SAVELLA Reviews (MILNACIPRAN HYDROCHLORIDE)

Average Rating: 3.0 (158 Ratings)

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SAVELLA  (MILNACIPRAN HYDROCHLORIDE):  Milnacipran is used to treat pain caused by a condition called fibromyalgia that affects the muscles, tendons, ligaments, and supporting tissues. This medication is a serotonin-norepinephrine reuptake inhibitor (SNRI) that works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).   FDA Approval Date: 2009-01-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction highest to lowest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR SAVELLACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Fibromyalgia I was on Savella over 5 years ago and had to stop taking it because I was put on Effexor and you can't take Savella and Effexor together. My Fibromyalgia used to only effect me over cold months now it is effecting me 24-7 all 12 months. I'm no longer on Effexor and now just started back on Savella. I live in North Carolina and we get hot days. Heat works great for my Fibromyalgia and usually take 3 hot showers a day when my Fibromyalgia is flared up. Now that I am back on Savella it has almost taken all the inner burning away and the ide spread chronic pain I was feeling like I've been in a physical fight. The only thing that is bothering me with this med this time is I feel like I took a sleeping pill. I just want to sleep. I think I am going to cut back to just taking Two by mouth of 50mg one time a day instead of two by mouth twice a day. I feel this may be a bit much just starting back on it again and need to gradually work up to the higher dose. I also have a little nauseated feeling that I can tolerate since I now know longer feel like I've been physically beat up since back on Savella. I also have arthritis spreading throughout my body so that and Fibromyalgia is not a good mixture. To sum all this up I am happy to be back on Sevella and 95% pain free however the side effect of this making me just want to sleep I am going to have to reduce my intake and see if that reduces the just want to sleep I am encountering. To those out there who suffer with the invisible disease called Fibromyalgia my sympathy is with all of you. I know how this disease can effect your concentration, lack of ability to move or lift, chronic wide spread pain and no energy. You just have to try different things to see what work best to relieve pain. My good days is when I have motivation to get things done my bad days I lay around and do nothing except take several hot showers that work for me to ease the chronic pain. I keep my central air on 75 with a ceiling fan. Cold effects my Fibromyalgia bad and brings on the chronic pain. I actually have to wear a jacket in the Spring/Summer time in a grocery store ect because of how cold they keep the store. Stay strong and don't let Fibromyalgia get the best of you. Don't be hard on yourselves if you have days that you can't seem to accomplish anything. Role with the good days and let the bad days run it's course. F 53 2 days
Two 50mg 2X day
5/25/2021
 5  Fibromyalgia In the beginning I felt that high feeling and was moody. I still have hot flushes off and on. I've lost weight too as it has taken my appetite away. Especially during the day. My extreme foot pain that was terrible is gone and other pains are alleviated!! F 40 2 months
50 mg 2xd 2X day
8/14/2020
 5  For fibromyalgia pain In the beginning dealt with a lot of nausea, and pain until the dose was increased to 100 mg twice a day. The nausea was on as ling as I took the Savella with food - a carb. Savella saved my life! I am a mother of three, and I was in a lot of pain and slowing down more and more. Savella let me have my life back and the ability to be a mother to my children. I am so very grateful! F 47 5 years
100 MG
1/23/2015
Email
 5  Fibromyalgia In the beginning, nausea, sweating, it took a month or so to really help with pain. The side effects were so bad, I almost quit taking it. But, I am glad I stuck it out. The side effects went away and so did most of my pain. Savella has really helped me function and enjoy moving everyday. F 50 3 years
200mg
6/3/2014
 5  Fibromyalgia No side effects at this point. I've been on the highest recommended dose (100mg twice per day) for about 2 months. Prior to that, I started with the tiration pack, and took that for 2 weeks. Then, my dr. increased my dosage slowly, to 50 mg. twice per day. I took that dosage for about a month, and I didn't notice any decrease in my pain. My dr. explained that it usually takes about 2 months (on the highest dose that will work for you) to start feeling relief in pain. I tried to be patient. Now, after being on a total of 200 mg. per day, my fibro. pain has greatly diminished. I still have pain, but it's gone from a level 10 (horrible, horrible pain...can't function) to a level of 2 (still have numbing, aching pain, but I can live with it). My pain was where it was greatly effecting my quality of life, and I literally didn't want or feel like doing much of anything. I was on Lyrica for about five months, and Lyrica worked at first, but after four months, it completely stopped working for me. Savella has been a lifesaver for me. For those of you who cannot afford the Savella, please go to the Savella manufacturers website and go to the Patient Assistance area. You can get Savella for free, if your income qualifies. Please don't go without it, if it is helping you. F 54 2 months
