Drug Ratings for CYMBALTA

Average Rating: 2.8 (2279 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)   

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    Charts & graphs: Reviews Summary for CYMBALTA  | Top 10 Adverse Effects (reported to FDA)

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
sort down sort up F  M  
 4  Depression If I miss a dose I get dizzy. Sexual Side effect. Difficulty getting / keeping an erection. Dificlty obtaining orgasm. Worst symtom is hot flashes and night sweats. Has helped me better than Wellbutrin, Paxil, or Lexapro. Sexual Side effects are tolerable but the hot flashes and night sweats are REALLY annoying! But I tolerate because it helps the most with depression. M 40 1.5 years
8/16/2006

 4  Nerve pain in Back (Trigger Point) Loss of sex drive was the most pronounced side effect. Tired in the first 2 weeks, insomnia and dizzyness. Otherwise felt great. Have gone on/off the drug 3 times and not experienced significant problems. Very positive impact on pain - I have had chronic back pain for over 10years, this is the only thing that has worked. Positive change in overall attitude and stress. Only downside is the sex drive. M 33 3 weeks
11/7/2006

 4  Depression Worked pretty good. Made me rather irritable but when i combined it with tryptophan, my irritability went away. Only SSRI that didn't give me sexual side effects. (20-30 mg)After about 2 months on it though, i started developing this weird feeling in my head. Like a pressurized feeling. Anybody else have this side effect? I was pretty satisfied with its effectiveness and side effect profile. It also seems to work excellenty when combined with Tryptophan. M 21 3 months
9/12/2005

 4  depression headaches and nausea almost gone now This is my second entry. I am coming off of effexor and and now down to 150 mg effexor and 40 mg of cymbalta. I notice my mood is ok, my thoughts are clear and most of all I am not as tired which is the main reason I wanted to get off effexor. M 35 17 days
6/9/2006

 4  Concentration, slight depression Hypomania. Slight bladder pain when running. Higher heart rate when running. Exstreme loss of apetite (probably due to hypomania). Good for me, because I have Zyprexa and I gained 20kg) It is great, but I am slightly hypomanic, so that maybe doesnt count. It is a strong drug for major depresive disorder I am probably going to take just 15mg (split the capsule and fill another one). I can finally feel like a normal human being not thinking I am very bad and have no qualities whatsoever. I stabilise with Omega 3 in the evening to fall a sleep and of course Zyprexa. Allmost no side effects whatsoever. I am actually bipolar with psychosis and I dont want to take moodstabilasers, because I cant read when taking them. Good luck to all. M 24 6 days
9/18/2007
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 4  fibromyalgia & mild depression first week. On first day, burning down legs and feet so hot on bottom felt like fire. Nervous feeling in heart/chest area or upper stomach like getting ready for a navy jet launch. mood elevated. energy elevated. pain in gut on taking for an hour. i hope that pain is less, it seems so. M 60 7 days
8/2/2006

 4   Suffering major depression and severe insomnia. Within a week I was sleeping well again as it reduced my anxiety and panic attacks and took the edge off the depression.Side effects were low libido and uncontrollable body twitches at night and when resting. The Cymbalta really helped.It took me from wanting to die, or thinking that I would cut my legs off if it would ease my depression. I have now gone pretty much cold turkey after 5 years on it because I am not sure if I am still in a depressive frame of mind.Unfortunately issues causing the depression are still there.Withdrawal symptoms are headaches, dizziness, and crying at the drop of a hat. M 50 5 years
60 1X D
1/13/2013
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 4  anxiety, pain, depression Heavy GI illness for 2 weeks, helps with anxiety and depression. Still dealing with chronic pain. Find that it takes 2-3 days to recover after a workout. I taker 30mg in am then 60mg @ night. Tried 60mg in morning and couldn't keep my eyes open. M 39 2 years
90mg
12/4/2012

 4  Depression and Anxiety I had insomnia problems before Cymbalta, the insomnia is maybe a bit worse now but I seem to have more energy during the day. I've tried a lot of different anti-depressants over the past 15 years (Prozac, Effexor, etc, etc) and for me Cymbalta has been the best one. After 2 years at 60mg my depression has just started getting a bit worse again so I'm thinking of aasking the Doc to increase my dosage to 90mg per day M 52 2 years
60mg 1X D
1/1/2013

