There are 272 ratings for the drug: PREMARIN in the Askapatient database.

Key to ratings for premarin: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine.

Page: 1  2 3    Results are sorted by Date Rating Was Added.

Rating	Reason	Side Effects	Comments	Sex	Age	Time Taken and Dosage		Date Added
				F  M
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5	Hysterectomy	NONE	I have been taking premarin for 27years and would not stop taking it no matter what anyone said. I have tried to stop thru the years but it always ends up the same. I start having hot flashes, bad headaches & just feel miserable, so I always end up going back. I alway used 1.25 which is a very high strength in the last year or so I have cut back slowly to about 1/2 that amount, if I try to go any lower I start back with all the same symptoms. I have had a much better quality of life for taking it.	F	61	27 years 1.25 1X D		2/8/2010 Email
5	total hysterectomy	None except possible link to migraine headaches.	Since my hysterectomy, I have continuously been on Premarin 0.625 until three months ago, when I stopped due to possible link to migraine headaches. During that period, I have felt terrible, although my headaches lessened. It must be noted that I also STOPPED the use of my favorite food in the world, CHOCOLATE. Not sure which contributed most to the headaches being less, but the premarin cessation has caused sleeplessness, irritabilty, crying, loss of memory, depression, sense of impending doom,sweating, dry skin, lack of concentration and feeling like an old lady. Two days ago, my doctor recommended that I go back on the Premarin, which I did and noticed a dramatic change in all the above symptoms, especially the horrible hot flushes throughout the day. I will stay on this medication. Since I work in the medical profession, I am aware of the propaganda the drug companies produce (presented as education)to sell their wares. Do not believe everything you hear. Do research on it for YOURSELF. Everybody is different and everybody's BODY is different. No one can reliabibly predict side effects, since chemistry is too varied and individual. The side effects and disclaimers are simpley to protect the interest of the drug companines against laws suits. I encourage anyone taking Premarin to do research for themselves and listen to that inner voice about this medication. It's not for everyone, but it is for ME.	F	65	15 years		1/27/2010 Email
4	Hot flashes	None	I started menopause at age 40. I have tried soy supplements with no help for my hot flashes (every 45 minutes) I am trying to go off due to cancer concerns but the quality of life isn't worth it. Has anyone tried Amberen?	F	59	15 years		1/21/2010 Email
2	hystererectomy	Just did'nt feel right. going to the hospital lose of weight to much weight loss.stomach pain. crippling leg pain and lower back pain. ischemia colitis 3 blood clots in colon. i had to be rush to the hospital for was bleeding so much.i was told in the hospital that it was taking estergen.	took premarin for 13 years 6.25.felt great, slept good, hair and skin looked great. I stopped taking it 2006. now i am very tired, skin very dry, feel old, irritable hard time sleeping. try to go back on it a last year my gyn said that my estergen level very low and needed to be on some kind of estergen. tried other estergens bad side effects try premain but got back side effects head hurts stomach pain always hungry. had bad hunger pains. i do miss taking premarin but i don't know if i will every go back to taking it.	F	53	13 days		12/22/2009
3	still deciding on taking it!	none yet	I had a total hysterectomy several years ago and then within a few years I had to have my left ovary removed. Then within two years my right ovary was bad so I waited till 12/10/09 to have it removed along with a mass where my left ovary use to be. I now have nothing inside and I also did a bladder sling. My doctor wants me to start taking 1.25mg Permarin but I feel ok. Should I take it. I am 32 years old. Im not sure! I dont think I should start out that high of a dose. Any advise?	F	32	0 days		12/16/2009 Email
1	menopausal symptoms	I was thinking of taking this for night sweats and palpitations but decided against it. I had taken it approx 10 years ago for about a week but stopped because I felt so bad. I started feeling severly depressed and developed edema. In one week I gained 10 lbs!!	After reading all the posts on here I decided to do some more reseach. One of the books I read was "America Fooled" which discusses HRT. Dr. Peter Breggin has also written books discussing drugs and includes HRT I found that a lot of doctors will dispense antidepressants and anxiety drugs during menopause and now know (after reading Dr. Breggin's books) that these not only come with side effects/adverse reaction but can be dangerous. I will NOT be taking this medication.	F	53	7 days		12/13/2009
5	cancer related had a Hysterectomy	No side effects at all....if I go off the pills I feel horrible. I have been on premarin for 14yrs		F	47	14 years		12/11/2009
1	Total Hysterectomy	Unresolved Peripheral Edema. Been off the medication now since October. They switched me from Premarin to Estratest to Climara and currently off of all HRT till after cardiac testing is done. Never had a single problem with edema or anything till starting this medication. Have been told that the problems will never resolve. Went from 144 lbs to 167 lbs. Bra size 36C to 40DD! Unless anyone wants the benefits of extra large breast then I would suggest they stay away from the medication. Or FDA should get off their A$$ and figure out why it causes this is some women and some women it causes no issues. There is a missing link somewhere. They just need to take the time and figure it out! Spoken from a licensed NURSE mouth!		F	37	5 months		11/29/2009
5	total hysterectomy	tried bioidentical because they were to be so much better not, after several months of chest pain ,heart palpatations, increased blood pressure and increased pulse rate I went back to Premarin and all those side effects went away, will not change again.	Do not be fooled by bioidenticals if you have any heart symptoms could be that. I have not had any problems since going back on Premarin.	F	41			11/22/2009
5	hysterectomy at 45	I've never had a side effect.	The doctor suggested I stop taking it and immediately felt horrible. I also gained 10 pounds & my blood pressure went up. I've never been on blood pressure medicine but now I am. I went back on premarin & now have a GYN appointment to fight for my right to remain on it. I know the risks but there are risks in everything - this works for me.	F	64	19 years		11/10/2009 Email
5	Total hysterectomy at age 26	I bled for 8 months straight. Very heavy with huge clots. None of the meds that was prescribed worked. I had to have everything removed except for one ovary. I went for 8 months not taking any kind of hormones. The doctors were hoping that my 1 ovary would kick in and work. But it did not. My body began to swell and just touching my body anywhere with the slightest pressure caused me great pain. I was then put on Premarin. The swelling went down, no more pain. I have been on it since 1986. My doctor wanted to lower my dosage. We did and all the pain and swelling came back! And we tried this over the years several times. Always came out the same with the same results...all BAD!. I told her that I will stay on it for life. I will not go through that again!!		F	49	23 days		10/10/2009 Email