100 mg 2X day
8/25/2013
Email
 5  FMS, CFLIDS Began with clinical trials, so I have been on this medication a bit longer than those who started after FDA approval. It has changed my.tolerance of FM symptoms Significantły. If you are oink this medication and your insurance will not cover it, or no ins. Coverage at all contact Forest Pharmaceuticals in St. Louis, MO and talk with them about you're positive experiences with Savella and request their Patient Assistance Program. Some paperwork, easy, straight forward. Once approved the work I 90 Day increments and mail the meds to you prescribing doc where you will pick it up. A short tel call after that all required to continue, ard a new written Rx from the doctor. Please use the PAPS the pharmacy companies have just for this purpose. Please do not just stop taking something that is doing wonders for you. F 46 5 years
50 2X day
12/21/2012
Email
 5  Chronic disabling pain Constipation, insomnia F 44 1 months
25mgs 2x
11/27/2012
 5  fibromalgia None F 49 2 years
100 MG
7/18/2012
Email
 5  Fibromyalgia and + ANA Insomnia and felt like I couldn't lie still but that went away after about 3 weeks. I've been having problems since 14 so the insomnia was nothing new since I haven't slept thru a night in years because of my nawing joint pain and discomfort. I feel great after being in this for almost 3 months. I still have my days but that's a lot better than everyday being miserable. F 24 3 months
50mg 2xD
7/13/2012
 5  Fibromyalgia some dizziness and slight weight loss in the first month, but have maintained a constant weight since. I've been extremely happy with Savella. I was first on cymbalta, which was ok, so I thought, then my Dr switched me to Savella, huge pain relief! I had a brief experience after about a year of taking it where my Dr switched me back to cymbalta, and the pain was unbearable! Within weeks of switching again to savella I was again pain free (minus the occasional flare-up). I've been on it a little over 3 years and am now able to again play tennis, volleyball, etc. and live my life without the pain and exhaustion :) F 29 3 years
50mg 2X day
7/13/2012
 5  Fibro Fortunately NONE Having my first flare up since starting Savella. I'm scared to increase the dose because it may not work. Going back to the doctor tomorrow for help, none of the opioids worked this was the only drug that gave me any relief. F 48 4 months
50 mg 2X day
6/12/2012
 5  Chronic joint and muscle pain I started with 15 mg a day for a week and they 15 2X a day for a week 25 and 15 a day for a week. 25 and 25...25 50...50 and 50 a day. My dr had me start very slow because of the side effects and it helped. I would get nausea about 90 minutes to 2 hours after I took the pill and my heart raced and I could not sleep at all. I also noticed I was short of breath and if I did anything that took effort (mowing the yard) I could not catch my breath. It would take about 4 to 5 days for my body to get use to it and then it was time to does up again. I also lost about 5 pounds and my body felt flushed. After two months of the pill the my side effects are gone except the shortness of breath and I don’t require as much sleep as I did before. I do notice if I don’t eat at regular intervals I get nausea but if I eat it goes away. It took my pain away!!!!! I have been dealing with pain since I was a teenager and the last few years it has taken away my life. This medicine has been amazing even with the crapy side effects. It was scary as hell that first month with my heart racing and being short of breath ( I even went to the hospital one night because of chest pains) but it was worth it. What is one month of hell compared to a life that is pain free. I have more energy, I am happy, I am motivated to live again. I fixed my garage door after I replaced a leaky faucet all on the same day!!! I feel amazing. I am hoping with time the short of breath goes away. But even still, I am very satisfied F 32 2 months
50 2X day
5/29/2012
Email
 5  CFS I'm the 62 year old male who recently posted about Savella. It did wonders for my cfs but adversely affected my heart. To update: The cfs problems returned within 2 days of ending Savella. Now I'm on Norco 5mg, twice a day, one in morning and one in the afternoon. It does a good job of knocking out the pain and fatigue. I know people go nuts when you mention using an opiate because of the addiction potential. They need to back down. I intend to stay on the Norco as long as my m.d. allows. M 62 6 weeks
50mg 2X day
5/11/2012
Email
 5  CFS Savella did wonders for my CFS. It knocked out 90% of my fatigue problems. But I had to get off it. It substantially increased my heart rate. The blood pressure went up, too. My cardiologist wanted me off it. I'm on a pacemaker so I have a danger of other heart problems so there's no need to aggravate my heart. I'm hoping against hope that the CFS doesn't return. Savella is a good drug for CFS. I, unfortunately, had a side effect that wasn't tolerable. M 62 6 weeks
50mg 2X day
5/9/2012
Email
 5  Chronic severe pain None. It relieved the constant unrelenting pain in my hands I had been experiencing for 6 years during the 1st wk of titration. Now pain in shoulders is bearable. F 52 3 months
