CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Mood Stabilizer Major Diarrhea and nausea, leg cramps, insomnia, Dr. prescribed Klonipin .25mg once a day in evening to help me sleep. i cut that in half at .125mg and it takes the edge off and I can sleep at night. feeling better in the am. and seems to work. M 47 1 days
30mg 1X day
10/19/2015
 1  Depression chronic pain So so sick. This drug hooks you and makes it impossible to get off. WARNING....DO NOT TAKE THIS MEDICATION. SIDE EFFECTS ON WITHDRAWAL IS HELL ON EARTH M 45 5 years
60mg
11/10/2015
Email
 1  Fibromyalgia Cymbalta is the devil! I tried to get off of it and almost died! Severe nausea room spinning, vivid daytime helucinations. It was like the devil himself crawled into my brain and took it over. Severe rage! suicidal thoughts and actions. Powerful bursts of electricity in your brain. (Brain Zaps) I felt as if the devil took control of me and my body. Horrendous night terrors were I ripped at my skin and torn lesions with my nails. I had to tape mittens on my hands. Nose bleeds. My eyes turned yellow and bloodshot. Vomiting blood/ blood in urine and stool. Violent muscle twitches. Extreme agonizing headaches that would last for days. It got so bad I had to go to the phych ward and call my priest to do an excersim after I tried to blow off my head with a shotgun to make the voices stop. CYMBALTA IS THE SATAN! Please don't take the devils pill these drug doctors are doing the devils work! M 30 1 months
120mg
6/30/2015
 1   I was prescribed this medication to help with my diabetic nerve pain in my feet and some mild anxiety...it took away my nerve pain but replaced it with extreme sweating tingling warm sensations. I went from mild anxiety to extreme panic attacks. Could not feel normal mentally and thought I was going crazy until I realized it was the cymbalta doing it to me! Once stopped it took days to get out of my system before I could feel like myself again but the damage was done for me at work. This medication is DANGEROUS! It almost ruined my career. I dont normaly comment on stuff but I want to warn people of the dangerous reaction they might have to it! M 43
1X day
7/30/2015
 1  For Pain, Anxiety, Depression, Ect. Anger,Rage,Delusions,Brain Zaps,Blackouts, Memory loss, Destroyed Relationship, And a DUI! I was prescribed this horrible drug in hopes of sciatic pain relief, and Anxiety issues. I was told by a Doctor that this is like a wonder drug that helps people in many areas and that works with past addiction issues and severe pain and Anxiety! I was seriously miss informed!It took away my sex life, caused so many problems between my girlfriend and me and wasn't helping in the least with anything at all.It was instead making everything so much worse! So I stopped! I was already having opiate withdrawals and wasn't pleasant to be around. But this evil pill made me even more mean but I had no idea that I was! I forgot so much about this time of my life! But what I do know now is that I'm a single guy who's fighting a DUI but can't remember hardly anything about the insodent! I'm really scared and haven't taken this Evil drug in almost a year. Nobody believes me about this drug because of my past! I don't even remember if I drank that day or not! All I remember about that day is waking up and hitting a mailbox! I found out that they shouldn't have prescribed me those medications together! I have never had a DUI before! I could have hurt someone! How is this drug still legal????? M 44 3 months
2 25 mg pd
7/16/2015
Email
 1  Depression Increased suicidality (leading to hospitalization), extreme fatigue, weight gain, some short term memory loss, sleeping over 14 hours a day M 17 2 months
30
11/19/2019
 1  Depression and anxiety It has added more anxiety and also badly caused severe pain in urinary tract , bad pain in bladder, penis and all muscles whole body. It is very dangerous drug. Side effects are much more than any little benefits . try natural treatments . try omega 3. M 60 1 months
5/15/2019
Email
 1  Neckn pain Very sick and dizzy M 64 2 days
60mg
6/22/2020
 1  Depression / desth My husband before Cymbalta was a smart / strong man who became distorted , weak, nervous , anxious man .. It tore my family apart .. He could not sleep as the dr also gave him Ambien which made things worse .. He had numb feet and they were always freezing , nitemares , doing thing that he would not normally do in previous years .. Cymbalta and Ambien took this mans life and in turn took mine and my family’s , we were married 3.5 years and his mind got so bad he took his own life ! All at the hands of big pharma who didn’t kno who he was . No help except a pill and that is one sad thing to control ones life . M 48 16 months
30/60 MG
4/6/2018
 1  Neuropathy Most of what everyone else has said, anxiety, anxiousness, difficulty urinating, blood in urine, all over body weakness, especially back and upper body, blurry vision, headache, nausea, insomnia, bizarre dreams when I slept, tremor, cough, excessive yawning, no sex drive, no emotions. Didn't work for me for pain, although it does for some, the side effects outweigh its effectiveness. Wouldn't recommend this to anyone. Please don't use antipsychotics if you don't have to. It takes forever to get them out of your system M 54 25 days
60 1X day
3/28/2018
Email
 1  ocd insomnia. speeding. shaking. feeling sick. clamey sweating. weakness. was given to me because i'd tried all other meds. i found this one to be VERY!, powerfull- almost like meth or something... CAN'T be good for your cns. i only lasted 5 days on it. my body HATED!, it. good for folks it helps, but for me- i don't need amphetamine in my life right now. M 48 5 days
30mg 1X day
9/25/2017