 4  LBP (Lower Back Pain) Dry Mouth, Night Sweats Been taking Cymbalta for 2 weeks, started @30mg 1st week then @60 now. Back pain went from 6-8 level to 1-3 level. Very happy about that, am able to function in all areas. Concerned about the long time effects concerning sexual reactions. I already take 3 blood pressure pills (for 11 yrs) to keep my #'s low. prior to Cymbalta M 43 2 weeks
60mg 1X D
3/22/2012
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 4  chronic lowback pain I started on 30mg 1x per day and felt very tired at first. After I got used to it I went to 60mg.Had some sexual side effects at first but they subsided. After 2 lower back surgeries for herniated discs I was in constant pain. Cymbalta helps take the edge off and reduces any nerve pain.Also makes me less afraid to go out and live my life and to stop focusing on my back so much. M 41 3 months
60mg 1X D
5/3/2012
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 4  Low back pain and depression I have not had any side effects and hope I won't. So far it has lessen my low back pain and made me more connected with life. Started 30 mg for 15 days before going to 60mg and it has worked fine. M 30 3 weeks
30mg/60mg
1/30/2012
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 4  depression anxiety PTSD OCD none but nausea very good med but very very expensive M 45 2 months
60 1X D
12/15/2011

 4  Depression muscle and joint pain I have no horrible side effects from this med. My apologies to anyone who might be offended by the following. I obtain an erection and orgasm much more slowly than before. My muscle and joint pain is almost totally gone. What depression I had has reduced alot. Situational anxiety has decreased substantially. M 51 1 months
30mg 1X D
11/17/2011

 4  stomach pain and anixiety Coming off drug I have blood shot eyes now. Dizzy. I gained 20 lbs in one year. I workout every day and I WAS in good shape. I was hungry all the time and I drank too much When I was on it I did feel more confident. I would not have decided to quit taking it if it wasn't for the weight gain. I don't think he causes weight gain but it does make you want to eat more often. I ate at 10pm every night, an extra meal. I felt like it didn't matter, so what, who cares. I was a little foggy and I did not like that either. M 47 15 months
20 1X D
7/20/2011
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 4  Treatment resistant depression A little dry mouth, headache but nothing that lasted more than 3 months. This med has worked great for me. I occasionally still have a bad day or two but that's normal for everyone. Recently, it started pooping out (depression/anxiety has come back) and I'm bummed. I also take 150 mg Lamictal to augment. Dr. has added Lexapro and will post on that after a month or so. I M 37 3 years
60 1X D
3/24/2011
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 4  Depression/Anxiety Almost impossible to reach orgasm. Felt castrated by this medication. Uplifted mood, more positive attitude were the key benefits for me. Cymbalta is the only antidepressant medication that ever helped me. The first three days of taking it were like hell, so much so that I nearly quit the medication from the very beginning. My pupils were dilated and I felt nauseous. A coworker asked if I was ok and said that I looked like I was about to puke. My doctor told me that it could take 4-6 weeks before I noticed any benefits and to give it a chance so I did. Pushed on through the first few rough days and after the first week I felt ok. It was right after the 3rd week of being on the medication that I definitely noticed a positive benefit. I found myself just being in a more positive mood all the time, which was a great improvement because just weeks before I was always in a more negative/down mood. The only side effect that I noticed was a big one - I almost couldn't have an orgasm and this caused relationship problems for my girlfriend and I. When I finally did reach orgasm (and it took alot of work) it would be a very little one. Also, the semen that came out was a very small amount and seemed almost a different color and consistency than normal. I pratically felt castrated while taking the Cymbalta. After a year of the positive benefits and uplifted mood I decided to ween off of it and have not felt the need to go back on it since. I would recommend talking to the doctor about gradually lowering the dose over a period of a couple of months. The withdrawal from quitting this medication can be absolute hell if M 34 1 years
60 1X D
4/17/2011

 4  Post Lyme Fibromyalgia Side effects: dry eyes, sight digestive changes - constipation and occasional flights of nauseated feeling. Initially weird dreams. Lately have had increasing bouts of itching skin and tiny pimple-like eruptions feeling like insect bits at groin and underarms. My Fibro had nearly incapacitated me and this med works wonders to keep me functional and able to manage my pain at tolerable levels. I have learned NOT to miss a dose when traveling of for other reasons as this causes a revisit of pain increase. If lack of meds is coupled with other fibro-triggers such as stress or lack of sleep, I have a full fibro flare-up. So for me, this drug has been wonderful, but concerns of liver damage keep me getting regular liver studies M 58 2 years
20mg 1X D
3/6/2011
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 4  Depression and anxiety Hot flush on whole body. Unable to sleep. Dry mouth. Shaky legs, feels like weak. Cymbalta makes me feel good. I never tried other AD. The worst is the hot flush I get when I took it before I sleep. After a few hours, I will be awoke by the hot flush in my body. I don't sweat. Just inside my body. My doc ask me to change it to morning and everything is fine now. I realize if I had hot flush, I just need to sweat it out by doing some excerise. M 30 1 months
30 MG 1X D
3/13/2011

