KEPPRA Reviews (LEVETIRACETAM)

Average Rating: 2.7 (198 Ratings)

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 ANTICONVULSANTS

 Type: Rx Drug

  

KEPPRA  (LEVETIRACETAM):  Levetiracetam is used with other medications to treat seizures (epilepsy). It belongs to a class of drugs known as anticonvulsants. Levetiracetam may decrease the number of seizures you have.   FDA Approval Date: 1999-11-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR KEPPRACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Epilepsy Dizziness, Confusion, days at a time of severe anxiety. Nausea and vomiting the first week and sometimes now. I'm taking myself off of this medication today. I've been on it for 4 weeks, and have only had a few days of full clarity. I'm fuzzy, anxious, and angry. I cry easily. I've had 3 seizures since I've been on it... one of them today. I have grand mal seizures, have for 12 years. Was unmedicated for a long time because medications kept failing. Now seeing a neurologist,found a brain lesion (unknown what it is or why it's there) which is likely the source in rt temporal lobe. I can't even get back in to see the neurologist for 3 more weeks (his schedule!!) and I can't do this medication that long. I'd rather have seizures than be this miserable all of the time. I normally have auras to warn me before a seizure. Now I always feel like I might have one, because these side effects are so similar to pre-seizure. M 30 4 weeks
250mg
11/20/2015
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 3  epilepsy I didn't relate these problems with the keppra until I read the side effects. I used to have grand mal seizures daily or weekly. Dilation didn't help at all. Keppra stopped the grand mal down to maybe one a month but I shake and twitch non stop and have terrible anxiety, depression and paranoia now. Always picking my skin and face. Head and neck pains daily. I get dizzy a lot and have trouble breathing and get panic attacks about the tiniest things.I don't trust anyone and am very confused and forgetful. The main problem is the anxiety and depression. And panicked feeling. Maybe I should switch meds. I've never had acne before but now I'm so anxious all the time it's all I can do to not scream always picking at my face and smoking too many cigarettes. The anxiety is unbareable. I don't want to be around people, but don't want to be alone. It's weird. I have trouble holding conversations and am snapping and angry on this stuff is there a mood elevator you can take with keppra that can counteract the depression and anxiety? Also I over analyze every single thing and never say what I think anymore because I fear my thoughts are too negative. I need help or something.. F 26 3 years
2000 mg
11/19/2015
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 1  Hiccups, neuropathy Dizziness, headache, sleepiness, confusion, anger, shortness of breath, heart palpitations Horrible, horrible, horrible drug. I don't understand how anyone can tolerate it. It took less than two days to call my neurologist about it. Stay away. F 22 5 days
250mg 1X day
11/9/2015
 1  Seizures- MS Hallucinations- the walls were changing colors; this was described as it was happening in the presence of the prescribing neurologist while in the hospital Caused heart palpitations, raising of BP; multiple panic attacks. Although was Dx'd with MS in '05, these we're my first seizures. This is the worst drug! I was switched to Vimpat, which still had horrible side effects. I have concerns now that these medications caused permanent damage (anxiety, forgetfulness, increased/worsened ADHD symptoms, memory loss). F 45 3 days
1X day
10/25/2015
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 1  Epilepsy Severe mood swings! My mother had her first (and only seizure to my knowledge) 3 days ago and turned blue. After 2 nights in the hospital, they sent her home on this drug and has not been the same since. When someone used to say Kep-Rage, I'd sympathize, but never knew the extent of what they were describing. My mom, generally a positive and humorous person, has been a completely different person since coming home on the drug. She is screaming at my father and I for little reason and staring off into space the next moment. I'm not saying this drug is bad for everyone, but please make sure you're with the person taking it for the first few days to ensure it is not causing an adverse effect. The Neurologist said that on older people, ESPECIALLY, it can cause very poor effects. I'm hoping she returns back to her old self. F 69 2 days
10/20/2015
Email
 2  Seziures I sleep at least 16 hours a day, extremely weak. I want off but dr said no why live if your just sleeping. I'm bipolar it has helped anxiety though. I'd rather have anxiety. I have no life. F 54 3 months
500 mg X 2
10/18/2015
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 4  seizures Weight gain 30 pounds in 4 years F 48 4 years
9/17/2015
 3  Seizure disorder Not helping with my seizure disorder M 14 5 months
3000
8/23/2015
