CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Depression and Anxiety None I have been taking Cymbalta for a few days now. I am loving it. I have no side effects. I feel alert, focused, and happy. I haven't felt this way in a while. I am very pleased. F 25 1 weeks
4/5/2009
 5  depression and fybromyalgia i was sleepy had alot of stomach problems first week. it caused some insominia, i also felt like i was haviing brain buzz and ringing in my ears. I have hung in there and now the side effect have gone. I am feeling wonderful now. I have not felt like this in years. I am playing with my kids and smiling and laughing everyone can tell. I am cleaning and organizing my house now. I feel like a person. I have to take alot of meds. I have no insurance and my cymbalta is $185.00 a month. I am also on neurotin, tramadol, benazapril for my blood pressure and glyberide for my diabetes. They have not caused any problems yet with the cymbalta. My meds cost about $800.00 all togther. It is hard to buy sometimes. I am a homemaker and i have four little girls. I have been so depressed for the past 2 years and have not been myslef at sll. but now with the cymbalta I have started acting like my old self. i love it. My happy pill. Some of the other meds I take also effects and raises serotonin levels so that may make a difference. But whatever is going on in my brain is wonderful. Everyone who reads this if you have any suggestions on how to get samples or discount on meds please email me at [email protected] Pray for me and everyone in that can not afford there meds. It is a big problem i think in the economy. Lets all remeber to pray for our country and the economy. There is power in numbers and all our prayers can make a difference. F 28 2 weeks
4/6/2009
 5  Depression/anxiety Insomnia, decreased appetite (though that's a good thing in my case; the depression had me overeating). Cymbalta has changed my life. I didn't realize how bad my depression was until looking back on it--I wasn't motivated to do anything, had paranoid delusions, was always achy and unwell, and was just generally unhappy. I started Cymbalta after finally dragging myself to the doctor at my mother's insistence, beginning on 30mg for one week and moving up to 60mg. I noticed a difference within the first week. Now, it's an incredible change; I feel like I'm a *person* again. I have been experiencing insomnia due to it, but with 25mg of Trazodone, that's evened out wonderfully. I'm so happy with this medicine! F 24 4 months
9/15/2008
 5  fibromyalgia/depression First week, a little sleepy, mild and short episodes of dizziness, resolved after a few weeks. Started with the 30mg. dose for 1 week and then progressed to 60 mg. once daily. Had been taking Prozac for about 20 years, but it just seemed to stop working. Became depressed from dealing with daily pain of fibromyalgia and realized I needed help. Doctor suggested I try Cymbalta because it had been used to treat the pain of fibro and has been effective in about 50% of the women who have tried it. I am one of the lucky ones!!! After a week on the meds, my pain is GONE, my energy level is great and my mood has greatly improved. None of the feared sexual side-effects. No problems and very thankful. F 51 30 days
9/22/2008
 5  Painful Sensory Neuropathy During the settling in period I was very sleepy, had nausea, and felt "stoned." But all that went away and now I feel really great. No terrible pain in my fingers and feet and no sexual side effects. I take 120 mg per day. I think that is the highest dose allowed but is common for nerve pain. I think this is a great drug if it fits with your physiology and you can tough it out the first 2 to 3 weeks. F 50 6 months
9/30/2008
 5  fibromyalgia When I first started taking the medication the side effects that bothered me the most was for weeks i had no desire to eat and felt nausea. that went away. immediately , my pain went away due to my medical condition. I have a family of 5! 3 kids including a set of twins! I would not be able to survive without this medication. the other downfall is that it is very difficult to have an orgasm!!! I plan on talking to my dr. about this issue and she said she would be able to put me on something along w/ cymbalta if this did happen. I have yet to do that. I would die without this drug. It has saved me. I wake up every morning and can;t wait to take my happy pain free medication. I can't say enough about this medication. F 35 2 years
2/23/2009
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 5  severe anxiety wicked sick dreams, night sweating, increased sex drive it usually brings out the best side of me EXCEPT when i miss a dose or two, its like a bad hangover times ten... i enter depression and cant get out of bed. F 21 2 years
2/23/2009
 5  clinical depression extreme sweating when am physically exerted,e.g. gardening. Never experienced this type of sweating. whole scalp is sopping and perspiration runs down face. Was on luvox before and never had any problems of this type. Have no appetite yet unable to shed even a few pounds. constipation, lack of energy, wanting to nap all the time. F 64 8 months
2/25/2009
 5  clinical depression insomnia, vivid dreams that continue from night to night as a story, can't lose any weight, no lobido This is the only drug that keeps me depression free even in winter. F 1 years
3/1/2009
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 5  Irritability, anxiety, depression Nausea first couple days and occasionally now. First time I took it side effects were worse. I stopped because of what I read about problems stopping - no problem. I have read so much negative stuff on Cymbalta. I love it. I was on it about 6 months the 1st time but read all kinds of horror stories on the web. I stopped and had NO PROBLEMS stopping but the irritability and anxiety returned. My husband asked if I had stopped so guess it was obvious. I am a better mom, wife, and friend with it. I have 5 kids, full-time job, and full-time college work toward masters. I will take as long as needed and do not fear stopping. F 40 1.5 years
3/16/2009
 5  Depression Night sweats but oddly enough only on my lower body Cymbalta has helped me greatly. I tried 3 other antidepressants which actually made me worse (I had severe social anxiety while on the generic form of Wellbutrin which I never had before) and Cymbalta is the only medication that has worked for me. The night sweats can be severe but since the medication seems to be working it's a small price I am willing to pay. Unlike some of the other medications Cymbalta worked slowly; each day I felt a little bit better. While on the some of the others it almost felt like I was on speed as I was full of energy yet still didn't feel quite right. After a few weeks on them I crashed and was actually more depressed than before I started taking them. I am very thankful for Cymbalta! F 41 5 weeks