100mg 2x/d
3/17/2012
Email
 5  fibromyalgia The first several weeks were tough with nausea and strange craving. For weeks I could only eat goldfish crackers. But after about 8 weeks that disappeared. Now the only real side effect is weight loss,but I'm not complaining about that. F 35 4 months
50 mg x 2
12/27/2011
 5  Fibro/Chronic Fatigue Side effects were mild nausea in first few weeks which has now gone. Worst was the strong heart beats or palpitations at night time. I have reduced dosage to 25mg 2 times daily and they have almost completely gone away. I love this medicine!!! I feel better now that I have in past 8 years. More energy, less brain fog, more endurance, less pain and stiffness. I am waking up at 7am and actually staying awake without having to take provigil. I actually did yard work and painting yesterday and the day before went on a long walk with my son and the dogs! Wow - never thought I would be able to do that again! This has been a miracle for me and I feel like I will be able to go back to work now and take care of my kids instead of being a lump just surviving!! F 52 4 weeks
50 2X day
11/17/2011
Email
 5  Fibromyalgia None that I am aware of except possibly sweating a bit more. Savella is my miracle drug. Before Savella I had tried EVERYTHING from gabapentin (very minimal relief,) to Lyrica (make me feel like I was on illegal drugs,) and Cymbalta (1 pill, made me feel so crazy I called a friend to "babysit" me and my kids until my husband got home) and everything in between. Savella enables me to live a much more active and "normal" life, I am no longer a slave to FMS or to painkllers. Sadly at 130.00 a month I cannot afford it without insurance and after 9 months of taking half a dose to stretch it out (since insurance went away) I am weaning off it. The weaning is bad and my FMS symptoms are through the roof...I even took a full pill tonight just so I can be mobile to bake my sons birthday cake and not be so foggy headed tomorrow. I am hoping a low-cost clinic will help me...soon, because I cannot live like this. Honestly Savella gave me my life back and now finances preventing me from getting Savella are taking my life away again :( One warning is to check drug interactions CAREFULLY, I can't even take cold medicine and I was taking tramadol (Ultram) at first and ended up with seratonin syndrome and nearly passed out at my kids' birthday party in 2009. Luckily I made the connection, went to drugs dot com for the interaction checker and realized what was wrong and called my doctor right away. My poor doctor felt horrible, but the drug was so new (on the marker a few months) when I began taking it that there was very little in F 32 27 months
50 mg 2X day
8/18/2011
Email
 5  Fibromyalgia Sweating but it is subsiding. After just one day, I slept like I never slept before! My side hip pain stopped & more energy. I could turn in bed without waking up but I slept through the night. I just sweat but that is OK. 50% less pain and pain is a 3 and not an 8! Was on Cymbolta but didn't work and side effects. Was on Doxepin and 10 lbs. heavier. At 50 mg. I have some nausea but I just started the dosing pack and doctor said to continue till I get used to medication. Worth a try. Have had fibromyalgia for 23 years and this is the only thing that helps the pain! F 54 11 days
50 2X day
7/11/2011
Email
 5  Fibro,MFPS,Raynauds,RPS,CI,& more Some vivid dreams, but many side effects people think they have from Savella can many times be traced to other things. I could say I had hot flashes, but I was 52-53 at that time. That's called menopause. Many sides effects I could have attributed to the Savella were in reality caused by other things. I went off all my meds(oxycontin, etc.) in 2008 to go on the study for Savella. Unfortunately I got the placebo. I literally almost died. My BP shot up to 210/120 for 8 months. I was totally bedridden the whole time. I went on Lyrica and gained 50 lbs. in 5 weeks, plus it did nothing for the pain. Then my kidneys shut down. Finally by June of 2009 Savella went on the market. I could feel a difference in 1-2 weeks. I went on the highest dose fairly quick because my pain is so severe and causing other health problems. Just remember it is not a pain pill. It will not get rid of ALL the pain. It will not work for everyone. Nothing man does will get rid of this illness. You will have to listen to your body to help manage your pain and other symptoms. And most of all, if you have fibro, as I have for 25 yrs., realize that everything you do will have a consequence to your health. Fight the urge to be overly focused on the pain. I have been on just about every drug and holistic pill there is. Savella hasn't gotten rid of all my pain, but it has worked the best for me. You HAVE to give it more that 1 day or week to see a difference. F 55 2 years
100 mg 2X day
5/31/2011
Email
  

SAVELLA  (MILNACIPRAN HYDROCHLORIDE):  Milnacipran is used to treat pain caused by a condition called fibromyalgia that affects the muscles, tendons, ligaments, and supporting tissues. This medication is a serotonin-norepinephrine reuptake inhibitor (SNRI) that works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).   FDA Approval Date: 2009-01-14 (Sources: U.S. Centers for Medicare Services, FDA)

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