SAVELLA Reviews (MILNACIPRAN HYDROCHLORIDE)Average Rating: 3.0 (158 Ratings)Filter ResultsCompare SAVELLA with similar:
Type: Rx Drug
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Results are sorted by Age oldest to youngest. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on SAVELLA: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR SAVELLA | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 1 | fibromyalgia | tachacardia severe, chronic diarrhea, . headache every day with flushing and hot flashes,breathlessness constantly during slightest exertion..scalp itching and loss and thining of hair by handfuls. | paired with brilinta (60 mg. twice a day) the breathlessness was unbearable..not worth the side effects for me...not one drug I have taken has helped with 30 years of fibromyalgia | F | 80 | 21 days 50 mg 2X day | 6/16/2021 | 2 | Fibromyalgia | Hair loss/thinning | Helped mental state somewhat, but has not helped at all with pain, especially wide spread nerve pain. | F | 71 | 3 months 50MG | 7/16/2017 | 4 | fibromyalgia | I started med as precribed up to 50mg twice a day,(tried to go up further but could not). I had nausea for the first 3 months. Cut back to 25mg twice a day. Had relief for constant aching and pain from scale of 15(yes my pain was bad) to maybe a 2. Side effects included insomia, constipation, skipped beats to the point of having it evaluated, and high blood pressure which didn't response to medication much, occasional zings in my head. Decreased dose to 12.5 twice a day and had some improvement in side effects and still had relief of pain. I always called it a wicked drug due to the side effects. After a year and 3 months I slowly weaned myself off of it and have kept my pain at a tolerable level which I can take excedrin or ASA. B/P has gone to 117/69, heart rate to 80 and no longer have irregular heartbeats.Would never go back on due to side effects. | F | 63 | 548 days 12.5 2X day | 6/12/2011 | 5 | CFS | I'm the 62 year old male who recently posted about Savella. It did wonders for my cfs but adversely affected my heart. To update: The cfs problems returned within 2 days of ending Savella. Now I'm on Norco 5mg, twice a day, one in morning and one in the afternoon. It does a good job of knocking out the pain and fatigue. I know people go nuts when you mention using an opiate because of the addiction potential. They need to back down. I intend to stay on the Norco as long as my m.d. allows. | M | 62 | 6 weeks 50mg 2X day | 5/11/2012 | 5 | CFS | Savella did wonders for my CFS. It knocked out 90% of my fatigue problems. But I had to get off it. It substantially increased my heart rate. The blood pressure went up, too. My cardiologist wanted me off it. I'm on a pacemaker so I have a danger of other heart problems so there's no need to aggravate my heart. | I'm hoping against hope that the CFS doesn't return. Savella is a good drug for CFS. I, unfortunately, had a side effect that wasn't tolerable. | M | 62 | 6 weeks 50mg 2X day | 5/9/2012 | 1 | Fibro | Profound and incapacitating memory loss that occurred gradually over time. Got so bad I could not remember how to run my coffee maker. MD thought I had Lewy bodies but mercifully the MRI was fine. Dangerous medication with memory issues during the drug trials but somehow still got through the FDA. | F | 61 | 2 years | 6/4/2020 | 5 | FMS | HBP, disorganized thinking, irritation and impatience, high levels of joint an muscle pain with each dose increase for about 3 days | My husband and I are both on Savella for FMS. I tend to be depressed and anxious, he tends to be depressed and flat in affect. I started 2 weeks before him. I had high blood pressure, and the other side effects mentioned but stuck with my dose. He had high blood pressure and the same side effects; but he went back down to 12.5/day on his dose. He is coming off Cymbalta 10 mg qd. He ran out of Cymbalta and two days later started taking Savella at 12.5 qd. 5 days later he went to 25 qd. His blood pressure and heart rate increased. Instead of moving to twice a day dosing, after 2 days he opted to cut his dose to 12.5. His BP has remained high with the reduction. He is having a lot of memory issues and his pulse is 102 compared to a normal level of 68. I am on twice a day dosing at 12.5 per dose and am feeling much better. If I am late on my dose, I feel agitated and hyper, though.I put my gender down as male since I am mostly reporting on my husband. There are no male reports so I am hoping to see some soon or to see someone check in on their progress. The posts are mostly pretty old. | M | 60 | 21 days 12.5 2X day | 5/11/2010 | 1 | chronic pain | Let's see, where do I start? I was on Savella 2 weeks before I called my dr. and said I couldn't tolerate it any more. Scalp tingling, rapid heartbeat/palpitations, hot flashes. Then I mistakenly took an NSAID (ibuprofen) and have been bleeding an entire week, even after stopping the drug. I found no relief whatsoever, and because of the bleeding, I cannot take anything else that might get me through the pain. I have extreme headaches, shoulder and neck tightness and pain, but until I can reach my dr. again, I can take nothing for my discomfort. | F | 60 | 14 days | 1/30/2010 | 1 | fibromyalgia | Extreme headaches, blurry vision, excessive sweating to the point I was soaked during night in bed and during day. Memory gets fuzzy and all I have wanted to do is cry, which is not like me. I also feel like my insides are quivering all the time and when I go to bed I cannot get my body to relax.. | I hope that some