SPIRONOLACTONE Reviews (SPIRONOLACTONE)

Average Rating: 2.4 (268 Ratings)

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 DIURETICS ALDOSTERONE RECEPTOR ANTAGONISTS

 Type: Rx Drug

  

SPIRONOLACTONE  (SPIRONOLACTONE):  Spironolactone is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems. This medication is also used to treat low potassium levels and conditions in which the body is making too much of a natural chemical (aldosterone). Spironolactone is known as a "water pill" (potassium-sparing diuretic).   FDA Approval Date: 1999-07-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SPIRONOLACTONE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SPIRONOLACTONECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Transgender HRT Regimen Initially, prior to system stabilization and acclimitization, severe leg cramping. This eventually ceased. The drug is being taken for its androgen suppression side effect and it is effective for this purpose. Current dose is 400mg/day. F 8 months
4/24/2006
 1  Acne WHEN WILL MY BODY GO BACK TO NORMAL. I TOOK THIS DRUG FOR THREE WEEKS AND HAVE SAGGING FACIAL SKIN LOSS OF COLLAGEN NO SEX DRIVE AND PAINFUL BREASTS. BEEN OFF FOR 2 MONTHS NO CHANGE. 1 days
7/17/2015
 1  Facial hair Hair shedding, severe abdomen cramping, breast enlargement. I have gain about 20 pounds in my mid abdomen area. I am very dissatisfied!!!!!! I did not see any changes in facial hair. F 3 months
25mg 1X day
10/25/2016
 1  Edema lower legs This should be taken off the market!! Within days my legs felt like my lead and started cramping up so bad I could barely walk. Upset stomach and overall unsteadiness and awful feeling. I tolerate medication well but this by far was the worst. I found other ways to reduce the Adema with some exercises and lymphatic massages which helped wonderfully Please be very careful with this med. I had this reaction by only taking half of a 25 mg pill daily which amounted to 12.5 mg I can only imagine if I took the whole thing what a nightmare that would have been F 5 days
12.5mg 1X day
7/12/2022
 1  Hormonal Acne Depression Do not take this pill. it left me severely depressed and feeling hopeless. F 14 12 months
100 MG 1X day
3/2/2022
 4  Acne I been having VERY irregular periods... it really freaks me out to have twice a month or none at all. I have gotten off of this and my acne came back even worse so I got back on it again. My acne is almost all the way gone now just a little small one here and there. F 16 8 months
100 mg
12/31/2012
Email
 4  Hormonal Acne I started Spironolactone about two years ago, and it took somewhere between 4-6 months for me to really see a difference. But now my skin is as clear as it has ever been. I occasionally get one pimple here and there but overall, very satisfied. Unfortunately, this medicine has completely destroyed my menstrual cycle and caused months without a period, then three in one month. I already had an irregular cycle before starting spiro but it definitely made it worse. F 17 2 years
75 1X day
12/10/2020
 1  Hormonal Acne I was taking spirio for my hormonal acne. I have never dealt with depression because I am usually a happy person but I was feeling so depressed ed I didn't want to go out side I didn't want to eat and I would have extreme anxiety attacks I was scared to go to sleep because thats when my anxiety attacks would come the most. I have dealt with anxiety but never like that. I also had very disturbing thoughts that were uncomfortable. I saw that someone was also having that problem while taking spiro. I felt so horrible when I was taking this I was a mess, and I did not feel like myself. I did I not have these symptoms immediately, they started to kick in about 2 weeks later after starting the medication. But when I stopped taking it, it took about 2-3 days for it to get out of my system but I was feeling much better! It's been 1 week and I haven't have anxiety attack or any of my other symptoms. Just drink a lot of water to wash it out of your body. I understand that not everyone has symptoms but if you are having any of these please STOP taking this medication. Also I would like to add that I did not see any results for my acne it was still that same F 17 28 days
50MG 1X day
3/31/2022
 4  PCOS Hair Loss, slight bloating Period spotting. especially cold in my extremities in winter. slight weight loss, clear skin. unsure about hair growth at the moment but hoping that it will grow. F 18 3 months
50mg 1X day
7/3/2014
 2  high testosterone, acne, extra hair Debilitating anxiety, frequent urination, increased thirst, heart palpitations (at first), and occasional leg cramping. The idea of less male pattern hair growth and less acne sounded wonderful. My doctor failed to warn me about the horrible side effects though. I tend to be very outgoing and since increasing my dose from 50MG to 100MG in the morning and 50MG at night I have had the worst social anxiety. I throw up, shake, and have trouble breathing due to the panic attacks. I have seen very little if any improvement with my hirsutism after taking this pill for a year and a half. Acne has cleared up a bit but I am not sure if that is due to a topical cream I was prescribed for it. My testosterone levels have came down a little bit but not as much as I had hoped they would. Overall, the side effects do not outweigh the positives of this medication. F 18 1 years
