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Drug Ratings for PROTONIX

Average Rating: 2.8 (278 Ratings)

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DISORDERS, ACID PEPTIC   

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)   

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    New! Reviews Summary for PROTONIX  | Top 10 Adverse Effects (reported to FDA)

RATING  REASONSIDE EFFECTS FOR PROTONIXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
sort down sort up F  M  
 5  Acid reflux Was given in hospital for gallbladder life saver when compared to nexium F 28 2 years
40mg
4/21/2014

 1  To heal ulcer HORRIBLE drug! Ran out of sample Dexilant which had been causing NO problems and doc sent in script for Protonix even though I told him I had horrible side-effects from Prilosec. Protonix is worse than Prilosec: terrible tinnitis, swimming vision, awful headache and stiff neck, felt EXTREMELY ill, head felt like it was stuffed with cotton and I was in a different universe, heart palpitations, terrible sleep and muscle cramps. Never had a drug cause this many terrible side-effects after taking only two days. Unbelievable. STAY AWAY FROM THIS DRUG!!! M 62 2 days
40mg 1X D
4/18/2014
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 1  Esophegial ulcer and GERD Horrible and constant nausea, debilitating stomach pain, bowel pain and cramping, dizziness, diarrhea. The nausea was the worst part. I felt like i couldnt breath out of my mouth or i was gonna throw up. Symptoms resolved two days after stopping. F 26 1 months
40mg
4/14/2014
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 2  Acid reflux Terrible dizziness and increased neck pain. Tiredness and more bowel movements than usual. Stopping it. F 28 3 days
40mg 1xday
4/1/2014
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 5  Gastric ulcer- no. Other meds worke None This med saved my life! I have a horrific bleeding gastric ulcer from taking steroids for other medical conditions. This med has given me my life back! F 45 8 years
40mg 1X D
3/25/2014

 1  Possible GERD with asthma Extreme anxiety, unable to relax physically, palpitations and increased heart rate. Other PPIs may not have the same side effects or intensity od side effects. F 54 3 days
40 mg 1X D
3/16/2014
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 2  GERD Sore throat, headache, stiff neck, pain in back of neck, feeling of hair in throat, tingling burning legs at night, ear pain. I was prescribed Protonix after six weeks of Prilosec which was even worse. While Protonix was a slight improvement, it is still causing overwhelming side effects. Sore throat, pain in back of neck like a feeling of stiffness, pain at base of neck near lymph nodes, feeling of hair in throat, shooting headaches, problems with contrast in vision, legs feel hot at night. I'm weening myself off and never trying getting on another PPI again. M 45 10 days
20 MG 2X D
3/13/2014
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 1  Acidity Severe leg cramps- could not sleep all night F 31 8 days
40
3/12/2014

 1  acid reflux tiredness, dizziness, depression, stomach pain F 66 14 days
20mg 2X D
3/11/2014

 1  acid reflux Horrible leg pain that goes all the way to my neck and head just the left side . All this types of medicine gave me just more pain its not worth it . F 31 1 days
40
2/16/2014
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 1  GERD and non-ulcer dyspepsia Well, it helps GERD and indigestion. However, the likely tradeoffs have included vitamin deficiencies (B12 and D3), decreased bone density, aggravation of IBS, and (in combination with an antibiotic) c. difficile. I believe all PPIs should be banned. I've tried most of them over a 15-year period. Their pattern is that they help the GERD/dyspepsia for awhile, then start to cause IBS or to worsen it. And all the while, the even more sinister effects -- lowering of bone density, vitamin deficiency, possible predisposition to c. difficile by depleting all acid from stomach and thereby allowing "bad" bacteria to flourish -- are taking place. F 63 12 years
40 mg 1X D
1/24/2014
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 2  acid reflux Headaches, weakness, tired F 24 1 days
40 mg
12/23/2013

