PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction lowest to highest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  ocd, anxiety If I skipped a dose the side effects were vertigo, confusion, brain zaps, a ch-ch sound in my ears, psychotic episodes, anger...the list goes on! F 31 8 months
50 mg
2/7/2012
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 1  Anxiety/Depression (Mild) I only took a quarter of the dose recommended by the "psychiatrist" I saw, and didn't feel anything for the first few hours, then my tongue started to feel like it was too big for my mouth and my throat felt constricted. Through the afternoon, I started to feel like I was falling away from the world, almost as though a barrier was blocking me from everyone around me. This made me feel quite overwhelmed. That night, I could not get to sleep for about 4 hours, then woke up at intervals of approx. 1 - 1.5 hours. The morning after, I decided that feeling like I was choking and slowly being shut off from the world was not something I wanted to face for the two weeks the psych said it would take for the drugs to settle and really did not want to face the withdrawal symptoms of coming off Pristiq after that long. I cannot imagine why anyone would prescribe 200mg of Pristiq as an initial dose to someone who only has mild depression anxiety! F 20 1 days
50mg 1X day
1/22/2012
 1  anxiety i started off with the common side effects of nausea. after a week or two that went away and i was feeling great until about week 7 on this. i got every side effect possible. headaches were the biggest problems especially in back of the head, tight jaw muscles, major naseau, anxiety level went throught he roof, then i was getting intermitant headaches and intermitant periods of euphoria. i have been off of the drug for a week now and it has been hell for side effects for withdrawl. all the ones i listed above but the other night i felt like i was going into a ceasure. symptoms are better ow but i would not take this drug ever again. M 38 12 weeks
50 1X day
1/17/2012
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 1   There is NO reduced serotonin or chemical imbalance. The idea of the psychiatry is to reduce unwanted behaviours (mental illnesses such as depression, schizophrenia) by 1) torture, 2 death. Everything else is a lie. In psychiatry mind is "sick", similarly to joke is sick. Psychiatry typically reduces symptoms by causing brain damage. Paranoia is quite common in mental health patients, people are "helping" you. For sources of depression you have to find REAL physical or NEUROLOGICAL problems and treat them. M 30 1 days
50 1X day
11/16/2011
 1  Depression/Anxiety I have tried many different antidepressants and this was the WORST! I felt like a different person. My personality pulled a 180 and a crazy person was born. I was SO paranoid I had to lock myself in my bathroom when I was home alone. I have always got straight A's and have never been in trouble. After being on this drug I completely blacked out and started doing things completely against my morals. I was arrested and had to pay over $1000 and I am in the system. The doctor took me off of it and ever since I have been my old self. F 20 6 months
100mg 1X day
11/3/2011
 1   Extreme anxiety, shaking, depressed, loss of appetite, dillusions, completely irrational thought patterns ALL I CAN SAY IS PLEASE DON'T TAKE THIS POISON. If you want to cross over to the dark side, this is the med for you. I only took 2 doses and I was effected for a full week and I honestly thought I was in hell!! I became extremely irrational and withdrawn from my family and everyone around me and it gave me far more depression being on it than before I took it!! Also brought back suppressed memories, awful awful drug. F 35 2 days
50mg 1X day
10/30/2011
 1  depression Severe headaches, anxiety, severe nausea, unable to see, muscle spasms, chills, odd body pain, gastointertinal pain, bloating, racing heart, disorientation, aggravated dyslexia (severe), eye pain and pressure, pressure in neck arteries, brain *zaps* and odd sounds in ears, extreme thirst, sleeplessness ***DO NOT TAKE PRISTIQ!!!*** I had one dose in july; atypical migraines. Could not get ahold of my Dr, took Maxalt w/ the drug and thought I would have a stroke, along with the other symptoms. It is now the end of October and I have been sick with almost every *rare* side effect listed, currently a lung infection. My health went downhill the day I took this med; DO NOT TAKE IT!!!! Do not let a family doctor Rx it---find a good Psych Neuro. My Neuro said the drug is so new, they have NO IDEA what problems it causes. This drug will kill people--plus it was never developed for this use; look up Ellefore, which originally was sold as a non hormonal replacement for menopausal woman. The UK did not approve the drug. Wyeth should have to live through the hell I have been through, and I ask---when does this quit??? F 51 1 days