people did not have these reactions and maybe it will help them, but I cannot keep taking it and feeling this way. | F | 60 | 2 months 50mg 2X day | 7/14/2016 | 4 | fibromiagia | Started out with bad hot flashes,sometimes bad headaches,but the worse is my memory. Loose tract of what I say, can't find the words to say what I want,can't remember one day to the next, can't remember conversation's I had. I can't remember period!!!!! The worst is driving,and I can't remember where I'm at, or where I'm going,scared me half to death!! Dr says normal for my age. I feel like I have Alzheimer's!!!! | If I can get past being stupid in the memory department, yes Savella has helped me to get out of bed, pain wise. I can do more without the pain, but if I overdo I pay dearly the next day. | F | 59 | 2 years 50mg twice | 12/16/2015 | 3 | Nerve pain in my leg | itchy scalp, insommnia, enlarged prostate, weight loss, frequent night time urination with interrupted flow. | I took Lyrica for over a year and my physician recommended I try Savella because I wasn't getting much relief for the pain. I haven't seen any change in pain with Savella either but I'm getting side effects that I never had with Lyrica. | M | 59 | 2 months 50mg. 2X day | 3/23/2011 | 3 | none yet, but are still just on the 12.5 twice a day | not so sure about it, also take methadone so am really concerned about combining the two medicines | F | 58 | 8 days 2X day | 7/2/2011 | 3 | body pain | Extreme sweating! Whole head would get wet and it would drip down my back. This stopped when I totally got off the Savella. | It did help with pain. | F | 58 | 60 days 50mg 2X day | 8/3/2010 | 2 | Fibromyalgia | Excessive sweating while feeling cold to touch. Heart racing and beating very strong. Blood pressure became dangerous also. Constipation and the feeling that bladder was leaking. | It took most of the muscle pain and nerve pain away and it was good to be able to get right up out of bed in the morning, but those side affects are worse than I have ever experienced with a drug. | F | 58 | 50 days 25 mg. 2X day | 9/9/2010 | 1 | fibro pain | pain in abdomen, night sweats, compulsive crying, bad mood, sores on skin,palpitations, anxiety,headache,dry mouth, agitation | I was on Pristiq 50 mg/day with good effect on my fibro. Even though it is not listed for fibro. I also have depression with anxiety. MD suggested Savella as it is for fibro. Took the full 50 mg twice a day for 3 days so far. Not helping...more pain in legs and chest muscles, some shortness of breath (not activity related) and other symptoms already mentioned. I am not going to take this med any longer. I cannot spend my life crying. I will go back to my Pristiq. This Savella is killing my gut. I am on Celebrex also and cannot take the combo of both of them. I feel very anxious. | M | 58 | 4 days 50 2X day | 9/15/2010 | 4 | Fibromyalgia; nerve pain | Had tried Lyrical with unhappy results( constipation, head spinning, sudden hair loss, bloating). Rheumy suggested I try Savella. No constipation this time ( ialso had IBS which errs toward constripation)...in fact I think I am going more often. Sometimes I get a tingly feeling in scalp. Blood pressure only pre-hypertensive when I check it at work once a day. Get occassional lightning type headache...but also have that from nerve injury due to a fall I had 2 years ago. | I am not feeling as achy or least less aware that I am hurting all over particularly in my spine. I promised my rheumy I would try it for 5 or 6 weeks this time. So far...not too bad. | F | 57 | 14 days 50 mg 2X day | 12/11/2010 | 2 | Fibromyalgia | ringing in ears, constipation, depression-uncontrolled (depression was moderately controlled prior to taking Savella) | Savella has not worked for me. It did at first, but after my body got "used" to it, the dosage had to be raised for effect (x2)and the same thing happened...worked for about 2 weeks, then stopped working. | F | 57 | 6 months 50 mg 2X day | 2/18/2011 | 2 | Fibromyalgia | Weight loss (yeah!), couldn't take a nap during the day no matter how hard I tried. Harder to sleep through night even though I'm on a prescription sleeping med. | Savella replaced Gabapentin and Doxipen along with my anti-flammatory med put 40 pounds on me which I could NOT take off. I lost 15 lbs without even trying, kept 10 of them off. Switched back to old meds because Savella didn't control the pain nearly as well. However, it really helped the chronic fatique during the day. However, I'm sleeping better at night now without it. | F | 57 | 5 months 60 mg 2X day | 2/27/2010 | 2 | Fibromyalgia | RX was very effective with decreasing the generalized fibro pain, but was extremely pricey and caused profound fatigue, drowsiness, and cognitive deterioration- to the point I had trouble running my coffee pot or trying to remember how to get from point A to point B while driving. My MD stopped the Med and I have so much more energy, mental acuity, and stamina. | F | 57 | 1 days 100 mg | 7/17/2016 | 1 | fibromylagia | Awful side effects. Hot flashes or Hot flushes and nausea-- | F | 57 | 60 days 25 to 100 1X day | 7/27/2010 |
SAVELLA (MILNACIPRAN HYDROCHLORIDE): Milnacipran is used to treat pain caused by a condition called fibromyalgia that affects the muscles, tendons, ligaments, and supporting tissues. This medication is a serotonin-norepinephrine reuptake inhibitor (SNRI) that works by helping to restore the balance of certain natural substances in the brain (neurotransmitters). FDA Approval Date: 2009-01-14 (Sources: U.S. Centers for Medicare Services, FDA)