SAVELLA Reviews (MILNACIPRAN HYDROCHLORIDE)

Average Rating: 3.0 (158 Ratings)

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 Type: Rx Drug

  

SAVELLA  (MILNACIPRAN HYDROCHLORIDE):  Milnacipran is used to treat pain caused by a condition called fibromyalgia that affects the muscles, tendons, ligaments, and supporting tissues. This medication is a serotonin-norepinephrine reuptake inhibitor (SNRI) that works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).   FDA Approval Date: 2009-01-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR SAVELLACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Fibromyalgia After titration period no side effects. Seemed to help with energy a few days then it no longer helped. Dr put me on 100 mg tablets twice a day instead of 50. Still hasn't helped and no pain relief the whole time. Now to come off of it! Had fibro for 30 years. No drug approved for fibro has helped. Only tramadol for pain was great. They no longer want to be humane and give pain meds when needed. F 55 0 years
100 mg 2X day
8/1/2023
 1  Fibromyalgia After titration period no side effects. Seemed to help with energy a few days then it no longer helped. Dr put me on 100 mg tablets twice a day instead of 50. Still hasn't helped and no pain relief the whole time. Now to come off of it! Had fibro for 30 years. No drug approved for fibro has helped. Only tramadol for pain was great. They no longer want to be humane and give pain meds when needed. F 55 1 years
100 mg 2X day
8/1/2023
 1  fibromyalgia tachacardia severe, chronic diarrhea, . headache every day with flushing and hot flashes,breathlessness constantly during slightest exertion..scalp itching and loss and thining of hair by handfuls. paired with brilinta (60 mg. twice a day) the breathlessness was unbearable..not worth the side effects for me...not one drug I have taken has helped with 30 years of fibromyalgia F 80 21 days
50 mg 2X day
6/16/2021
 5  Fibromyalgia I was on Savella over 5 years ago and had to stop taking it because I was put on Effexor and you can't take Savella and Effexor together. My Fibromyalgia used to only effect me over cold months now it is effecting me 24-7 all 12 months. I'm no longer on Effexor and now just started back on Savella. I live in North Carolina and we get hot days. Heat works great for my Fibromyalgia and usually take 3 hot showers a day when my Fibromyalgia is flared up. Now that I am back on Savella it has almost taken all the inner burning away and the ide spread chronic pain I was feeling like I've been in a physical fight. The only thing that is bothering me with this med this time is I feel like I took a sleeping pill. I just want to sleep. I think I am going to cut back to just taking Two by mouth of 50mg one time a day instead of two by mouth twice a day. I feel this may be a bit much just starting back on it again and need to gradually work up to the higher dose. I also have a little nauseated feeling that I can tolerate since I now know longer feel like I've been physically beat up since back on Savella. I also have arthritis spreading throughout my body so that and Fibromyalgia is not a good mixture. To sum all this up I am happy to be back on Sevella and 95% pain free however the side effect of this making me just want to sleep I am going to have to reduce my intake and see if that reduces the just want to sleep I am encountering. To those out there who suffer with the invisible disease called Fibromyalgia my sympathy is with all of you. I know how this disease can effect your concentration, lack of ability to move or lift, chronic wide spread pain and no energy. You just have to try different things to see what work best to relieve pain. My good days is when I have motivation to get things done my bad days I lay around and do nothing except take several hot showers that work for me to ease the chronic pain. I keep my central air on 75 with a ceiling fan. Cold effects my Fibromyalgia bad and brings on the chronic pain. I actually have to wear a jacket in the Spring/Summer time in a grocery store ect because of how cold they keep the store. Stay strong and don't let Fibromyalgia get the best of you. Don't be hard on yourselves if you have days that you can't seem to accomplish anything. Role with the good days and let the bad days run it's course. F 53 2 days
Two 50mg 2X day
5/25/2021
 3  Fibromyalgia Nausea. Extreme heat flashes. F 55 45 days
25 mg at b 1X day
8/16/2020
 5  Fibromyalgia In the beginning I felt that high feeling and was moody. I still have hot flushes off and on. I've lost weight too as it has taken my appetite away. Especially during the day. My extreme foot pain that was terrible is gone and other pains are alleviated!! F 40 2 months
50 mg 2xd 2X day
8/14/2020
 3  For fibromyalgia Severe hot flashes and cold sweats . Also made my stomach very sick . Im trying to wean myself off ..right now. F 56 0 months
50mg 2 dai 2X day
7/10/2020
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 1  Fibromyalgia Tachycardia, pounding heart, high blood pressure, several trips to ER due to racing heart. Went to cardiologist, decided to taper off medication, getting Echocardiogram in 2 weeks to see if I have permanent heart damage, caused high calcium levels and high d-dimer level. Never again..I want to live.. F 48 8 months
