CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender males first.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  anxiety, mild depression I did experience some night sweats while on the medication. I did not experience a loss of sexual drive and did not lose/gain weight. Took 20 mg a day. Cymbalta completely changed my life. I am 25 years old and have suffered from anxiety and depressive episodes since 16. After much consultation with my doctor, we decided that cymbalta would be the best choice. I still get mildly sad sometimes or nervous but only for short periods and I am usually able to just stop thinking negative (which I could never do before). I have been happier in the past 2 years than I can ever remember. I even stopped taking it for 4 months and was not a terrible experience. I did not quit instantaneously and went for about 2 months taking less and less each week. I don't think the medicine numbs your feelings and taking a relatively small dose may really help someone experiencing multiple side effects. I have taken 20 mg. a day the entire time. M 25 2 years
10/7/2009
 5  depresion None so far, and I have been taking the same dose for almot 2 years. M 46 2 years
10/15/2009
 5  major depression extreme ongoing and continual nausea, delayed orgasm, numb hands & feet been on 120mg for 12 months, from being suicidal am now back at work full time, feeling normal again other than the side effects. M 38 12 months
10/27/2009
 5  anxiety I am always tired! other then that, no side effects since the first couple of weeks when i began the medication back in december of '07 I think i've always been somewhat tired so i cant blame it all on cymbalta. however the medication has helped me so much with my anxiety. my sex drive has decreased but my orgasim has gotten more intense, especially after going from 30 to 60mg. I hate beng tired all the time, but i am more calm and i hardly get worked up. i can cry and have regular emotions though. sometimes i feel weird and i cant explain the feeling, but i think its normal. M 26 2 years
11/21/2009
 5  Depression & Anxiety The only side effects I have are a little increased sweating and loss of libido. Cymbalta, which is an SNRI, seems to help me better than the SSRI's like Prozac, Zoloft, and Paxil. Cymbalta knocks my anxiety right out and just relaxes me. It's a very well-tolerated drug for me with very mild side-effects. It also seems to give me energy as it keeps my seasonal depression at bay. I love Cymbalta! oh yeah, it is also cheap without insurance, about $120 a month for 30 days of 60 mgs. M 27 2 months
11/29/2009
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 5  Severe Depression, Social Phobia Possibly tiredness/sleepiness (though I've felt that way long before starting Cymbalta). By far the best antidepressant/antianxiety medication I've tried. Both my depression and anxiety have abated significantly, though there is some of both left (plus the tiredness, which I suspect could be depression-related). I'm already at 120mg and would like to go even higher. My sexual performance has improved greatly, as has my concentration and even driving skills! It's really interesting how the same compound affects different people in so many different ways. I definitely recommend at least trying Cymbalta. M 41 1 years
12/15/2009
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 5  Depression and Pain from Fibromyalg Cymbalta has had No Side effects that I know of for Fibromyalgia. - Lyrica is different, but is also FDA approved for Fibro and I had to lower my dose to alleviate the side effects of sweating at weird times profusely. - Savella is the 3rd drug approved for Fibromyalgia & this drug I could not tolerate as I sweat constantly with this medication & woke up to a soaking wet bed every morning. I did try this earlier in my life when needing a Depression drug to combat the Constant Pain from Lumbar Stenosis in my lower back, that caused pain down the sides of both legs. However, I only gave this med 2 weeks to work & I did not notice improvement and stopped taking it. I was not having Fibromyalgia symptoms at the time. - Now that I have been diagnosed with Fibromyalgia for the past 4 + years, my beloved Pain & Physiatrist Dr. Cathy Gao, recommended that I see a Psychologist to see what was causing my Depression & if he thought that my problem was in fact related to the Fibro & he ultimately prescribed the Cymbalta again, but had me stay on it for 4 weeks this time. He filled me in about Cymbalta & how it is designed to work for Depression and as a Pain Blocker & that it is only 1 of 3 drugs approved for Fibromyalgia. - After 4 weeks, I had fantastic results to complement the Lyrica that I had already been taking. I am happy to say that I have been able to continue working since that time. With this being said and my having 3 Surgeries to alleviate Lumbar Stenosis from L3~S-1, my Surgeon told me that I am the only Patient he has that still has a Job. Dr. Paul McAfee is one of the Best in the Business of Orthopedic Surgeons & he did a Fantastic job of inserting 2 Prosthetic Disks, 3 rods & 6 screws over the 3 Surgeries, with my last being about 1.1/2 years ago, and he had a new way of entering that was far less invasive, called an X M 46 2 years
