PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age oldest to youngest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Depression Extremely terrifying nightmares, REM Behavior Disorder, cannot get out of the dream for some time after coming out of deep REM sleep, exhaustion, insomnia, dizziness, fuzzy vision, etc, etc,, CAUTION warning for elderly NOT shown on sample package provided me by prescribing physician. Only found out about risks to elderly when terrible side effects prompted me to go to my pharmacy where I usualyy go and request a copy of their Patient Information sheet where Caution Warning for the elderly printed thereon in CAPITALS. M 86 4 months
50 mg 1X day
7/6/2010
 4  Clinical depression Constant heartburn Came off it for a few days and withdrawal symptoms were terrible F 74 10 years
100 MG 1X day
11/29/2020
Email
 4  Depression, Anxiety Weight loss I have tried many antidepressants over 28 years, and Pristiq is among the most effective for me. No matter what I take, however, I still experience some depression and anxiety; it is likely that no medication will completely eliminate my symptoms. Pristiq does allow me to function relatively normally, and I am grateful for that. I do supplement Pristiq with Seroquel (quetiapine) 25 mg for sleep. Otherwise I would have extreme difficulty falling asleep. I have experienced very low libido over many years, and Pristiq does not seem to have affected this one way or the other. F 72 2 years
100 mg 1X day
6/4/2015
 4  depression Reduced libido When I am on this drug, I feel great, and occasionally I even skip a day, but if I skip more than a day, I spiral down almost immediately. This drug has worked wonders for me. I consider it much better than Paxil, which really zonked me out. M 69 6 years
50 1X day
2/22/2017
 3  anxiety/depression the usual trembling of the hands-otherwise none- but see below switched from Prozac- better feeling affect- tears-laughing etc. took in am-it did seem to fade later in the day. However, both times i missed a dose-had frightening/disturbing nightmares- seriously considering going off. M 68 5 months
50 1X day
10/18/2010
 3  depression Lost 20 pounds just like that. Does absolutely nothing for OCD. I actually had my DNA done by a company that promised to find my ideal antidepressant. The service cost $350, but my insurance paid for it. I switched from a long-term scrip of EffexorXR. I dropped 20 pounds in days--have enjoyed the smaller body and weight loss tremendously. However, whatever control EffexorXR had over my OCD is completely gone with Pristiq. My moods are terrific--no big swings or drops. The OCD, though, has come back in a huge way. I have always been a clock fan--now I have dozens. They were joined by lamps and shades in the spring--filled the garage with them. I discovered "upcycling" old clothing--and like that, the lamps could go. The Habitat Store was delighted. I have been searching for the "right" ceiling fan--this search has become so burdensome, I was actually considering going back on Effexor. Pristiq is a higher-tier med than my insurance wanted to pay for, but I spoke with them directly and got it covered--due to that DNA study. My depression and anxiety issues would be "solved" if not for the ones generated by my obsessions with lamps, clocks, and fans. Even when I know it's "wrong," I find myself bringing home something I sure don't need. F 68 2 years
50mg 1X day
10/3/2023
 2  panic attacks, major depressive d/o urinary incontinence, feeling of deja vu @ times, memory & word retrieval problems, night sweats, racing thoughts, depression worse, bizarre dreams. Weaning off this drug! After all comments I am dreading w/d symptoms but I must get off this drug!!! Am going to get genetically tested to see ssri or snri that may work or maybe atypical med. I'm taking 350mg Bupropion already. F 68 2 months
150mg 1X day
10/17/2019
 2  Prescribed by PCP for Panic Attacks I am an Analyst of Everything, but I could NOT do my job as a professional IT consultant and I had to prep for a job in less than two weeks. My MD weaned me off of Pristiq using a plan I developed. I believe Pristiq may be great if you are depressed. However, it should NOT be taken for Panic Attacks. It is much too strong! And that's my professional opinion. Contact Tom for more information - [email protected] M 68 11 days
7/29/2017
Email
 4  Chronic depression Only side effects for me were constipation and difficulty sleeping. Changed diet and added Trazadone for sleep I have had chronic depression for years ( 25 at least ). Started on Prozac, went to Lexapro, then others that I can't remember their names. I was put on Pristiq when it first came out. I started with 100MG then down to 50 MG. BEST drug for me. I am now 67 and have weaned myself off the drug completely. Now that was a real challenge! F 67
50 MG 1X day
6/20/2015
Email
 3  Depression/anxiety Lost 20 pounds; feel terrific till I don't. I was on EffexorXR since it came out as an XR. No major complaints--but, then I saw a poster in my doctor's office about having my DNA done to find out the best antidepressant for me. Turned out Pristiq was better for me--and after duking it out with my insurance company, they cover it. It seemed perfect--until I became hopelessly hooked on Pinterest--lamps and lighting...? I do have diagnosed OCD--apparently, Pristiq does nothing for that. Not sure if it actually exacerbates it--but I am completely unhinged about our decor, our lamps, our ceiling lights--I've even lost hours of sleep over needing a Lava Lamp--or looking up how to make one at home for nothing. My personal relationships are wonky, too. A friend with a lot of problems of her own became my project and I don't even like being with her--but I did more for her than I've done for just about anybody in my life. Then, she told me she didn't have time to be the friend I need right now--I have relived that moment and that text a million times--the sleep I've lost! Seems the only time I'm not thinking about this slight is when I am thinking about how to make the perfect coolie lampshade. No--that's not racist; it's a style. I can't say I'm depressed--just exhausted. I've got lampshades down though... F 67 1 years
