PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction highest to lowest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32


RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Depression I started at 25mg and saw improvement so stepped up to 50mg. I was jittery for about a week and a half after stepping up to 50mg, and got a little sleepy after taking it. Also had dryness in the back of my mouth, but that's gone away as well. The only other negative side effect is difficulty reaching orgasm, in fact it's nearly impossible; so still trying to figure out what to do about that. I read "alternative sex practices" may be a solution on a couple different websites, whatever that means. I honestly have to say this drug saved my life. I fought depression for years and started trying medications three years ago, they either did nothing or made everything worse. After my brother took his own life last year, I was at the end of the rope. I tried a couple more medications with no success and then I started the lower dose of pristiq about eight months after his suicide and noticed I felt better. After going up to 50mg, in a week the endless loop of negative thoughts vanished. My wife said to me, “It's good to finally have you back, I was starting to think you may be lost forever if something didn't change.” I really had no idea how deeply I had fallen until the fog lifted and I could look back at the hole I'd been in for years. The last side effect I listed is disappointing, but worth it considering I'd had pretty much zero interest in sex (or anything else for that matter) for over a year. It's all about finding a medication that is a good match for you; I didn't realize how much depression is an illness, not just an attitude or personality issue until I was finally out from under it. M 51 60 days
50 1X day
2/21/2022
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 5  Anxiety/ Depression None Different meds affect people differently. Pristiq is one that works very well for me, even at a low dose, with no side effects. I was only having mild symptoms, but started this again a few months ago. Thought I might not need it any more so weaned off it. I noticed a big difference in how I have been feeling without it. My mind goes around and around worrying about silly things. I am also too sarcastic in a mean way and can't stop myself from saying rude things. I feel cranky about minor things. I also started eating tons of carbs which I do sometimes when I'm feeling “ off”. I felt much calmer and at peace with a small dose of Pristiq, so I am just going on go back on it for now. It also helps a bit with my sleep which is always disrupted from a painful chronic condition. F 57 90 days
25mg 1X day
1/15/2022
 5  Depression/Anxiety Increased sweating, weight loss I live in Quebec Canada. The Covid-19 measures, confinement, curfew at 8 pm, stores and gyms closed made my life a living hell and I tried to kill myself twice. I lost 5 of my friends because they killed themselve because of that pandemic crisis. So I went into a deep depression but Pristiq saved my life. I am able to go back to work and live my life. The gym reopened so it helps. But I have to loose the 60 pounds I took since the pandemic started. I lost 20 lbs but still have to loose. My energy is back. M 41 3 months
100 mg 1X day
4/5/2021
 5  Depression, anxiety, PTSD, ADHD My side effects: laughing, enjoying life, love exercising, more social, feeling confident, no irritability, successful in life etc... I definitely would recommend to anyone struggling. No need to struggle and be miserable when you have Pristiq. Wish I would have known about this medication years ago. I have worked in healthcare/hospital for years and Pristiq has helped me tremendously to get through such horrific times. I am now able to take great care of COVID patients without feeling so overwhelmed, anxious and depressed when I thought I had nothing left in me... if you are struggling-Pristiq may be your life changer. Highly recommend. F 40 2 months
50 1X day
12/13/2020
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 5  Depression, anxiety Slight sexual side effects but nothing major. This medication has been a game changer! If you've tried SSRI's and haven't had success, I recommend trying Pristiq. I'm so glad my psychiatrist suggested it and that I was open to trying it. F 38 2 weeks
50 mg 1X day
12/9/2020
 5  PTSD mdd,ocd and anxiety None I love this it gives me hope and I'm so happy on it I dont cry or get upset I just have so much energy and I can think clear F 39 0 days
50 1X day
11/5/2020
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 5  Depression I was told to take it in the morning but it made me so sleepy in combination with other meds that also cause sleepiness so switched to night. End of problem. Slight headaches, slightly blurred vision, very dry mouth. Itchy skin which may or may not be related to the drug. I was prescribed this because the medication I take for bipolar wasnt enough for the down side. Effexor was ineffective entirely. Within a week I was feeling better. After 30 days I havent had a single bad episode of depression. The side effects are worth it to me. F 60 30 days
