Drug Ratings for PROTONIX

Average Rating: 2.7 (299 Ratings)

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DISORDERS, ACID PEPTIC   

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)   

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    Charts & graphs: Reviews Summary for PROTONIX  | Top 10 Adverse Effects (reported to FDA)

RATING  REASONSIDE EFFECTS FOR PROTONIXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
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 1  Gastritis Foggy Brain, eye pain, vision foggy, severe fatigue, depression, nausea, restless legs, anxiety, nightmares. This drug made me so depressed that I wanted to jump onto the train tracks and end it. I have never been a depressed person but I thought I was dying. By 3 pm I was out for the count every day. Couldn't get off the couch. Dr. sent me for a Cat scan looking for Tumors or Cancer. He couldn't figure it out. All blood/tests came back normal but why was I so sick? Couldn't eat anything but baby food fruit and lost 15 lbs. Stopped the Protonix on my own and started to feel better. F 67
40mg 1X D
9/6/2014

 3  Acid Reflux light headed,anxiety feeling, chest pain, this medicine has helped my stomach pain that was out of control. Now I am having bad leg pain like throbbing, burning very sore and weak. I think I am going to stop taking and see what happens. I was given Famotidine as well to take as a back up for my stomach. F 37 5 months
40mg 1X D
9/5/2014
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 1  Acid Reflux and Esophogeal Spasms I had memory lapses, ear ringing, left eye pain, dizziness, wight gain , but the worst was the head pain. It felt like my head was going to explode! It's been two days since I took the last pill- my choice to go cold turkey. I'm dizzy, woke up from heart racing, and the nightmares are awful. DON'T TAKE. IT! F 62 4 months
40mg
9/1/2014

 3  GERD,BARRETS Brain Fog feel like I'm buzzed, weird headaches, some of the worst that I've had in my life, constant but fluctuate w/sharp stabbing pains that increase the dizziness feeling. Pressure feeling in head and ears like my head is going to explode, ringing in ears, bloated, stomach pain, cramps at lower ribs, weird sensations in my body like a phone is on vibrate, shakiness, anxiety, joint pain, tiredness, you name it I get it. I've am weaning myself off pills, taking 1/2 a pill every other day so far so good. M 44 14 years
40 1X D
8/29/2014
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 1  Gastritis Was given this drug in the Er when I went for abdominal and back pain and was diagnosed with gastritis. They gave me an IV dose before I left and then I took my first oral dose the next morning....with in one hour I started getting severe muscles spasms that are very painful and I could hardly walk. Spasms are from my neck to my toes. So I went back to ER yesterday, they were more concerned about my chest pains so I got a full cardiac work up...after that all came back negative the gave me two doses of Valium to see if that would help. Well it didn't so they gave me some pain meds in my IV...it helped cause I fell asleep lol. Going back to the ER in the morning unless a miracle happens cause I can't handle this anymore F 48 2 days
40
8/16/2014

 1  GERD Severe insomnia, anxiety, panic attacks, blurred vision, racing heart, Sinus/teeth pain, lower back/hip pain, no appetite, drastic weight loss. I was in and out of the ER several times from the side effects of this stuff and no doctor attributed it to protonix! Later read that 1 out of 10 women have SEVERE side effects from this drug. It was the most terrifying thing I have been through. Went off after 6 weeks, cold turkey and had to go thru withdrawals. It has been 7 months since and still dealing with messed up adrenal glands resulting from the side effects. Now going to a naturopath who has me on a good diet - no GERD problems. F 58 45 days
1X D
8/16/2014

 1  GERD Headaches, body aches, fever, insomnia, muscle spasms, severe bloating, constipation, blood in urine, severe cough. This drug put me in the hospital for a day and no one figured out what was wrong. I came home from hospital, looked up severe adverse reactions to protonix, and found out what was wrong with me. I do not know how long it will take me to recover from this. My stomach is so swollen, I cannot eat, I cannot sleep, I cannot quit coughing, my throat is now bleeding, still running a fever, having tachycardia. This is a dangerous drug that apparently most docs aren't aware of the severe reactions some people have!! F 50 35 days
25 mg 1X D
8/5/2014