1	hot flashes,depression	Hot flashes increased,leg cramps,nausea,severe heart palpitations,dizziness,confusion,extreme fatigue (in bed all weekend)	This is an awful drug..and I was only on it for three weeks! I had such bad side effects that I had to go to the ER (thought I was having a heart problem)..and I cannot afford this. I am still really sleepy, 3 days after stopping.I would never recommend this drug...there are better alternatives. My MD says all these problems were not related to the 0.625 mg. Premarin...but why do I feel better,since stopping???	F	53	21 days		10/7/2009
1	Haven't started yet, and won't now	Terrible hot flashes. Night sweats, mood swings, depression, ect.	I had a hysterectomy in 2001 and has been dealing with all of the terrible symptoms since 2003. Last week I decided to maybe try Premarin after being pushed for years by my Doctor to at least try the smallest dosage,0.3MG. I filled the RX but after reading all of the negative press I'm slam dunking them like right now. I have managed for all these years, might as well keep on.	F	52	0 days		9/30/2009
1	DESPERATE..TYRING AS MY LAST OPTION	I have suffered most of the side effects severly already ...can it really get any worse than ready to stand in front of a moving train ??? if yes.., then its death by chocolate and champagne 24/7 Started "Premanin today !!! ((((praying for some glimmer and SAFE return of the once sane happy capable woman and life in me)))) .....I'm in total contradicted FEAR :(((...BUT ITS ALL I HAVE LEFT. THAT I HAVE NOT TRIED !!! However my deep emotional logical FEAR is gripping me, as my younger sister and aunt have had and survived breast cancer. If only there was a successful clear and simple way to simulate balance our own hormone producing glands.........but every woman's body and life paths have set personal patterns which are almost impossible to unravel pinpoint a clear pathway to true hormone balance and health throughout our life. Have other Women out there felt this bad and in FINAL DESPERATION go directly against ones own logic FOR SOME SORT OF QUALITY TO LIFE ...having to fin	I'm 54 now with very *Low estrogens, *MENO-INSANE, very unhappy, single(no interest in a partner) overweight not from eating too much, unfit, chronically depressed, aging rapidly, feel like a cold fat unattractive vegetable, cannot concentrate or work with little interest clarity, poor memory, un sociable, lost confidence, no motivation for anything or positive outlook, always very tired fatigued.....feeling like everything has shut down, body has just given up, crashed, stoped with no fuel left, train wreck, Elvis has left the building :(((. (At 50yr I finally sarcome to a Hysterectomy leaving one ovary after battling multiple fibroids, very *High estrogens dominance, years of heavy emotional stress fatigue. However felt I was still quite intelligent,kind caring, creative talented, hard worker,outgoing with a real zest, strong assured confidence, quite attractive slender feminine nice body, thick hair, thoroughly enjoyed fulfilling sexual intimacy rewarding life) Now I have spent all time efforts money on naturopaths health supplements advise talking listening reading studying comparing......now in my final desperation worn down/out, have finally given into dreaded *Premarin .625mcg that I SAID I WOULD EVER TAKE ( my mum in desperation seeing me try so hard with everything natural and suffer much for so long finally took THE *P SCRIPT ( I had kept for my last and final desperate measures ) to the chemist today and filled it for me, she with hope tears and hug just try it	F	54	1 days		9/26/2009 Email
3	Dry Vagina - itching in genital are							9/17/2009
5	Total hysterectomy at 39	I had no side effects and had taken it for 25 years! .065 dose. My doctor took me off of it about 1/1/2 years ago, as he said they believe it increases blood pressure. High blood pressure runs in my family anyway, but I do take medication for it, its borderline.Since stopping premarin, I have terrible hot flashes, hair loss and getting flabby around the middle, despite my working out, and more hair on my face. I am going back to the doctor tomorrow and want to go back on it.	I never gained weight from premarin and I am going back on it!!!!	F	66	25 years		9/8/2009
1	will not, take plant-based hrt		i don't understand how so many women could blithely take this drug that is produced from so much suffering and death from the premarin mares and their foals. there are other hrt's that are produced without the awful impact of this drug. and lobular cancer is associated with taking of premarin.	F	54			8/29/2009
5	menapause/osteo	migraine, but this is genetic and based on the normal hormonal cycle anyway for members of my family. I had no side effects and felt wonderful. Full of beans, fit and healthy. Last year I did have abnormal cervical cells which were checked OK. Being checked again shortly. Just recently taken off premarin by doctor after increase in BP after heavy stress at workplace, and prescription availability problems on NHS. Put on Femoston. Suffered night leg cramps, aching, dizziness, dulling of brain, nearly had a road accident and I cannot sleep anymore because of the cramping of my legs, which also have sensations like insects crawling over my skin, and assorted sudden pains everywhere. I want my premarin back! I'm off to the doctors to sort things out.	Love it!	F	64	15 years		8/20/2009
3	MENOPAUSE	WEIGHT GAIN (15 lbs.). UNABLE TO LOSE WEIGHT DESPITE DIET AND EXERCISE. MY SKIN AND HAIR WERE GREAT PLUS NO NIGHT SWEATS AND WAS ABLE TO SLEEP. LESS HEART PALPITATIONS.	ALTHOUGH IT WORKED ON ALL MY MENOPAUSE SYMPTOMS, I COULD NOT STOP EATING (THIS STATED AT THE EXACT TIME I STATED THE MEDS). AND IT HAD RAISED MY BP SLIGHTLY BUT NOTICEABLY. ALSO HAD MORE UTI'S AND PAINFUL BLADDER WHEN FULL (NOT SURE IF THIS IS RELATED - BUT I HAD A NAGGING FEELING THAT IT DID). AM THINKING OF GETTING OFF DUE TO ALL THE NEGATIVE INFORMATION ON THIS MEDICATION.	F	53	6 months		7/29/2009 Email
3	Complete histo-	I was worried about heart disease and cancers so against my Dr's advice, I stopped my .675 Premerin dosage. I was fine at first, then, maybe two months later, I started really feeling it...terrible hot flashes, brittle nails, lots of hair loss. Maybe I should go back on?? I have been bruising very bad on legs and feet. Breast cancer runs in our family. I am trying Estroven..first day is today. Hopeful!	I think more info should be available...more options also. Not just our doctors pushing manufactured drugs b/c of the drug companies and the money they pay.....	F	37	18 months		6/14/2009 Email
1	total hysterectomy	Horrible leg swelling, then whole body swelling after only 7 days on prescription. Ending up in ER to rule out DVT, on diuretic for over a month now trying to get edema under control. Will never touch hrt again, prefer to wake up sweating numerous times a night. Dr didn't recommend, I had asked for hrt since I had gone without for over a year since sx and the sleepless nights were getting to me. I have decided I can live without a full nights sleep.		F	47	7 days		5/16/2009
5	Total hysterectomy age 44	Mostly side effects when I didn't take it. Intense crying episodes. I do have concerns about it with the breast cancer thing..but do not know of any negative side effects	Initially took 1.25 decreased to 1.0 & 6.0 over time now taking .3 every other day for 2 years.	F	68	20 years		4/26/2009 Email
2		Hot flushes,trouble sleeping, weight gain, hair loss,breast pain,nervousness,facial hair.	When I first started taking it I felt fine but now 13 years on the side effects are increasing especially hair loss which I am finding very distressing.	F	52	13 years		4/20/2009