25 MG
10/23/2020
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 5  Depression, anxiety When attempting to switch to another antidepressant because of insurance reasons, I got extremely dizzy. This has been the best antidepressant I have ever been on, secondary to Prozac which sadly just stopped working. This has been the drug that works amazingly for my symptoms. F 44 3 years
100mg 1X day
8/23/2020
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 5  Depression and anxiety Nausea, motion sickness even while being the driver, shakes and sweats, feeling a bit too amped up, bruxism, dry mouth, constipation. I am obviously a new user to pristiq, having only been on it for 2 weeks, so take this with a grain of salt. I have a disease similar to lupus that causes so many symptoms that I may have had more side effects without knowing. This disease also makes me exceptionally sensitive to medication and I tend to get every rare side effect on the book (and it's no different with this one. I've gotten a few of the concerning side effects and my Dr and I are just monitoring it for now. I'm also extremely sensitive to serotonin and I and my brother have had serotonin syndrome several times, including any time we tried an ssri, so I was very nervous to try an snri. I take bupropion xl (300mg) Lorazepam (1-2mg) pristiq sustained release (25mg) phentermine (37.5mg) in the am and trazadone (200mg) seroquel (50mg) unisom (doxylamine, 50mg) omprazole (20mg) at night. I also take 800mg of ibuprofen 2 to 3 times a day. While I still worry about serotonin syndrome, as it's still building in my system, from the very first day the results were huge for me. I have severe clinical depression and generalized anxiety, social anxiety, and a panic disorder that has only just begun the last year of so. I feel good. Yeah I get a bit shaky, and sometimes I struggle to spit my words out, which I'm used to with my disease, but I can't describe it. The depression is always there, but it's like I'm hearing it knock through a 10" solid steel door. I hardly am even conscious of it. F 35 14 days
25mg 1X day
8/21/2020
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 5  Depression Anxiety Just have to take it same time every day. Just within a few hours of not taking my dose for the day I get side effects of headache, nausea, etc. Missing a whole day causes that next day of being very ill. Otherwise if take like clockwork it has been the best antidepressant ever. F 47 8 months
50 1X day
8/15/2020
 5  Schizoaffective, ocd, panic, anxiet None Helped my ocd and the depression part of my schizoaffective a lot, with less sexual side effects than my previous antidepressant, which is primarily why I switched. I am able to enjoy sex again. I did quickly have to go to 100mg for it to work well for me. After about a year on it though my depression is beginning to come back so I am actually switching to another antidepressant that is supposed to be more effective for my eating disorder. F 31 1 years
100
6/12/2020
 5  Dysthymia/Anxiety/fibromyalgia First month: 10 lbs weight loss, decreased appetite, insomnia, anxiety, euphoria, stimulation, elation, increased sweating, hyperhidrosis. After one month: none except increaesed sweating. Really effective for treatment-resistant depression, dysthymia, social anxiety, panic disorder. I tried so many antidepressants and it was the first one that really worked beside Anafranil (tricyclic AD). Anafranil was the best one, but the sides effects were to intense for me. Pristiq help me to be more stable, more sociable, increase my energy and concentration cause I also have ADHD. A bonus is that it makes my muscle pain almost disappeared and I'm able to go to the gym 6 times per week. My life is worth living since I take prsitiq and after just 5 days at 100 mg, I was depression free and happy again. It does'nt affect my libido like SSRI's and Anafranil. So briefly, I have so much more motivation and pleasure. I also take Wellbutrin XL 300 mg, cytomel 15 mcg, Lamictal 200 mg, Adderall XR 40 mg and zopiclone for sleep. Finally, Pristiq is better than, Prozac, Zoloft, Paxil, Celexa, Lexapro, Abilify, Luvox, Seroquel, Elavil, Trazodone, Seroquel, Latuda, but everybody is different. It works for me, and dont listen to people that say dont take it, and blame the drug for their bad decisions like forgetting to take it everyday at the same time and complaint about the withdrawal. If you are not responsible, blame everything but yourself, dont go for therapy and dont change your negative thinking or bad habits and behavior, you will never find happiness and peace. It might work for you, but like I said, it depend on your brain biochemistry. M 40 1 years
100 mg 1X day
6/8/2019
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 5  CPTSD/Depression None Pristiq has saved my life. F 42 1 months
