PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender males first.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32


RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Depression Yawning, Delayed Ejaculation, Loss of Libido Working great and effects kicked in from day 1. I'm still amazed just how much it has changed me, going from moderate/severe depression into a place where I feel inner calm. I can't thank the drug manufacturer enough. While I do have side effects I can live with them as long as it continues to make me feel happy. It's just such a big relief not to feel crap all the time. M 27 2 weeks
100 1X day
2/16/2010
 5  Anxiety I switched from Effexor to Pristiq because I was experiencing extreme intense headaches - they were almost unbearable! Since the switch, the headaches are gone! I do however experience slight irritability and a slight loss of libido. I experienced these on Effexor too, but they seem better since the switch :) I feel reeeeeally good! I take Pristiq for anxiety - although it has not helped 100% with the symptoms, it has helped me a great deal - it has given me lots of confidence and motivation which I lacked before. I don't have depression, but I have noticed that I am HEAPS happier too! I think it's probably due to the confidence etc boost :) yay! P.S. It's a good feeling to feel like this after trying SEVEN difference types of meds! So a little advice: hang in there! :) M 25 2 months
50 1X day
9/3/2010
 5  Chronic Pain and Depression irritable, tingly, impotence, mood swings, mania, The side effects faded over time are all largely minimal. Pain has been reduced and depression faded away. I blogged about it extensively if anyone is interested. http://www.alifelesspainful.com/2011/02/pristiq-my-experience-summarized.html M 47 2 months
50 MG 1X day
2/3/2011
Email
 5  depression I have depression, induced by an unpleasant divorce and have been taking Pristiq (50mg) for 6 weeks. First 3-4 days made me feel drowsy, but no other side effects. Positive effects were noticed after about 4 weeks, particularly in work which had become a big problem. Lethargy, lack of interest and concentration have all improved a lot. Outside of work, appetite has improved and sleep patterns are starting to improve M 51 6 weeks
50mg 1X day
1/19/2012
 5  MDD with Seroquel and Lamictal None at all It seems to me that SSRI's are old school and SNRI's are new school. You owe it to yourself to see what effect noriepinephrine reuptake has on your brain. It has made me a new man!! M 36 600 days
50 1X day
1/10/2012
Email
 5  Depression/Anxiety None. I have had severe headaches and dizziness for several months. I had been suffering from depression and anxiety when I noticed these symptoms. My doctor prescribed Pristiq and my headaches are gone. Been a life saver. M 44 8 days
50MG 1X day
12/31/2012
 5  Depression/OCD Sharper vision, thoughts better organized, little to NO effect on libido, increased energy, helps depression perfectly with no hypomania, sedation, or spaced out feeling like other antidepressants. Changed from Effexor XR 150mg to Pristiq 50 mg. Minimal withdrawal, side effects MUCH less pronounced. Very clean feeling from this SNRI M 27 2 weeks
11/2/2008
 5  anxiety.. tiredness, last an hour in the bed(sexual)wear-out my wife, lol , but nothing major! Low dose of effexor has worked for me in the past..but this has a different "feel".. But seems to be effective..havent been on it for very long! M 42 5 days
3/2/2009
 5  Severe depression & anxiety During first few weeks, and with insufficient dosage (50 mg), same odd flashes as on Effexor XR when dose is overdue. After that, very few effects attributable to the med. With sufficient dosage (100 mg) and sufficient time to acclimate, Pristiq is as good as Effexor XR ever was, but has very little in the way of tangible side effects. I am very even-tempered, but do not feel numbed-out emotionally or physically. Energy level is pretty good, mind reasonably clear for a guy entering early geezerhood. I was on the minimum dose for Effexor XR, so my Dr. initially put me on 50 mg Pristiq. This did not work. Upon reporting this to her, she put me on 100 mg Pristiq. First 10 days were NOT a lot of fun, then everything smoothed out. A word regarding soem of the previous responses here: You cannot judge ANYTHING about an SSRI or SNRI in a few days. Unless your are experiencing extreme anguish that is different from how you previously felt, or you have some kind of new life-threatening physical symptoms, give the drug a chance! It really does take quite a few weeks before your brain chemistry settles into a new stable pattern. I know very well that patience in the face of severe depression is very difficult, but please try to muster it up, and give timely and accurate feedback to your doctor. M 66 3 months
3/25/2009
 5  Anti-Depressant Mainly sexual but the wife and I are working through it. Began to see small results the first day. After the 3rd day I felt like my old self. I am happier than I ever have been and has actually helped to calm my ADD. The other item I notice is that I am now a little more "hotter-natured" than I was previously, but do not have any sweating. I just keep the office cool. I have heard of others that have had a hard time going through the initial month, but after that I've heard nothing but good things. I really feel the best that I have in my whole life. My negativity is gone and I now see positives in everything. My Dr. advised me that it could take as long as two months before everything is regulated. Thankfully, it didn't take that long for me. M 41 2 months