50mg
6/17/2020
 1  Fibro Profound and incapacitating memory loss that occurred gradually over time. Got so bad I could not remember how to run my coffee maker. MD thought I had Lewy bodies but mercifully the MRI was fine. Dangerous medication with memory issues during the drug trials but somehow still got through the FDA. F 61 2 years
6/4/2020
 1  Fibromyalgia Vivid dreams, confusion, and suicide thoughts F 47 2 days
12.5
2/19/2020
Email
 4   0 days
8/26/2018
 2  Fibromyalgia Hair loss/thinning Helped mental state somewhat, but has not helped at all with pain, especially wide spread nerve pain. F 71 3 months
50MG
7/16/2017
 1  Chronic Pain Hot flashes, sweating, terrible urinary problems (felt like I had a constant kidney infection at 100 mg) lessened when dose decreased but still caused irritation and frequent urination. Horrific withdrawal I thought I had found the answer the first couple months and had my life back. My pain was 90% gone. I could deal with the sweating and hot flashes but the urinary problems were too much, I was in the bathroom at work every five minutes. Stopping this drug was the worst nightmare I've ever had, and I've tried lots of meds. Took six months to get off and still don't feel normal and have strange brain zaps sometimes. F 34 1 years
100
2/28/2017
Email
 1  Fibromyalgia management Blurry vision, dilated eyes, headaches, dizziness, nausea I was taking 50mg twice a day but reduced to just once a day in hopes side effects would reduce. They have not. I have no reduced to 25mg once a day and I am having withdrawal episodes from lowering my dose. F 21 7 weeks
50
11/25/2016
 1   Help with stiffness.but the pain got worse and I started to get shortness of breath weakness my left arm and the left side of my back hurts me so much had to stop it but the weakness and shortness of breath is still bothering me!!!!! M 38 1 days
200mg
8/12/2016
Email
 4  Fibro @ 50mg 1x a day it would seem to quit working mid day. Doctor now has me on 50mg 2x day. It has been a life savor. One issue since increasing the dose is my head itches bad. But I guess that is better than the constant pain. F 56 6 months
50 2X day
8/9/2016
 3  Fibromyalgia My first 2 weeks on Savella went very well. My pain was significantly reduced. I hoped that it would help with the fatigue, which makes some days impossible to get through. It didn't help. At the start of week 3 I developed a very bad headache, blurred vision, pound heart, pressure in my ears and my emotions were up and down. Feeling depressed, anxiety, sad and sometimes just a blank feeling, which is the worst. On week 4 now and reduced my dosage in half. I will be talking with my RHEUMOLOGIST tomorrow. I really pushed my doctor to give me this medication. I was on cymbalta for several years, it didn't do much for my pain but did help with depression and anxiety. I hope it's working for others but without all these side effects. God luck and God Bless F 47 5 days
50
7/19/2016
Email
 3  Fibromyalgia My first 2 weeks on Savella went very well. My pain was significantly reduced. I hoped that it would help with the fatigue, which makes some days impossible to get through. It didn't help. At the start of week 3 I developed a very bad headache, blurred vision, pound heart, pressure in my ears and my emotions were up and down. Feeling depressed, anxiety, sad and sometimes just a blank feeling, which is the worst. On week 4 now and reduced my dosage in half. I will be talking with my RHEUMOLOGIST tomorrow. I really pushed my doctor to give me this medication. I was on cymbalta for several years, it didn't do much for my pain but did help with depression and anxiety. I hope it's working for others but without all these side effects. God luck and God Bless F 47 5 days
50
7/19/2016
Email
 2  Fibromyalgia RX was very effective with decreasing the generalized fibro pain, but was extremely pricey and caused profound fatigue, drowsiness, and cognitive deterioration- to the point I had trouble running my coffee pot or trying to remember how to get from point A to point B while driving. My MD stopped the Med and I have so much more energy, mental acuity, and stamina. F 57 1 days
100 mg
7/17/2016
 1  fibromyalgia Extreme headaches, blurry vision, excessive sweating to the point I was soaked during night in bed and during day. Memory gets fuzzy and all I have wanted to do is cry, which is not like me. I also feel like my insides are quivering all the time and when I go to bed I cannot get my body to relax.. I hope that some people did not have these reactions and maybe it will help them, but I cannot keep taking it and feeling this way. F 60 2 months
50mg 2X day
7/14/2016
  

SAVELLA  (MILNACIPRAN HYDROCHLORIDE):  Milnacipran is used to treat pain caused by a condition called fibromyalgia that affects the muscles, tendons, ligaments, and supporting tissues. This medication is a serotonin-norepinephrine reuptake inhibitor (SNRI) that works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).   FDA Approval Date: 2009-01-14 (Sources: U.S. Centers for Medicare Services, FDA)

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