 1  Gerd/reflux Severe stomach pain, diarrhea, extreme nausea and joint pain. I would rather deal with the Gerd and reflux than take this medicine. Stay away from Protonix!!! F 35 1 days
40mg
7/29/2014

 1  gastritis and Gerd Doctor prescribed for my gastritis and Gerd after the first week or so I felt fine I could eat again although my doctor said I could only take it for 3 months he wanted mere off of it by then. I only made it 5 weeks with it. At first I woke up one night stomach pain n wanting to throw up. Next day I felt dizzy n a drugged feeling. I was burning up but no fever I kept taking my temperature and nothing I thought I was going crazy. I would touch my head n it was on fire I though I was gonna die I was close to going to ER. I put ice on body to some what help. Then I started having insomnia kept waking up at least 4 times every night to go to bathroom and a killer headache that I felt my head was gonna explode. It felt like it was burning the back of my eyes were burning, no tylenol could make it go away I started to feel weak too weak and tired, my bones started hurting I felt naseuas and felt drunk drugged feeling all day my eyes hurt and the light hurt them more my heart was raicing, vivid dreams, and ive lost 9 lbs not happy with that. I felt tingly feeling tru my body and numbness, I really though im going to die and could not figure out what was wrong . I called my GI doctor he didn't Think its the med I went to my reg doc she said it is and cut my doze to half. I stopped taking it 2 days now because my pharmacy didn't have my new prescription ready I just came acrossall these rreviews and I will not even take a lower doze ill rather deal with my gastritis and Gerds. I ca F 35 5 weeks
40mg
7/26/2014

 1  Acid reflux Side effects included terrible muscle spasms and cramps in my leg, foot, and toes, trembling, sweating profusely, and I ended up in the ER today diagnosed with pleurisy! Can Protonix be causing all of this? I did NOT have any of these problems 9 days ago... F 51 9 days
40mg
7/15/2014

 2  Prevacid Quit working for Acid Refl Gas increased. Causing me to go to ER after one week. After checking that heart was okay. Took xrays showed excess gas in stomach and sigmoid colon. Doctor says its takes three weeks to help. Not sure about that. M 56 2 days
40 Mg
7/11/2014

 1  Acid Reflux Joint Pains At first I didn't put it together....but as soon as I started this drug I had severe joint pains. My left knee felt like I was a golden girl. Then it was my right leg that started hurting. I went to the doctor several times complaining about these problems. They just looked at me dumbfounded and suggested anxiety meds. Not one of them said....hey maybe it's a side effect of what your taking. Before Acid Reflux I never really took any medication regularly so I never thought about side effects before. And the sad part is, the Protonix didn't even help my Acid Refux problems and I had to go on a different medicine. And unfortunately I get joint pain on all PPIs. Please warn your friends about these drugs and suggest they not start them. F 35 6 weeks
20mg 2X D
7/8/2014

 3  Mild Gastritis Brain fog, feeling like a zombie, hand and ankle pain, left eye twitching and feeling like something in it, balance/motion sickness, fatigue, shoulder and back pain. It seems like I cannot obtain a deep, restorative sleep. It worked within a day or two to stop my pain from mild gastirits but after about a month the side effects caused me to stop cold turkey. Inability to keep a thought and impaired memory recall scared me off it. M 43 7 weeks
20 2X D
7/7/2014

 4  GERD/excess stomach acid None. I had a mostly great experience with Protonix. It helped me a lot for the better part of 10 years. Thing is, it just randomly stopped working for me about a month ago and since then it's been agony. I have been on just about every anti-reflux medication that exists so it's basically back to square one. F 32 8 years
40mg 2X D
6/24/2014
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 1  GERD Horrible! Put me in hospital! F 33 3 months
40
5/28/2014