50mg 1X day
10/30/2011
 1  Anxiety/panic attacks Inreased heart rate, constant anxiety, increased panic attacks I HATE this med (I mean POISON!!). I have only been on it for 30 days and I feel like I am going crazy!! My anxiety and fear are worse than they have EVER been. I used to only need to take a small dose of Xanax 0.25mg). as needed, but since starting on Pristiq, I am taking a total of 1.0 mg or more a day, just to deal with this increase in panic and anxiety! I have weird, vivid dreams and wake up several times during the night with a racing heart which then of course spirals into a panic attack!! I am weaning myself off this crap starting today! STAY AWAY FROM THIS MED!!!!!!!!! F 40 30 days
50 mg 1X day
10/17/2011
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 1  depression Loss of concentration and focus, fuzzy headed, loss of hair, insomnia, weight gain, headaches, fatigue, irritability, no sex drive, shaky, zombie like emotions, no desire to be around other people, HORRIBLE - HORRIBLE DRUG. It seemed to work okay at first then after several months it went down hill fast. The very worst part of this drug is coming off of it. THE WITHDRAWALS ARE EVEN WORSE. I was not taking any other meds and was only on 50 mg a day, but when my doctor and I decided to wean me off of them -- I was close to suicide for the first week. PLEASE do not consider this drug. I will never take another antidepressant ever again because of my experience with this vicious drug. I would rather deal day to day the best I can than go through this. I am on my 8th day and a bit better, but still having a very hard time with puking, diarrhea, headaches, vertigo, blurred vision, no energy, my hair is falling out even more now! PLEASE PLEASE PLEASE avoid this medication -- take something else!!! F 49 2 years
50 mg 1X day
9/29/2011
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 1  Mild Depression/Mild Anxiety memory loss, loss of motivation, increased thoughts of suicide, increased depression, disoriented, forgetful, sleeplessness Overall I really feel this med set me back years in my stuff I was working on. Now that I have been off of it (and any other med) I am feeling like a recovering alcoholic with the work I have to do. F 37 1 years
50mg 1X day
9/27/2011
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 1  Depression/Anxiety Dilated pupils, heart racing, jittery, diconnected, loss of sleep and feel tired at the same time (tired and wired) loss of orgasm, loss of appetite, confused and foggy, blurry vision at times On this drug for 2 days and felt wierd. Dilated pupils were very annoying and I didn't sleep after the first pill so today I am so tired. Feel foggy, disconnected and I'm sure this is partly from no sleep. Just called the Dr's office they said disc. b/c of the many side effects already. I wonder if I stayed on it a few months how I'd feel but to scared to find out esp after all the other bad reviews! F 35 2 days
50 1X day
9/13/2011
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 1  Major Depressive Disorder and GAD Weight gain and an inability to lose weight, despite frequent exercise. I crave food constantly, always feel hungry, especially for sweets and carbs. My anxiety is worse, I constantly fidget and cannot keep still. I feel numb on this med and drained of creativity. I cannot cry over things which matter but tiny things will make me bawl my eyes out, like a television commercial! I really wouldn't recommend this medication to anyone, it's been a horrible six months :( F 26 6 months
50mg 1X day
9/5/2011
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 1  Depression/anxiety Complete loss of sex drive, intense dreams, SEVERE sweating i will NEVER let any one I know take this poison. The side effects far exceed the "benefits". And if you miss a dose, you literally go insane. Complete withdrawal from this drug is the hardest thing I've ever had to do. Realizing what this drug has done to me, I will never take it again, even though I am dying with out it right now. I feel like I'm constantly being electrocuted. I strongly feel the FDA will pull this poison off the market soon (not soon enough) and there will be many law suits. But nothing will make up for the life lost for all the people that are suffering, and have suffered, from this drug. F 24 4 months
100mg 1X day
7/28/2011