50 2X day
12/20/2018
 5  Anxiety/Mild Depression I've had a very interesting and unexpected side effect from taking Pristiq. Having taken Pristiq last year for several months and then going off due to co pay costs being so high at the time, I switched to Effexor (wasn't as helpful as Pristiq was for me) so recently, the cost of Prestiq went way down and I knew I wanted to switch back to it - I was positive if this was a side effect of Pristiq last year when I took the medication, but I feel very confidant saying I believe it was because when I stopped taking it I noticed it stopped, but when I started taking Prestiq again it came back ... I don't quite understand how or why, but I believe that not only does it help me, doesn't make me gain weight and has minimal to no negative side effects, the most interesting things I observed while taking Pristiq is that I have much longer and more intense oragasms with my husband. I feel funny sharing this, but it's 100% true! I've always had a good and healthy sex life with my husband, except I have taken medications in the past that I thought slowed my libido down a little so I stopped them - but not only does Prestiq not interfere with my sex drive, I really believe for some reason, some way, some how it absolutely has improved sexual satisfication and oragams. I truly wonder if this has effected of women in a similar way, because of so this could be the start to like a mild version of Viagra, but for women! How amazing would that be for all the women our there who feel they're sex d Love!!! Truly helpful! F 32 60 days
50
4/29/2018
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 5  Depression Minor sweating first 3 nights, lower libido This is the best drug I've tried, and I've tried most SSRI's, Wellbutrin, and Trintillex. The feeling of 'dread' is much lower, and my head feels calmer. Virtually no side effects. There is a lower libido, but I've experienced that with all drugs, except for Wellbutrin, which was not very effective M 42 30 days
100 1X day
12/12/2017
 5  Depression/Social anxiety/ADHD None Pristiq is a real miracle drug. The best so far. I tried all of them almost, including TCAs, SSRIs, Brintellix, Effexor XR, Cymbalta, Seroquel, Abilify. TCAs are more effective fore treatment resistant depression, but have a lot of side effects. SSRIs are useless for me, Effexor not bad, but weight gain and fatigue, Seroquel by far the worst. With Pristiq my depression and anxiety disappeared in less than 1 week. First 3 days I was on 50 mg, but thought that it was almost a placebo, because normally antidepressants have a lot of side effects so I increased to 100 MG and after 3 days, wow! I have so much more energy and motivation, more outgoing, more positive, way more productive, not lazy anymore. The only thing I'm not super happy with, is my libido is sky high, and I'm horny all the time. At least, my orgasms are more intense and more pleasurable. I lost a little bit of weight (10 pounds), but I feel more self confidant and more attractive. I have more motivation to go to the gym and stay in shape. I feel better than ever. Don't listen to the negative reviews that may stop you from feeling better and get out of the hole I was in for 10 years. M 38 2 months
100 MG 1X day
5/20/2017
Email
 5  Depression and anxiety I felt very nauseous for the first few days after taking it but have had no side affects since and have been taking for years. This drug enables me to function properly - I lost a small part of my creativity but before this drug could not concentrate or follow through with any plans. I am far more productive than I was before and it has also made me worry less about silly things and my relationships have improved as a result. I was lucky it worked well for me but all drugs don't work for everyone unfortunately. It's worth a go.. but switch to something else if it's not doing you any favours. F 28 3 years
100mg
2/18/2017
 5  Clinical depression and anxiety Initially I had night sweats but once I got used to taking them I was fine. If I ever miss a dose I feel very weak and nauseous. Otherwise this is the best antidepressant I've ever been on and I'm doing better than I ever have. F 25 1 years
200mg
2/6/2017
 5  Depression and anxiety First couple wks was forgetful and was hard to come up with words I wanted to say I was on Paxil for about three years then tried Effexor and now Pristiq! Pristiq has helped me be so much more confident, where I can actually speak in front of a group of people. Everyone reacts differently to medication. I hope this helps:) F 26 6 months
100 mg
11/5/2016
 5  Depression Occasionally I will feel disconnected and have a lower libido, but this is tolerable. I've had really bad side effects with other anti-depressants so I'm very satisfied. I immediately started to feel less depressed, more motivated, and an increased (healthy) appetite. F 20 8 months
50 mg 1X day
10/31/2016
  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

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