 4  Seizures Weight gain F 36 2 days
1500
8/2/2015
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 1  seizures I had seizures atracks, I have AVM in my brain, which causes these attacks. Doc put me on keppra. I am always tired, weakness, shortness of breath, cannot do anything. Hate this life style. Its the meds making me weak. I am taking one table 500mg, doc told me to take two. With two I can't even move around, so decided to take one. But I don't think it's worth taking this medication. Lots of side effects. My seizures are not very strong, doc told me u can drive. Don't know why he put me on this horrible medication. It is taking my whole life away. Can't do anything, feel like handicap.... F 34 1 months
500mg
6/19/2015
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 4  Epilepsy Tiredness, mood swings. Tiredness has been counterbalanced since i've been taking 300mg lamictal bd. F 29 7 years
1000mg bd
5/13/2015
 1  Brain surgery My husband was on Keppra last year w/brain surgery@500mg twice a day. He was excessively tired & weak the few weeks he was on it. He had chills, a dry mouth, loss of appetite,and sad. We just thought it was the surgery and didn't think anymore of it. Then he was diagnosed with subderal hematomas which had been missed on MRI's and he went in for surgery again. However, this time they put him on 2000mg per day & I noticed rapid changes, that the docs dismissed, such as again, the dry mouth, he said his nose was stuffy, both eyes were red & he kept rubbing his eyes, he got more tired & weak each day, he kept saying he was chilled, his personality started to change, he would get irritable & sad, which is totally unlike him & he kept telling everyone he didn't feel like himself. His gums started to bleed. The docs said, well he's on heparin. I told them he was before & his gums did not bleed. Then his lips got red & swollen & blisters on his lips & in his mouth, he kept saying his back was itchy & would not stop scratching. He had loss of appetite, which even a nurse said wasn't like him since he's on steroids & always makes him hungry. I kept saying I thought he was on too much Keppra. Then one day they were walking him in the hallway and his left side went limp, he wasn't able to talk without slurred speech, the left side of his face dropped by the corner of his mouth & they thought he had a stroke or seizure. His memory was fa They called a resident who decided to increase the Keppra to the maximum dose of 3000mg per day. No one listened to me that it was the Keppra. Then he got worse with his legs jerking as he slept. He got so tired he couldn't keep his eyes open for more than a second. He became hoarse when talking, not only chilled, but was shaking, joint pain in wrist, more depressed, blisters across his cheeks. I mentioned again to the surgeon I thought it was the Keppra & showed how his skin was peeling all over (exfoliative dermatitis) & red bumps. Another physician & RN agreed w/me, so the surgeon said another MRI & CT Scan to be sure, which were clear. The blood work on Keppra came back more than double normal. They decreased the Keppra2000mg in 48 hours & slowly tapered the rest. Even w/him on only 250mg per day, he had aggression, weakness& excessive tiredness. His stomach hurt& he was nauseas& bloated& sneezing & continued chills, they thought he had a cold, he remained in a fog. He had difficulty urinating from the beginning. He's been off Keppra 3 days now, still confusion, memory problems & very tired. He was more clear headed right after surgery, than after the Keppra was increased. We're hoping he does not have permanent damage. All from being on Keppra only 18 days! M 62 2 weeks
1000mg per
4/26/2015
 2  recurrent meningeoma Aggression arguementative weepy emotional mood swings sleeplessness F 10 days
250mg
4/19/2015
 5  Epilepsy Im way different. I feel like i have changed a lot. I got in touch with my feelings, something that i never dealt with, and didnt care to deal with, before the Keppra medication. Also, i get angry really fast but im trying not to show it to people because i know that there is no point in fighting over things that i would normally wouldnt. Moreover, i feel like it takes my energy away from me. I feel that im not me anymore, which makes me unhappy and just want to cry over the great personality i've lost due to the pills. Also, i suffer from migraines from time to time and blurred vision. I also feel that im over-analyzing things and situations in my head. I also experienced mood swings. (i went from extremely angry to super happy in less than 3 minutes two days ago...which is not good...it confuses people!) I take my pills at 8 o'clock in the morning and 8 o'clock at night. Even if i dont know what time it is or i didnt set an alarm o'clock my body (?) feels that its time to take the pill and it usually is 7:50 or 7:55 o'clock (scary)... F 21 1 years
500MG 2X day
4/18/2015