4	total hysterectomy aged 32	i was given a total hysterectomy at 32 after years of suffering severe pain due to endriometrious .i would total recommend this type of hrt apart from a little weight gain which could be age or diet related anyway , my hair skin and health are better than they have been throughout the earlier part of my life .	i feel this is a very good hrt and ive been very happy with it .	F	44	11 years		4/2/2009
5	hot flashes	none	I just afraid of the cancer threats with taking this medication.	F	55	4 years		3/30/2009
4	Total Hysterectomy	weight gain-15 lbs., tingling, joint pain, stiffness and exhaustion	I can't afford night sweats due to diabetes-and know Premarin helps me look younger, I have tried going without before and didn't like results. I take insulin and synthroid so am confused as to whats causing what. Have been on .625 Premarin-after reading posts I will try and decrease the Premarin to see if any improvements. Sugars and thyroid tsh are great.	F	55	17 years		3/20/2009 Email
1	Total Hysterectomy	44 yr old, normally in great health. After 1 year on Premarin I began to have constant pain, throbbing and swelling in my legs. I suffered for months. I suspected that the HRT was the cause. Finally I decided to stop the Premarin and within 4 days of stopping the meds all leg symptoms were gone! I will NEVER EVER take this med again.		F	44	12 months		3/17/2009
3	total hysterectomy kept ovaries	I have gained 12 lbs. in 3 years-swollen breasts,spare tire and fat around the stomach-feel very bloated and retain water.I have always been normal weight and no excersize helps the weight around the middle.	I had very bad hot flashes,chills,weepiness and anxiety after my hysterectomy. My Dr. said I still wasnt in menopause -still producing estrogen at first. Tried soy and herbal remedies-they helped reduce the hot flashes a bit for a while but I still felt very nervous and like crying all the time. Finally got the courage to try Premarin-dr. said it would help and the awful hot flashes stopped. I feel somewhat better mentally. I cut .45 in half and take it daily but wonder if the full dose would be better. Cant stand the weight GAIN. always had been slim.It does keep you looking younger I think-my skin is much smoother and younger looking than a friends who never took hormones. I worry about breast cancer but quality of life is better while on Premarin so I guess its worth the risk.	F	60	3 years		2/26/2009 Email
1	hysterectomy	I had been on Premarin 1.25 for 21 months. Everything seemed to be going well, yes I put on 45 lbs but thought it was the hysterectomy. In August I started having severe foot pain and unbearable leg cramps. I bought several pairs of shoes trying to relieve the pain. Numerous trips to the doctor, all kinds of blood work, and on and on. I was in so much pain with horrible swelling the last month I could no long stand it. I started a Chiropractor and again nothing helped. The doctor had thought it was a blood pressure medication they had me on for high bp, I stopped taking it but the horrible pain and edema continued. Finally one morning I said "I am going to stop taking the Premarin, and you know what the swelling left, the pain in my legs were gone, and I felt great. I told the Doctor I had quit the premarin and he said he didn't think it was that but it certainly worked. He gave me HRT patches to wear but I am not starting them unless hot flashes begin. I can not tell		F	51	21 months		2/24/2009 Email
4	Total Hysterectomy - Age 38	Slight Memory loss (but always been a bit scatty!), mood swings, a little weight around my belly	I can honestly say since having my hysterectomy and taking Premarin (1.25mg now - the lower dose originally made me feel very tired) I have felt so much better. Having suffered since my early 20's with endometriosis and adenomeyosis I feel rejuvenated. My skin is glowing and I look and feel great. Lucky to conceive twins at the age of 37 with the help of IVF, I have a pain free life and the slight side effects are a small price to pay and do not worry me. I feel pain free for the first time in 15 years and enjoying my fantastic life.	F	40	2 years		2/17/2009 Email
4	Total hysterectomy at age 25	none	I had to have a full hysterectomy at age 25. I dealt with some depression as a result of it. I dont feel that the pill caused the depression, I think it was just me getting usto the idea that I will never have the possibility of having a child of my own DNA. I thought it may have ben the drug causing my depression so i quit taking it. I received sever hot flashes and mood swings. Once i started taking the pill again, I leved out. I would like to warn younger people who have had their ovaries removed thinking of quitting hormone replacement. Please consult your Dr. before stopping, your risk of developing osteoporosis is greatly increased. The benifits greatly outway the risks for me having to take hormone replacemnt at such a young age. I am no Dr. but thats what my Dr. told me.	F	28	3 years		2/13/2009 Email
1	Hot Flashes and Bone Concerns	Increased my eating habit which lead to weight gain 13 lbs in 7 months. Sleepiness and fatigue. Very sore breast.	Although it took away the hot flases this pill has to many dangerous side affects. If you are considering this medication please read side affects very carefully. I would never recommend to anyone.	F	50	7 months		2/8/2009
4	Totaly hysterectomy on 1/29/08	Total hysterectomy due to endometriosis, bleeding in fallopian tubes and cysts on my ovaries. After that I experienced dry skin, aches in shoulder & knee joints, and hot flashes. My body suddenly felt very old. Sexual feelings/urges were completely gone. I felt like I'd been castrated, it was so apparent that a part of me was missing. After 2 week follow-up appt, the MD placed me on 0.625mg of premarin. However, the physical problems persisted. In my 3 month follow-up visit, I asked for an increase in dosage and the MD changed it to 1.25mg. The problems went away in 2 days and I felt normal again. But in the following 3 months after my 2nd appt, I gained over 30 lbs!!!	I have concerns about the abuse of mares in the maufacturing of Premarin. I'm also greatly concerned about it's risks for causing heart disease, breast cancer, etc. But even though I'm fat, I feel more normal and able-bodied with the Premarin, than without it. Still, I'm thinking about asking the MD to lower the dosage one notch just to cut health risks and see how my body adjusts. And I'm trying to take off the weight.	F	48	1 years		2/6/2009 Email
3	hysterectomy	bloating weight gain acne	took away hot flashes	M	52	10 years		2/4/2009 Email
5	total hysterectomy	I gained weight on the 1.25 when my MD cut them in half to .6 I lost it right away. 5 yrs later my MD rotated me between .6 and .4 and I did that for a yr and now she's wanting me to take the .4 full time.	I agree- everyone says I have great skin- I think it's gebnetics tho' Polish/german both sides and my folks still lokk 50 and they are in their 70's	F	52	10 years		1/26/2009