 1  GERD, reflux, gallbladder removed After taking 40mg/day for a year started having following symptoms...strange dreams, severe numbness/burning pain of toes and balls of feet, tingling in fingers, cramping in abdominal area, fatigue. Also 40mg/day did not totally eliminate my reflux. After researching side effects, immediately took myself off meds. Went cold turkey. After 3 days, numbness/tingling in my feet and hands are lessening.Hope to be back to normal soon. Joints are not as achy (knees/lower back/shoulders) however still feeling somewhat fatigued. Started taking vitamins to try and turn around the fatigue and boost energy. Downside...Reflux is now absolutely terrible and can hardly eat anything...but will tough it out before trying another med. Using Tums and taking ginger, and mixed enzyme capsules to lessen symptoms. Only eat soup of light meal for dinner. Losing weight in a not good way. F 57 1.5 years
40mg 1X D
5/18/2014
Email
 1  Reflux Severe headache, jabs joint pain, preasure in head and anxiety. F 49 3 days
40mg
5/10/2014

 1  gerd, asthma Experiencing brain fog, fatigue, poor sleep, muscle spasmz and cramping and joint pain. Stopping immediately after reading about so many with similar side effects. F 47 3 weeks
40mg
5/8/2014

 1  GERD Very dry, very oddly flaky skin on my face led to a raw, angry, red facial rash. Foot and toe cramps. F 46 1 weeks
20
5/2/2014

 1  Stomach Ulcers (2) Pantoprazole 40mg: Anxiety, Severe Insomnia, Blood Pressure problems, drastic weight loss, THIS STUFF IS RUINING MY LIFE!!! If anyone else experienced this, please tell me how long it took to get it out of your system, and did the side affect subside?!? PLEASE HELP! I have been to the ER three times, been back to the GI specialist, primary care DR, no one seems to think the PPI's cause these problems, but I see many others on here with them! I have no health history at all, healthy as can be until i took the Pantoprazole. My health and my life have deteriorated so much in these 5 weeks. Any advise could save my sanity and my life... M 31 5 weeks
40 1X D
5/1/2014
Email
 2  Esophagitis Just took a pill last night. My legs and arms feel tingly and week. M 30 1 days
40mg
4/29/2014

 5  Acid reflux Was given in hospital for gallbladder life saver when compared to nexium F 28 2 years
40mg
4/21/2014

 1  To heal ulcer HORRIBLE drug! Ran out of sample Dexilant which had been causing NO problems and doc sent in script for Protonix even though I told him I had horrible side-effects from Prilosec. Protonix is worse than Prilosec: terrible tinnitis, swimming vision, awful headache and stiff neck, felt EXTREMELY ill, head felt like it was stuffed with cotton and I was in a different universe, heart palpitations, terrible sleep and muscle cramps. Never had a drug cause this many terrible side-effects after taking only two days. Unbelievable. STAY AWAY FROM THIS DRUG!!! M 62 2 days
40mg 1X D
4/18/2014
Email
 1  Esophegial ulcer and GERD Horrible and constant nausea, debilitating stomach pain, bowel pain and cramping, dizziness, diarrhea. The nausea was the worst part. I felt like i couldnt breath out of my mouth or i was gonna throw up. Symptoms resolved two days after stopping. F 26 1 months
40mg
4/14/2014
Email
 2  Acid reflux Terrible dizziness and increased neck pain. Tiredness and more bowel movements than usual. Stopping it. F 28 3 days
40mg 1xday
4/1/2014
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 5  Gastric ulcer- no. Other meds worke None This med saved my life! I have a horrific bleeding gastric ulcer from taking steroids for other medical conditions. This med has given me my life back! F 45 8 years
40mg 1X D
3/25/2014