3/28/2009
 5  anxiety and depression low blood pressure, nausea, night sweats, vivid dreams. I really love Cymbalta. I have anxiety and depression and have been on and off of Cymbalta. I just feel SO much better on it. As far as the sexual side effects, I have body dysmorphic disorder which is MUCH MUCH worse when i am not on the medication, so sex was not nearly as good as being on it. It does cause some dryness...dry mouth, skin and female dryness, but it is SOOO worth it. I am so much more NORMAL on it....off of it I had really low lows. I think people with problems with anxiety and depression should try different drugs til they find the right fit, but this one is right for me. F 32 2 years
3/19/2009
 5  generalized anxiety initially dry mouth but that subsided after the first week or two of treatment; occasional severe night sweats i didn't know what feeling "normal" was like until i started taking this medication. i began taking 30mg QAM after my PCP put the squash on my request for PRN anxiety meds. she felt as though i needed something more than just a PRN as i have several daily stressors in life that were exacerbating my GAD (major break up, move, hectic work schedule, etc etc). i have suggested it to several of my friends and colleagues who also suffer from anxiety and anxiety-related health issues as it has immensely helped with releaving my daily anxious feelings. i have experienced no weight gain, no lack of sexual desire or no inability to orgasm. i also have not experienced any issues if i do not take the medication at the same time of day. maybe a slight headache but nothing that would need to be treated with an analgesic. i don't know what the withdrawal effects would be like for me but i can't foresee myself wanting to stop taking this med so i suppose i shouldn't WORRY about it! F 28 3 months
3/20/2009
 5  sleep difficulties/fibromyalgia dizziness went away; still have "withdrawal" nausea after naps I take low-dosage, a.m. only, and it regulates my sleep patterns very well. I ACTUALLY REACH DEEP SLEEP, and in less time. I know that because I finally stretch (revitalized muscles) upon wakening, and I remember dreams again F 44 1 years
9/7/2008
 5  Fibromyalgia and depression Dry mouth, reduced sex drive, inability to orgasm, night sweats, weight gain, and hot flashes Cymbalta has eliminated chronic fibromyalgia pain and muscle stiffness. I have been on multiple drugs in the past, but the best before Cymbalta was Trazazone - but it only reduced the pain and stiffness. The pain relief is worth all the side effects. F 63 10 months
8/31/2008
 5  depression/anxiety dry mouth, constipation, weight loss then gained weight back (only 10 lbs), blurrred vision, eratic sleep patterns, sweating at night, vivid dreams, very increased sexual drive- but hard to climax, sometimes very sleepy Other than all the side effects- which I have learned to overlook- I find that they change around-I feel great. I still have some bad days now and then- but I know that they will become less. I don't worry about things like I used to. In fact sometimes I don't give a shit anymore on things that used to drive me crazy with worry. My sex drive increased but the climaxing is so hard if I am able to. I have more energy. I feel much differnet and my advice is to deal with the side effects and see how you feel over all. I wake up a lot at night and have bad sweating...but when I lost my job due to a layoff and did not worry about my future. I knew that this medicine was working. I am much calmer and laugh like I have never before. So give this medicine a shot. It may not be for everyone. Back in the 90's I tried everything and NOTHING worked. So I gave up and dealt with the depresion and anxiety on my own. I was okay unitl my divorce (he was a party dude- not a family man) and then I went d F 40 4 months
8/2/2008
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 5  GAD, Panic My stomach was a bit queezy for the first couple days but that's it. After reading all the negative comments I was hesitant to try Cymbalta, in fact I almost didn't take it. But after quite a lot of convincing, I started to take it. I am glad I did because it's really helped me without making me feel less like myself. F 28 2 years
8/7/2008
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 5  Irritable bowel syndrome/depression NONE!!! My doctor prescribed Cymbalta at first for my extreme Irritable Bowel Syndrome. I found it to be a life-saver!! I went from being able to eat practically nothing without horrible pain to anything, including raw veggies, beans, etc. with NO PAIN! I then noticed that I was able to focus on my work much better (also have been diagnosed with ADHD, but was treating previously non-medically with just exercise, healthy diet, adequate sleep, etc.) About 9 months after starting the Cymbalta my father passed away and I became very depressed, so my doctor increased my dosage, which helped in just a couple of weeks. I now stay at 60 mg, b/c it makes me feel so much better. CYMBALTA IS A WONDERFUL Rx TO ME - A LIFESAVER! F 36 2 years
8/13/2008
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 5  Depression & Anxiety None I can pinpoint to the drug. I read a lot before agreeing to take Cymbalta. I held off for several months because of experiences like many mentioned here. I finally felt dealing with the depression was worth the risk. I started on 30mg and have increased to 60mg. Within days I felt the drug work. It has been tremendously helpful with no side effects of any consequence. Maybe some mild neausea, but I'm not even sure the meds was the cause. I do worry about withdrawing. I take other meds that have horror stories (benzos & prozac). But, I'm not sure of the alternative. So far these meds have saved my life, and so far (knock on wood) none have had bad side effects. I didn't go into this lightly, I've done talk therapy as well for many years. I've have good psychiatrists not just GP's. Without the meds I would be house bound at best. Instead I am a CEO of a company. I believe all the horror stories and it's awful. But I think it's important to know that on the other hand, for some of us this F 41 3 months
8/14/2008
 5  for depression and anxiety attacks Some fatigue about an hour after taking it definitely take with food a lot of sweating in the beginnig but went away I feel great at work very happy more optimistic F 37 1 months
8/14/2008

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