ZETIA Reviews (EZETIMIBE)

Average Rating: 1.4 (601 Ratings)

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 HYPERLIPIDEMIA

 Type: Rx Drug

  

ZETIA  (EZETIMIBE):  Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. Ezetimibe may be used alone or with other drugs (such as "statins" or fibrates). Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet. Reducing cholesterol may help prevent strokes and heart attacks.   FDA Approval Date: 2002-10-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age oldest to youngest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZETIACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  It was prescribed but I said 'no'. That is what I came here to learn. This is not a rating but I beg for a chance to say thanks to all of you for your comments. It justifies my decision to avoid Zetia. My new doctor prescribed Zetia. As always, I read about Zetia and you all know what I've learned. I am 90 years old and in excellent health. My cholesterol is a little high but not overly. I simply ran into a doctor who evidently believes in pill-popping. I do not. I avoid medications as much as possible. Since I have reached age 90-plus, I must be doing something right. F 90 0 days
8/29/2009
 1  high cholesterol Side effect: polymyalgia rheumatica (PR). Been suffering from PR for 14 years as there is no cure. F 85 14 days
30 1X day
6/14/2018
 1  to lower cholesterol Abdominal pain, tightness of chest, back pain, ankle and wrist pain. nausea. I am alergic to statin based drugs. I have been hospitalized from taking them. My physician prescribed Zetia to lower my cholesteral so I agreed to take it. The side effects from this drug is very scary. I thought I was having a heart attack. I am hoping I can overcome the side effects with time. M 84 12 days
10 mg 1X day
6/10/2012
 1  to lower cholesterol Cramping and aching in left leg, spreading at times to back muscles; weakness and varying pain in leg, reduced mobility, loss of appetite. With doctor's permission, I stopped taking Zetia after one month, and am hoping for symptoms to recede. Now taking Red rice yeast, flax seed, cinnamon, OneAday-Plus-Cholesterol. No tests yet. (I have been on vegan diet for 20 years.) F 83 34 days
1/24/2007
 1  borderline increased cholesterol Noted sore muscles, repetitive jerking motions of arms and legs while lying in bed, awakened me from sleep. Had only sore muscles for the first 2-3 years I took Zetia. Stopped Zetia after episode of involuntary limb movement. No recurrance in the last 1.5 years after discontinuing Zetia. Had been taking also 10 mng of Lipitor without apparent difficulty during this time. F 83 2.5 years
6/17/2007
 1  Lower LDL Severe aches all over. Could not sit down as buttocks were painful. Would not take again!! M 82 3 days
1/13/2018
 1  high cholesterol Depression, panic attacks, anxiety, paranoia, hostility, personality change,EXTREME FATIGUE AND WEAKNESS, chest pain, COMPLETE LOSS OF APPETITE, Couldn't take statins due to arm and leg pain. Lipitor caused zombie-like state. Zetia even worse. Two trips to ER for chest pain -thought I was going to die. All tests including stress test negative. Then came psychological disaster-I wished I was dead. Felt so awful, but couldn't really describe what was wrong in my mind, and had no appetite and felt like food wouldn't go down. Stopped Zetia and after first missed dose, my mind felt normal although I still had short periods of depression and paranoia for several days. Off it for 11 days now, and no longer have psychological problems. Although appetite is better, still can't eat much. I am still very fatigued, but I am getting out of bed more. It is very discouraging because I want to do so much, but when the weakness and fatigue hit me, I just have to go back to bed again and rest. Hope to have more energy with each passing day off this HORRIBLE DRUG. I will never take these drugs again! F 82 4 months
9/11/2008
 1  To lower my triglycerides Developed initially a cough followed at 30 days into therapy a tightness of my chest and wheezing, which led to sleeplessness. Stopping Rx now,I am curious how long it will take for symptoms to improve Zetia was effective in lowering my cholesterol M 80 60 days
1X day
9/4/2017
Email
 3  Hi cholesterol, one blockage plus I'm having severe sciatica pain, plus knees/legs. Cannot walk steps w^out cane, but I have arthritis in legs/knees.i cannot take Crestor. Severe pain in legs after one day. I never thought this could be zetia, but probably is, based on comments above. I can barely walk now.Basketball knee problems when in college. I can't really "rate" the zetia. My CPK (MUSCLE damage) bloodwork is always normal. Can't say my problems are zetia related or not. My HDL is185 while taking zetia. Who knows!My heart dr takes Crestor, he says, to keep fr having a heart attack. He never had hi cholesterol! Maybe I need to see another heart dr. F 79 4 years
10mg
7/14/2016