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 2  seizures Rage, joint pain, insomnia, itchy dry skin, trouble walking up or down stairs, dizziness, coordination problems, hand tremor got worse, absolutely no sex drive I was put on keppra after seizures put my in the er. While the seizures have slowed way down (I've only had 2), the absence seizures have gotten worse. My hubby finally had to sit me down and talk to me, the rage was so horrible and I could not let stuff go. I've only been on keppra for a few weeks, but it isn't working well for me. Sure, no seizures, but the side effects are not worth it when there are other meds out there 38 1 months
1000
4/16/2015
 4  Right temporal lobe sclerosis Dizzy, more emotional than usual I had two nocturnal seizures on a vacation. I had just been sleep deprived. I was diagnosed with epilepsy but still haven't got to see a neurologist back home. I think the medication is working but I don't want such a high dose and hate the thought of having to take it forever. I have some confusion but it could also be stress and old age, hard to tell. So far so good. F 37 2 months
1000 mg
4/1/2015
Email
 2  epilepsy Weight gain by 28lbs but I suffer with depression and the main cause of my depression is putting on weight. People are starting to notice the weight gain it's getting me down. I was on topamac 500mgs a day but I was servealy depressed I want to go bk on the topamac but on a lower dose any advice welcome please Making me fat in a word F 34 10 months
750mg
3/22/2015
Email
 1  seizures Lack of concentration, memory issues, sleep issues, depression, confusion etc. Has stopped the seizures but at what cost to me. M 49 5 years
1000 mg
3/9/2015
Email
 1  Seizure I started on Keppra / Levetiracetam in late 2009 after having 2 seizures the latter I broke my arm. Both occasions I was taken to hospital with no recollection of anything for several hours, both seizures happened whilst I was sleeping. After many tests including CT and MRI scans, nothing was found. Soon after I was put on Keppra / Levetiracetam and things seemed ok to start with but not for long my moods were up and down, forgetful, depressed and so on, I hadn't been allowed to drive for a year. With the thought of everything going on in my head, the possibility of not being able to drive I just kept how I was feeling to myself, It was like a ticking time bomb. After almost three years like this I spoke to my doctor, unfortunately I didn't tell him everything just skimming over the surface (I was scared) he put it down to stress and put me on 60mg Duloxotine daily, I was on this for 2 years, this didn't help and made my head feel quite fuzzy, when asked by the doc how I was feeling I just said I was ok even though I wasn't. I am a wreck at the moment. A friend had me make an appointment with the doc this week and also came with me to my appointment, I was in a position there I had to tel the doc everything. I don't know if the issues I have are related to the medication but I wasn't like this until I started taking it. Hoping for some improvements. If you are suffering from what you believe could be side effects from your medication tell your doctor. M 49 5 years
500mg 2X day
1/23/2015
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Patient History
 1  seizure Confused, lightheaded, no memory, loss of finding right word, un-steady, dropping things, forgetful, not thinking straight, achy joints, DEPRESSED, sleeping, tired, groggy, walking like an old man, fuzzy odd feeling in head, can't live this way, ANXIE?TY, painful urination, MAJOR personality changes, Angry, Irritable, changing moods. This is a HORRID drug, my husband is like a monster on this, his doc now has put him on Dilantin and to stay on the Keppra for at least 10 days till bloodwork is done tomorrow. We both got the feeling from the Doc that he won't start weaning him off the Keppra until he sees him on Feb 9th. We CANNOT live this way, he is a clear concise person and we are both at our wits end. He was put on Keppra because he had a really big seizure one afternoon, no history of this before. But he had no water that day, taken other meds, not eaten etc and we feel this more likely caused this seizure. The docs answer was, it would just be better to take these drugs the rest of your life and not have to worry about it WHAT? Really? The EEG was done in the doctor's office, if not performed right it can show all kinds of things. We asked about re-testing and was told we could do that in a year, but again just easier to stay on drugs. Can anyone give us a clear step by step method of weaning off Keppra? He takes 500 mg's AM & PM, so that he can start to see results, we will call the doc too, but do not think we will get a reply and need help now that he that he has been on the Dilantin to get off Keppra. We will also be seeking a second opinion and an EEG performed at the hospital next time, he did have an MRI done as well and it was normal. I simply do not understand why the doc would not be more interested in seeing him off of this, other than a very obvious one. M 66 75 days
1000 2X day
1/18/2015
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