25 1X day
10/2/2022
Email
 2  Depression Only on day 3 and at the same time withdrawing from Remeron Sol-Tab. The first 2 nights slept 2 hours per night Also suffering nausea, heartburn, loss of appetite,.. Doctor prescribed this after a relapse following 5 years depression-free. Am taking it first thing in a.m. Am determined to stick with it for a month and will report back after that time. Insomnia might be caused by Remeron withdrawal as I depended on it to get me to sleep. But thus far altogether unpleasant. F 67 3 days
50 mg 1X day
6/11/2010
 5  Severe depression & anxiety During first few weeks, and with insufficient dosage (50 mg), same odd flashes as on Effexor XR when dose is overdue. After that, very few effects attributable to the med. With sufficient dosage (100 mg) and sufficient time to acclimate, Pristiq is as good as Effexor XR ever was, but has very little in the way of tangible side effects. I am very even-tempered, but do not feel numbed-out emotionally or physically. Energy level is pretty good, mind reasonably clear for a guy entering early geezerhood. I was on the minimum dose for Effexor XR, so my Dr. initially put me on 50 mg Pristiq. This did not work. Upon reporting this to her, she put me on 100 mg Pristiq. First 10 days were NOT a lot of fun, then everything smoothed out. A word regarding soem of the previous responses here: You cannot judge ANYTHING about an SSRI or SNRI in a few days. Unless your are experiencing extreme anguish that is different from how you previously felt, or you have some kind of new life-threatening physical symptoms, give the drug a chance! It really does take quite a few weeks before your brain chemistry settles into a new stable pattern. I know very well that patience in the face of severe depression is very difficult, but please try to muster it up, and give timely and accurate feedback to your doctor. M 66 3 months
3/25/2009
 1  Depession Headaches...dry mouth...fatigue...constipation and stomach pain F 66 2 weeks
25 then 50
2/14/2020
 2  anxiety,depression,ocd slight headache,upset stomach(mild) have been on med a little over 2 months. not as extremely depressed however still anxious and frustrated with moderate to high depression. doctor has just added abilify to speed up effectiveness. hope it works. M 65 10 weeks
12/15/2008
Email
 2  GAD- General Anxiety Disorder a little dizzy when getting to standing position, gas, constipation. More major side effects is waking after several hours, and sexual dysfunction(Anorgasmia) M 65 8 days
11/19/2009
Email
 2  depression Shakiness and tremor. Handwriting looked like a 90-year old stroke victim. I reduced it to 50 (on my own) and my handwriting is almost normal. I really don't think this has done anything for my depression. Really don't think this has done anything positive for my depression. F 65 3 months
100 mg. 1X day
2/20/2010
 1  depression, Brain zaps, anxiety, tremors, insomnia, felt horrible! Had been on 150 mg of venlafaxine for several years, but began having crying jags and insomnia. So Dr. changed me to Pristiq. Started feeling horrible the first day! Brain zaps and dizziness, blurred vision, night terrors, sweating, tremors, insomnia, headach. You name it I had it! It was the most horrible experience of my life! Could not tell if symptoms were caused by Pristic or from with drawal from Venlafaxine. Went back to my Dr. after 5 days and he told me THERE WERE NO WITHDRAWAL EFFECTS TO EITHER DRUG! Also that I should not have side effects to Pristic if I had tolerated venlafaxine. WTF!!! I know how horrible I felt, so either I am totally nuts or I need to change Doctors! I am now off both drugs and I feel fine! F 65 5 days
50 1X day
6/13/2010
 5  severe depression and anxiety none Have been on Pristiq for one year now. First 50 mg, now 100 mg. Best antidepressant ever been on - have been Rx'd most of the common ones over 20 years. On Pristiq I do not get to the bottom of my depression and don't cry all the time. Feel like problems are still present, but am able to deal with them better now. Example: suffer from lonliness but am better able to cope with being with myself alone and more interest in other things. don't dwell on it so much anymore. Love Pristiq!!! F 64 12 months
10/29/2009
 1  Panic Attacks First, erectile dysfunction & delayed ejaculation; then, numbness in both feet went to ER; it was withdrawal symptoms or what Pristiq calls “Discontinution Symptoms” ). Then, had insomnia that night, as well as, unintended, “multiple orgasms” w/o ejaculation. Felt like brain was being “rewired”. Felt tingling at nerve endings, and had an acute headache in the upper, left, back portion of brain. Contact me if you want MY18 DAY PLAN my M.D. to wean me off of Pristiq ..... FREE! [email protected] DO NOT TAKE FOR PANIC ATTACKS! Especially, if you are any type of Analyst of Everything (or anything); or need your brain to be able to analyze data, facts, etc. M 64 10 days
50 mg 1X day
2/15/2016
Email
 1  Depression and anxiety Jaw pain anxiety headaches insomnia F 64 2 years
50mg 1X day
1/18/2022
Email
  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

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