5	Had a total hysterectomy	I don't believe I have had any negative side effects. I was told I would gain weight after my hysterectomy, and I am heavier then before the surgery and taking Premarin. However, I have been able to lose weight by following Jenny Craig, so I don't believe the weight gain is from either.	At age 40, I had a total hysterectomy (both ovaries and uterus)due to Endometreosis. After surgery, I was immediately given a hormone injection, then started taking Premarin. I often get compliments on my great skin and most think I am at least 10-yrs. younger then my 57 years. I do not have a history of breast cancer in my family, and watching my Mother develop a hump on her back by not taking any HRT after her menapause, I have made the concious decision to stay on Premarin 0.625 and have a great quality of life, unlike some of my friends who are scared to death to use it and suffering. In the end, it is a personal decision, everyone's bodies react differently to meds, and based on each individual's family history and life choice. One more plus, I have same libido as prior to surgery/Premarin and experience no vaginal dryness, so no need for vaginal creams, gels, etc.	F	57	18 years		1/21/2009
4	Full Hysterectomy	None I can directly blame on this drug. Did have weight gain but this was most likely due to inactivity after operation. My libido is fantastic and I'm looking good for my age.	Enforced Hysterectomy at 39. Been taking 1.25mg for 10 years. MY SANITY SAVER. My doctor wants to take me off it due to high blood pressure and the length of time taking premarin I am fighting to stay on premarin.	F	49	10 years		1/20/2009
1	total hysterectomy	Pain everywhere. in knees, legs,hips restless leg syn	I was put on premarin following hysterectomy just to make up the oestragen and to offset menopausal symptoms after op. I never experienced hot flushes or anything like that but when the scare came in about breast cancer my doctor took me off premarin 18 mths to 2 years ago having taken it for 11 years. I felt absolutely terrible, anxious and nervous all the time, not wanting to go out. So he put me back on it and now I find I have breast cancer. Surgeon reckons Ive had it 18mths or so and the tumor was very oestragen receptive. I did not realise this medicine was made from mares urine and doubt I would have taken it if I had known. But the way of the internet enables me to look things up now. I didn't connect the joint pain with the premarin but now I am off it I have realised it is not so bad. I've been off it three months now and have started hot flushes, but have to get rid of the cancer so have no option.	F	57	13 years		1/9/2009
4	lichen sclerosis	weight gain (?), breast tenderness	premarin HAS helped my lichen sclerosis although i don't like the idea of being on it long-term.	F	34	10 months		12/31/2008
3	oopherectomy	Breast tenderness , heart palpitations ,	I choose premarin over estradiol . after my sergury I was put on premarin 1.25 .I did get some side effects at first. sore breast, leg cramps , then I heard all the bad side effects premarin will cause .so I got nervous I asked my doc to put me on a bio-identical hormone .I was put on estradiol in fear I would get breast cancer or something from premarin. After taking estradiol for 6 months now I have aged at least 5 years. my skin is loosing its elactisaty my hair is thinning and I still got the side effects as I did when I was on premarin . I went back to my doc and i told him that when I was on premarin I at least had energy my skin looked soft and glowy . As for the bad side effects I felt when I was on premarin It was because the dosage needed to be ajusted .Just like with any med. the scary thing is ladys if you only new what goes into 90% of the meds on the market and the side effects and risk taking them, Its scary . even most of the the food we eat is saturated with pestiside	F	40	2 days		12/29/2008
1	menopause , bone health,etc.	The #1 Side effect was peripheral edema, which fluid retention in the legs. This is horribly painful. The fluid does not disappear overnight when you stop the drug, it takes months. Additionally, I had extreme anxiety and mood swings.	Wow, my health has never been this bad,never. There is no doubt this drug is toxic to my body.	F	53	2 days		12/9/2008
5	hot flashes, night sweats	None. Possibly big weightgain but who knows?	It's the PROVERA that's the poison; not this. The Womens' Health Initiative used Provera or Prempro. I take this ALONE and have 0% hot flashes. I cannot live without my sleep, period. Raising my grandson. First week of the month I stop.	F	64	20 years		12/1/2008
1	Total hysterectomy	Weight gain 30 lbs..mental fogginess, forgetful, depression, joint pain, swelling. Insomnia..	I was put on HRT after total hysterectomy 3 yrs ago. I didn't see any change initially, but started on a patch which my skin couldn't tolerate (rash). I have aged probably 10-15 yrs. My skin looks horrible..have a tire around my abdomen and have blotchy/brown patches everywhere. I never had weight issues, have been very active. Always had a flat stomach (even after birth of twins!) I have recently had a saliva test done, and have found I have adrenal fatigue. My recommendation is to find a doctor that uses bioidentical hormones and get tested ASAP. We are in process of weaning my dosage, will try to repost with update.	F	42	3 years		11/29/2008 Email
5	Symptons of Menopause	None yet.		F	54	5 days		11/19/2008
5	abnormal uterine bleeding	none	1 pill for 21 days each month.	F	48	3 months		10/25/2008
2	Hystorectomy	chest pain, hair loss, severe joint pain expecially in knees, anxitey, weight gain, blurred vison, headache, and trouble sleeping.	I have been on this medication for 7 months now and I just realized what was wrong. I am no longer going to take this medication. Would not recommend this at all.I thought I had injured my knees they hurt me so bad.	F	29	7 months		10/21/2008 Email
5	Menopause	None what so ever.	Doctor has me on .3 mg 25 days on, 5 days off. After one and one half month the hot flashes have disappeared and I can now get a full nights sleep. I no longer go from hot sweat to refrigerator with no in between. It was awful. I tried everything under the sun and got fed up. I had hyst. at 40, kept ovaries. The symptoms took 1 1/2 months to fully go away (you have to be patient). Still need the fan on sometimes. Do not need progesterone due to no uterus. Got three month supply through mail in with insurance coverage and costs $30 per month.	F	52	45 days		10/12/2008 Email
3	Hot flashes	Right after taking the .45 dose of Premarin, my appetite increased, I gained over 10 lbs. in the stomach, butt and thighs and no amount of exercise or diet change has helped take it off. I've been on the Premarin for 3 months and have gained 10+ lbs., my hair is breaking off and thinning and I have no energy to do much of anything. As I was a fairly active (hyperactive:) ) person before, I attribute the lethargic moods to the Premarin.	If I can get past the unsightly weight gain and the thinning hair, Premarin has totally wiped out the hot flashes and sweats and that was the goal, but I am considering going off of it as the weight gain is grossing me out!	F	52	3 months		10/9/2008
4	Hysterectomy/Oophermectomy	WEIGHT GAIN, sore breasts	When surgical menopause hit me in the face, it was ugly. Hot flashes, night sweats, insomnia, weepiness, depression, low low body temp, constantly shiivering, just wanting to crawl out of my skin. I tried over the counter herbal remedies, nope- did not help. So I had to try Premarin or stand in front of a train, that's how awful I felt. I started on .625 of it, and felt a huge relief in a matter of days. I did notice that after a week or so, my stomach was a big bloat- like a full tick! Then my breasts were quite full (I'm basically a flatsy) they also hurt, kind of like I was going to get my period, my whole demeanor was that of PMS queen, but I knew I wasn't going to get my period, so I started to take one pill every other day, and some symptoms were alleviated. I now take .32 every other day, my hot flashes are somewhat more frequent, but the other symptoms aren't back, so that's good, I do hope this will allow me to lose the 18lbs I have gained, I eat low carb, and exercise a	F	42	6 months		10/8/2008 Email
