PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction lowest to highest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Depression Going on this drug was the worst decision ever. They warn of potential low sodium levels however since I have been off this drug it has continued. To the point I had to be hospitalised for low sodium and have been told I will need to restrict my water intake moving forward. I never had any problems with my sodium levels prior. I also had a terrible time coming off it really bad brain zaps, anxiety, insomnia. F 35 5 years
50 1X day
9/23/2023
 1  Deprssion I WOULD NEVER RECOMMEND! Would give -1000 if I could. After taking it for 4 ish years ( now off ) I have long term hyponatremia ( low sodium). I have been hospitalised for it and have been told I need to restrict my water intake going forward potentially for the rest of my life. The side effects were painful also brain zaps insomnia and the worst anxiety I have ever experienced. AVOID!! F 35 4 years
50 1X day
9/23/2023
 1  Anxiety, depression Migraines, left side of neck pain/stiffness to the point of just wanting to lay down, sleepiness, burning eyes, ringing ears, can't orgasm, stomach pain, random muscle pain throughout body, irritable, insomnia. Id rather just be depressed and anxious. M 38 7 days
50 1X day
12/27/2022
 1  Anxiety Tremor, heart palpitations, increased anxiety, extreme emotional lability, restless energy, anger. After stopping the medication: numbness in random extremities, electric shock sensations, nausea, sharp tension headaches Made me hypomanic, was sent to the hospital, still feeling withdrawl symptoms a week later. Caused me to lose my entire personality and my livelihood for weeks F 19 45 days
50 1X day
11/8/2022
Email
 1  Major depression Insomnia, cold sweats No help at all M 54 28 days
100 MG 1X day
9/21/2022
 1  Depression Worst discontinuation symptoms of any medication I've ever tried. Pure hell. Did not alleviate depression or pain. I regret ever taking this. M 50
1X day
6/22/2022
 1  Anxiety Insomnia, lost weight, lost appetite, depression, anger, self-harm, suicidal thoughts. I have paradoxical reactions like 5% of ADHD patients. So downers bring me up. And uppers calm me down. M 34 15 days
50 MG
6/21/2022
 1  Depression At first, I didn't realize it was the drug. My depression became worse and worse, and my doctor just upped it and upped it. I was unable to experience normal joy and enjoyment in life. I lost interest in everything. I had major mood swings and was far more unstable than I have ever been in my life. Prior to starting this, I was depressed for good reason due to situational trauma. After taking this, I was depressed by everything and for no reason at all. I could not get out of bed. I went to bed at 6:00 PM. I would lay around a lot. I couldn't muster the energy to clean, take care of daily tasks, take a shower, brush my hair, or exercise. I gained weight. I was hopeless and felt like dying. I went off and had horrific withdrawals to where I felt like life had no meaning and I wanted to die. However, once that passed, I feel much better. I have major stresses and grief in my life, situational traumas, and yet I feel better than I did when nothing happened and I was just on this horribl If I stayed on this, I would be dead. F 32 2 years
250 1X day
3/3/2022
 1  Depression and anxiety Jaw pain anxiety headaches insomnia F 64 2 years
50mg 1X day
1/18/2022
Email
 1  Depression Weight gain, heartburn, migraines, shakiness I had high hopes for this med to be the one to work for me. I had a dna test to see what meds my body will respond well to and which meds to stay away from. Pristiq was the only one that came up for depression. The first month or two I had extreme nausea and dizziness and I hadnt seen a difference in my depression yet. My doc wanted to go up to 50mg but I wanted to wait. The dizziness and nausea got better so I went up to 50. Before taking pristiq I was on lexapro. It didnt help at all and made me gain some weight and caused me to get acne pretty bad. My doc said I shouldnt gain weight in pristiq. Before starting anti depressants I normally weighed between 120-125. I now weigh 157. I've cut a lot out of my diet, am eating less and eating healthier and am very active but still continuing to gain weight. This is something I have never struggled with before going on anti depressants. I meet with my med doc this week and will be asking how to get off of this med. I never had heartburn or migraines and get them frequently. Almost daily my whole body is shaky and its quite uncomfortable. F 25 6 months
50mg 1X day
5/23/2021
 1  Major Depressive/Anxiety Disorder Side effects have only increased since starting ALMOST 7 MONTHS AGO. Am now at the point my body is rejecting the pills and projectile vomiting them, haven't been able to eat barely a few pretzels a day and maybe a water bottle for a week or two now, vomiting, sweating, shaking, trembling, all the side effects plastered on the damn bottle have happened to me. I can feel the improvement in my mood I really don't wanna stop taking them but now I'm gonna have to go through the intense withdrawals because my body won't allow the pill to even start dissolving before it purges it. It knows these pills are damaging and killing my body. DO NOT. DO. NOT. TAKE THESE PILLS. I trusted the medical system and their judgement and im close to being admitted into a hospital. Being type 1 diabetic, makes everything 100 times worse. DO NOT USE F 23 100 days