 4  anxiety/ depression Diarrhea at first, for the first few days, serious mood change when stoping usage. Otherwise the drug works like a charm, especialy for anxiety. Found it almost impossible to have depression thoughs. No weight gain, no brain fog- quite the opposite, no memory changes, no sexual side effects- actually the sex drive is quite up, doin it more than once daily on average. But stopping it was very hard, as the mood swings, and depression thoughts crept in without notice, had to go back on it. M 33 5 months
60 mg 1X D
5/11/2011

 4  bipollar poor sex drive, weight gain, crazy dreams and odd sleeping patterns I started on 30mg 2 weeks and than moved up 2 60mg after i had a bad time with a broken back for 2 years pryor in that 2 years i cut my self 2 shreds to help ease my back pain. Sounds dumb but was effective now 4 months on i feel fine with cymbalta. my partner has stood by me the whole but hates the lack of labeito maintaining erections and the waking up every few hours i seem 2 do now. recomend it for bipolar. M 27 4 months
60 1X D
5/10/2011

 4  GAD, OCD. insomnia (treated with low dose Risperdal), costipation, mild drowsiness, delayed eiaculation. cymbalta day by day let me know what is really GAD. a destroying disorder that does not allow u to life free. i take it in combination with Risperdal, as said, and Bupropion 100 mg daily. M 24 1 months
60 mg 1X D
10/20/2010

 4  Depression Fibromyalgia at start dry mouth& metallic taste; started clinching jaws which causes headache, tooth and gum pain & neck pain. The dry mouth is very insignificant compared to depression. For those people who do not understand why anyone would take these drugs with all the side effects YOU HAVE NEVER SUFFERED REAL DEPRESSION. It is necessary to find one with fewest side effects and everyone is different. What can you live with?? I am assuming the Cymbalta is the cause of the clinching. I had the same thing with Lexapro along with some other things. M 68 2 months
1X D
8/15/2010

 4  anxiety dry mouth, sleepiness started to not work as well after 4 years M 52 4 years
90 1X D
8/18/2010

 4  Bipolar Depression Jaw clenching, I was hospitalized at Four Winds for three weeks for depression. They put me on cymbalta. It has definitely helped tremendously with depression. I am grateful for this medication. M 20 3 months
60 mg 1X D
8/1/2010
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 4  Moderate Depression, Severe Anxiety Night sweats, constipation, taking longer to climax during sexual intercourse I am glad that I started Cymbalta before I came to this site. I have only been on Cymbalta for 10 days but I am already starting to feel so much better...I've gone years and years being depressed, sometimes severe sometimes moderately. The disheartening thing is that the people who are most likely to post on sites like this are the few that have had bad side effects. However, remember that everyone is different and out of ALL those taking this medication only 20-30% end up with severe side effects if any at all. Every person physiologically is different and processes meds such as Cymbalta differently. There is a balance...there are many who are taking this medication and have not had any side effects at all and even the ones that have, it has been worth the side effects. I am hoping that my experience with this med continues and that it gets more effective as time goes on. M 32 10 days
60 1X D
7/18/2010

 4  Depression (Dysthymia) , Anxiety Decrease in libido (not totally gone), ejaculation takes longer, morning nausea/loss of appetite, constipation, more frequent urination, excessive yawning (first two weeks), penile discharge (first week), jittery/high energy (first week), weight loss. -I also take 200 MG of Provigil twice a day for Narcolepsy. -For the first two weeks I took clonazepam for the anxiety until the Cymbalta kicked in. - So far it has worked great for me and the side effects have not become severe enough to cause an issue. I was somewhat hyper/ talkative the first week (a major shift from being extremely quiet, removed, and antisocial), but that was mostly with family members. If I eat much of anything in the morning while I still have the mild nausea I will get diarrhea, otherwise I have had some mild constipation but that usually only makes me take a little longer in the bathroom so I moved some books in there for reading (reading has always been difficult because of the lack of interest, and excessive daytime sleepiness that would cause me to fall asleep repeatedly and become disoriented). My general level of anxiety has dropped quite a bit. I still recognize some of the thoughts and feelings I had before, but they no longer keep me from being able to do things as simple as taking a walk and it is much easier to communicate. My motivation level has increased a large amount and allowed me to actually have interest in creating art (an interesting/nice feeling for someone who has gone to a Fine Arts college for the last 3 years) and in life in general. I have gained a good amount of energy throughout the day and am actually sleeping better (which is still "fragmented sleep"). - I'm going to keep watching things. M 21 1 months
60 MG 1X D
6/10/2010
Email
 4  depression, anxiety constipation, light headedness, some tingling, lightheadedness, spacyness. slight loss of libido and takes longer to ejaculate. stomach pains initially, but went away after a few days. This is my second try taking Cymbalta. I tried it 2-3 months ago and my doctor took me off due to the inability to ejaculate. However, after trying two other medications, Cymbalta had the only side effec that I could see myself coping and dealing with--so i went back on it. During this second go-around, I only take the medication at night (versus the last time i was taking it in the morning). I find this works so much better. I can ejaculate at night, but not in the morning. Maybe the drug has worn off a bit at night, not sure why. Also, the second time around, the side effects seem to be less severe than before, especially the brain zaps, this time don't notice it as much. M 41 1 weeks
30 MG 1X D
5/4/2010

