PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction lowest to highest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  depression Weight gain, gained 9 pounds in 9 Weeks, dizziness at times and by 9th week severe swelling of upper and lower extremities. stopped Prestiq today and went back to Prozac as directed by my doctor. F 50 9 weeks
40mg
7/7/2012
 1  Anxiety On day 8 I had my first of many panic attacks and intruding thoughts. Thoughts that I could hurt myself or someone else... I was assured by 2 pharmacists, a dr and a crisis line councilor this was all the result of pristiq. It is now 4 days later and 95% of the intrusive thoughts are gone, they do still randomly come into my head. And I was given clonezepam to control the panic. I stopped taking this nightmare of a drug 4 days ago as well. Just a few more days till it is completely out of my system. F 34 8 days
50
7/2/2012
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 1  Depression and Anxiety Withdrawals if forget to take prescription - dizziness, headaches, vertigo, cloudy feeling. Other side effects: loss of emotions, loss of sex drive. PLEASE DO RESEARCH BEFORE GETTING PRESCRIBED THIS MEDICINE - MANY PEOPLE HAVE HAD TERRIBLE ISSUES WITH IT. I am currently in the process of getting off this medication because of the awful side effects. F 25 3 years
100 MG
6/12/2012
 1  Generalized Anxiety Disorder (GAD) Weight Gain, Bruising Easily, Fatique, Lack of Energy, Forgetfullness, Dizziness, Headaches, Decreased Sex Drive I gained 40 pounds over the course of two years taking Pristiq. The first time I took it I noticed almost immediate weight gain. This was over the course of almost a year. I went off the medication and noticed my weight start to decrease. My doctor put me back on the medication about six months after I went off it because I experienced some family trauma. I gained all of the weight back and then some. I have to say that I am more depressed being on the Pristiq than not. Mostly, due to the weight gain. I have always been thin all my life and contribute my weight gain 100% to taking this medication. Over the past few months I have put myself on a diet and increased my exercise and that has not helped. The scale does not change no matter what I do. I don't have the same energy I once had and are tired all of the time. I am looking forward to my life without medication and practicing a clean lifestyle. F 28 2 years
50 1X day
6/11/2012
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 1  Depression Jaw clenching, choking sensation, dry mouth, loss of appetitie, weird dreams, hyperactivity, spacey head, shakes, a feeling of something crawling on my leg, it goes on and on. THIS DRUG IS NOT SAFE. The first day I had a high like I'd been smoking pot all morning. The fact that this stuff is legal and a PLANT FROM THE EARTH isn't just blows my mind. I took this for two days. I'm on day three and didn't take the 3rd dose because I feel LIKE IM TRIPPING ON ACID. I hate it. This drug is horrid. F 37 2 days
50 MG 1X day
6/5/2012
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 1  Depression / anxiety Weight gain! 30lbs in one year. Nausea everyday, stomach cramps, extreme fatigue, aches and pains, teeth grinding, locked jaw, a feeling of not feeling or caring about anything, lethargy I just had a meeting with my doctor who could not explain why i have gained so much weight and am feeling ill all the time. With this information we are now working at slowly weaning me off this horrible drug. F 34 1 years
5/17/2012
 1  Depression/Anxiety Joint pain to the point of not being able to walk or carry anything. Itching to the point of scratching my skin off. Tired, Irritable, Moody, No normal sex drive, foggy brain, headaches, nightmares, blurred vision, disorientation, insomnia, swelling of feet and hands - couldn't wear my wedding band or any rings without problems. My doc that prescribed this horrible little pill sent me to a specialist for shots for the joint pain and I received more than one set of shots in hips and shoulders - couldn't move for days - even more pain. I have had everything checked from my Thyroid to being checked for Lupus with all of these symptoms!! Oh, and my insurance would not cover the shots that both my doc and the specialist thought I needed and that put me out over $2000.00!! This has been a nightmare that has finally ended because the Good Lord told me to stop taking this poison!!! I weened myself off of it over about 3 weeks to avoid the horrific withdrawal symptoms that I had read about! I am a Breast Cancer Survivor and now after all of this time - 3 years since my Cancer - I am finally starting to feel better!! If you value your quality of life and your health - DO NOT TAKE THIS MEDICATION!! I am glad to have figured out what was causing all of the problems and that they are gone; however, so pissed off at my doc of more than 10 years that he did not figure this out or just didn't care! F 45 17 months
100mg 1X day
5/16/2012