 1  yes I was stoned, and did not know what I was doing, or where I was even though I was at home. Just glad that I did not do this on a work day, as I probably would have stopped on a green and gone on the red. I was that wasted. I knew that something was wrong and hate not being in control so I refused to take anymore. Why is this considered a good alternative for pain, when I have no problems with any of the opiates? The only thing that I have had happen with things such as morphine is that it made me a little foggy and tired, but I had my whits about me. Same with Norco, that Kaiser wanted to get me off so bad that they lied about me saying that I wanted norco and nothing else. Even though I had asked for something else that is safer because of the acetaminophen in it and more effective long term against pain. Methadone is safer and yet they do not have it and it is harder to get unless you are previously a drug addict. M 53 1 days
20mg 1X day
12/24/2018
 1  Chronic pain & emotional tension Horrible! Waking in night and making incoherent phone calls to friends, halucinations (more severe & disturbing than LSD- being honest), disoriention.... One drug that Health Canada MUST pull! Please report ANY side effects promptly to your Dr. Lilly & Health Canada! Just don't take this please! M 59 2 months
6/10/2017
Email
 1  Pain Management and Anxiety It immediately caused severe​ problems with concentration, blurred vision, upset stomach, and angry mood swings. It also caused problems with total lack of sex drive and caused overwhelming emotional problems. What makes this medication so bad is the 12-hour half life which I am sure you will read plenty of posts about. I hate this drug and anyone who prescribes it because they obviously haven't read any of the patient reviews. It looks like half of the people that take it have problems and the manufacturer failed to devise a plan to come off this medication. Also the manufacturer does not require the prescribing physician to advise the patient of the guaranteed side effects and addictive properties of this medication. This junk may have cost me my jo. Fortunately I can see a little bit of difference one week after discontinuing use. I will be calling a lawyer. No wonder the FDA did not approve their new drug for 2017 for Eli Lilly who invented Cymbalta and heavily advertised the drug without disclosing accurate side affects and withdrawal syndrome for people like me that had a bad encounter with this "medication". I would love to see all of the management for Eli Lilly forced to take this medication as they have advertised for a year and then cut them off completely so they will learn the real side effects of this drug that they so heavily advertised. I would pay good money to watch each person's life fall apart in front of their eyes. Whatever happened to the code of ethics that the scientists and doctors that work at Eli Lilly. I also have a real problem with the way this medication was dispensed at my Pharmacy and how there were none of the required FDA warnings on the any of the bottles that I was prescribed. What is wrong with doctors in America today. I tried to tell my doc M 50 2 months
4/21/2017
 1  anxiety and arthritis Constant nausea from day one. Could not tolerate this medicine. M 65 10 days
20 2X day
9/13/2019
 1  Depression / Anxiety Worked well to decrease depression and helped level me out. But after a few years of taking it, I am realizing that I have changed a lot (not sure how much is due to the medicine or just life changes) My memory is foggy. Can't remember details of events or movies I saw last month. When I miss a dose I get dizzy and the terrible brain zaps. It's so distracting I can hardly make it through a day of work like that. I would not recommend this drug to anyone, as the long term effects (and pain in the butt withdrawal symptoms) may be very severe. M 24 4 years
60 mg 1X day
1/30/2017
 1  Chronic pain Upon attempting to stop med had severe issues for month and half. Not sure how well it actually worked after using for 6 months. Used for chronic pain related to C2-T1 lamenectomy and fusion. Stopping drug was debilitating due to brain zaps and vertigo which led to nausea and inability to function. I would never take this drug again as withdrawal (yes withdrawal) is horrible and lasts for months. I tried to wean off it as doctor recommended. Even went so far as opening pills and removing half the med. Would never recommend due to issues with stopping medicine. Think long and hard about taking this med. Brain zaps are truly debilitating and should be included in disclosure as can last months. M 64 6 months
30 2X day
6/20/2022
 1  Depression Horrendous nausea episodes with pressure in the head and muscle tremors M 44 0 days
30mg 1X day
5/10/2022
 1  Anxiety, depression Memory loss, brain fog (for the very things I can recall), aggression, suicidal thoughts, depression This medication has been the ruin of my life. Will probably spend the rest of my life in prison. Be wary of ANY medical professional that trivializes concerns you have regarding the medication. M 49 21 days
60 1X day
2/21/2022
Email
 1  Depression Headaches, sore neck, suicide thoughts THIS DRUG IS DANGEROUS. I took this drug in the morning and after 2 hours I had severe headaches and stiff neck. I rarely get headaches. After another 2 hours I couldn't talk and had to leave work. Driving home I had severe suicide thoughts. Was thinking I would drive out onto the highway and drive in front of a truck. Thankfully my home is only 3 min from work and is between the highway and work and I was able to make it home. This is the only time I have had suicide thoughts in my life. M 62 1 days
40 1X day
10/27/2021

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