 4  Social anxiety, small depression Fatigue (sleepy in the afternoon), decrease in appetite, delayed ejaculation Helps with social anxiety, doesn't really help depression. M 18 2 weeks
60 mg 1X D
4/13/2010

 4  depression anxiety side effects were a little tough at first but i was told you have to stick through it to see if it works. it takes weeks to get full benefits . i am now able to function day to day. still dont feel good all the time but it put a big dent in my problems IF YOU RATE THIS DRUG WITHOUT GIVING IT THE PROPER TIME TO WORK THEN YOU DID LISTEN TO YOUR DOCTER IF YOUR NOT WILLING TO COMMIT TO THE WEEKS IT TAKES DONT WASTE YOUR TIME AND DONT POST HERE THAT YOU TRIED IT FOR 3 DAYS AND IT DIDNT WORK!!!! i do understand that these drugs do effect people differently and have considered this before my statement here. thanks...paul M 46 6 months
60mg 1X D
5/12/2010
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 4  Severe Anxiety Orgasm problems, Decreased sensations during intercourse and loss of erection. Procrastination. No anxiety at all, did not care or worry about anything. First it took me extra time to Orgasm. My wife would have two Orgasms and then it would take me 20-30 minutes. I could not feel anything during intercourse we would have to try manual or oral methods then the orgasm was not very strong. If I masturbated sometimes I would ejaculate but feel nothing. The other problem was I seemed to be so "Happy" that I procrastinated small projects and paper work. In the past "Mild" anxiety made me successful. No anxiety really slowed me down. I have been coming off the drug but I am getting a little panicky at times and don’t want to take Clonopine either because it makes me very tired. This drug would be ideal if it was not for the Sexual issues. I felt great and could teach myself not to procrastinate. The sexual problems where terrible. M 47 4 months
1/27/2010
Email
 4  Depression, Anxiety Nausea, loss of libido, unable to orgasm, brain zaps, dizziness, concentration issues, yawning, tiredness, jaw clenching, slight insomnia First, the good. The little things that would make me depressed or sad before doesn't phase me as much. I've noticed that I recognize the situation, but the drug takes the edge off. I fall asleep easier than before. Generally, I feel more content with people and situations. I don't have thoughts of death or dying like before. Now, the bad: I got a bad stomach ache the first day but it didn't happen after the second day. The same goes for the nausea, it seems to be happening less and less the longer I am on Cymbalta. I get occasional brain zaps, but it isn't too bad to where I would stop taking it. I am able to have an erection with no problems, but not able to orgasm. I am not sure if it is the drug that makes me not too concerned with this sexual side effect as I would consider myself a very sexual person. I am hoping that in time I will be able to orgasm like before, but I don't know how long that will take. If anyone has had success or advice on this side effect please email me. I don't want this to be a permanent situation or get worse. M 41 2 weeks
30MG 1X D
2/5/2010
Email
 4  Fibromyalgia Pain Sexual Side Effects such as inability to orgasm or have sex for prolonged periods of time. Weight gain at first which subsided over time. Pronounced hair loss. I was virile until I started Cymbalta. Erections were rock hard and hair was thinning, but was not bad. Two year later, It's hard to achieve an orgasm or even become erect at times. It's hard to ween off Cymbalta, as well. I take this with Lyrica to help with nerve damage. Both work well when combined for the pain. Sex drive is still there, but I need to take Cialis or Viagra to be a rock star in the bedroom again. M 43 2 years
30 MG 1X D
2/6/2010
Email
 4  anxiety and depression Like most drugs of this type, there are side effects when first starting such as insomnia, tired feeling, sweating, and these can be bothersome. Believe me they do go away after a week and it is definatly worth hanging in there. I was on this med for 2 years and foolishly decided to stop. Without noticing, I fell back into a major depression. See additional comments. I just restarted Cymbalta after being off of it for 6 months. I started using 60mg per day almost 2 years ago for anxiety and slight depression. Wow I had no idea how well it was helping me until I stopped taking it. Within a month, I went into a severe depression. I tried starting Cymbalta again, but developed annoying side effects. I tried 6 other SSRIs and had the same trouble. I thought I was going crazy. My Dr could not figure it out. He knows me and was shocked that I had become so severly depressed and intolorant to everything. I had always taken Xanax as needed for Panic, and even Xanax stopped working. Anyway, Dr prescribed Lyrica which is rather new for depression, and although it slowly helped, I developed a rash from it even at a low dose. He next tried Lamictal, and after tapering up for over a month, at 150mg per day I was feeling slightly motivated to leave the house, but the med made me short tempered, nasty, did not help anxiety and the crazy side effects like acne, weight gain, mouth sores etc. were not worth the benefit. The worst part of Lamictal was how manic it made me. I think Lamictal is probably great for Bi-Polar disorder, but I am not bi-polar. Anyway, Out of desperation, I decided to force myself to deal with the side effects of starting the Cymbalta again. The first night was hell not sleeping, stomach ache, dizzyness blah blah. I am so happy to report that after a couple of days telling myself, Just deal with it, I am starting to feel great again M 41 5 days
30 mg 1X D
2/28/2010

