CYMBALTA Reviews (DULOXETINE)Average Rating: 2.7 (2745 Ratings)Filter ResultsCompare CYMBALTA with similar:
Type: Rx Drug
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Results are sorted by Gender males first. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 |
More on CYMBALTA: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR CYMBALTA | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 1 | Depression | None at all. | I didn't notice any effects at all. I also know a number of other people who have also been recently prescribed Cymbalta and they have told me they have had no effect. This seems to me like a pointless drug that is currently being heavily prescribed because it was recently approved. But if it helps some people, great. | M | 30 | 2 months | 3/19/2007 | 1 | Generalized Anxiety Disorder | Nausea, depression, night sweats, excess sleep, panic attacks, severe anxiety, general inability to function followed by negative personality changes that friends and loved ones noticed after a few days. | My psychiatrist and MD both wanted to get me off of xanax because of habituation and dosage creep, I'm up to 4mg+ per day after 3 years of using it. FDA recently approved Cymbalta for GAD so my MD put me on a 30mg trial dose to see how I handled it, along with my (habituated) xanax dose. The idea was to let the Cymbalta do it's thing for a while then taper off the xanax. The result was an abject disaster on every possible level. I don't suffer from depression, and I'm glad that this helps people who do. The side effects were far worse and much broader than described in their clinical trials. Basically, the first few days I felt extremely toxic physically, then when the brain chemistry changes started to kick in, my anxiety level was off the hook to the point of nearly complete dysfunction. I lost a week of my life to this stuff, just two weeks after it was officially approved by the FDA for exactly the problem I have - GAD. I've been off it for two days now and I finally feel li | M | 44 | 7 days | 3/11/2007 | 1 | PTSD, insomnia | While on the drug: 25lb weight gain, insomnia, sleep myoclonus, akathisia, RLS, anxiety, mania (inability to concentrate, racing thoughts), painful muscle spasms (paricularly in piriformis, causing severe sciatica), paresthesia, constant diarrhea, pounding heart. After slowly taping off drug over 6 weeks - SEVERE DRUG WITHDRAWAL. Intermittent but severe "brain shivers", vivid horrific nightmares, severe muscle spasms and cramps (some causing excrutiating sciatica), worse akathisia, worse paresthesia, hypermania. | Was switched to Cymbalta from Zoloft which had same side effects but worse. All the manic side effects had to be countered with an anti-anxiety medication (Xanax). While taking Cymbalta, Ambien no longer worked for insomnia, had to be switched to Seroquel which helped insomnia but then I was a zombie 24/7. Have found out that I may have permanent brain damage from taking Cymbalta (inability to make any serotonin). Would reserve this drug for only my worst enemies. | M | 53 | 9 months | 11/1/2005 | 1 | Neuropathy | Wired or Tired depending on dose. Lightheadeness, dizziness. Extremely high blood pressure upon discontinuation. | Duloxetine (brand name cymbalta) causes autonomic and endocrine changes due to the reuptake inhibition of norepinepherine. Upon cessation of the drug it causes autonomic disregulation do to the extreme decrease of norepinepherine on the 5-HT neurotransmitter. Since cymbalta has an extremely short half life it can make you extremly sick upon cessation. If necessary for MDD (major deppresive disorder) take a non-SSNRI tricylic, though they can have the same side effects. 99% of doctors are unaware of the autonomic disturbances caused by duloxetine, and 100% of the Eli Lilly reps have no inkling of it. | M | 29 | 7 months | 11/4/2006 | 1 | Fibromyalgia | Well I was talked into this after a year of trying something else. Read my comments and others comments. Right now, symptoms include severe night sweats, vivid dreams/nightmares, severe dizziness, stuffy head/achy/fever, chills, etc. Sometimes cannot stand and/or walk. I was grinding my teeth before this; much worse now that I'm not it. RICO and/or other class action lawsuit is in order here! Stop the ride, I want off! | I was diagnosed with fybromyalgia last year and tried an experimental dosage of pregabalin (if I spelled that right). After the trial, I tried a regular dose of Pregabalin. It helped with some of the pain, but still felt like it was missing something. I was told about a Cymbalta trial, so I waited 30 days from the end of the other pills and started the trial. I only lasted a few days on this trial; the pills were MURDER on my stomach. Then I was given a 20mg dose to start; increasing to 2-20mg pills when I could tolerate it. I had a few odd aches and pains about a month into the Cymbalta, and a little sleeping difficulty. I was also afraid to take them on an empty stomach, so usually took them with food around 4pm (my wife and I are both full time students and we eat that meal before classes every day). | M | 40 | 5 weeks | 11/2/2006 | 1 | Fibromyalgia | Well I was talked into this after a year of trying something else. Read my comments and others comments. Right now, symptoms include severe night