CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender males first.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  anxiety None that I noticed. I went through quite a few medications over the past 20 years or so and nothing really helped. Now I feel like my old self again. I have confidence. Stuff doesn't bother me like it did. M 57 6 months
60mg 1X day
4/23/2010
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 5  Chronic pain, anxiety Night sweats, insomnia, constipation After suffering from several herniated discs in my neck and spending over a year living on narcotic pain relievers, I began suffering from anxiety. My doc prescribed Cymbalta and told me it would also help with the chronic pain. At first the only side effect I had was the night sweats. I had surgery for the discs and wanted off the Cymbalta because I was no longer on the pain meds. My doctor advised against it but I weaned myself off anyway. Did not have any problems weaning myself off although I had run out at an earlier point and had a severe anxiety attack. I weaned myself off very slowly. Night sweats and insomnia disappeared but my neck pain returned within days. I had lost my insurance and could no longer affford the Cymbalta but I was able to get assistance through LilyCares and made the decision to go back on the Cymbalta for the pain. It is worth the side effects to me. I have found that taking fiber helps with the constipation although I take double the suggested dose. Have not found anything to help with the night sweats. I have tried several things to help with the insomnia but no luck so far. I am considering cutting my Cymbalta back to every other day to see how that works. M 42 1.5 years
60mg 1X day
6/19/2010
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 5  Severe Depression Dry skin, dry/cracked lips, hair loss decreased libido with difficult climax. I was falling deep into depression and was suicidal after a separation and immediately noticed a change within the first few hours after taking my first dose. This medication not only gave me my life back but showed me what I had been missing my whole life. I have several food allergies and many of them affect my mood. I was very unsure at first but now I realize it was the best thing I could have done at the time. without it i could have hurt myself or someone else. Be very careful with taking doses regularly because the side affects are severe. I was unable to take mine for days and was very frightened (something very wrong)the whole time without it especially when trying to sleep. This is a powerful drug and not for everyone but in my case it worked like a miracle. My family is in health care and I was raised learning about medicine. My feelings are that this drug is a double sided sword. The side affects can be controlled if you are careful and smart. If you will be gone TAKE EXTRA WITH YOU and have more just in case you run out. My lips were dry for a year after taking it. Sometimes less is better I have read. M 32 6 months
25mg /50 2X day
6/27/2010
 5  depression and anxiety initially, had stomach pains and some tiredness. some sexual side effects, constipation. this is my second pass at cymbalta. the first time, the side effects were more severe and included brain zaps and a feeling of being amped up. now, after being on it for 4 months, this second time is so much better. i don't have any of the brain zaps anymore and i don't get tired or to amped up. i take it in the early evening as i find this works best for my system. i have had two long lasting side effects. the first is constipation. i now take benefiber three times a day and this really helps out tremendously. just with each meal. benefiber comes in "to go" packages so it's easy when i go traveling or eat out. the second side effect is the sexual one. although i do have the desire and can achieve an erection, it is difficult for me to orgasm. i used to be able to do it easily but now, it takes real effort and all the planets have to be aligned, if you catch my drift. also, the amount of semen that comes out has diminished. i try to reach orgasm, but if i don't, i am not discouraged, and maybe that is the cymbalta working to not make me depressed, i'm not sure. PLEASE, if you are a male and have had similar experiences, please contact me, i'd like to discuss this with someone who has the same side effects as me and find out possible solutions, etc. overall, i really do like cymbalta and don't see myself getting off of it any time soon. M 41 3 months
30mg 1X day
7/16/2010
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 5  depression ocd little tired, slow weight Gain. I was on concerta for ADD when a counselor recommended Cymbalta. This med has really helped with my mood swings, my anxiety, and every other negative aspect of my personality. I am a little concerned about the weight gain but it may be due to the discontinuance of the Concerta. M 43 15 days
60 mg 1X day
8/1/2010
 5  Depression, anxiety, insomnia First few months dramatic decrease in sex drive and ability to have orgasm and ejaculation. Worked like a truth drug telling people exactly what I thought about them and everything else but very calmly and to the point. Increased desire to consume alcohol. No other side effects and the sex drive/performance issues leveled out to normal after a few months. The blatant honesty side effect was surprising at work, home, and with friends but was liberating for me personally. Way more social and easily engaged in conversation with friends and total strangers. Discontinuing this drug has been a big challenge for the past month. This is the worst side effect of all since life was really good while I was taking it. M 47 1.5 years
30 mg 1X day
8/28/2010