3	complete hysterectomy at 27	since starting the premarin at a dose of .9 mg 3 months ago i am a totally different person. i am so angry most of the time and dont know why. i have put on 10 lbs and my hair is thinning. i get really bad headaches and some times have a problem remembering things. i am not sure what to do at this point. the doctor says to give it time		F	28	3 months		10/7/2008 Email
1	Complete Hysterectomy Dec. 22, 2006	Very painful joints and my right hip something terrible, very moody and had little patience, felt like I wasn't in control of my life. I have been off of the Premarin for almost 3 weeks and I feel better, I have very few hot flashes and seem to be happier. I started taking 1.25mg and before I quit taking it I was taking .625mg. I'm glad I quit. I had also gained weight around my middle that I am hoping to lose soon.	I would not recomend this medication to anyone.	F	38	20 months		9/29/2008 Email
5	To stop menopause migraines at 45	I'm a DES daughter - had female problems all my life. Started getting terrible headaches at 45 -stress, divorce, weight gain etc. Doctor put me on highest dose Premarin. Now, after slowly decreasing to 0.3 a year ago (total hysterectomy + Ovaries 6 years ago) I feel and look great. I work out and hike, lift weights, would like to be 10 pounds thinner (5'9" and 155 lbs) but skin is gorgeous and hair thinning slightly but OK - cut it into a nice, young style.	I am thinking of going off completely 0.3 mg daily dose but fear headaches returning and I am a writer - can't afford to miss work like I did before starting Premarin. I can take hot flashes, but not Menopause Migraines! My only sister is a year younger and has Stage 4 breast cancer...a survivor for 8 years but not athletic and not a positive thinker. I don't like paying $45 per month for Premarin but bone density scan 2 years ago and heart test last year show I am in excellent health - bones of 35 year old. Lift weights, ladies! Vaginal dryness but Astrolube solves easily. Don't want to quit Premarin if daily quality of life would decline.	F	56	11 years		9/16/2008
4	hysterectomy	hot flushes	I was on Premarin for 15 years, I decided to come off of it, I did it gradually, for 3 months I took one every other day, and then for another 3 months I took one every 3 days, and gradually to 1 a week until I finally stopped and it worked no more symptoms, before on premarin, I was aggressive, depressed, my stomach was bloated, I put on weight, my hair was getting thin, my legs were stiff and I was breathless, I am 65 and feel much better now that I am off of it. If you want to stop taking it, you have to do it gradually or your symptoms return with a vengeance.	F	65	15 years		9/2/2008
4	Post-Op Transgendered Woman	I dont produce estrogen or testosterone. So, I only need a very low dosage..a .3 mg every other day. I have taken estradiol for 4 years, and premarin for 6 years now, and I have found that premarin is better for two reasons. Premarin is a lot more potent than estradiol, especially the "half-life", or how long it stays in your body. If my dosage isnt just right, I would have all the side effects that everyone has mentioned! I have had all those symptoms, and simply just started to do all the research, get my blood levels checked, and ween down to a lifetime, best maintenance dosage. I rated it a 4, because of two reasons. One, its more conveinent to take than estraidol is. You would have to take estradiol twice a day, because the "half-life" is only around 3 hours for estradiol, compared to around 15-20 hours for premarin. You just have to make sure to take the lowest dosage that you actually need. Premarin is potent..much more ptotent than estradiol! You will only h	I have done lots and lots of research about hormones, vitamins..etc. I am a Post-Op transgendered woman..since oct. '03. I dont produce estrogen, or testosterone anymore, and my lingering amount of testosterone is constantly at around 17 ng/dl, which is very, very low for a female. So, I only need a tiny amount of premarin(estrogen) now, and its just for bone density/maintenance dosage(.3 mg every other day). There is some research that people arent doing here, and I want to explain this. First, estrogen therapy increases copper levels in the body. Estrogen, and copper levels parallel with eachother. Zinc, which is an atagonist of copper, and the opposite of copper, should be increased if on estrogen therapy!! If you are having blurry vision, joint pains, libido problems, acne breakouts, thinning hair, colds/flu..etc, its most likely because you are high on the copper side, and low on the zinc side. You should be at a level of around 12 mg of zinc, to 1 mg of copper ratio for optimum h	F	40	10 years		8/9/2008 Email
4	Total Hysterectomy	Some depression	It has been great for me my doctor had to adjust my dosing after that i have been good.	F	30	4 months		7/30/2008 Email
2	total hysterectomy & oophrectomy	Just not myself.Tired and unmotivated. I have put on weight(5kg)which is mainly due to overeating,but I am excessively hungry.I have a constant dull headache & no libido what-so-ever.My skin feels dry & itchy and I am irritable with everything & everyone.	I have tried reducing dose from 0.625 to 0.3 and also tried patches, but to no avail. Do I feel like this as a result of Premarin or the loss of my ovaries?	F	55	8 months		7/24/2008 Email
2	Emergency Total Hysterectomy	Fluctuating weight, headaches, severe aggression, mood swings, anxiety, tearful, depression.	In the year and a half since I have been taking this drug, my personality has changed considerably. I have become very aggressive to the point of losing control of my actions. This drug does not suit me, and in my opinion, has made me worse.	F	36	1 years		7/17/2008 Email
1	Total Hysterectomy	I became so nervous I constantly felt like wanting to jump right out of my skin, and on top of that I also became so angry I could have eaten people up! That's the total opposite of the kind of person that I usually am.	Had to quit. Coped with hot flushes for a few years, and more recently with bone loss but, hey, it's life! I now take calcium every day, but I never feel that horrible tension and anger I felt while on this medication, so I never regretted quitting it.	M	61	2 weeks		7/16/2008
4	TAB due to borderline Ovarion Tumor	Sides Effects FROM the Premarin? I have gained 20 pounds and find it hard to get off even through diet and exercise. My Cholesterol and BP are up - but this could be the weight gain.	I was miserable about a month after surgery and the GYN/ONC prescribed Premarin and it was great. Going through surgical menopause while recovering from a major surgery was just not an option. I have been tapering off of the Premarin for 6 months now.Sometimes when I would lower the dosage I had minor symptoms My last dosage before quitting was .145 every other day. I have been completely off for two weeks. I have had night sweats, hot flashes and have mostly felt achy and tired. I am determined to be through with this medication- so hopefully things will settle down soon.	F	46	18 months		7/13/2008