 1  acid reflux Ringing in the ears, belching, bad heartburn, chest pain, facial throbbing, occasional numbness in arms. A drug with such side effects should not be allowed on the market. Especially with doctors being ignorant of side effects, and all possible side effects not being listed on the prescription prospectus. How is a drug that can (and has) caused blindness and death be allowed on the market? F 58 6 months
20 mg 1X D
11/9/2013

 1  Bleeding Ulcer / Gastritis Severe Dizziness/Vertigo/Weakness/Left eye pain/Blurred Vision - ER once and hospitalized once. Back pain started 3 months after starting this drug. 9 months in, I had what they called occular migraines. Trace blood in my urine 7-9 times in 3 years. Started getting restless leg syndrome terribly and tingling in toes. I felt like this was coming from my brain down to my feet. Muscle aches, right hand swelling with trigger finger effect. My EKG showed that my heart skipped a beat now and then. I stopped taking this drug 2 months ago and am getting massages to help with the restless legs and started taking magnesium tablets. No more vertigo however still feel dizzy and extremely tired at times. Rare to have eye pain now and the blurriness is starting to clear up also. I have been to every doctor possible and none of them ever suggested that it might be a prescription I was taking. I read up on it myself and when I read all the comments on this site, it was like I related to everything people were saying about their experience. F 67 4 years
40 1X D
10/26/2013

 1  GERD Nausea, severe stomach cramps, severe headaches, muscle aches, vomiting and not able to eat at all. I stopped eating after 7:00 pm and decided I would rather deal with waking up hungry in the morning than laying in bed for days not being able to move or eat!!!! I don't care what my doctors says! I will never ever use PROTONIX ever again!!!!! F 38 11 days
2X D
8/11/2013
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 1   Tingling, numbness, tremors, joint pain, migraines, loss of clear vision, anxiety I attempted to stop using this drug, which caused my first migraine. Later, I began taking the drug again. As before, when I decided to stop taking it, I experienced a loss of vision, a migraine, and a hopsital visit. For me, the acid reflux is not as bad as the side effects from the druge. M 36 180 days
40 MG 1X D
7/5/2013
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 1  prevent ulcers from transplant meds burning moutn syndrome, terrible depression nausea I've spent 5 years suffering from the effects of this drug my doctors were too stupid to even think of it causing problems. I was down to eating rice and mashed potatoes. Horrible it should be taken off the market. Jitters and brain vibrations F 56 7 years
10 2X D
6/16/2013
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 1  gastritis Severe Depression, really really down and negative thinking of life Be-careful because I wouldn't never think of acid reflux tablets doing this! M 34 40 days
40 1X D
6/5/2013
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 2  Acid It killed my sex drive M 32 1 days
40
5/7/2013
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 1  acid reflux SEVERE depression - Suicide sounded good. I've never been depressed a day in my life before this. Nausea Ringing in my ears Chronic cough/mucus/ lead to infection in lungs Joint pain (could not eve hold a pen to write) Edema throughout my entire body Super sensitivity to the sun Not worth it. F 44 4 months
40mg 1X D
5/6/2013
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 3  Ulcer GERD Originally, Dizziness, Flatulence, Loose Stools, then Asthma like cough last 3 years. Took originally for an ulcer caused by ALIEVE, was tolerated well, only flatulance, loose stools, dizziness. Last couple of years, started having asthma like feeling., mucus in throat and lungs, causing severe and constant coughing. When I stopped taking Protonix, they stopped, but took 2 weeks to recover. Taking just 1 pill now causes it to flair up again. M 63 8 years
40 MG 1X D
4/1/2013

 1  Gastric Inflammation horrible back spasms, foot spasms, migraine, insomnia, irregular heartbeat. low magnesium symptoms didn't happen right away but when they did, it felt like getting hit by a train. F 35 2 weeks
40mg
3/25/2013