 3  Neuropathy Side effects included dry mouth, weird dreams, total personality change from grouch to happy all the time. Until recently did not realize that my sex drive increased almost to an addiction. For the neuropathy I had to change to the 60mg per day because the insurance woul not pay for 2 30 mg. The 2 30mg were working pretty good but the 1 60mg was not working as well. Doctor changed me to 2 60mg a day and that put me over the edge. My sex drive was making me become a nymph and I ended up having sex in my office. Got caught and fired. Be cautious if you are starting this pill about the hidden side effect of thinking you can do anything. The happy feeling all the time was great but now after all these years of working to loose a job and damage you mariage is not worth it. It did help the pain in my feet. Currently being weened off of it. M 64 370 days
30 2X D
2/17/2010
Email
 3  Anxiety nausea, slight headache and sweating. I understand this is just the first day. I wasn't sure I could deal with the nausea but it seems to be getting better as the day goes by. I have noticed a great deal of alertness with me throughout the day and full of energy hopefully this will continue. I will respond back after a few more days. VERY worried about Weight Gain! M 39 1 days
30 1X D
3/5/2010

 3  FM/CFD/fibromyositis/dystonia hallucinations, loss of appetite, night sweats, night terrors, horrible after taste, etc... Eventually subsided. (Thank God!) Doctors haven't really figured out what type of pain disorder I have. However, Cymbalta has been helpful. At first, it was a NIGHTMARE! Getting used to it was difficult. I stopped taking this medicine 4 times, when my doctor told me I had to take for at least three months in order to effectively rule it out as ineffective. Took it for a while, and it proved to be helpful. Last time I visited Johns Hopkins, the dr. decided to increase from 60 mg to 120. Now that I'm used it, the side effects have subsided. M 30 1.5 years
60 mg 2X D
5/19/2010
Email
 3  anxiety/depression anxiety, drowsiness, insomnia, chills, loss of appetite, sweating, cloudiness, memory loss Over the last 6 months I've experienced the separation of my parents after 38 years, life-threatening surgery for my mother, first death of a family member and extreme job dissatisfaction. The collection of these events have made me pretty depressed and anxious. My relationship with my fiance has really taken a blow as a result of these occurences. I began seeing a therapist a couple months ago, but I wasn't feeling the effectiveness. I decided to reach out to my physician for information regarding medication treatment. He prescribed Cymbalta, which I've been on for the last 4 days. It's been pretty horrible, thus far. I've been anxious at times, paranoid, very drowsie, sleeping for no more than 3 hours per night, loss of appetite, sweating, very cloudy thinking, forgetfulness. I'm toughing it out for another couple days, in hopes that my symptoms improve. Wish me luck! M 28 4 days
30 MG 1X D
6/11/2010

 3  depression dry mouth,insomnia,anxiety it only somewhat works,i still need to take buspar to help relieve residual anxiety M 38 5 years
120mg 1X D
4/19/2010