100/50MG 2X day
8/30/2020
 1  hormonal acne I would feel extreme anxiety that caused me to throw up regularly (i'm talking minimum 3x a week) and I couldn't eat or sleep for months. I felt like I was genuinely dying from an unknown disease and I couldn't enjoy my entire summer because of how sick I got! If I was in a situation where I would feel even a little bit of anxiety I would throw up. It usually hit me hard at nighttime or early in the morning. I do not recommend this drug unless you THOROUGHLY research it beforehand. I still to this day have bad anxiety whenever I have stomach pains or nausea and the medication had ruined me for months of my life. I was miserable and cannot see myself ever taking it again. F 18 4 months
50-100 MG 1X day
2/24/2021
Email
 1  acne extreme weight gain, 25 lbs in three months (I'm 5'2") it cleared my skin but despite never having a weight problem I blew up like a balloon all over. Doctor and pharmacist are saying it can't make you gain weight. But after seeing post after post from women who had significant and sudden weight gain after starting Spiro there has to be a connection. Be careful --not the super safe med it's made out to be. F 18 3 months
100mg 1X day
11/19/2019
 3  acne my hormonal acne cleared up (cheeks/jaw) but acne on forehead got worse due to anxiety/stress/depression-- which i think was because of the spiro--it made me very moody. Ruined my period cycle-- i was bleeding for almost 3 months straight and then having only spotting everyweek also hair on head got much thinner-- personally dont think side affects are worth it but its different for everyone i guess its worth a try and really did clear up my hormonal acne, but i stopped taking it yesterday and am going to try some new methods that keep my period cycle normal because that really affects your emotional state-- maybe birth control, vitex, or just vitamins from now on gotta remember not to give up or let acne/other cosmetic issues dictate your life--outlook on life is everything and i realized the less i focus on trying to cure the acne the more i enjoy my life doing the things i like and then acne gets better with this positivity anyway-- its like what they say about chasing happiness! F 19 1 months
100
9/9/2015
 3  Acne Irregular/missed periods, urinating frequently, stomach cramps This hasn't really helped my acne yet but I haven't taken it that long yet F 19 2 months
50 2X day
4/20/2012
 1  Acne So i have been prescribed spironolactone for about 8 months now, when I first started it I had been taking it for about 2 weeks, after the second week I noticed very bad panic attacks and anxiety so I stopped it immediately. I went to my dermatologist about a month later and he asked me how it was going. I told him I stopped taking it because i was having really bad panic attacks and anxiety. He basically told me I was wrong and the spironolactone would never cause or has any history of panic attacks or anxiety. So just recently I figured I'd try to take it again. I've been on it for about 2 weeks now and the insane anxiety and panic attacks are back and way worse. It's has caused me to feel like I'm going insane and not myself at all to the point where I feel like I need a therapist and counseling. I am not taking any other medications so my conclusion is that this is the reason for my terrible side effects. After reading these other reviews I feel so much better knowing my dermatologists made me feel stupid and that I was right all along. F 19 15 days
20 mg 1X day
10/19/2022
Email
 1  Acne Panic attacks, anxiety, intrusive thoughts. & depression This is the absolute worst medication I have ever been on. Yes, it cleared up my acne but I would rather have just dealt with it to avoid the mental heath issues I have now. When I started this medication, I was going through a rough patch in my life which is why I felt that all of these problems started happening. However after finding this page and looking at all the comments I know for a fact that it's from this medication. The first bad experience that happened while on this medication was right after I took an edible. I smoke marijuana weekly so I assumed I'd be fine. After taking it, I started thinking about every bad thing I had ever done and my heart started racing. Someone else in the comments said their bf almost had to take them to the hospital and I swear that's what happened to me. I thought I honestly was going to have a heart attack. After that I stopped smoking Bc I figured that's what caused me to feel like that. But for the next couple of months I started experiencing severe anxiety before work. My heart would beat so fast and I felt uneasy. I also started getting intrusive thoughts which caused me to have to go therapy because I didn't know who I was anymore. I felt crazy and not like myself. I've been off this medication for three months now and finally in the last few weeks I feel I have been doing better but I'm still no F 19 4 months