60 1X day
3/24/2013
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 5  Depression/ Anxiety The worst I got was Cotton mouth M 26 3 years
60
2/15/2014
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 5  nueropathy none Works very well off label for nueropathy! M 61 3 years
60mg 1X day
11/12/2014
 5  Depression & Anxiety Only initial side effects: Insomnia Really great medication for depression and anxiety. Stick with the drug and ride out the initial insomnia. It will pass. Don't let your MD talk you into Trazodone for sleep. You won't need it. After 2 weeks you will be sleeping just fine. M 45 6 weeks
60mg 1X day
11/14/2014
 5  Osteoarthritis Dry mouth 24/7 pain is gone M 64 13 days
60 MG 1X day
4/16/2015
 5  depression/anxiety, pain ...no side effects. ...easily tolerated. Works as described. I don't know about those other posts with all those freaky side effects and/or withdrawls? I think its mostly their imaginations? M 63 2 years
120mg
5/13/2015
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 5  Major depression Dry mouth, constipation, Weight gain It's the WEIGHT issue that is most disconcerting about this drug, the longer you take it, the bigger problem you have... Mostly in keeping it down. Even good diet and modest food intake doesn't help much. You might have to excersise every day hard to keep yourself at a constant weight. Other than that, it's a good drug M 61 1 years
60
6/11/2015
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 5  Fibromyalgia None known. Tried to see if I could get off of drug, but found that my foot pain was so bad that I could barely function. This is one of the several drugs I take to lead a semi productive life and still able to work full time. Quality of life is still somewhat impaired, but I must keep working for at least 10 more years & realize work gives me purpose to get out of bed at this time of my life. M 49 10 years
90 1X day
1/15/2016
 5  Pain,anxiety I feel calm ,energy M 46 1 days
20
2/4/2017
 5  Depression None Saved my life. I am very grateful for this drug, nothing else worked M 61 10 years
50 mg 1X day
5/30/2018
 5  Major depression, anxiety Sweating, some low libido Great for energy and motivation. Gets me out of bed doing what I need to do. Works very well along with my Wellbutrin. M 37 6 months
120 mg
3/5/2020
 5  Panic attacks from Stress No side effects observed. See my review below I want to provide my review. I want first of all to inform all people that because a particular pill worked on somebody, it doesn't mean that it will work on all. I have many years panic attacks from Stress, while past year I had also negative thoughts. I started in June 2019 to take cymbalta 30 mg with the goal of going up to 60 in the next month. I didn't have any results yet so in the beginning of July I went up to 60 mg (of course as per my doctor's advice) After almost a month I started feeling a lot better. It really helped me a great deal and I would like to add the following : People on internet write their opinions scaring others. I have seen countless post about weight gain... For me it gave me the mood to do more exercise and from 85 kg I went to 75 kg and started being fit. Don't listen to every kind of bad review out there. It may have been bad for someone, but for others it can prove to be a good thing. I started trying to expose myself more to situations where I had panic attacks. My negative thoughts are almost gone. Give it a try (after first consulting your doctor of course) I wish you the best of luck. I know how bad it is to experience psychological problems.. I know how devastating it is for people. Don't ever think that because you are taking pills you are weak. And don't ever think that you get crazy. It's the fact that you realize your problem that makes you not crazy! I pray for all of you. Smile and try not to overstress yourselv M 31 11 months
60 mg
6/3/2020
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 5  Depression Sexual disfunction Withdrawal symptoms I experienced were: brain zap, brain fog, anxiety, vivid nightmares. M 29 10 months
30
7/4/2021
 5  Depression/anxiety Nausea and insomnia for a few days Works extremely well with aripiprazole 5mg. The constant negative and worried thinking has gone. I feel peaceful and even joyful M 43 3 weeks
60 1X day
10/21/2021
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