 5  Borderline Personality Disorder First week I felt "hungover," but that went away. Now I have occasional insomnia and feelings of being "hyper" or having excessive energy. I seem to be a little more spacey or forgetful of minor things in the short-term. Definite sexual side effects. I've been on almost every other Anti-Depressant on the market and Cymbalta is the only one that has brought me relief from depression and self-harm impulses associated with BPD. M 29 2 months
60 1X day
9/12/2010
 5  OCD, depression. dizziness, slight delayed eiaculation. Cymbalta is saving my life. it controls my OCD in a way that i do not think about. it is very useful in depression, attention and especially in GAD too. Give it a try. I take it with Zyprexa Zydis 2,5 mg in augmentation. M 24 1 months
120 mg 1X day
11/29/2010
 5  Major Depression and Anxiety I felt a little nauseated for a day or 2.. other than that I can't even tell im on a AD! Amazing. Negative thoughts disapeared within ONE day of 30mg. Since then I have improved 100%. Miracle drug for me. I am lucky enough not to have any side affects from the drug yet. Standard SSRI's gave me terrible side affects, and a wierd feeling in the head, I can't even tell im taking a drug! M 26
60 1X day
12/21/2010
 5  interstitial cystitis, depression Tired, tinnitus, restless legs. I started taking Cymbalta for depression and also pain from interstitial cystitis and vulvodynia. Since I am very sensitive to meds, I started by opening the capsule and pouring most of the pellets out, recapping it, and taking the small amount left. I gradually worked up to 30 mg a day. I felt instantly calmer from Day 1, and had improvement of bladder urgency/frequency/spasm. I have since reduced dose to 20 mg per day. I initially had exacerbation of restless legs, which went away over time as I adjusted to Cymbalta. I can get tired and spacey in the afternoon when it kicks in, but I gladly take the med because it has given me my life back. M 54 2.5 years
20 to 30 1X day
1/25/2011
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 5  depression I have had muscle aches, especially in my arms. However it is the best that I have ever had for my depression, I don't feel like I'm in a fog, I lost my youngest son 3 years ago and if I had not been on my Cymbalta I don't know how I would have made it. M 45 4 years
60mg 1X day
3/21/2011
 5  depression and nuerophophy none M 65 155 years
60mg 1X day
8/14/2011
 5  depression anxiety none excellent med M 45 1 months
30 1X day
9/29/2011
 5  Depression, weight control and pain Im a jockey I've had severe falls and a life time of weight problems to stay in racing that has caused me some very deppressing actions and thoughts since I've been these pills I've never been to happy in the mornings to b at track work nor at loosing weight to ride raceday but this is by far the best thing I've ever dealt with at the minute. M 24 1 weeks
30
6/1/2012
 5  Anxiety/Depression First three months: Reduced libido, dizzy spells, nausea, hot spells. After three months: hot spells, last longer sexually, don't realize how drunk or full of food you are. If I miss a pill I have insane dreams and some withdrawal. I think going off these meds will be very difficult. This medication has changed my life. My depression and anxiety were at time paralyzing. I now enjoy life! My wife says that I am a changed person and our relationship is 1000% better. I can think clearly and focus more on what is important. I feel like I did 20 years ago! M 38 15 months
120 MG 1X day
12/14/2011
 5  back and nerve pain diarrhea and weight loss has helped m greatly M 43 3 months
30 mg 1X day
12/27/2011
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 5  Anxiety None. Just went from 30mg to 60mg one time daily. This has really helped with my anxiety and racing thoughts. M 38 2 months
60
1/10/2012
 5  depression anxiety nothing no side effects perfect drug for treating anxiety depression better then anafranil tofranil prozac i have tried all M 50 7 years
60mg 1X day
8/18/2013
Email
 5  Depression, GAD, Insomnia -Excessive sweating (improved after time but remained) -Delayed ejaculation (improved after time but remained) -Hand shaking (occasionally) -Excessive Hangover in the morning after drinking alcohol during night Despite its side effects, I find cymbalta the best choice for Depression, Anhedonia and Insomnia due to GAD. My GAD controlled my life since I couldn't handle any stressful situation but thanks to duloxetine I can have a normal life again I enjoy playing videogames/watching movies again. I can go out with friends again without suffering extreme anxiety I can sleep at night easily and naturally Overall it's a very good drug. It only takes 1-2 weeks to work By the way, if you want to quit this med there is only one way: Opening pills and removing a few micro-capsules every 2 weeks (let's say 20 micro-capsules). You won't even notice M 27 6 months
60 MG 1X day
6/25/2012
Email
 5  Depression/anxiety No bad side effects what so ever... Initially I was given Cipralex along with a Ativan to control my initial anxiety due to a horrible gambling addiction I was recovering from which caused me so much pain and suffering I was wishing I would die. I hated my life and what I had done. Although the Cipralex helped me with my anxiety at first, I was sleepy all day, gained almost 30 pounds + my libido was non existent. My doc then gave me Wellbutrin which made me feel better as I lost most of the weight, then headed on 30 mg of Cymbalta gradually increasing into 60 mg. I feel great, I'm able to work 2 jobs + able to be a better father and husband. I hear that the withdrawal symptoms a eye nasty but thus far I have no plans of getting off. I get my blood tested once a month or so to make sure my liver is ok. As matter of fact my doc said that my overall blood work has improved. I've read many horror stories about this med, so I guess it affects people differently. I guess nobody can say if any med is good or not until you try it. M 38 3 months
60 1X day
11/18/2012
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CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

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