 3  Depression and anxiety Decrease in Lidido, Difficulty in ejaculation; Increase in sweatiness I wish they could develop an anti-depressant for men that doesn't strip your libido, or make it difficult to orgasm. That is my BIGGEST complaint with Cymbalta. Despite it being one of the newest on the market, this side effect is something that the makers of Cymbalta can't seem to eliminate from their product. On the positive, Cymbalta has helped me with my anxiety. I no longer get butterflies in my stomach. It has helped my depression about 60%. Would I recommend it to another man? Depends how much they value their sex drive. M 43 1.2 years
60 MG 1X D
5/4/2010
Email
 3  Nerve Pain extreme anger, hate, and rage, nightmares, daily suicidal thoughts i have to take it, i don't have any other choice at the moment, and i'd rather be hateful than live with all the shooting nerve pain through my body. M 31 8 months
60mg 1X D
4/16/2010
Email
 3  depression, GAD, DOC. HUGE costipation, somnolence, loss of libido. it seems to be uneffective to me. I completely had to change med to stay well al least of my real state. i don't recommend it. M 23 1 months
60 mg 2X D
4/21/2010

 3  Neuropathy Acute loss of interest in sex, inability to reach climax - no sensitivity, mild constipation, dry mouth, uncontrollable yawning Seems to help some with neuropathy, although it doesn't completely ease the pain and burning sensation. The first time I tried it, I got very nauseated and stopped taking it, but decided months later to take it with food and didn't have that problem again. Will probably stop taking it and go back to neurontin because of sexual side effects. M 65 3 weeks
30 mg 1X D
6/16/2010

 3  depression at first none felt great after approx i week got this foggy feeling, always tired, have a not care to do any thing attitude this is my second time on this first time quit cold turkey not to may problems other than those silly brain zaps. this will be my second and last time taking after one day i feel 100% better hopefully tommorw will be the same M 43 30 days
30mg 1X D
7/10/2010
Email
 3  Major depression I get brain buzzes, headaches, and cannot sleep. Major Depression has been helped but still have anxiety and panic attacks and days when I feel just simply not motivated. Not sure on this one M 42 6 months
120 1X D
7/13/2010

 3  Depression - extremely suicidal Inabailty to orgasm, insomnia, migraine headaches, jaw clenching, feeling 'wired' and speedy. I found the drug very effective at lifting my mood and removing depression. I also found it made me feel more empathetic and connected to people, something i had not felt for a very long time. I found that once the initial start up dose of 30mg was increased to 60 mg, I suffered from migraines for a period of time. Eventually these went away. Also i found it very difficult to orgasm. This actually became worse the longer I was on the medication, and in some ways the only way to have orgasm was to stop taking the medication for a day, then wait till the next day to have orgasm. I also began to find it really hard to sleep, and also felt too racy and speedy. I have recently stopped taking cymbalta - even though the +ve on mood and disposition were very good, I found not being able to orgasm, sleep etc were making me want to stop taking the drug. Since stopping, I definately am struggling again with mood, and disposition... I may try another type of anti_depressant... I'm not sure yet though. M 35 5 days
60 1X D
8/28/2010
Email
 3  GAO Nausea, dry mouth, loss of appetite Has already started helping with my anxiety. Involved in very stressful situation last night and felt very calm throughout. I weighed myself and have already lost one pound in just 2 days from loss of appetite. It's the weekend though, so I'm concerned about the nausea during work hours. M 39 3 days
30 1X D
8/22/2010
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 3  Fibromyalgia Nausea, yawning, and sweating. The first two side effects went away after 2 weeks. Chronic pain from FM went away within 2 weeks. My doctor tapered me off from 90mg to 0mg within 2 weeks. The first day completely without Cymbalta was the day when hell opened up for me. I am a happy, laid-back and healthy person (besides FM), but I felt as if I was posessed by something evil and insane. It was the worst thing I ever experienced in my life. My doctor said I might get brain zaps, but what I experienced was waayy beyond that. A constant feeling of absolute horror and severe anxiety. Terrifying nightmares. If I would have known that, I would never have started taking Cymbalta. M 40 2 years
60+30mg 2X D
11/9/2010

 3  severe depressive episode ringing in ears, constipation, apathy, reduced libido went cold turkey for a week....was HELL, need to be on it now because am suicidal, if i get through this not looking forward to withdrawal M 37 5 months
60 2X D
9/15/2010