 1  Possible GERD with asthma Extreme anxiety, unable to relax physically, palpitations and increased heart rate. Other PPIs may not have the same side effects or intensity od side effects. F 54 3 days
40 mg 1X D
3/16/2014
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 2  GERD Sore throat, headache, stiff neck, pain in back of neck, feeling of hair in throat, tingling burning legs at night, ear pain. I was prescribed Protonix after six weeks of Prilosec which was even worse. While Protonix was a slight improvement, it is still causing overwhelming side effects. Sore throat, pain in back of neck like a feeling of stiffness, pain at base of neck near lymph nodes, feeling of hair in throat, shooting headaches, problems with contrast in vision, legs feel hot at night. I'm weening myself off and never trying getting on another PPI again. M 45 10 days
20 MG 2X D
3/13/2014
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 1  Acidity Severe leg cramps- could not sleep all night F 31 8 days
40
3/12/2014

 1  acid reflux tiredness, dizziness, depression, stomach pain F 66 14 days
20mg 2X D
3/11/2014

 1  acid reflux Horrible leg pain that goes all the way to my neck and head just the left side . All this types of medicine gave me just more pain its not worth it . F 31 1 days
40
2/16/2014
Email
 1  GERD and non-ulcer dyspepsia Well, it helps GERD and indigestion. However, the likely tradeoffs have included vitamin deficiencies (B12 and D3), decreased bone density, aggravation of IBS, and (in combination with an antibiotic) c. difficile. I believe all PPIs should be banned. I've tried most of them over a 15-year period. Their pattern is that they help the GERD/dyspepsia for awhile, then start to cause IBS or to worsen it. And all the while, the even more sinister effects -- lowering of bone density, vitamin deficiency, possible predisposition to c. difficile by depleting all acid from stomach and thereby allowing "bad" bacteria to flourish -- are taking place. F 63 12 years
40 mg 1X D
1/24/2014
Email
 2  acid reflux Headaches, weakness, tired F 24 1 days
40 mg
12/23/2013

 1  acid reflux Ringing in the ears, belching, bad heartburn, chest pain, facial throbbing, occasional numbness in arms. A drug with such side effects should not be allowed on the market. Especially with doctors being ignorant of side effects, and all possible side effects not being listed on the prescription prospectus. How is a drug that can (and has) caused blindness and death be allowed on the market? F 58 6 months
20 mg 1X D
11/9/2013

 1  Bleeding Ulcer / Gastritis Severe Dizziness/Vertigo/Weakness/Left eye pain/Blurred Vision - ER once and hospitalized once. Back pain started 3 months after starting this drug. 9 months in, I had what they called occular migraines. Trace blood in my urine 7-9 times in 3 years. Started getting restless leg syndrome terribly and tingling in toes. I felt like this was coming from my brain down to my feet. Muscle aches, right hand swelling with trigger finger effect. My EKG showed that my heart skipped a beat now and then. I stopped taking this drug 2 months ago and am getting massages to help with the restless legs and started taking magnesium tablets. No more vertigo however still feel dizzy and extremely tired at times. Rare to have eye pain now and the blurriness is starting to clear up also. I have been to every doctor possible and none of them ever suggested that it might be a prescription I was taking. I read up on it myself and when I read all the comments on this site, it was like I related to everything people were saying about their experience. F 67 4 years
40 1X D
10/26/2013

