CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  anxiety I feel awesomely numb while taking Cymbalta. After only a couple of weeks taking the drug my thoughts improved, anxiety stopped completely, and I could hear what people are saying better. I do notice that my memory is not great and that I love sleep! It definitely got rid of what were hypochondriac-like thoughts, and completely. Sleep is amazing on this stuff. However, I'm scaling back from 60mg for 6 years to 30mg because I do notice my memory is affected. F 39 6 years
60 1X day
9/22/2014
 5  Depression, fatigue, brain fog None that I noticed If you are having major symptoms, do not be afraid to try this drug. Just ramp down from your old medicine if any and ramp up slowly to this one - take a whole week. This medication has quite literally changed my life. I'm a professional and wasn't able to get out of bed before 8, and then I was foggy through about noon ... not good. I would sleep 12 hours sometimes and still have these issues. I am now sleeping normally, 8 hours or maybe 7 at times. I feel wonderful in the mornings now and can immediately get up and start my day without the fog. I have energy and am enjoying my interests and activities again. I don't know if I'm having loss of appetite or weight loss quite yet, but I will say that previous to taking Cymbalta, I ate to wake up or clear my head and feel better. That's no longer happening and I'm back to riding my bike, gardening and other activities. So I won't be surprised to lose a few pounds due to my decreased need to consume calories and my increased caloric burn. I'm impressed -- in my 15 years of having periodic episodes of depression, I've never had such a drastic turnaround. Give this drug a shot -- if it doesn't work for you, ramp down slowly and move on. Nothing to lose and a lot to gain here. F 43 12 days
60 mg 1X day
9/1/2014
 5  neuropathic pain Biting myself when chewing Numbs the pain just enough so that I can handle it with no problems at all. F 60 3 years
60mg 1X day
8/15/2014
 5  Fibromyalgia 1st couple of weeks there was nausea and insomnia; also a bit dizziness right after taking, also experience extreme fatigue mid day. Eventually all passed and an added bonus is how much happier I am! F 60 4 months
60
12/17/2014
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 5  major depression No side effects. Now that I've just finished tapering off after 4 years of use, I'm experiencing some light-headedness/dizziness, fuzzy-thinking & nausea. This medicine saved my life. F 28 4 years
11/15/2009
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 5  depression, hypothyroidism Nothing major. I upped the dose after one week instead of two. A little trouble sleeping, but since I have major fatigue, that is fine with me. I am much more awake in the mornings. Feeling great, no depression symptoms in switching over from Lexapro/Wellbutrin. I think a lot of the "side effects" people are listing are symptoms of their medical conditions and not this drug.It is treating my depression fine, with hardly any side effects. Also, I have a back injury which causes chronic mild pain, and it is feeling a lot better. I can stretch further than I used to be able to without the pain. Seems like an appetite suppressant to me. Hardly hungry at all. F 38 4 weeks
11/9/2009
 5  Fibrymyalgia, depression, anxiety I've had some brain fog. Searching for words when I'm talking and I can't seem to come up with the right one; I've been bumped to 90mg and fee better than I have in years. I call it the greatest thing that's happened to me. I can function like a human being. F 58 1.5 years
11/23/2009
 5  Fibromyalgia & depression I have not noticed any side effects that I can necessarily contribute to the Cymbalta. WOW!!! I was told about this medication by my beautician, who suffers from fibromyalgia & depression. She said she felt like a totally new person, and that I should at least give it a try. I have been suffering from fybromyalgia & depression for several years. I asked my Dr to prescribe it, I tried it...and she's absolutely right...it makes you feel like a human being again!! Please don't let the negative remarks left by others, keep you from at least trying this medication...I'm glad I tried it! I feel so much better! Please realize, nothing is a miracle drug...but you certainly can feel good enough to function in life again! F 58 2 months
12/1/2009
 5  Fibromyalgia Sweating - couldn't exercise at all because the smallest effort left me drenched and unable to cool down. I have other symptoms such as wieght gain, indigestion, what someone else called brain zap but I take other medications and can't be sure which causes them. My doc didn't correlate the excessive sweating to the Cymbalta for a long time. I does control my fibromyalgia. I am supposed to be at 120 mgs, 60 twice a day. I am currently on 90 due to my insurance having limits on how many pills they will allow. 90 doesn't work as well but it's better than 60. I've tried Effexor but it affected my sleep. I used to be on nortriptylene for a long time. When it became ineffective, I switched to cymbalta. I don't know what I am going to do if I am no longer able to get it. I am very sensitive to sleep problems - vivid dreams. F 51 5 years
11/30/2009
 5  migraines No side effects, unless you can consider feeling awesome a side effect... I tried Paxil and Amiltryptaline (sp)for my migraines, and even tried inderal. My neurologist suggested Cymbalta over and over again and I kept refusing it because of the cost. Once I got my prescription deductable met, I gave in. Got a lot of samples, and after two and a half weeks, I feel fantastic! I was dealing with an addiction to opiates and with prayer for a miracle, which as it turns out was in the form of Cymbalta, I am over it! Today, I realized that I am ready to quit smoking. F 42 18 days
12/9/2009
 5  Fibromalgya/Scholiosis/back problem I, think cymbalta is a real good medicine. But maybe will not work the same for everybody. In my case, i have been taking cymbalta for almost one year, i suffer from scholiosis that become in a hard fibromalgya pain. I have been feeling almost completely relieved from the pain i suffer during more than 5 years. I couldn't walk well, carryng my babies and I suffer from pain 24 hours per day, i wanted to die, since i begin taking cymbalta i have improve my quality of life, i feel almost normal. But i worried about side effects. My doctor prescribe to take 60 mg daily until 1 year, however i didn't follow up, the first 3 months i take daily, then 3 or days per week, now just maybe 1 or twice per week, (depending on how i feel), i feel better and better, and what i think is the side effects just appears when you take it daily. I just take when i need and i have been doing that for one year. Right now i feel great, and i have recover my life. During five years i taked a lot of drugs, a F 32 10 months