8/11/2008
 5  OCD and anxiety None No sexual problems when using this SNRI. M 45 7 days
8/25/2008
 5  Anxiety, ADHD Paraesthesia, insomnia (take it at night, my advice), dulling of the senses, lowered appetite [which i like], inability to recall words, increased tremor as elicited by anxiety, onset of panic attacks quelled by alprazolam. Extreme difficulty in concentration and by third week, a VERY strong feeling of dysphoria and lack of motivation, none of which i EVER had before in my life. Very original. An antidepressant that made me depressed when formerly I had never been depressed. A supposedly effective cure for ADHD according to my doctor who should really retire by now because he's starting to forget his name...which made me have ADHD times 10. And anxiety increased with time and dose, and best of all, a nice healthy tremor to top it off. M 25 7 weeks
4/15/2009
 5  depression sleepiness (so I take it in the evening); slight decrease in sexual sensitivity (but not bad enough to discontinue the drug); slight urinary retention Had I rated this drug a few weeks ago, I would have given it a 2. It does seem that the antidepressants take a good month to reach effectiveness. Also, I was surprised to find a serotonin reuptake inhibitor for me with negligible sexual side effects. Pristiq makes it easier for me to regulate my emotions. M 36 5 weeks
4/29/2009
 5  Depression occasionally irritable. I was very skeptical about trying PRISTIQ because of all the negative comments about it being an "effexor retread". My experience has been that PRISTIQ is superior to effexor, in terms of side effects, and antidepressant effects. Specifically sexual side effects are minimal, and weight gain has been no issue. M 58 6 months
7/17/2009
 5  Bipolar Depression, GAD Headache, mild nausea, and mild sexual side effects-All in the first week. Since that first week they have passed and the only side effect I have is complete relief of Depression. It has been a miracle for me. Tried everything in the book to combat my severe lows of Bipolar II. Finally my psych gave me some samples for this stuff. I was doubtful as I had tried Effexor previously to no avail. After 6 days on Pristiq I woke up feeling like a had some years ago. I am glad to say I am now in remission. M 19 15 days
8/13/2009
 5  Depression, anxiety, FM, PMDD In the first 2 weeks, major night sweats, diarrhea, emotional lability, headache I am now beginning my fourth week on Pristiq 100 mg after switching from Cymbalta 120mg, which I had been on for 4 months. I was nearly out of my mind with anxiety and depression with Cymbalta, and also felt like I had a bad flu for four months with it....not good!! I can honestly say that I feel almost comletely restored to my former vibrant self with Pristiq. It's just amazing how some medications work wonders for some and do nothing for others. Cymbalta was my "drug from hell" and Pristiq is "from heaven". The depth of my gratitude that this drug is avaialble to those who know the excruciating suffering of these terrible illnesses... thank you Pristiq. I will report back if there are any changes! For those of you who haven't found the right med yet, keep trying, and try to persevere through the side effects for at least a month before you give up. My headaches, diarrhea, mood swings ALL GONE. No sexual side effects at all, in fact, my libido is great! I still sweat a lot but I figure that's nothing to put up with in exchange for peace and good quality of life. M 42 1 months
9/27/2009
 5  Chronic Major Depression Decreased Libido I'm taking Pristiq 50mg, Wellbutrin XL 300mg, & Abilify 15mg. This combination is helping me to feel like normal again. Pristiq is as good or better than Effexor XR with fewer side effects. If you're just starting, give it a chance. It's worth it. M 49 1 years
10/10/2009
 5  depression/anxiety/mood swings First 3 days, i experienced , euphoria, sleepless nights, palpitations, upset stomach, blurred vision, after that, everything gradually went away, and besides some muscle soreness every now and then, this drug has pretty much turned things around for me in a very good way! M 42 14 days
11/4/2009
 5  Depression Minor sweating first 3 nights, lower libido This is the best drug I've tried, and I've tried most SSRI's, Wellbutrin, and Trintillex. The feeling of 'dread' is much lower, and my head feels calmer. Virtually no side effects. There is a lower libido, but I've experienced that with all drugs, except for Wellbutrin, which was not very effective M 42 30 days
100 1X day
12/12/2017
 5  Depression Best med out there in my opinion. Tried celexa, wellbutrin, and viibryd. Little to no side effects with Pristiq. Gives motivation and drive to push forward and look toward a productive future. Would really recommend this medication. M 38 1 years
50
1/10/2015
  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

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