 1  GERD Nausea, severe stomach cramps, severe headaches, muscle aches, vomiting and not able to eat at all. I stopped eating after 7:00 pm and decided I would rather deal with waking up hungry in the morning than laying in bed for days not being able to move or eat!!!! I don't care what my doctors says! I will never ever use PROTONIX ever again!!!!! F 38 11 days
2X D
8/11/2013
Email
 1   Tingling, numbness, tremors, joint pain, migraines, loss of clear vision, anxiety I attempted to stop using this drug, which caused my first migraine. Later, I began taking the drug again. As before, when I decided to stop taking it, I experienced a loss of vision, a migraine, and a hopsital visit. For me, the acid reflux is not as bad as the side effects from the druge. M 36 180 days
40 MG 1X D
7/5/2013
Email
 1  prevent ulcers from transplant meds burning moutn syndrome, terrible depression nausea I've spent 5 years suffering from the effects of this drug my doctors were too stupid to even think of it causing problems. I was down to eating rice and mashed potatoes. Horrible it should be taken off the market. Jitters and brain vibrations F 56 7 years
10 2X D
6/16/2013
Email
 1  gastritis Severe Depression, really really down and negative thinking of life Be-careful because I wouldn't never think of acid reflux tablets doing this! M 34 40 days
40 1X D
6/5/2013
Email
 2  Acid It killed my sex drive M 32 1 days
40
5/7/2013
Email
 1  acid reflux SEVERE depression - Suicide sounded good. I've never been depressed a day in my life before this. Nausea Ringing in my ears Chronic cough/mucus/ lead to infection in lungs Joint pain (could not eve hold a pen to write) Edema throughout my entire body Super sensitivity to the sun Not worth it. F 44 4 months
40mg 1X D
5/6/2013
Email
 3  Ulcer GERD Originally, Dizziness, Flatulence, Loose Stools, then Asthma like cough last 3 years. Took originally for an ulcer caused by ALIEVE, was tolerated well, only flatulance, loose stools, dizziness. Last couple of years, started having asthma like feeling., mucus in throat and lungs, causing severe and constant coughing. When I stopped taking Protonix, they stopped, but took 2 weeks to recover. Taking just 1 pill now causes it to flair up again. M 63 8 years
40 MG 1X D
4/1/2013

 1  Gastric Inflammation horrible back spasms, foot spasms, migraine, insomnia, irregular heartbeat. low magnesium symptoms didn't happen right away but when they did, it felt like getting hit by a train. F 35 2 weeks
40mg
3/25/2013

 1  GERD, gas, sensation of choking Loose stools 3x a day. Anxiety. Had nightmare on the 2nd day of use. Woke up and had heart beating fast. Feeling buzzed and jumpy like i just had coffee. Sudden leg muscle pain on my right leg. I felt better after i stopped. Gas and acidity came back but id rather take maalox than take this drug. Will ask dr to shift meds to a different kind. Asked to take for 2 weeks but cant do it. F 33 2 days
40mg
3/20/2013
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 1  Acid Reflux Severe depression Shortly after starting this medicine (after having taken omeprazole for a long time), I began thinking it was a good idea to drive my car off a bridge. It was a very detached sort of depression, but overwhelming. I stopped taking the Protonix, and these thoughts went away pretty quickly. No history of depression prior to that, or since. F 45 1 months
20 MG 1X D
12/31/2012

 5  Acid Reflux No side effects. Been taking daily for 10 years for chronic reflux. Great med. M 34 10 years
40 mg
12/27/2012

 4  GERD Everything was Great for Years, No GERD. I switched to Dexilent which is Even better but my insurance dropped it and it costs $2,000/ yr. I went back to protonix and Noticed Severe Muscular Pain and weakness and stiffness in ankle, Back and elbows and neck. I read that it Blocks Magnesium, So I started Taking Magnesium Pills and a Vitamin Pill Daily, and Pain a and Stiffness are Going Away LIKE A MIRACLE!!! M 43 10 years
40mg 1X D
12/11/2012
Email
 1  GERD Anxiety, gas pains, total loss of appetite F 21 2 weeks
40 MG 1xD
11/22/2012

 1  severe acid reflux pain in left eye and flashing dizziness after a week this medicine works for awhile,but has very dangerous side effects F 70 60 days
40mg 1X D
10/26/2012

 2  heartburn, acidreflux, nausea, pain I felt nauseous and had a loss of appetite, even worse than I experienced from my acid reflux. It helped slightly, but not as much as nexium did. After ten days I decided to switch back to nexium. Now my doctor thinks he was wrong all along and that I really have lazy gallbladder. If you ae experiencing these symptoms and your other tests are normal, ask about lazy gallbladder. F 15 10 days
20 mg 2x
10/4/2012