3	Pelvic Prolapse	Vaginal dryness to the point where my bladder was not supported and began to prolapse into the vagina. I am post-menopausal and had few symptoms throughout the menopausal process.	After only 3 months using a weekly Premarin vaginal suppository, the health of the vaginal wall is much improved--the bladder is being supported. However, I have had a severe headache for the past 3 weeks, am anxiety-ridden, short-tempered, have leg cramps, and heart palpitations.	F	60	3 months		7/8/2008
4	Perimenopause and PMDD	Tired and fatigued.	Since taking Premarin, I am finding LESS hair in the shower drain. Emotionally, I feel more like my old self. The weepiness is gone and my PMDD symptoms are less.	F	44	3 weeks		7/6/2008
4	TAH & Oopherectomy 2001 @ 35yrs	Hot flushes, tearfulness, forgetfulness, anger, impatience, insomnia, depression.	I have had no menopausal symptoms since taking premarin but I have gained about 7lbs around my middle which won't shift, and I am beginning to get downy facial hair. My main problem is that I have been getting dreadful hemiplegic migraines since taking Premarin. I get one or two a month which is relatively few compared to some mirgaine sufferers but they are severe and I cannot function for about 24 hours afterwards. I dread travelling to other sites with work in case I get a migraine while driving. My Doctor wants me to stop HRT but I am reluctant to go back to the insomnia and depression. I honestly feel that I cannot function without HRT I have been trying Pizotifen & Propranolol along with Sumatriptan but I am still getting the migraines. Going to see Doc tomorrow about changing to an HRT patch. If that doesn't work I will stop taking HRT and see what happens.	F	40	5 years		6/29/2008
3	complete hysterectomy	muscle cramps (mainly in shoulders and legs)	After recently taking myself off premarin, the leg and shoulder cramps are gone. The cramping was not an immediate side effect for me. It took a while. But after the "process of elimination" theory from a couple of prescriptions that I was on Premarin seemed to be the one that was causing the severe cramps.	F	51	4 years		6/19/2008
2	Full Hysterectomy	I began taking Premarin about 2 months ago, .625 and felt no change at all. Dr. increased dosage and still no results, I just picked up a new dosage of 1.25 and am now nervous after reading all your results from use.	My syptoms before the drug were; weight gain, memory loss, loss of energy, syptoms of depression, inability to focus and feelings of being out of control..my doctor tells me that I will feel 100% better with this medication and can expect to lose weight and regain my past life....now i am questioning his comments?	F	41	2 months		6/18/2008 Email
1	Hysterectomy	Horrible horrible side effects - after 2 weeks of starting on Premarin - severe joint pain, very heavy lower body feeling. After using for 2 months, I quit it, and the 3 weeks since, have had no return of hot flashes, or night sweats (yet?).	I ha all of the nasty side effects - makes hot flashes seem easy in comparasin.	F	51	2 months		6/17/2008 Email
4	Both Ovaries Removed	Slight weight gain	My only complaint is slight weight gain. I have to be much more careful on what I eat than ever before. My terrible night sweats and hot flashes throughout the day are almost obsolete. My mood has been terrific. I had severe vaginal dryness but since taking the oral Premarin as well as the vaginal creme - intercourse is enjoyable again without the pain.	F	30	30 days		6/14/2008
1	HRT	headache, high anxiety, suicidal/depressed thinking, crazy thinking, tingling/prickling in head and body, urine problems.		F	38	2 weeks		5/26/2008
1	menopausal symptoms	My mother was prescribed this for 11 years and it GAVE HER BREAST CANCER. If you still have your ovaries and you take this, you run a high rist of breast cancer. If you have had a hysterectomy with ovary removal than you should be ok i think??		F		11 years		4/19/2008
5	hrt (hypogonadism)	only good side effects including weight loss ! (BMI was over 30)	My symptoms before trying it were : night sweats, muscle pain, osteopenia, high calcemia, high T4/TSH, libido decreased. I'm intersex (delayed puberty due to low LH-hCG bioactivity, partial gonadal dysgenesis)		41	12 weeks		4/18/2008 Email
4	total hysterectomy	weight gain right around the middle despite diet and exercise, joint pain, blurred vision	I found this site looking for answers. After reading 50+ negative comments and the 2 or 3 positive ones, I am tossing this drug. I am thrilled to see that I am not the only one with these symptoms! Whoever created this site.. THANK YOU!	F	40	6 years		4/18/2008
4	complete hysterectomy	major weight gain, tire around the middle	I had a complete hysterectomy on ll/15/07, there was a mistake made and I ended up with my ureter cut. So a second surgery was required immediately. I did not have any hormone replacement until about 2.5 weeks after surgery. I went back to my doctor he prescribe climara patch, which would not stay on and caused my skin to burn. So the doctor switched me to premarin .625 and now I have a tire around my middle. I excerise six times a week for one hour since I was release from the doctor's care 1/8/08. I also have good eating habits, I have not lost one pound, instead I have gained. Reading everyone else's comments have given me the tools to make some changes. thanks	F	51	58 days		4/10/2008 Email
5	complete hysterectomy at age 40	None at all! I stopped for awhile when all the scare studies about estrogen came out then asked to go back on them after a couple of years of horrible hot flashes and depression. I feel great with the low dose of this pill.	Take it, it works!	F	56	16 years		3/26/2008 Email
3	TAH CHRONIC TIREDNESS LOW SEXUAL LI	ONLY STARTED TO TAKR PREMARIN YESTERDAY AWAITING ANY POSSIBLE SIDE EFFECTS HOPEFULLY NONE	FEELING QUITE CONCERNED AFTER READING COMMENTS FROM OTHER PREMARIN USERS	F	54	2 days		3/26/2008
4	Had a hysterectomy	hair loss, weight gain, stiff legs and joints,	I was put on Premarin .625 after a hysterectomy, it made me feel bloated, my breasts felt heavy, my stomach swelled, weight gain, my hair grew thin and balding, I was breathless, I came off it after 9 years and it was awful, dreadful sweats, skin dry mind was muddled, suffered this for 2 years, and went back on it but I would rather find a natural alternative to premarin. It does make my skin look younger, though and gives me more energy.	F	65	15 years		3/23/2008
5	complete hysterectomy	No negative side effects	I have had none of the side effects others have mentioned. I feel the benefits far outweigh whatever negative press Premarin may get.	F	58	11 years		3/10/2008
3	Complete hysterectomy	Vaginal dryness and thinning of the skin around the vaginal areas.	I have tried stronger strengths and have stopped taking it because I have felt so bad while taking the Premarin. I am now taking 325 dose. Actually I started searching the web to see what was possibly making me feel so "lifeless" now. I could actually stay on the couch all day long. No interest in anything and there is no other reason not to be interested in things. I'm just tired all the time! I sleep great with the help of melatonin and eat well too.	F	44	7 years		3/9/2008
5	Hot flashes	none	I feel great and look much younger than my years...	F	66	20 years		3/6/2008
3	complete hysterectomy age 16	bloating, swelling of joints, skin discoloration, hair loss, breast tenderness, vaginatis, mood swings,	did not realize how bad this drug made me feel until I quit taking it two years ago	F	46	29 years		2/24/2008
