PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction lowest to highest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Generalised anxiety, panic disorder Ringing ears, 'electric'like on drugs, a burning tingling all through my body, sweating, panic, racing heart,cold shivers.. . I couldn't sleep, just had to concentrate on my breathing all night. I was terrified. I only had one dose! I took it at night as suggested by my doctor. I woke about 3 hours after taking it in a weird, electric atmosphere, my head was buzzing. Then the burning tingling sensation started and lasted on and off for approx 10 hours. This was the most awful night. I felt like I was trapped in a state of panic induced by the drug. Confused, scared. Over 12 hours later I still feel very very anxious, racing heart. I was advised to go to emergency, but I've just been chatting with my nurse sister. A drink is helping me calm down. Now I'll need to miss work to go back to the doctor. This increased my anxiety and panic 10- fold. Horrible. I think it's too strong for me. Or wrong for my condition. I'm hoping it'll be out of my system soon. F 34 1 days
50mg
11/7/2015
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 1  Major depression Brain fog:- inability to think clearly, very sore tongue, yawning all the time, eye pain, dry mouth, weight gain (10lb while on this), sleepiness and unable to drive. It seemed to work at first but it was probably the placebo effect. I became very irritable and not myself at all. Small things irritated me immensely - like my partner finishing dinner before me and leaving the dining table - - this was enough to spark a major argument and thoughts about divorce. Totally inappropriate reaction. Coming off it gave me severe headaches and the way it is formulated made it difficult to taper off as well since the slow release effect is created by the pink film coating. Cutting the tablets in half to reduce dosage causes the slow release effect to not work and gives a high spike of the drug. The half life is only 11 hours so after half a day the withdrawal symptoms kick in with force. Glad to be off this. M 60 3 months
50mg
10/21/2015
 1  depressed Headaches, ANGER, agitation, others, addictive , hard to get off Just go cold turkey and deal with the headaches, it only takes a few days. The longer your on it, the worse to get off, but get off before you kill your dr F 50 3 months
9/12/2015
 1  depression pristiq gave me weight gain and headaches. I was on wellbutrin but it lost its help for me was great but was on it for 6 years. and pristiq is not generic. going back to psyc doc and get something else. pristiq is not generic. in between my insulin and other meds the higher price isnt worth it. F 47 2 months
50 mg
5/8/2015
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 1  Anxiety, depression Irritability, flat affect when increased to 100 mg, rage when drinking alcohol I was a very irritable and angry person on this drug. Not myself at all. I would get so angry over stupid things that were not worth getting upset about. I have been off of drug for 2 weeks and I am a new person that is happy. When I started tapering off my meds I had dizziness, nausea , mild headache. No brain zaps. So glad I got off drug, I feel better overall. F 29 2 years
50 mg
5/3/2015
 1  severe anxiety and depression, PTSD Over the years I've suffered from depression and anxiety. I've been on several different medications. Pristiq has made me very paranoid, restless, and agitated. I have lost all interest in activities. I spent most of my days in bed afraid to leave the house. Had spliting headaches and insomnia. My eyesight changed for the worse. Extremely fatigued, dizzy, loss of appetite...but experienced weight gain. Very bad side effects in general. Horrible when discontinuing use. Caused neurological issues. F 31 10 months
100
4/23/2015
 1  Posting on behalf of my father Worsened anxiety Worsened bipolar Extreme detachment Suicidal I am so happy I found this site after seeing what happened to my father (in his 50's). The reviews that come up when one googles this drug seem completely misleading until you dig a bit further. My father was switched from Lexapro to Pristiq for his bipolar when Lexapro stopped working. What happened after a few weeks was enough to scare the whole family and every acquaintance of my fathers. It was like he was a walking zombie with no feelings other than negative and irrational ones and turned verbally aggressive to everyone. His lows were lower than ever, and his manic highs were returning. How can one drug such as lexapro work so well (before tolerance sets in), and pristiq do so much damage. In the end the only choices left were to either have him admitted to get help and commence legal proceedings against the manufacturer, or have him come off willingly. Luckily, after a few devastating incidents caused by his behavior to friends and family - he agreed to come off the drug. Coming off the drug however has posed new problems that never occurred with Lexapro. All that matters is that he has finally listened to the family about his destructive behavior on this drug and we are all slowly working together as a family to get some stability back. I still don't understand the adverse reaction when other antidepressants worked fine for him. I have a really uncomfortable feeling that the true dangers of this drug will not be made public for years until a class action is filed. 54 4 months
150 1X day
4/7/2015
 1  moderate depression Insomnia, loss of labido, nightmares,mood swings, headaches,feelings of insanity. Hated this drug. Early on I felt wide awake to the point where it felt like my eyes could not open any wider if I tried, and only couple hrs sleep. Horrible vivid nightmares that I would think about most of the following day. Totally negative impact on my mild depression.i advise to avoid!!! M 42 6 weeks
50mg
4/3/2015
