PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  depression Lost 20 pounds just like that. Does absolutely nothing for OCD. I actually had my DNA done by a company that promised to find my ideal antidepressant. The service cost $350, but my insurance paid for it. I switched from a long-term scrip of EffexorXR. I dropped 20 pounds in days--have enjoyed the smaller body and weight loss tremendously. However, whatever control EffexorXR had over my OCD is completely gone with Pristiq. My moods are terrific--no big swings or drops. The OCD, though, has come back in a huge way. I have always been a clock fan--now I have dozens. They were joined by lamps and shades in the spring--filled the garage with them. I discovered "upcycling" old clothing--and like that, the lamps could go. The Habitat Store was delighted. I have been searching for the "right" ceiling fan--this search has become so burdensome, I was actually considering going back on Effexor. Pristiq is a higher-tier med than my insurance wanted to pay for, but I spoke with them directly and got it covered--due to that DNA study. My depression and anxiety issues would be "solved" if not for the ones generated by my obsessions with lamps, clocks, and fans. Even when I know it's "wrong," I find myself bringing home something I sure don't need. F 68 2 years
50mg 1X day
10/3/2023
 1  Deprssion I WOULD NEVER RECOMMEND! Would give -1000 if I could. After taking it for 4 ish years ( now off ) I have long term hyponatremia ( low sodium). I have been hospitalised for it and have been told I need to restrict my water intake going forward potentially for the rest of my life. The side effects were painful also brain zaps insomnia and the worst anxiety I have ever experienced. AVOID!! F 35 4 years
50 1X day
9/23/2023
 1  Depression Going on this drug was the worst decision ever. They warn of potential low sodium levels however since I have been off this drug it has continued. To the point I had to be hospitalised for low sodium and have been told I will need to restrict my water intake moving forward. I never had any problems with my sodium levels prior. I also had a terrible time coming off it really bad brain zaps, anxiety, insomnia. F 35 5 years
50 1X day
9/23/2023
 2  Anxiety Anxiety, weight gain, high blood pressure This Medicine was amazing at first and helped with my panic attacks but after 15 years it’s made them worse and completely stopped working. I have gained 25 lbs being on this medication and now have to be on high blood pressure meds F 40 15 years
100 1X day
1/16/2023
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 1  Anxiety, depression Migraines, left side of neck pain/stiffness to the point of just wanting to lay down, sleepiness, burning eyes, ringing ears, can't orgasm, stomach pain, random muscle pain throughout body, irritable, insomnia. Id rather just be depressed and anxious. M 38 7 days
50 1X day
12/27/2022
 1  Anxiety Tremor, heart palpitations, increased anxiety, extreme emotional lability, restless energy, anger. After stopping the medication: numbness in random extremities, electric shock sensations, nausea, sharp tension headaches Made me hypomanic, was sent to the hospital, still feeling withdrawl symptoms a week later. Caused me to lose my entire personality and my livelihood for weeks F 19 45 days
50 1X day
11/8/2022
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 3  Depression/anxiety Lost 20 pounds; feel terrific till I don't. I was on EffexorXR since it came out as an XR. No major complaints--but, then I saw a poster in my doctor's office about having my DNA done to find out the best antidepressant for me. Turned out Pristiq was better for me--and after duking it out with my insurance company, they cover it. It seemed perfect--until I became hopelessly hooked on Pinterest--lamps and lighting...? I do have diagnosed OCD--apparently, Pristiq does nothing for that. Not sure if it actually exacerbates it--but I am completely unhinged about our decor, our lamps, our ceiling lights--I've even lost hours of sleep over needing a Lava Lamp--or looking up how to make one at home for nothing. My personal relationships are wonky, too. A friend with a lot of problems of her own became my project and I don't even like being with her--but I did more for her than I've done for just about anybody in my life. Then, she told me she didn't have time to be the friend I need right now--I have relived that moment and that text a million times--the sleep I've lost! Seems the only time I'm not thinking about this slight is when I am thinking about how to make the perfect coolie lampshade. No--that's not racist; it's a style. I can't say I'm depressed--just exhausted. I've got lampshades down though... F 67 1 years
25 1X day
10/2/2022
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 1  Major depression Insomnia, cold sweats No help at all M 54 28 days
100 MG 1X day
9/21/2022
 3  Depression None yet F 44 1 days
50
7/9/2022
 1  Depression Worst discontinuation symptoms of any medication I've ever tried. Pure hell. Did not alleviate depression or pain. I regret ever taking this. M 50
1X day
6/22/2022
 1  Anxiety Insomnia, lost weight, lost appetite, depression, anger, self-harm, suicidal thoughts. I have paradoxical reactions like 5% of ADHD patients. So downers bring me up. And uppers calm me down. M 34 15 days
50 MG
6/21/2022
 3  Depression If I miss a dose, I feel completely hopeless. It is the closest I've ever came to suicide. If I miss a dose, I feel completely hopeless. It is the closest I've ever came to suicide. F 54 6 years
50 mg 1X day
3/23/2022