 1  Depression Severe headaches, severe muscle pain, weight gain, blurred vision, itchy skin, increased lack of focus (since I already had a problem with that) and I became extremely moody The 1st week I was on this I started getting the chills really bad all day long. Then when I would try to go to sleep I would sweat horribly all night long and have intense stomach pain so bad I wanted to vomit. Also my nose clogged up and got little sores in the openings of my nostrils on both sides. The 2nd week my muscles started to get really really sore to the point walking across the room was exhausting and made my heart pound and then I would be in utter agony because every muscle in my body ached so badly. A couple weeks after that my jaw started locking up and I started getting very intense headaches that no amount of pain killer could help. But I'd started 2 other meds so I had no idea this was the one causing it. So my doctor finally just took me off this one. She tried to wean me off of it by putting me on a low dose of effexor for a week but this withdrawal is no picnic. Dizziness, brain zaps, irrational anger and can't sleep. But my head aches are far less painful and my muscles are getting a little better hope the other problems start to clear up. This definitely needs to come off the market! This has killed my health and my doc said it was brand new when she prescribed it. F 25 5 months
50 mg 1X day
5/10/2012
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 1  depression Loss of tactile sensation, Sweats, tingling in legs, weakness, lack of desire to do anything. I felt nothing. I didn't feel bad, but I didn't feel good. I felt as though I had no soul. This frightened me. M 34 2 days
50 MG 1X day
5/9/2012
 1  depression have suffered for ten months with severe diarrhea. 6 to 12 times a day. am homebound due to it. Had to have colonoscopy, endoscopy also 72 hour fecal test and several other fecal tests. developed blood in urine , insomnia, anxiety,Last week had an abdominal ultrasound and also a cat scan in the E.R. four doctors are looking at this now and had me stop taking the Pristiq.. Withdrawals are awful with brain zapping and feelings of anger. I would never take this drug again Have been weaned off it totally 2 weeks now and still have the diarrhea. My gastroenterologist suggested since I have WBC in my stool that a biopsy for microscopic colitis may be the next option. He also said I may need the Mayo Clinic. How the heck can this drug be on the market? I have never had any of these problems before taking Pristiq. F 63 13 months
50 mg 1X day
5/8/2012
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 1  Depression/Anxiety nausea, loss of appetite, insomnia, constipation. On day 1, I could not sleep at all. I was shaking...I felt crazy. My thoughts were very loud, and I could not stop doing things. I crashed the next day. Then the yawning started, and the muscle twitches in my face. Everytime I yawned, my mouth was pulled into a frown or just jerked repeatedly. I did not eat the whole 4 days. I stopped cold turkey and have had no problems, except the anxiety feels a little worse in my chest. F 34 4 days
50 MG 1X day
5/5/2012
 1  anxiety and hot flushes (menopause) side effects-weight gain (carbs and sugar) sweating, strange dreams was taking this for hot flushes, and low and behold this makes you sweat. Also I have high blood pressure and again, this makes your blood pressure go up. I dont think these Doctors know what goes on. F 49 4 months
50mg 1X day
4/26/2012
 1  depression, anxiety vomiting, dizzyness, sleepyness, i felt dopey and could not concintrate, weightloss, blurred vision, headache, the first day i started taking prisiq i instanly felt so sick, i couldnt drive, work or do anything, i felt like spewing all the time, i was dizzy, could not eat and just wanted to sleep all the time. this did not go away and was getting worse with each dose i took, i stopped taking them and now have insane withdrawal symtems i have all of the about but they are now worse, i cant work, drive of pretty much do anything, my husband says that i look like a zombie, i have not eaten a proper full meal since starting these.. how long is this going to last??? i have been off them for a week know and there is no improvement... :( F 22 5 days
50mg 1X day
4/23/2012
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 1  depression/anxiety While taking the drug it seemed OK. It definitely was not a cure all and recently I have been switching my approach to more counseling and weaning myself off of all meds. The weaning from Pristiq has been TERRIBLE. I have had extreme dizziness, memory loss, sensitivity to light, extreme irritability and anxiety. I was told by my MD that it caused the low blood pressure and light headedness that caused my to lose conscienceness and wreck my car. I advise extreme caution tapering off of this drug. I have not found many medical professionals who prescribe Pristiq. The Cleveland Clinic advised me that they do not prescribe it. I do not recommend this anti-depressant. I've been on many of them and have never experienced the side effects when stopping any of the others like I have Pristiq. I think it is a very dangerous drug. F 31 6 years