 5  Bleeding Gastric Ulcer Tired, Burping, Gas, Nausea I had very servere bleeding ulcers that kept me in ICU for nearly a month, I had 3 surgeries, and they placed me on protonix to reduce the acid in my stomach. This medicine is very helpful, it does its job and keeps my ulcers from happening again. F 17
40 mg 1X D
9/7/2012
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History
 1  Antral gastritis Myalgia. Nausea after eating. Severe stomach cramps. Burning mouth syndrome. Diarreah. Pp F 56 1 months
20
7/26/2012

 3  Gerd/Acid Reflux Disease Gas, muscle pains , headaches, loose stool and anxiety I think that protonix may be helping but the sideffects are bothersome M 36 48 days
40 2X D
6/20/2012
Email
 5  gerd None EXCELLENT DRUG! After years of trying everything known to man this was a God send! F 54 11 days
40mg 2X D
6/19/2012
Email
 2  Stomach Pain / Acid Reflux I started taking Protonix and instantly experienced a lot of different side effects the next day. Diarreah up to 4 times a day, numbness in my toes, very vivid nightmares, and severe headaches. I was having to take pepto bismol up to 3 times a day to counteract having to use the restroom. F 21 1 weeks
20
6/18/2012

 3  GERD, reflux, heart burn my god, after reading what some are saying I am stopping ASAP Now I know why my right eye is has been bothering me and no one can tell me what's going on with it. Body, muscle and joint pain coming out of nowhere, like fibro/MS sysmptoms. It has worked to stop the GERD and reflux - but I think it is killing me slowly in other ways. My hips have started hurting and my toes all give me pain first thing in the morning. Wlking is getting tougher. I will be slowly stopping this and monitoring my progress. Thank you all for your rating of this product, your comments may have saved my life or at least improved it! M 62 4 years
20 mg 1X D
5/9/2012

 2  GERD Leg cramps, ears ringing F 29 2 months
40 MG
5/7/2012

 1  Gastritis from H. Pylori Protonix a little bit of tingling, muscle spasms, bad muscle pains, anxiety, and depression. I've tried all PPI's and don't know what to do to cure the gastritis. M 28 3 weeks
40MG 1X D
4/17/2012
Email
 4  acid reflux low energy, jittery, stomach issues I've been on Protonix almost continuously for the past 8 years. I had started taking it on an as needed basis but then developed gastritis and went back on the daily dose. The last few months I've been having diarrhea after every meal. Dr suspected I was suffering from malabsorption based on symptoms. I went off all medications in preparation for a stool study and once I stopped the Protonix, things returned to normal. After a few days of heartburn I took Protonix for 2 days, and the stomach issues came back. Dr suggested I stop the Protonix fully and go with an OTC product for a while to see if we can identify Protonix as the root cause. Otherwise malabsorption and back to 14 pills of digestive enzymes a day. M 42 8 years
40 MG 1X D
4/13/2012

 3  acid reflux/chest pains due to acid headache radiating to neck. Tired. Took it for months at a time off and on and stopped when stomach bloating would begin to occurr every morning. went off of it for a few months and when started again due to nagging reflux chest pain the headaches were obviously triggered from the med after daily morning dose. Would last through evening and be gone by morning until i took next dose. I went back on protonix this time because of acid/chest pain that has been bothering me off an on daily (some days hardly at all though). I got off of Klonipin (benzo) and reflux pain became constant due to withdrawal. Tried protonix to see if it would help that symptoms - it did take the pain away, but the darn headache is bugging me everyday since i started taking it again. Had no headache this morning, took the Protonix, and now headache and neck is stiff. Also tired a while after taking it and get vision problems too - can't focus. Guess i will get off of them again and see if the reflux gets better the longer i am off the klonopin. F 45 1 years
40 mg 1X D
4/5/2012

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