 1  Depression At first, I didn't realize it was the drug. My depression became worse and worse, and my doctor just upped it and upped it. I was unable to experience normal joy and enjoyment in life. I lost interest in everything. I had major mood swings and was far more unstable than I have ever been in my life. Prior to starting this, I was depressed for good reason due to situational trauma. After taking this, I was depressed by everything and for no reason at all. I could not get out of bed. I went to bed at 6:00 PM. I would lay around a lot. I couldn't muster the energy to clean, take care of daily tasks, take a shower, brush my hair, or exercise. I gained weight. I was hopeless and felt like dying. I went off and had horrific withdrawals to where I felt like life had no meaning and I wanted to die. However, once that passed, I feel much better. I have major stresses and grief in my life, situational traumas, and yet I feel better than I did when nothing happened and I was just on this horribl If I stayed on this, I would be dead. F 32 2 years
250 1X day
3/3/2022
 5  Depression I started at 25mg and saw improvement so stepped up to 50mg. I was jittery for about a week and a half after stepping up to 50mg, and got a little sleepy after taking it. Also had dryness in the back of my mouth, but that's gone away as well. The only other negative side effect is difficulty reaching orgasm, in fact it's nearly impossible; so still trying to figure out what to do about that. I read "alternative sex practices" may be a solution on a couple different websites, whatever that means. I honestly have to say this drug saved my life. I fought depression for years and started trying medications three years ago, they either did nothing or made everything worse. After my brother took his own life last year, I was at the end of the rope. I tried a couple more medications with no success and then I started the lower dose of pristiq about eight months after his suicide and noticed I felt better. After going up to 50mg, in a week the endless loop of negative thoughts vanished. My wife said to me, “It's good to finally have you back, I was starting to think you may be lost forever if something didn't change.” I really had no idea how deeply I had fallen until the fog lifted and I could look back at the hole I'd been in for years. The last side effect I listed is disappointing, but worth it considering I'd had pretty much zero interest in sex (or anything else for that matter) for over a year. It's all about finding a medication that is a good match for you; I didn't realize how much depression is an illness, not just an attitude or personality issue until I was finally out from under it. M 51 60 days
50 1X day
2/21/2022
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 1  Depression and anxiety Jaw pain anxiety headaches insomnia F 64 2 years
50mg 1X day
1/18/2022
Email
 5  Anxiety/ Depression None Different meds affect people differently. Pristiq is one that works very well for me, even at a low dose, with no side effects. I was only having mild symptoms, but started this again a few months ago. Thought I might not need it any more so weaned off it. I noticed a big difference in how I have been feeling without it. My mind goes around and around worrying about silly things. I am also too sarcastic in a mean way and can't stop myself from saying rude things. I feel cranky about minor things. I also started eating tons of carbs which I do sometimes when I'm feeling “ off”. I felt much calmer and at peace with a small dose of Pristiq, so I am just going on go back on it for now. It also helps a bit with my sleep which is always disrupted from a painful chronic condition. F 57 90 days
25mg 1X day
1/15/2022
 3  Depression and anxiety Taste impairment, raised blood pressure, occasional headaches M 38 8 months
50mg 1X day
12/29/2021
 3  Depression and anxiety Brain fog, jittery, insomnia first night I was on pristiq along with lexapro and wellbutrin from 2019-2020, and then stopped all three cold turkey June 2020. Strangely, I had no withdrawal symptoms. I don't recall having any side effects from the Pristiq the first time I started it. i wanted to go back on something I was already on, and so my doctor prescribed me Pristiq. First night I had insomnia, but it's gotten better. I have some brain fog and feel jittery, just off mentally, but I feel my mood is better. The side effects could go away, and what I am feeling may not even be related to being on pristiq. M 40 3 days
50 MG 1X day
11/19/2021
 4  Depression/anxiety symptoms Really not much serious. The doctor did raise my high blood pressure medication because Pristiq raised it. Maybe some anxiety the first few weeks but then that stopped and I actually feel that Pristiq helps my anxiety long-term. I have chronic fatigue due to atypical depression. I am tired a lot, have somatic pain, and apathy. I've found that Pristiq is great for energy. Actually I discovered that because, if I miss a dose or two, I become very drowsy. I just can't get out of bed. Then I take the Pristiq and within 4 hours I feel brand-new! So I guess I'm kind of stuck taking this drug now LOL. I tried to use fluoxetine (Prozac) to ease myself off of the Pristiq, but the withdrawal and fatigue are just terrible. I'm going to stay taking the Pristiq. M 38 6 months
100 mg
7/21/2021
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 2  Depression/anxiety Tired, no motivation, feel like I could cry at a moments notice. Libido is fine. No apetite. Dreams are vivid but not nightmares. Still going to continue on this to see if it levels out but by week 4 this isnt great. Weened off anxiety meds in the process so that could be the cause. Will wait and see.... M 42 4 weeks
50 1X day
6/25/2021
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PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

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