12/18/2009
 5  Major Depressive, Bipolar, Anxiety Muscle Aches/Spasms, Fatigue, Acute Insomnia, Mild Constipation, Increased Libido, Yawning, Severe Nausea and lightheadedness (if taken without food), Decreased Appetite, Weight Loss, Mild Dizziness and Vision issues, and initial diarrhea This has honestly and seriously been a mircale drug for me, my side effects have all been very mild to almost non existant other than the yawning and fatigue, but though my body feels tired I can finally get up and motivate myself to do housework or anything that I used to find so demanding and draining. I am finally happy and no longer have suicidal thoughts or urges. I have lost weight and feel good about myself and abilities. I can socialize withou have panic attacks. I LOVE IT. And I'm only taking 60mg. It's fantastic. F 20 4 years
12/23/2009
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 5  Fibromyalgia I had an little dizzy when I first started, I have changed taking my cymbalt to night before bed and works great. My only complaint is the price. My insurance only covers $30 of the price. wish to find a way to reduce the cost. I have started my second month and I have noticed so much better feeling. The pain I have experience has dramatically decreased. I am able to walk more freely. I also have arthritis, but am able to handle it better. Alot better mood without the pain F 53 45 days
12/5/2009
 5  Anxiety/Depression The side effects I have experienced in my first week on Cymbalta are dry mouth, constipation, and lack of appetite. I was given Reglan and Benadryl six months ago in the emergency room for a migraine that had been ongoing for three days. In a matter of seconds, I became so anxious that I wanted to leap out of the hospital bed and run out of the ER. I told the nurse and she said that was a "normal" reaction. It was so severe I couldn't hold my head still for the CT Scan. Within a few days of leaving the hospital I began having panic attacks, which is extremely uncharacteristic for me. The panic attacks led to a truly debilitating depression, which is the polar opposite of my personality. Since then I've learned that the Reglan could have been the culprit and I have tried Xanax, Lexapro, Buspar, Trazodone, Prozak, Metoprolol, Ambien, and now Cymbalta. The Cymbalta in the morning (30 mg) and Trazodone at night (50 mg) were a miracle combo that have returned me from an absolutely horrible dark depression. I blame the Reglan for putting me there, and after many trials, I praise the Cymbalta for giving me my life back. F 36 7 days
1/8/2010
 5  Depression Nausea,dry mouth(first few weeks),constipation,skin itching,weight loss,stomach pain. I had started on 30mg of Cymbalta on November 24,2009 and then went up to 60mg a week later. It was perscribed for depression and stomach problems (IBS,Gastritis). At first I had most of the side effects I listed but they gradually decreased. My physician told me to only take this on a full stomach right after my biggest meal of the day. My depression (and anxiety) have decreased quite a bit starting around the 2nd week. I am much happier and relaxed. My blood pressure has gone down as well. So far, I am very pleased, although I do hate taking another prescription med (also take Lipitor, Atenolol,Ambien). This web site has been very helpful and re-assuring to me. Thanks to all for your comments. If you do plan on stopping this medication, please do so gradually and under a doctor's quidance. F 61 7 weeks
1/11/2010
 5  depression and fibromyalgia Initially: heart palpitations, teeth grinding, diarrhea, decreased appetite, emotional flatness, decreased sex drive, night sweats, vivid dreams. After taking Cymbalta for 18 months, however, my side effects now are: night sweats, vivid dreams, and constipation The side effects were difficult to tolerate at first, but the difference in my mood and pain level made them bearable. Within 2 days of starting the drug, my depression and pain resolved. Cymbalta changed my life. I went from suicidal and unable to exercise to depression-free and physically active. F 47 18 months
1/18/2010
 5  Depression/PostPartum Depression The only side-effects are when I tried to come off or miss a pill: SEVERE headache with nausea/vomiting worked very well and started working much quicker than other med did after first pregnancy. My only concern is that it is so hard to come off of, I've tried several times with no luck. F 30 5.5 years
12/29/2009
 5  depression ringing in my ears, no libido (but is that my age?) I am very happy with Cymbalta. It has given me the least side effects of all meds I've tried; Welbutrin, Lexapro, Celexa, and Zoloft. This was the first Christmas is many years that I welcomed. I have pleanty of energy, creativity, I can laugh, I can cry. I take 60 mg, and it's a comfortable amount. I would like to cut back to 30 to see if the ear ringing subsides, but am feeling so good I hesitate to rock the boat. F 56 8 months
12/30/2009
 5  Depression,Anxiety,Fibromyalgia Feeling tired I have tried cymbalta before but stopped it b/c I was in a relationship and I was unable to orgasm during sex. I am now out of my 2nd serious relationship of my life and was having a breakdown. I was shaking, not eating, took 2 weeks off work, was nauseated, and unable to get out of bed or function. Cymbalta in my system for 2 weeks gave me the energy I needed to function again, reduced my anxiety, stopped the shaking, and greatly reduced muscle pain. The depression has decreased. F 35 6 weeks
12/31/2009
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 5  Depression I have not noticed any side effects and I have been on Cymbalta for about a year or more. I have Fibromyalgia also, but never noticed any improvement with the pain. For those of you that are wanting to stop taking Cymbalta, NEVER quit a medication cold turkey. Get instructions from your pharmacist or your doctor on how to take yourself off a medication. F 64 1 years
10/29/2009

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