sweats, vivid dreams/nightmares, severe dizziness, stuffy head/achy/fever, chills, etc. Sometimes cannot stand and/or walk. I was grinding my teeth before this; much worse now that I'm not it. RICO and/or other class action lawsuit is in order here! Stop the ride, I want off! | This week though, I had the MONSTER of headaches and stuffiness out of nowhere. Monday I was starting to feel foggy; couldn't complete simple experiments in school. Tuesday morning my head was swimming so bad I couldn't even walk. Head was stuffy, throat dry, chills, fever, it was bad. aches and pains were worse than what they previously were; back/neck were killing me besides my head throbbing. I skipped my dose Tuesday and Wednesday, then took it as early as I could this morning. I was having terrible night sweats; getting up twice at night to change clothes and go to the bathroom. I'd get the shakes/cold trembling out of nowhere. Even at times during the day I'd sweat profusely then stop. It was almost like my hypothallamus intermittently lost control of my bodily temperature. | M | 40 | 5 weeks | 11/2/2006 | 1 | Fibromyalgia | Well I was talked into this after a year of trying something else. Read my comments and others comments. Right now, symptoms include severe night sweats, vivid dreams/nightmares, severe dizziness, stuffy head/achy/fever, chills, etc. Sometimes cannot stand and/or walk. I was grinding my teeth before this; much worse now that I'm not it. RICO and/or other class action lawsuit is in order here! Stop the ride, I want off! | I emailed the doctor, and am awaiting instructions. I would think it was all the Cymbalta EXCEPT that my wife has a few odd aches and pains too. Now, if Cymbalta is causing some sort of weakness in my immune system that ALLOWS normally weak viruses to grow, that could be a problem. Our bodies could normally encounter thousands of viruses and we'd never know it. But it could be that Cymbalta enables certain, normally ineffective viruses to take hold in our bodies or mutate into something that can affect normal, healthy people. I don't know. Things may change when I go to the 60mg dose here in a few days. I'm not sure. But seeing what other people have been saying for side-effects, I'd have to agree with most of them. I can't attribute all the symptoms to Cymbalta, nor can I say which ones are truly sickness related or which ones are purely Cymbalta. But I will say that I DO seem to have gotten 'sick' twice now in a relatively short time, which NEVER happens with me. And my | M | 40 | 5 weeks | 11/2/2006 | 1 | depression | flu-like symptoms, body aches, nausea, extreme fatigue, dry mouth (60 mg), couldn't function and do basic living | Weaning is a nightmare, please read up on internet about weaning. One Psychiatrist only puts a person on if they are to be on for life as the weaning is awful. I am still going through it after 1 month (9 days completely off). | M | 16 | 2 months | 5/1/2007 | 1 | anxiety | I had an immediate and severe reaction to this drug. I had hot flashes, I felt disoriented, ended up having a serious panic attack and had to go to the hospital. | I have read that this is a common reaction to Cymbalta with a first dose. My (old) doctor thought that it was because the dose was too high for a first go at it and tried to talk me into taking it in microdoses until I adapted to it. Given that my experience was extreme and frightning, I told her she was kidding herself! | M | 38 | 1 days | 3/29/2007 | 1 | Treatment Resistnt Major Depression | Did nothing for me. Absolutely Nothing. | Have tried all of the SSRI's and SNRI's to no effect. Been depressed for 4 years. The only thing that has helped is a recent switch to a tricyclic antidepressant imipramine. | M | 49 | 120 days | 3/24/2007 | 1 | DEPRESSION/FIBROMYALGIA | WEIRED FEELING IN HEAD , FORGETFULLNESS /SPACEY/UNABLE TO CONSENTRATE VERY SCARY FEELING.CONFUSED | THIS DRUG IS NOT ONE THAT I WOULD RECOMMEND TO ANYONE.I HAVE BEEN ON ZOLOFT 100MG FOR 8 YRS AND WAS SWITCHED TO CYMBALTA 60MG.AFTER ABOUT FIVE WEEKS I WOULD GET THIS SPACEY FEELING, UNFOCUSABLE (IF THATS A WORD) BUT THAT IS HOW I FELT.THE DR TOLD ME TO TAKE 30 MG FOR ABOUT 4 DAYS THEN STOP ALL TOGATHER , OH I THINK THAT WAS A MISTAKE.I AM AFRAID TO DRIVE I FEEL THAT MY VISION IS OFF VERY SPACEY.I HAD A MRI / MRA DONE LAST WEEK BECAUSE I WAS NOT SURE WHAT WAS WRONG BUT READING THIS BLOG IT HAS TO BE THE MEDS.I WENT TO A NEUROLOGIST YESTERDAY TOLD HIM WAS COMING OF CYMBALTA AND HE SEEMS TO THINK IT IS THE WITHDRAWLS FROM THIS MED HE TOLD ME NOT TO USE ANY ANTIDEPRESSENTS FOR A WHILE UNTIL I CAN GET THAT WEIRED FEELING GONE.I WAS VERY CONFUSED FEELING TRYING TO WORK THIS WAS VERY HARD BECAUSE I COULDN'T REMEMBER WHAT I WAS SUPPOSE TO BE DOING.THIS DRUG NEEDS TO BE REEXAMINED.09/28/06 | M | 35 | 45 years | 9/29/2006 | 1 | mild depression & anxiety | Dizzy, nauseous, sweating, anxiety, uneasiness, restlessness, shivers, | Over the last 14 years I have taken many antidepressants and have never experienced anything like this. I was give a doctors sample for 60mg which was probably too high to start out as most seem to start with 30mg. I took it this morning at 8am and by 10 I was feeling off, by 1pm I had to go home. I could not explain the experience I was having to my wife. Finally at 3pm I realized