3	Hysterectomy, doctor said I need it	I am not sure if these are side effects from the PRemarin or from the Nitrofur they were giving me--weepiness, depression, anxiety, weird thoughts in my head. Sunday night, I had the adrenaline rush, fogginess and all. That was after my second day of Premarin. Sunday and Monday I was in pain(bladder) and they thought maybe it was a UTI. On the way to get the medicine, I had the adrenaline rush feeling again. That was the third day of Premarin and my synthroid. Monday night took the antibiotic. Tuesday, woke up with leg pain, and all week, the tingling and numbness and all in my legs was there, except Wednesday, until Wednesday night. Thursday, didn't take the Premarin, extreme fatigue and the head stuff started. Was still on the Nitrofur. Friday morning, head stuff was weird. Saturday, the head thing was fierce, felt like creepy crawlies, and extreme fatigue. They have all told me, oh it is just a viral infection attacking your nerves. Went to the ER Saturday, and they did a CT scan, t	Premarin 1.25, Nitrofur was 100 2 times a day, and the Synthroid is 75 mcg. I am really trying to decide about the Premarin and what to ask my doctor when I go back to see her. We are waiting also to see if I have an adrenal gland dysfunction and/or carcinid tumor. I had Ovarian Cancer in 2006 but they got everything and took everything out and have not had to have chemo.	F	38	5 days		2/20/2008 Email
5	Hot Flashes, Sleepless nights	I fell wonderful. I can finally sleep and hot flashes are gone. I have also lost 6 pounds in one month. I have been on premarin .3 for 6 weeks and am very pleased.		F	51	6 days		2/14/2008
4	hrt	Hard to say because I was taking Provera with it as well		F	49	4 years		2/8/2008
5	Had surgery when I was 38 years old	Had no side affects until 8 months ago when my dr took me off it, then my hair started to fall out and my skin became so wrinkled! I have gone back on 1/2 dose, but plan to go back to full dose. I love my hair and the skin I had, want it back! I'm 69 and I'll continue taking 2.25 mg for the rest of my life.	I'll continue to take it. Started taking it when I was about 39 years old. It kept my skin beautiful and my hair didn't fall out until I stopped taking it.	F	69	30 years		1/29/2008 Email
5	total hysterectomy	I coulden't sleep after having my hysterectomy so doctor put me on .625 premeran apex three weeks after surgery. I go off of it on the 25 of the month and start again on the first.	I heard it was not good for you to be on premarin very long so apex 5 mo ago I started splitting mine in half. My hair is falling out my head is sore and have been having more cramps. I am 5.2 and weigh 135.I have not had any complications except my hair. I feel great, play golf and do yoga. I am going back to taking my.625 premeran.	F	77	25 days		1/20/2008
1	Excessive menstrual bleeding	Hunger then lack of hunger within a matter of days, trouble sleeping, feelings of sadness and hopelessnesses, almost depressed, anxiety, my hair started falling out when brushing or washing, general tiredness and feeling not like myself.	My Gyn put me on Premarin after a laparoscopy to treat 4 weeks of menstrual bleeding, his thinking was that it would balance out the hormones to stop the bleeding, was concerned after researching that Premarin can increase the size of uterine fibroids as just discovered that I have many (which may be causing the bleeding) after doing further research, especially into how Premarin is manufactured decided the risks and side effects outweigh the benefits and took myself of the tablets today, hoping my mood will now get back to normal.	F	36	7 days		12/21/2007
1	total abdominal hysterectomy	Allergy type reactions. Weight gain,moodiness. Nervousness,nausea,headaches,swelling...feeling unwell....I could go on and on!	Awful stuff and there are so many better alternatives! This drug should be banned! Not to mention how it is made! WOMEN TAKE CHARGE OF YOUR HRT! ASK FOR SOMETHING ELSE! I STOPPED PREMARIN AFTER 5 YEARS OF A STUPID DOCTOR PUSHING IT ON ME...NOW I AM TAKING ESTRADIOL! MUCH BETTER!	F	35	5 years		12/20/2007 Email
4	Diagnosed with Turner Syndrome	Wen off the Premarin: Emotional, Hot flashes, Dizzyness, Personality disorder, Depression, unable to think clearly or stay focused.	I was diagnosed with Turner Syndrome when I was 12 years old in 2000. I started taking Premarin in 2003 starting at .3MG than to .9MG than back down to .6MG. I havent had any serious side effects except for heart palpitations every once in a while, but when I dont take my medication its worse. I get dizzy, my blood sugar drops immediately, hot flashes, one minute I am happy, the next Im suicidal. I get major mood swings and I become depressed permanently until I go back onto my medication.	F	19	4 years		12/4/2007 Email
2	hystorectomy	had a hystorectomy in 2003 with 1 partial ovarie left, had that removed 10/25/07, now its 11/10 and have had the worst symptoms. Hot flashes constantly, night sweats, fatigue, body aches. my dr put me on.625 premarin a week ago, no change yet almost feel worse, very tired, just icky. How long before i feel relief?		F	39	1 weeks		11/10/2007 Email
4	total hysterectomy	the one symptom that really bothers me is melasma, I had such clear skin before, now i have blotchy skin, if anyone can tell me how to get rid of melasma, please e-mail me.		F	44	4 days		11/9/2007 Email
5	Hysterectomy	For the first few years, I gained weight, but I also ate a lot more. Occasionally, I have had problems urinating, but that goes away when I skip a day on the pill.	I am 65 and have been on the drug for 22 years. My doctor wants me off of it, and I did wean myself down to 3 pills at .6 mg a week. After six months, my skin is crepey and dry. I aged 10 years in those 6 months. Last week, I resumed daily use and feel much better already. I'll probably do five days on and two off at least until I am 70. I can find NO statistical data proving a link between estrogen-only usage and breast cancer. The data is all linked to estrogen-progesterin (which I refused to take 22 years ago after reading how unfavorably the Europeans were to it even back then). I think it's human nature to blame something when we get a disease. Premarin alone may or may not cause breast cancer, but the data just isn't there in my opinion. Quality of life means something here. My breast friend got a vicious form of breast cancer at 68 and she has a complete hysterectomy and NEVER HAD HORMONE THERAPY. So who knows?	F	65	22 years		10/24/2007 Email
1	Hysterectomy and to protect my bone	Thin bone, enlarged my heart, irregular heart rate, joint, muscle pain, serve headaches, sore on my arm that would not heal, anxiety, memory problems, personality changes, panic attack, depression, pre cancer cell had to have laser treatment, masses weight gain, serve breast pain, had a knee replacement. I have an allergy to horses. I also have been told I have Fibromyalgia and I think this drug is the cause.	Started taking this pill when I was 40, it was nothing but hell for me. I was told when I was in junior high school that I reacted to horses and that I should never eat horse meat, or anything that came from horses. When I started taking this drug I did not know it came from horse, I was a farm wife raising 4 kids. When I found out the doctors would not listen to me about the side effect I was having, I was on the drug about 5 years when I found out. I was on the drug for about 12 years. This drug destroyed my life. I walked on a broken foot for almost 3 years because the doctors keep saying I was protect because I was on premarin. I was refused care because of this drug. I fear I will not get medical care in the future because of this drug. The very first pill made me sick, told my Doctor and he called me a lair.	M	57	12 years		10/23/2007
