. Put on Femoston. Suffered night leg cramps, aching, dizziness, dulling of brain, nearly had a road accident and I cannot sleep anymore because of the cramping of my legs, which also have sensations like insects crawling over my skin, and assorted sudden pains everywhere. I want my premarin back! I'm off to the doctors to sort things out. Love it! F 64 15 years
8/20/2009
 5  To stop menopause migraines at 45 I'm a DES daughter - had female problems all my life. Started getting terrible headaches at 45 -stress, divorce, weight gain etc. Doctor put me on highest dose Premarin. Now, after slowly decreasing to 0.3 a year ago (total hysterectomy + Ovaries 6 years ago) I feel and look great. I work out and hike, lift weights, would like to be 10 pounds thinner (5'9" and 155 lbs) but skin is gorgeous and hair thinning slightly but OK - cut it into a nice, young style. I am thinking of going off completely 0.3 mg daily dose but fear headaches returning and I am a writer - can't afford to miss work like I did before starting Premarin. I can take hot flashes, but not Menopause Migraines! My only sister is a year younger and has Stage 4 breast cancer...a survivor for 8 years but not athletic and not a positive thinker. I don't like paying $45 per month for Premarin but bone density scan 2 years ago and heart test last year show I am in excellent health - bones of 35 year old. Lift weights, ladies! Vaginal dryness but Astrolube solves easily. Don't want to quit Premarin if daily quality of life would decline. F 56 11 years
9/16/2008
 5  Total hysterectomy age 44 Mostly side effects when I didn't take it. Intense crying episodes. I do have concerns about it with the breast cancer thing..but do not know of any negative side effects Initially took 1.25 decreased to 1.0 & 6.0 over time now taking .3 every other day for 2 years. F 68 20 years
4/26/2009
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 5  hot flashes none I just afraid of the cancer threats with taking this medication. F 55 4 years
3/30/2009
 5  complete hysterectomy at age 40 None at all! I stopped for awhile when all the scare studies about estrogen came out then asked to go back on them after a couple of years of horrible hot flashes and depression. I feel great with the low dose of this pill. Take it, it works! F 56 16 years
3/26/2008
 5  Symptons of Menopause None yet. F 54 5 days
11/19/2008
 5  hot flashes, night sweats None. Possibly big weightgain but who knows? It's the PROVERA that's the poison; not this. The Womens' Health Initiative used Provera or Prempro. I take this ALONE and have 0% hot flashes. I cannot live without my sleep, period. Raising my grandson. First week of the month I stop. F 64 20 years
12/1/2008
 5  Had a total hysterectomy I don't believe I have had any negative side effects. I was told I would gain weight after my hysterectomy, and I am heavier then before the surgery and taking Premarin. However, I have been able to lose weight by following Jenny Craig, so I don't believe the weight gain is from either. At age 40, I had a total hysterectomy (both ovaries and uterus)due to Endometreosis. After surgery, I was immediately given a hormone injection, then started taking Premarin. I often get compliments on my great skin and most think I am at least 10-yrs. younger then my 57 years. I do not have a history of breast cancer in my family, and watching my Mother develop a hump on her back by not taking any HRT after her menapause, I have made the concious decision to stay on Premarin 0.625 and have a great quality of life, unlike some of my friends who are scared to death to use it and suffering. In the end, it is a personal decision, everyone's bodies react differently to meds, and based on each individual's family history and life choice. One more plus, I have same libido as prior to surgery/Premarin and experience no vaginal dryness, so no need for vaginal creams, gels, etc. F 57 18 years
1/21/2009
 5  total hysterectomy I gained weight on the 1.25 when my MD cut them in half to .6 I lost it right away. 5 yrs later my MD rotated me between .6 and .4 and I did that for a yr and now she's wanting me to take the .4 full time. I agree- everyone says I have great skin- I think it's gebnetics tho' Polish/german both sides and my folks still lokk 50 and they are in their 70's F 52 10 years
1/26/2009
 5  Hysterectomy For the first few years, I gained weight, but I also ate a lot more. Occasionally, I have had problems urinating, but that goes away when I skip a day on the pill. I am 65 and have been on the drug for 22 years. My doctor wants me off of it, and I did wean myself down to 3 pills at .6 mg a week. After six months, my skin is crepey and dry. I aged 10 years in those 6 months. Last week, I resumed daily use and feel much better already. I'll probably do five days on and two off at least until I am 70. I can find NO statistical data proving a link between estrogen-only usage and breast cancer. The data is all linked to estrogen-progesterin (which I refused to take 22 years ago after reading how unfavorably the Europeans were to it even back then). I think it's human nature to blame something when we get a disease. Premarin alone may or may not cause breast cancer, but the data just isn't there in my opinion. Quality of life means something here. My breast friend got a vicious form of breast cancer at 68 and she has a complete hysterectomy and NEVER HAD HORMONE THERAPY. So who knows? F 65 22 years
10/24/2007
 5  total hysterectomy I coulden't sleep after having my hysterectomy so doctor put me on .625 premeran apex three weeks after surgery. I go off of it on the 25 of the month and start again on the first. I heard it was not good for you to be on premarin very long so apex 5 mo ago I started splitting mine in half. My hair is falling out my head is sore and have been having more cramps. I am 5.2 and weigh 135.I have not had any complications except my hair. I feel great, play golf and do yoga. I am going back to taking my.625 premeran. F 77 25 days
1/20/2008
  

PREMARIN  (ESTROGENS, CONJUGATED):  This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).    (Sources: U.S. Centers for Medicare Services, FDA)

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