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 1  PRE TENSION SYNDROME Foggy headed, out of control Never taking this again!! I am going back to birth control and ADD meds I am not depressed and told the doctor I just have ups and downs 2 weeks before my period! F 27 1 days
50 1X day
7/26/2011
 1  Anxiety/Panic Disorder 2 doses = Suicidal thoughts. My "doctor" gave it to me for panic disorder. By the second day, I had witnessed worse panic than anything my disorder was able to do to me. Absolutely horrific. Thank god I stopped after two days, and it still took me 4-5 days to shake the after-effects of that poison. Everyone is different. Maybe this will help some people, but it was a nightmare for me. M 42 2 days
50 MG 1X day
7/21/2011
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 1  depression Extreme craving of sweets and carbs. I had been on a low carb alkiline diet and was fine and losing weight with no cravings for the sweets and carbs. As soon as I went on pristiq, there was no end to the horrible hunger pangs and I could not get eat enough sweets and carbs to satisfy the hole in my stomach. I felt foggy and confused at times over making even the smallest decisions. I had trouble sleeping through the night. I felt nervous and agitated. After 7 days on this drug I am going off of it before the horrible withdrawal symptoms kick in that I'm reading about. Hopefully I am stopping it before that happens. I do not recommend this drug. My doctor assured me it would not cause weight gain, but the hunger pangs that started within one day were unbearable and the only change to my life was pristiq. Do not believe the spiel about no weight gain and no affect on libido. It isn't true. You are the guinea pigs for this new "miracle" drug and it will come out later, that, yes in fact it does cause weight gain and affects sex drive. Don't take this drug. F 57 7 days
50mg 1X day
7/15/2011
 1  Depression, anxiety Severe depression, akathisia I've tried many drugs, and this is absolutely the worst I've ever taken. M 35 1 months
30 mg 1X day
7/4/2011
 1  Anxiety Disorder, Depression Intolerable anxiety, three months cringing in bed,18 months later and eight medications to bring it down to "tolerable". I included some "essential" reading in my comments. Best of luck ... ... After I went off Effexor (375mg) my depression returned, and my "high reputation MD" insisted on 100mg of Pristiq (aka "Effexor or steroids"). After I was in "severe anxiety", he raised it to 275mg ... ... and I wound up "cringing" in bed for three months, while he kept insisting the two were identical (I'm convinced there was a kickback). After some research, I switched MD's, went on Effexor, and we finally found the “eight” medications that “reduced” the side effects to “tolerable”. It’s now 18 months later, and I still feel like I'm plugged into an electric socket. If considering, or on, Pristiq, essential reading, "Top 5 Reasons to Forget about Pristiq" by Dr. Carlat, a prof atTufts Med School, (www.carlatpsychiatry.blogspot.com/2008/03/top-5-reasons-to-forget-about-pristiq.html) … ... the lawsuit at www.i.bnet.com/blogs/pristiq-complaint.pdf for (great info on Wyeth's future without Pristiq) … ... and google “lawsuit pristiq”. BTW When I asked the orig MD why he insisted on Pristiq, “because it has fewer side effects”. The SOB was white and shaking after I said “you %^&, I didn't have any side effects with Effexor. If it were me, I’d insist on Effexor (and don’t give Wyeth your money, get the generic). M 57 3 months
275 1X day
6/14/2011
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 1  Anxiety Insomnia, uncontrollable shakes, jaw clenching, dialated pupils, manic, fast beating heart. After one dose of this deplorable medicine, I decided to desist right away. Never before have I been in such a weird head space. I'd rather be miserable than take this stuff EVER again. M 19 1 days
50 MG 1X day
5/5/2011
 1  Anxiety/Depressive tendencies Loss of sex drive, Anxiety, Panic attacks, Suicidal thoughts, Depression, Aggression, Aggitation, High BP, Nightmares Taking this drug has been a distressing experience. The side effects have outweighed any possible benefits of taking Pristiq. I would not recommend this to anyone. I missed a dose and found myself in the ED with the worst panic attack of my life, I felt like I was going to die. I have sinced weened off this drug and it has been a nightmare to say the least. Dizziness, anxiety, body aches + cramps, lethargy, aggitation..just to name a few. If you choose to take any AD be sure your Dr discusses withdrawals with you - they are hell F 23 6 months
150 mg 1X day
5/4/2011
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