1	Hystorectomy total	my mom experienced the weight gain, momory loss, blurred vision, and the sadness	Started taking after the surgery, for approx. 18 yrs. then found a base ball size lump in her breast wich was malignant, and matatised into her spine, brain! She is now cancer free due to radiation, and tomoxifen. I do not recommend this drug for anyone. If you are still unsure, feel free to look up the case that was just settled in Nevada how 3 women just got awarded $99 million due to taking premarin and prepro!! And some states have taken it off the market!? A few years of hot flashes, and sleepless nights are WELL worth going through ANY cancer treatments. If you have any doubts, LISTEN to your body. DO NOT TAKE THIS DRUG!	F	57	18 years		10/16/2007
1	To open cervical canal	I am fully menopausal, so no hot flashes to deal with. I am inserting Premarin to make my cervical canal more accessible for colposcopy. I have had no hormone replacement therapy.	I believe this medicine is affecting my predisposition for depression. I have had some challenging life circumstances lately, and I am only taking Premarin for six weeks; hopefully I am in my last week. My emotions are very affected, I feel depressed and unable to engage in work or other activities to my utmost. So I hope that this course of treatment works to make my cervix more accessible and I can quit this stuff!	F	51	6 weeks		9/30/2007
3	complete hysterectomy	virtually all side effects listed by others except hair loss	Had full hysterectomy including ovaries in 2003 & took Premarin right away. High blood pressure, weight gain, tired, sadness, chest pains, shortness of breath, constantly hungry, etc. (all of the side effects). Doctor just dosage to 1.25mg from .625 about 2 mths ago. My ankles started swelling 3 wks. ago. These website testimonials explain why. I will start weaning myself & hope for the best. Not looking forward to night sweats & wrinkles. Thanks everyone for sharing your stories in real language.	F	52	4 years		9/13/2007
1	early onset menopause	aches in legs and feet	After using Premarin for 18 months, my Pap smear came back precancerous cells. I was treated for that. Two and a half years later my mamogram showed a small tumor. There is no history of breast cancer in my family. The needle biopsy showed atypical ductal hyperplasia. I followed the required mamogram schedule. Three years later the next needle biopsy showed cancer. When the lumpectomy was run thru the lab it revealed estrogen and progestin in the same proportions as the Premarin. My surgeon asked me if I would consider quitting the hormones and my answer was not just YES, it was HELL YES! I have been hormone free for three years, feel great and my mamorgams show a marked decrease in the usual lumps and bumps. Do I think there was a connection; yes. Would I recommend HRT to anyone--NO WAY.	F	57	7 years		9/8/2007
4	Complete Hysterectomy	None.	I have tried other HRT and Premarin has been the best. I couldn't sleep, I lost my appetite, I had very bad headaches, hot flashes and blurred vision. Since I have been taking Premarin, I can actually sleep, the hot flashes have deminished, and I have more energy. I continue to battle with the blurred vision however.	F	32	1 years		8/7/2007 Email
4	Complete hysterectomy and removal o	Only brittle nails and increase in breast size. I've been taking Premarin 1.25mg since the operation and I did gain 10 lbs which I have kept. For the last three years I started with leg cramps (really bad), charlie horses on my toes, my legs to the point where I wake up (have always been a deep sleeper), also charlie horses on my hips and my back to the point where I could not straighten up. This cleared when I started taking Potassium/Magnesium/Zinc. But now, when I exercise 4-5 days a week I feel achie all over. A low-feeling ache al over that will not go away.	My Dr. feels I've used Premarin 1.25mg for too long and is afraid of heart problems. I feel great with this as I do not have any of the side-effects associated with this, no mood swings, no headaches, no night sweats, or vaginal dryness, no hot flashes. The only thing was an increase in memory & libido. I've never smoked, seldom drink socially, keep stomach down with exercise. I exercise 5-6 days a week. Bad cholesterol is slightly high but high in the good cholesterol. I've always looked 10-15 years younger (good genes) and I still do. Skin is not dry and still has collagen. I do drink a lot of water all day and always have, I just like it. I had a lot of tests done for the leg cramps/charlie horses, these showed high bone density, electrolytes were OK, nothing was found. I am taking Potassium with magnesium and zinc and the problem with the charlie horses seemed to go away. I do have arthritis over the thumb on both hands and on the shoulder bone but besides that I'm O	F	63	18 years		8/2/2007
5	hormone defiencincy	it is wonderful		F	51	15 years		7/30/2007
1	Total Hysterectomy	Abundant hair loss, dizzyness, temporary hearing loss in one ear, major short term memory loss, legs cramps, aches & body joint pain, nasty rash all over my body (originally thought it was poision ivy), weigh gain of 20+ pounds within one year, bloated feeling.	Went on this drug immediately after surgery. Side effects were affecting my job. Couldn't even think straight. My long hair was falling out in handfuls. Gained 20 pounds. Quit cold turkey, now its been 2 weeks, no nasty withdrawal symptoms and feeling so much better and can remember what I did yesterday. No more HRT for me.	F	54	1.5 years		7/28/2007 Email
1	total hysterectomy	50 lb weight gain in 2 years, panic attacks, depression, lower back pain, dizziness, headaches, nausea, rash, nightmares, dry skin, blurred vision, memory loss.	For those of you who have chronic fatigue syndrome like myself be careful it will only make things worse. I have tried 5 different HRT'S nothing works. I take 1.25 mg it's helps me to sleep thats why I take it.	F	51	2 years		7/22/2007
3	Hysterectomy	Weight gain (30 kg over the years no matter what I did), bloating, belly, spare tire, leg swelling, ankle /joint pain, cramping, vaginal dryness, lack of libido.	To be honest, Premarin saved my life in the beginning. The doctor didn't prescribe HRT when I had my hysterectomy and was just in my late 30s. By mid 40s I was sobbing all the time, depressed to put it mildly and totally miserable with hot flashes leaving me soaked and dripping (very embarassing). The firt few years Premarin saved my life. However as the years went on began a gradual weight gain, developed high blood pressure, extreme water retention, large belly and thinning hair. I have been off Premarin for 10 days due to the fact that I can't get it. (It has been taken off the market where I live, so imposed cold turkey big time!) I have gone on to Phytoestrogen and so far am amazed at how good I feel. My middle is shrinking on its own, I realized my ankles aren't swelling and my legs aren't hurting so badly. I am having headaches, but hopefully that will pass. Now anxious to check my blood pressure. I am hoping that will go down. All in all I feel pretty good.	F	57	10 years		7/21/2007

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Key to ratings: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine.

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