 1  GERD, gas, sensation of choking Loose stools 3x a day. Anxiety. Had nightmare on the 2nd day of use. Woke up and had heart beating fast. Feeling buzzed and jumpy like i just had coffee. Sudden leg muscle pain on my right leg. I felt better after i stopped. Gas and acidity came back but id rather take maalox than take this drug. Will ask dr to shift meds to a different kind. Asked to take for 2 weeks but cant do it. F 33 2 days
40mg
3/20/2013
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 1  Acid Reflux Severe depression Shortly after starting this medicine (after having taken omeprazole for a long time), I began thinking it was a good idea to drive my car off a bridge. It was a very detached sort of depression, but overwhelming. I stopped taking the Protonix, and these thoughts went away pretty quickly. No history of depression prior to that, or since. F 45 1 months
20 MG 1X D
12/31/2012

 5  Acid Reflux No side effects. Been taking daily for 10 years for chronic reflux. Great med. M 34 10 years
40 mg
12/27/2012

 4  GERD Everything was Great for Years, No GERD. I switched to Dexilent which is Even better but my insurance dropped it and it costs $2,000/ yr. I went back to protonix and Noticed Severe Muscular Pain and weakness and stiffness in ankle, Back and elbows and neck. I read that it Blocks Magnesium, So I started Taking Magnesium Pills and a Vitamin Pill Daily, and Pain a and Stiffness are Going Away LIKE A MIRACLE!!! M 43 10 years
40mg 1X D
12/11/2012
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 1  GERD Anxiety, gas pains, total loss of appetite F 21 2 weeks
40 MG 1xD
11/22/2012

 1  severe acid reflux pain in left eye and flashing dizziness after a week this medicine works for awhile,but has very dangerous side effects F 70 60 days
40mg 1X D
10/26/2012

 2  heartburn, acidreflux, nausea, pain I felt nauseous and had a loss of appetite, even worse than I experienced from my acid reflux. It helped slightly, but not as much as nexium did. After ten days I decided to switch back to nexium. Now my doctor thinks he was wrong all along and that I really have lazy gallbladder. If you ae experiencing these symptoms and your other tests are normal, ask about lazy gallbladder. F 15 10 days
20 mg 2x
10/4/2012

 5  Bleeding Gastric Ulcer Tired, Burping, Gas, Nausea I had very servere bleeding ulcers that kept me in ICU for nearly a month, I had 3 surgeries, and they placed me on protonix to reduce the acid in my stomach. This medicine is very helpful, it does its job and keeps my ulcers from happening again. F 17
40 mg 1X D
9/7/2012
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History
 1  Antral gastritis Myalgia. Nausea after eating. Severe stomach cramps. Burning mouth syndrome. Diarreah. Pp F 56 1 months
20
7/26/2012

 3  Gerd/Acid Reflux Disease Gas, muscle pains , headaches, loose stool and anxiety I think that protonix may be helping but the sideffects are bothersome M 36 48 days
40 2X D
6/20/2012
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 5  gerd None EXCELLENT DRUG! After years of trying everything known to man this was a God send! F 54 11 days
40mg 2X D
6/19/2012
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 2  Stomach Pain / Acid Reflux I started taking Protonix and instantly experienced a lot of different side effects the next day. Diarreah up to 4 times a day, numbness in my toes, very vivid nightmares, and severe headaches. I was having to take pepto bismol up to 3 times a day to counteract having to use the restroom. F 21 1 weeks
20
6/18/2012

 3  GERD, reflux, heart burn my god, after reading what some are saying I am stopping ASAP Now I know why my right eye is has been bothering me and no one can tell me what's going on with it. Body, muscle and joint pain coming out of nowhere, like fibro/MS sysmptoms. It has worked to stop the GERD and reflux - but I think it is killing me slowly in other ways. My hips have started hurting and my toes all give me pain first thing in the morning. Wlking is getting tougher. I will be slowly stopping this and monitoring my progress. Thank you all for your rating of this product, your comments may have saved my life or at least improved it! M 62 4 years
20 mg 1X D
5/9/2012