50mg 1X day
5/18/2021
Email
 1  Anxiety Horrible dreams, sweating, felt like I drank 100 cups of coffee Talked to doctor and pharmacist and both said to just stop taking it since it's only been 2 weeks at 25mg. They both claim I should not have side effects. Wish me luck! F 48 14 days
25mg 1X day
1/27/2021
Email
 1  Anxiety Started pristiq at 50 mg on 11/13/20 . First 4 weeks very noticeable difference in anxiety (health) for the good. It worked, finally I feel normal I thought to myself. Well it was short lived, I noticed in the beginning I was tired, but that's to be expected on meds. Been on Zoloft it pooped out, lexapro od on 20 mg . But only med I'm on is prestiq . Lately past couple weeks it's all went downhill. I am so jittery , exhausted, my stomach and intestines hurt at times. shoulders, overall achy, it's almost a chore working all day. I get home and I'm so tired but can't sleep, have 2 kids and a wife that I don't even want to talk to or be around. And I love them so much, I'm emotional, rage for no reason. Jittery, and can't seem to sit still , just scroll through channels on the tv for hours . I do clean my house all the time, not sure if that is a bad thing but comes in part with not being able to sit still . Can't focus on anything, don't care attitude. It's a terrible drug. My body twitches for no reason, scared to drive and don't want to leave the house . Almost scared to. So dizzy , feels like there's a wall in front of my brain, blurry vision and chest tightness. Check my pulse ox and blood pressure 10 times a day Oh and the chills, can't seem to get warm. Some sweating episodes but mostly cold to the bone. Just a feel of dread , don't recommend. Please feel free to email me M 42 2 months
50 1X day
1/11/2021
Email
 1  Depression, Anxiety Brain fog, very slow reaction time, very dizzy, couldnt drive, couldnt think or make decisions, lactation and weightloss, no rem sleep, supressed my emotions, night sweats, memory loss, its like someone stuffed cottonwool in my head. I wasnt monitored on it. The doctor didnt make sure I was getting help from a therapist while taking it which should be mandatory. He even suggested I go out and drink like a normal 22 year old girl. You CAN NOT DRINK ON THIS DRUG! Worst years of my life. Also to get off it you have to spend a long time vomiting, sweating, shivering and feeling like your having a heart attack. Dont give this to young women! You might as well roofie them and send them out into the world. This is a really dangerous drug. Since being off it its like a curtain has lifted and I can think, work and my memory has come back. It also started wearing off after 4 years. F 28 7 years
100 1X day
11/9/2020
 1  Depression Cant get out of bed tired hurting as of sore 34 0 months
1X day
10/13/2020
Email
 1  Depression Unbearable side effects such as nausea, dizziness, headache and tinnitus. This drug should not be prescribed to any human on the face of the earth M 52 60 days
50
6/13/2020
 1  Depession Headaches...dry mouth...fatigue...constipation and stomach pain F 66 2 weeks
25 then 50
2/14/2020
 1  MDD, HAD, PTSD It was causing headaches, sexual dysfunction, zer9 appetite, increased heart rate, dry mouth, increased anxiety, irritability. It did help the depression slightly, but brought along a host of other issues I can't live with. F 47 30 days
25
12/29/2019
 1  Major depressive disorder Severe nausea, constipation, weight gain. I was extremely nauseated on Pristiq - so much so that my doctor had to prescribe me Zofran, which I took 1-2 times a day. I was waking up with severe nausea, so my doctor also prescribed Phenergan to be taken at night to try to combat the morning nausea. And Pristiq made me seriously constipated. I had to take a fiber supplement and stool softener daily. I was taking a total of 4 medications just to combat Pristiq's side effects. Also, Pristiq can decrease appetite and help people lose weight. It was the opposite for me. I gained 15 pounds in 3 months!! Pristiq did lift my mood some, but it was totally not worth all the side effects that came along with it. I'm now on a different antidepressant and trying to lose the weight I gained on Pristiq. F 40 3 months
50mg 1X day
9/3/2019
 1  Depression Extreme weakness to the point of feeling like I was gonna pass out. I couldn’t hold up to do much of anything. Also had dizziness & nausea, constipation, easily agitated and irritable. I’m going to see my dr next week about getting off of it but I’m concerned about the withdrawal symptoms. F 61 6 months
25
6/22/2019
  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

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