 1  could,nt take statins Read ratings and can say DITTO to most every one . Was on Zetia for four years, and finally said NO to Doctor. I,m better but wonder how long muscle spasms will continue. Have heard of someone off three years and they continue. I,ve been off four months. Now having trouble finding blood pressure meds. which don't effect muscles. Doctors have NO idea of the dire sideeffects of drugs such as Zetia. They should all be required to read reports on this web site. Just remember we have the right to stop any drug we feel has such bad effects on us.Of course , check the web to see how to get off. Some drugs have to be quit gradually. But not Zetia !! F 79 4 years
4/11/2008
 1  cholesterol Just took it three days and am experiencing severe pain behind my right knee, numbness in right foot and some numbness in left fingers. Also twitching in right eye. I am grateful that I immediately decided to check this out before I took it again tonight. Three times and no more. Thank God for all of those who wrote their comments Saved me from misery I do not need. I had enough misery with Toprol XL. I will keep eating oatmeal as it was working and did bring my numbers down to 235 from 270. Don't know why the doctor did not just say ' keep eating oatmeal'. No side effects with oatmeal! Do they get kickbacks from pxs. 79
2/12/2009
 1  control cholesterol Took it in AM with other HBP meds so I didn't know which one of meds was making me feel so bad all those yrs. Asked cardiologist if there any meds that could be changed and said no. Said this is as good as it's going to get. I finally figured it out myself. Noticed about 45 minutes after taking meds how bad I felt, very toxic and debilitating until about 4 or 5 in evenings and I observed I did not have the affect after I took my night med which did not include Zetia. I stopped taking it with AM meds 6 month ago and immediately noticed an improvement and whole new world opened up to me. Haven't felt this good in years. I am very angry with the cardiologist for the years of suffering. It's too bad I didn't figure it out sooner. M 79 5 years
10 1X day
1/21/2018
 1  Tlower cholesterol and triglyceride Excruciating foot, ankle, calf, thigh cramps when lying down, depriving me of sleep. Had been on Lipitor and Zocor previously, but lost my memory on those drugs. Taken off statins, put on Zetia. I've had high cholesterol all my life. I am 78, otherwise healthy, but when those cramps "grabbed" me, I wanted to shoot myself. Took myself off Zetia two weeks ago. I have an occasional leg or thigh cramp, but NOTHING like hwen on Zetia. Am hoping the cramps will disappear the longer I'm off that drug. I plan to live with my high cholesterol and triglycerides... no more drugs.. F 78 4 months
10 1X day
4/9/2013
Email
 1  high cholesterol Unusual headaches plus G.I. tract in an uproar w. 6+ bowel movements per day. Cold sweats waked me at night. Body aching all over (maybe residual from high dosage Zocor taken up to 2 weeks previously.) I quit Zetia after 2 weeks, and the headaches and bowel disturbances immediately disappeared. Am now taking Coenzyme Q10/vitamin E and Omega 3 capsules for recovery while investigating alternatives to these dangerous pharmaceuticals. F 78
7/29/2006
 1  To lower my LDL . Extreme fatigue, Upper respiratory infection and depression with overwhelming feeling of pending doom. Cognitive dysfunction. Once stopped symptoms improved or ceased. Unable to take statins after trying several. F 78 0 months
10mg daily
5/12/2017
 1  Cholesterol Neck pain, slept day and night, lose of taste and after being off of zetia 2 months still cannot taste food, loss of weight Do not take this, pharmaceutical company should be sued, it has caused terrible health reversal M 78 2 weeks
40
6/20/2016
Email
 1  High cholesterol Bloating diarrhea has constipation fatigue I'm so grateful for this site. My doctor said it wasn't the medication but I knew it was. I felt like I was losing my mind when he said it wasn't the medication thinking I might have cancer or some thing. After reading these comments I will be going off the drug and never taking it again F 78 20 days
10 1X day
3/13/2022
Email
 3  Lower CHLOSTEROL WITH lipitor 40 mg Joint pain in legs Both statins WERE generic F 77 2 weeks
10mg
11/4/2017
Email
 3  Cholesterol/can not take statins Somewhat upset stomach. I feel as though I need to eat something to settle my stomach. Have dropped to taking 20 mg three times a week and 200 mg of Q-10. I tolerate that level well. A hint for all who have joint/muscle pain with Zetia or any of the statin drugs: 200-300 mg of co enzyme Q-10 a day helps considerably. It takes 2-3 weeks of Q-10 before most people begin to feel some relief. M 77 6 months
1/11/2008
 1  high cholesterol stuffed nose, pain in hands, i am discontinuing this drug. M 77 4 weeks
2/13/2007
  

ZETIA  (EZETIMIBE):  Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. Ezetimibe may be used alone or with other drugs (such as "statins" or fibrates). Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet. Reducing cholesterol may help prevent strokes and heart attacks.   FDA Approval Date: 2002-10-25 (Sources: U.S. Centers for Medicare Services, FDA)

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