 2  GERD Leg cramps, ears ringing F 29 2 months
40 MG
5/7/2012

 1  Gastritis from H. Pylori Protonix a little bit of tingling, muscle spasms, bad muscle pains, anxiety, and depression. I've tried all PPI's and don't know what to do to cure the gastritis. M 28 3 weeks
40MG 1X D
4/17/2012
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 4  acid reflux low energy, jittery, stomach issues I've been on Protonix almost continuously for the past 8 years. I had started taking it on an as needed basis but then developed gastritis and went back on the daily dose. The last few months I've been having diarrhea after every meal. Dr suspected I was suffering from malabsorption based on symptoms. I went off all medications in preparation for a stool study and once I stopped the Protonix, things returned to normal. After a few days of heartburn I took Protonix for 2 days, and the stomach issues came back. Dr suggested I stop the Protonix fully and go with an OTC product for a while to see if we can identify Protonix as the root cause. Otherwise malabsorption and back to 14 pills of digestive enzymes a day. M 42 8 years
40 MG 1X D
4/13/2012

 3  acid reflux/chest pains due to acid headache radiating to neck. Tired. Took it for months at a time off and on and stopped when stomach bloating would begin to occurr every morning. went off of it for a few months and when started again due to nagging reflux chest pain the headaches were obviously triggered from the med after daily morning dose. Would last through evening and be gone by morning until i took next dose. I went back on protonix this time because of acid/chest pain that has been bothering me off an on daily (some days hardly at all though). I got off of Klonipin (benzo) and reflux pain became constant due to withdrawal. Tried protonix to see if it would help that symptoms - it did take the pain away, but the darn headache is bugging me everyday since i started taking it again. Had no headache this morning, took the Protonix, and now headache and neck is stiff. Also tired a while after taking it and get vision problems too - can't focus. Guess i will get off of them again and see if the reflux gets better the longer i am off the klonopin. F 45 1 years
40 mg 1X D
4/5/2012

 1  Acid Reflux/GERD Belching, High Blood Pressure, Severe Headache, Back Pain, Tired and etc. I went to clinic due severe headache. It was sinus infection but I think Protonix got me good side effects. I will never take this again so I switch back to Nexium. F 44 4 weeks
40 MG 1X D
4/4/2012

 1  Acid Reflux/GERD It irritated my lungs and caused a slight burning sensation for about 9 hours after taking it. I tried it several times, but each time it caused burning in my lungs. I was able to tolerate Aciphex and Zegerid just fine, however. M 49 3 days
40 MG. 1X D
2/6/2012

 2  Acid Reflux/Gastritis I thought this drug was great because it kept my acid reflux at bay and I didn't have to worry about it, but now I just found out that I have several gastric polyps (30) and they most likely were caused by long term use of PPI's (proton pump inhibitors) like Protonix and Prilosec, which I was on before the Protonix. This is not good, so now I had to get off (slowly) but I am having to deal with the heartburn/acid reflux every day again now. I am very mad that none of my doctors that knew I was on this stuff for years didn't even warm me that this could happen with long term use. My advice is to stay off the stuff unless it's completely necessary, then only take it for a while, not several years. I am trying all the natural stuff I can find, (aloe vera, apple cider vinegar, baking soda, etc.) but so far, they don't work as well as the protonix did. F 50
40 mg 1X D
2/1/2012
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 1  Suspected Acid Reflux Took my first Protonix pill in the afternoon. At about 2:30 AM that night, I woke up with a fast heart rate very unusual for me. It was about 100 BPM vs normal at 56-60 BPM. This took a while to subside. I almost called an ambulance because this condition can be indicative of a blood stream drop in magnesium which can cause heart failure. Frequent urination and vivid dreams with shoulder pain persisted throughout the night. If you take this medicine and start getting fast, slow, or irregular heart rate, consider going to the emergency room if the symptoms do not stop in short order. There are other serious symptoms which are listed on the warning sheet. M 57 1 days
40 MG 1X D
1/27/2012