 1  depression Withdrawal effects are absolutely awful. The worst I've ever experienced. I get such anxiety when I realize I forgot to take it because I know I'm going to be so sick. Dizziness, vertigo, nausea. The only way to get rid of it is to take it and sleep for a few hours. F 22 3 years
100mg
2/16/2015
 1  PTSD depression Lack of sex drive, aching bones , headaches , blurry vision , loss of balance, irritable Taking pristiq has been the biggest mistake Ive ever made if I miss just one day I will begin to feel that my brain is floating in my head! Sorta of feels like electric zaps in my head that makes me get blurry vision splitting headache I have tried to come off pristiq slowly and I ended up in hospital I feel like a druggie I can't live with out it :( F 27 2 years
50mg
2/5/2015
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 1  Mild anxiety Lack of caring, compulsive gambling, angry outbursts, gastrointestinal problems, high blood pressure, not able to see what I was doing wrong, only able to see how I felt and not others. Pristiq ruined my marriage. My wife tried to tell me for years this drug changed my behavior and for some reason I couldn't see how really wrong the things I was doing were. Even other family members could see my behavior had changed dramatically but I was addicted and thought I couldn't live without it. M 44 3 years
50 1X day
2/4/2015
 1  Depression Insomnia, anxiety, fear, numbness, aching bones. This was made by Wyeth after Effexor had a generic. Do not take this drug as you will never be able to quit without severe withdrawals. Horrible experience. I feel numb not myself and want to taper off but fear the process after reading others comments. I don't want to do anything I am completely a zombie. F 54 4 months
100 1X day
1/25/2015
 1  Depression Depression worsened, crying spells, suicidal thoughts, anger bursts My dr wanted to try me on a different anti-depressant that's suppose to cover a large range of things. After about 3 to 4 days I felt a change but not for the better. It kept getting worse and worse. I went back and she switched me back to my old meds. F 30 3 weeks
50
1/6/2015
 1  depression Helped with Depression, but heart raced, terrible mood swings, changed personality. Became super irritable, screaming at others which is not part of my personality. The most horrific Drug I have ever encountered to get off of, After the bad mood swings. My dr. told me to take every other day and I would be okay. Became so Ill I could not stand, Vertigo is terrible, brain Zaps, Still at one week have all of the symptoms, at times unable to drive. I have gone off of Lexapro and Zoloft and nothing was ever this terrible. I will never take again. F 59 4 months
50 1X day
12/19/2014
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 1  acute anxiety No sex drive drowsiness. Loss of interest in anything. Pristiq is poison. It worked for the first say 4 months. Then it stopped working. Tried to stop taking it and the withdrawal was terrible. Brain zaps. Dizziness. Anxiety. Nausea. You name it. After I became so miserable and nearly lost everything in my life ie husband. Friends. I stopped. Cold turkey. Well its been 2 months and I get the occasional dizzy spell. But wow. Completely new person. Happy , energetic and my sex drive is back and everything is so much better. Please don't try this drug. It nearly ruined my life. F 29 2 years
50mg
11/17/2014
 1  PMS=irritability & Mild depression At 1st it was ok, but gave me an unconnected feeling, kind of too relaxed. 7-10 days before my cycle started I was either yelling at the kids or Mad at my husband, or crying over some world issue. This got better for 7 months, then it was like I was back to my self , but more agitated. I came off Pristique 2 weeks ago, I took 1/2 a pill for 2 days , then 1/4 pill for 2 days, then no more. It wasn't great, but tolerable. After 7 days with no drug, I am so irritable and agitated and it's not PMS time. I just hope it goes back to normal, as everything bad from years ago, seems to be at the top of my brain. I don't know why, but odd memories and things I've suppressed are flooding back in. F 39 9 months
50mg 1X day
10/31/2014
 1  Depression/Anxiety Was great during the first week and didn't notice any side effects during week 2 BUT then week 3 came and I want no more! I have been having the brain zapping and feeling dizzy and really off balance. I feel out of control a lot of the time and depression and anxiety seems to have worsened. F 39 21 days
50mg 1X day
10/6/2014
 1  anxiety I was put on this medicine because I was experiencing sadness.. I started taking it and three to four days later I literally lost it. Felt like I had snapped. Had a panic attack that lasted for hours couldnt even finish driving. It turned my world upside down! It has devastated my life. Been four years and I have driving anxiety so bad can barely leave my house. Before, I loved to drive and do thibgs. F 36 1 days
20MG
7/10/2014
 1  anxiety I switched from Effexor to Pristiq because the phy doc thought it is stronger. Probably is because it made my anxiety and agitation much worse to the point that i could not lie still in my bed. Switched back to Effexor XR and symptoms dissapeared. If you don't feel better or even worse don't take it, try something else i had a bad experience with it. M 36 7 weeks
50mg 1X day
5/19/2014
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 1  Panic Disorder **Do not take this for panic disorder! It was like adding fuel to panic attacks. Felt like i was on speed. Excess energy, pseudo happy too energetic but with tired weak feeling legs. Restless legs at night, waking up with tensing jaw scared shitless. Nightmares. Excessive crazy sweating. Major heart palpitation episode at night where i called an ambulance. Not good for panic attacks at all. Was hell. And more hell coming off it. Severe panic attacks worse than before i went on it. F 38 5 weeks
50mg
4/20/2014

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