 3  Major depression Loss of interest in sex, severe memory loss, inability to ejaculate, need to urinate frequently and immediately, nervous leg, severe withdrawal when I forget to take a dose on time I'm on a combination of meds - Cymbalta, Abilify, Seroquel, & NAC for depression, Vyvance for ADD, and Metformin, Simvastatin, Fenofibrate, & Diovan for the diabetes from the meds I've taken over the years & the blood pressure is caused by the Cymbalta. I think the meds work okay, but quite frankly, I'm prepared to say that they aren't all that great. Since my suicide attempt in late '09 I've started using MMJ and I go in for regular shock treatments every 8 weeks. Now those two things have been very effective. I've given up alcohol (I never drank that much), and the benzo's the psychiatrists were prescribing, and I don't take/need pain killers anymore I don't live in agony any more and I rarely think of suicide. I've been chronically depressed since I was a teen and it has worsened over time. I told you all of that to tell you this. I'm afraid to stop taking the anti-depressant cocktail I take even though I doubt that it is that effective. Even one day without Cymbalta brings on pretty severe depressive symptoms. Some of that may be because I'm on such a high dose although I've been on as high as 180mg a day for a few years. If I had it to do all over again, when it seemed clear that medications were only marginally effective I would have added MMJ and if it didn't improve, I would have gone to ECT (the PC term for shock treatments) much earlier. If nothing seems to be working for you, consider ECT and MMJ. There is hope. Really. M 53 6 years
120 MG 1X D
2/20/2011
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 3  nueropathy & depression severe bouts of short term memory loss, inability to think of words , near total loss of libido, bouts of sudden onset sweating, frequent urination the "have to go NOW! kind. recent dramatic weight gain, wired lethargy if that makes any sense, developed high blood pressure since starting cymbalta too.... plus more but that's enough, right? Cymbalta works amazingly well for my at times crippling nueropathy. It also helped greatly as I began to suffer from depression which I'm not inclined is Cymbalta induced (why would it work well in treating the same thing it caused?) I am prone to ever increasing instances of an inability to think of a word or name that in the past would have rolled off my tongue with ease (now I'm often resorting to ridiculous sounding multi word phrases in place of the word or name. I'm at this site now looking for something that might replace cymbalta before I morph totally into some pathetically forgetful, sweat drenched, morbidly obease cymbalta victim that even my wife can't love anymore! Oh and for anyone interested I am also on daily pain meds (methadone), also NSAID as needed, Provigil for years because I get so lethargic I tend to do nothing, BP med now, and the wonder cure my doc recently instructed me to try for HORRIBLE cramping (legs and feet mostly) MAGNESIUM and Calcium w/vit D suppliments. This worked immediately for not just myself but also my wife and motherlaw that also suffer from these ...try it if you have the problem! Now I don't dare forget taking it every day! Seems if I do I WILL have a major cramp episode ..did everyone but us know about this? I can't believe such a simple fix has not been common knowlege! I guess there are differnt causes for cramping so it probably does not work for squat for some ...but 3 for 3 sugggests there is a BIG percentage of suffere M 56 3.5 years
60 1X D
11/7/2010
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 3  Depression Oversleep, flat, unemotional feeling. No weight difference. A few nausea spells initially with vomiting. After initial side effects, not much I don't know how to feel about this drug. It is my first anti-depressent. I started taking it for a month and I felt great; but i needed to sleep way too much. I went off it, and felt fine for a while, but then hit a low as I had never had before. I am back on it now, and it seems to be working in a sense. But I don't feel much of anything at all. Cognitively better, sleeping too much can be a problem. Tough to gauge. M 20 4 months
60 1X D
4/5/2011

 3  Muscle pain in my neck. Headache's, dry mouth This drug will cause you to gain weight and keep it. I gained 20 lbs. and sometimes I'll only eat one regular meal a day, two at the most with no snacks. I'm going to wean myself off of this drug because of the cost. ($160 a month) This is a drug that you have to wean off slowly because of the withdraws (ringing in ears, and it makes you feel weird) M 44 5 years
60 1X D
10/22/2011
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 3  depression weight gain , insomnia tired of pills M 43 60 days
30mg 1X D
10/19/2011