that this was the closest I've felt to doing LSD (yes I do know). Unfortunately, all the similar symptoms were the bad ones. It is now 12 hours later and it still feels like LSD but I'm getting more flu like symptoms now. Seriously, I was hesitant to take this drug when I was reading some articles last night but I decided to do it anyways. I found this page just now and after reading many comments I had to post my own. Nothing that makes me feel like this could end up doing me any good.I do not envy those who want to come off this drug but are afraid to. | M | 35 | 1 times | 10/7/2008 | 1 | depression | My husband's suicide read, "sue Cymbalta, seritonin syndrome." | M | 59 | 10 days | 2/2/2007 | 1 | Peripheral neuropathy; SCI | Severe headaches, dizziness, nausea, vomiting. Night sweats so bad I had to sleep with a towel. Insomnia - maybe due to waking up in puddles of sweat. Never felt well enough to think of sex - I hope everything still works. Quit cold turkey last week and am still experiencing withdrawal effects. This is BAD medicine. | This dangerous drug needs to go back to the FDA for more study. I've been bedridden for the last 2 weeks because of the severe flu-like symptoms it causes. Never noticed any reduction in my pain level. After reading this forum I wonder why Cymbalta should ever have been prescribed for pain. | M | 57 | 13 days | 8/2/2006 | 1 | RSD/CPRS nerve pain | Felt like I was extremly drunk and sick to my stomach. Headache lasted the whole time. Stiff neck and muscles. Had bad dreams and started to panic because of the way this drug made me feel. This drug needs to be studied more. Be careful when taking this drug. I called my pain mangament doctor who gave me this drug. He said he didn't know that this drug had that many side effects. Was told by Lilly that this drug had hardly any side effects and is the best on the market. So watch out. | This did help me alot with my RSD but it's not worth the side effects I had to go though. | M | 29 | 2 days | 8/8/2006 | 1 | depression, anxiety | I wrote a few days ago. Cymbalta kept me from having panic attacks, helped me sleep (too much!), and helped with anxiety. However, I know my body and I just kept getting the feeling that it was not good for me physically. Headaches, then visual disturbances (slight delay, like when you have a concussion). I feel better off the medicine. | I think this is a dangerous drug, affecting everything from digestion to circulation. Visual disturbances and lightheadednessare finally gone now that I am off, but headaches come and go. When I exert myself physically doing yard work or working out in the gym my head sometimes pounds and feels like it's going to explode. I hope this is not a permanent change!!! | M | 57 | 5 months | 4/16/2007 | 1 | depression/anxiety/nerve pain | tiredness, brain zaps/electrical explosions in my head, poor sleep, night sweats, agitation, severe mood swings and weight gain. | I've been 'getting off' this horrible medication for a month and the withdrawal symptoms are as bad now as when I began. The brain zaps are the worst of all and I can't sleep. I'm exhausted all day, can't concentrate, my ability to think is impaired and my mind feels as if it's bogged down. I'd been on this medication for two years and then one day it crapped out and all of the depression symptoms returned with a vengeance. The Cymbalta simply stopped working for me. I warn anyone who's considering taking this medication to seriously consider the withdrawal symptoms they'll face when getting off of it, and the day will come. | M | 59 | 2 years | 1/29/2007 | 1 | Depression, anxiety/panic attacks | Flat of affect. Loss of libido. Anorgasmic. Dizziness. Negative dreams. | Cymbalta is NOT for me. I felt like I was looking through a thick mask (disassocation). Made driving difficult (lowered response time dramatically). One day a person cut in front of me in line at a grocery store, and I imagined myself severing his head with a wire like they do in the movies. Seemed like a good idea at the time. This is NOT an appropriate reaction. The thought was completely without emotion and scared the crap out of me later as I looked back on the event. I'll never take Cymbalta again. Taper? You kidding??? I dropped that stuff like a burning rag even though the two weeks of discontinuation syndrome was awful. | M | 50 | 3 weeks | 7/9/2007 | 1 | Depression | Terrible nightmares; zombie effect; sexual dysfunction; tremors; slurred speech; apathy | M | 47 | 6 weeks | 7/4/2007 | 1 | pain and numbness in leg(s) | Was taking 30 mg once a day. A definite decrease in sexual drive (thought i was coming down with Erectile Dysfunction). Much fatigue and some confusion. | This drug had absolutely no effect on my pain whatsoever. If anything, it added more problems. New doctor suggested taking 60 mg a day for pain and gave me samples (as my coverage went sky-high on "brand-name drugs). I did not mention the lack of sexual drive because I wasn't sure if it WAS from Cymbalta. I had been weening myself off this drug when I went to her, and my sex drive IS improving. I have not yet started the 60 mg a day and hesitate to do so. I will have to tell her on my next appointment. Meanwhile, I try not to stand or walk too long to avoid the pain. | M | 58 | 2 years | 6/8/2007 |