50 3X day
1/9/2023
 5  Hidradenitis suppurativa CURED HS!! Dry Mouth & spotting a few days before period starts. Completely cleared my HS. I had mild/moderate cysts with occasional drainage, a small amount of pitting (2 areas), but no more than 3 cysts at a time. I also used to get an occasional cyst around genital area (usually ended up pitting there). I had extreme pain and swelling under my arms with itching prior to starting spiro. I started out at 50 mg a day for 3 months. The dose helped reduce pain, but did not clear my armpit cysts completely. I lost 10lbs. After taking the 50mg for 3 months, my dermatologist upped me to 100mg. The first month I still got one cyst on my armpits here and there, but since then I have been cyst-free for almost 2 months now! My weight has remained the same (150lb, I'm 5'5, athletic build), but since taking the 100mg dose my face is much less puffy!. It took about a month on the 100mg dose to completely clear my armpits. I still experience discomfort and some itchiness under my arms, but my skin doing great. I also used to get occasional cystic acne on my back, which has gone away completely since starting spiro. The side effects can be tough, especially the first few months, but now I barely experience anything (besides dry mouth). I feel like I have more energy and confidence since starting this medication. The side effects ARE a little strong, but it has reduced the extreme pain from my HS and increased my quality of life ten fold. F 20 6 months
100MG
5/12/2020
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 3  acne and oily skin Dry mouth,increased urination but less oily skin. Still no improvement in acne F 20 1 months
50mg
12/6/2012
Email
 1  Acne Anxiety, depression, panic attacks I suffer from severe anxiety and panic attacks and am on my mental health journey just as I am on my acne journey! This medication may help one but will completely ruin the other! I feel hopeless and worthless and like I don't want to leave my bed because I can't stop crying day 3 now. Then when you finally feel a little better the feelings creeps back up! I would way rather have acne for the rest of my life than be on this devil pill! Please reconsider taking this if you suffer the way I do! F 20 4 days
30 1X day
1/19/2021
Email
 1  Acne I started using spironolactone back in the summer time and after just a few weeks of using it i was uncontrollably sobbing at my job which then resulted in me putting in my 2 weeks and getting terminated early. I honestly thought it was just the stress of moving somewhere new and losing my friend so I didn't think too much into it. I slowly started to feel irritable towards everything i was making many improvements in my life but nothing ever made me happy. During November is when it all really started to go down hill I started failing almost all of my college classes and not caring because why should i? I was snapping at my roommates over the dumbest things and would hole myself up in my room for days and would talk to nobody. I had no idea what was wrong with me I didn't enjoy anything anymore and this was so unlike me. I have never been one to need therapy but in that time I knew I needed to go because something was seriously wrong. I was a pretty heavy smoker when it came to marijuana and had taken an edible one night and FREAKED out my heart rate had bumped from 75 to 150 in about 5 minutes and i almost had to ask my boyfriend to take me to the ER because I felt i was about to die. Looking back on this I knew it was the medication because I have never reacted like this to marijuana before. After that moment it just seemed to make it much worse I was thinking insane thoughts about death and every other possible thing that could spike my anxiety and I could feel anxiety attacks coming on frequently. I would randomly get shaking and dizzy and feel like i needed to throw up nothing was making me feel better. Yesterday is when i decided to look up side effects of Spironolactone and nothing I read said anything of the sort until I stumbled upon this website. I am so grateful that other women have shared their experiences because I knew I wasn't crazy. Please don't take this medicine if you can help it. it has cleared up my acne but the mental health issues it brings is simply not worth it. I will continue to warn as many people as i can about this. F 20 6 days
100 mg 1X day
1/6/2023
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SPIRONOLACTONE  (SPIRONOLACTONE):  Spironolactone is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems. This medication is also used to treat low potassium levels and conditions in which the body is making too much of a natural chemical (aldosterone). Spironolactone is known as a "water pill" (potassium-sparing diuretic).   FDA Approval Date: 1999-07-29 (Sources: U.S. Centers for Medicare Services, FDA)

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