100 1X day
4/3/2012
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 1  Severe Depression Insomnia, Hives, Rashes, Skin crawling, MAJOR Hair Loss (I'm a girl... not okay), Blurred vision, Migraines, Paranoia, Manic State PRISTIQ was/is the worst this that has ever happened to me. I have been off this **ing drug for almost a year, and I am still experiencing withdrawl symptoms/ my body is just getting back to normalcy. When I was on Prisitq, I think I had a SEVERE allergic reaction/ every possible side affect to the drug. The fucked up thing is how new this drug is, that my symptoms don't seem to matter and/or measure up to any scientific stats. However, this is what I know.... I have been diagnosed with depression since I was 18. I am now 21, and before Pristiq, I faced a 7 year battle with bulimia, which i overcame. The whole reason I was put on Pristiq was because I was actually doing well and overcame a huge battle with eating disorders, yet still felt the depression. My so called Doctor put me on Prestiq to help my low energy and chronic depression, when in all actuality, my doctor put me on a new anti-depressant so she could make bank, while i was sent back to CA, where I went to school (had to withdraw bc of Pristiq) --- my story is complicated and long, but one fact holds true- PRISTIQ ruined my life. As a young woman of 22, with a 7-8 year history of anorexia/bulimia, I am currently going through Post-Traumatic Stress Disorder from a drug that was suppose to make me BETTER. I cannot in any way compare how awful the few months on Prestiq were to my life long battle with Eating Disorders. The year I spent on/withdrawing from Pristiq was the worst of my entire life and I would not wish F 21 6 months
50 mg 1X day
3/18/2012
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 1  Depression At first it was wonderful! Until about month 3.... I started experiencing decreased sex drive and HORRIBLE increase in appetite. I gained approx. 20 lbs. in only 4 months. Once I decided to stop taking Pristiq I stopped all at once and experienced Horrible Dizziness and diarrhea. The benefits of this medication definetly did not out way the side effects. F 26 1 days
25mg
3/17/2012
 1  Anxiety Weight Gain! unable to lose weight. Agitation. Tried to come off a few months ago (cold turkey/bad idea) Felt very strange for 2 days without. Now taking in halfs and am going to come off slowly. F 34 9 months
50mg. 1X day
2/26/2012
 1  Depression/ADD I talked to my doctor, described all the symptoms of ADD, and she put me on this anyways. Things stay EXACTLY the same, still depressed, still unable to focus. I demand to be treated for ADD, things get immensely better...I can focus and get things done for the first time in my life since I was a 3rd grader, but theres still this unnatural lack of energy plagueing me, and my weight keeps going up, despite weight-training, cardio and a healthy diet. I give thought that it might be the Pristiq, but am not too worried about it. Lethargy gets worse, insomnia gets worse, but I attribute the insomnia to the adderall, so I don't take it for a couple days...insomnia is still there. At this point I want to experiment with taking a small break from Pristiq...and am immediately thwarted by electric-zap feelings like my brain is a tesla coil, am incredibly irritable, dizzy, and nauseous...the VERY next day. I wasn't warned, and when I attempted to tell others about these withdrawl symptoms noone took me seriously, so I stayed on it. Well, I've been on it for over a year, and am now into week 2 of going off it, and the symptoms are. not. going. away. Everytime someone says "you should taper it with smaller doses" I feel like punching them, because there are no doses smaller than 50mg, and it's time-released, so you can't break it up. A major doctor from the company admits this drug is terrible, so why are we being prescribed this poison? Don't take it. M 25 1 years
100mg
2/26/2012
 1  Switched off zoloft Weight gain, mood swings, lack of energy, angry, loss of memory F 35 3 months
30 mg
2/21/2012
 1  anxiety dizziness,low sex drive, weight gain The only thing that helped me to come off Pristiq, was using scopolamine patches. They are prescription, but could not have done this w/out them. I tried quitting once before and couldn't because the dizziness was horrible. The scopolamine patches didn't completely get rid of the dizziness, but compared to the time before when I tried to quit, such a huge difference. FYI-Scopolamine patches are put behind your ears. They are used for sea sickness. I also tried dramamine but it did not help. If you are trying to get off of this drug, please get the scopolamine patches. F 39 3.5 years
50mg 1X day
2/15/2012
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