 3  Depression Emotionally Numb, Aggression, No Concentration, No Motivation, Excessive Hunger, Weight Gain Starting was tough, 1st 2 weeks were morning doses. Yawning constantly, Moving eyes caused a sensation I can describe only as a brain shock. Yawns were almost climactic, felt like I had run a marathon. The shakes and nightmares were horrible. Night doses helped, except the sexual problems, keeping aroused was almost impossible. 6 Months: Things settled I thought 'I Love Cymbalta',Something finally worked. 12+ Months: Started to notice how I just 'Couldn't be bothered' to do so many things. I was a Gym Junkie, extremely fit and energetic. The desire to eat now rules me, I have gained so much weight and i cant stop. 2 Years: I have changed. Home life fine, wife and I doing great but I am getting horrible mood swings where I just snap, aggression kicks in and I make no sense. I don't hurt anyone other than myself, but I need to smash something and scream. I have no regard for my wife's feelings. This is NOT me, it is scaring me and is getting more frequent. My concentration is getting worse which is making my work suffer (software developer), I am so tried though mostly sleep well, I don't seem to care about anything and thinking things I shouldn't. Cymbalta? I think so, I always felt like I handed over a little bit of control when I started taking it and now I think it is taking more. It gripped me like no other drugs had, and I have been on many. I want off this drug and have made the appointment with my Dr to hopefully get this under way but I am terrified. M 32 2.5 years
60 MG 1X D
10/23/2011
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 3  Anxiety Some sleep disturbance the first week, weight loss I was surprised that there were so few side effects with this medication (I reacted horribly to Effexor). I am not sure I am getting much relief from the anxiety but I am going to keep trying for a few more months. An added benefit has been that it seems to have increased my metabolism. I have lost weight but maintained by normal appetite M 35 3 months
60mg 1X D
1/3/2012
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 3  Clinical Depression - PTSD Nausea, brain-zaps, ED, extreme malaise and apathy, debilitating tiredness, muscle and joint pain, memory and concentration issues... Traded the dreaded Effexor for alleged wonder drug, Cymbalta. Since they of the same ilk, the transfer wasn't too bad. Actually worked okay for the first 9 months (hey, doctors don't have a clue how all these drugs work but they dole them out to millions of us guinea pigs every day) , then everything turned bad: I became so depressed that I wrote my goodbye letters and picked out a spot to park my car where I wouldn't be disturbed once I stuck the hose from the exhaust into the window; I had trouble concentrating on driving and had a rear-end collision; having never been a great sleeper, I began waking up 30-50 times per night so I was constantly exhausted; lost the little that was left of my libido; experienced extreme pain in my muscles and joints... Tried changing the dosage and experienced the worst depression in years... I was looking forward to ending the pain through suicide, I experienced fits of rage at nothing in particular (except my desperation)... it was a full on Dr. Jekyll and Mr. Hyde transformation and very, very scary... I'm now at 120 MG A DAY OF THIS S%*T... THIS STUFF IS EVIL... but so are all the other dozen AD's I've tried over the last 30 years.... is the cure worse than the disease... that is something each of us has to decide for ourselves… M 60 1 years
60MG 2X D
12/12/2011
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 3  Rage/Anger/Inpulse Control Bear in mind that i have been taking Remeron for 11 years, and had to add Cymbalta 2 years ago because I had been experiencing rage/anger (my dr. called it 'impulse control'). It worked for the rage. Get occasional dry mouth, and have had palpitations for over a year. Also began having difficulty sleeping, but I don't know if it's because of the Cymbalta or not. Hmmmm. My memory has gotten really, really bad. Need a change (from Remeron + Cymbalta), or maybe from my other medications (too many to list). M 53 2 years
30/60 1X D
5/28/2012
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 3  Clinical Depression Increased Blood Pressure. Took water pill for years for BP. Due to Cymbalta, I had to take Lisinopril too. 9 months on Cymbalta along with 1 month with Lisinopril meant dizziness and still BP that was too high. When standing up my BP would drop quite a bit which caused dizziness. Cymbalta seemed to work otherwise, but high BP had to go. I quit Lisinopril and am weaning from Cymbalta to Prozac. Never tried Prozac before. M 53 9 months
60 MG
6/16/2012
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 3  back pain WEIGHT GAIN!! sweats I have been taken cymbalta for back pain, 30 mg did nothing for me however the 60 mg helped for about 2 months. I gained about 20 pounds!!! Horrible!! The fat on my stomach sure can not be good for my back!! I wanted off of it. So I decided to stop. BAD IDEA! DO NOT GO COLD TURKEY! I was so sick the 3rd day off of it, felt like I had the flu. I immediately took it again and called my doctor. My doctor brought me down to 30 mg every day for 2 weeks and then every other day. The only side effect now is heart palpitations, which is just annoying. I still sweat like crazy. Hoping that will go away soon and hopefully I can loose this weight I gained! M 53 7 months
60 mg 1X D
7/27/2012

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