 5  acid refux I didn't think any until I read this article. Ringing in the ears, weight gain,anxiety, burning mouth, not sure what else. BUT I am concerned about vitamin B deficiency, osteo, and other side effects that aren't listed here. It works. While saying that I loved that drug, I changed my diet to fruit, raw and fresh veggies, chicken, turkey, fish. I am seeing a nutritionalist who designed a diet with recepies that will help me lose weight. After the first day I could tell a difference in my acid reflux. after a week I am going to talk to my doc because I want off this med. Several years ago, I did quit taking it and had to eat tums like crazy but I quit taking it. Yes AR was worse for a couple of days but I was determine. I am 58 years old and will do what I can to quit taking this drug and with the guidance from the nutrationalist. BTW-a small cup of Dairy Queen ice cream stopped AR in its tracks for me as well :) but I do not eat it anymore with my new reducing plan. Remember many times it is because of people being overweight that they have Acid Reflux. F 58 13 years
40MG 1X D
1/21/2012
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 5  Bleeding ulcer None M 29 3 months
1/6/2012

 3  GERD, ULCER, IBS Dizzy, off balance when walking, lightheaded, joint pain especially knee, feeling of sinus pressure, nausea, diarrhea I enjoyed not having the GERD issues. Had been on Prevacid (generic for 4 years). Take the Protonix with Bentyl and Carafate. Past two days the symptoms have occurred. Today I will take the Carafate and Bentyl and get back on the Prevacid to see what happens. I am too scared to take Protonix as is, but all the other comments here have me believing this is the right thing to do. Will call Dr. on Monday. Not liking the usage of all 3 as prescribed. F 42 18 days
40 2X D
11/26/2011
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 5  heartburn reflux Protonix has been a life saver for me. Nothing else worked. I have to take the name brand. Generic did NO good. My doctor always has to prior aurhuorize brand name for the insurance company. Heaven forbid you would have to take name brand in their eyes.it is the best medicine I've ever had for my stomach trouble. F 10 years
40mg
11/20/2011

 3  GERD Maybe Joint pain, muscle pain I have posted on 02/06/11 earlier. After more than 11years of using Protonix, I have finally had a better control of my GERD. I have stopped taking Protonix or any other prescription drug for almost three months without any intolerable acid reflux. I started drinking a lot of water, especially 30 minutes before each meal. I drink 8 oz of water every time before I eat. I have also elevated my bed, eat 5 meals a day with smaller portion, and stay away from food which causes acid reflux. But the major difference comes from drinking more water. After stopping taking Protonix, my joint pain/muscle pain also went away. M 57 11 years
1X D
11/18/2011
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 1  acid reflux headaches, nausea was terrible, light headed, very tired, and my blood pressure dropped. (The b/p dropping was a plus, but I don't like it sitting that low when I know it's not in my normal range.) I had orthostatic hypotension upon standing. I would not suggest anyone taking this drug unless you have no other options. I'd rather have the acid reflux and try to change my diet and deal. F 41 3 days
40 1X D
10/29/2011
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 4  Mild GERD and bleeding Bloating cause by slower digestion (because lowered stomach acid), slight regurgitation cause by slower digestion, softer stool. This med is effective at reducing acid in the stomach. But be aware that with lowered acid levels, your digestion will be a lot slower which means bloating and some regurgitation after meals. I started taking it after stomach pain and black stool. I took it for almost 2 months but decided to make diet changes instead. It turns out it was soda that's causing my stomach problems (I drink about 2 to 3 cans a day). I stop drinking Coke and slowly go off Protonix in 1 month period and it works out fine for me. Now there's no stomach pain. NOTE: MAKE SURE YOU GO OFF SLOWLY. With the lowered stomach acid level for a whole month, your body produce a large amount of chemical signals telling you stomach to produce acid. If you go off it suddenly, you will get extreme amount of acid in your stomach! You need to introduce acid back into your stomach slowly so you body stop producing those chemical signals. What I did was 1 day Protonix, next day take 2 150mg-Zantac; after a week of this, I take 1 day Protonix, then 2 days of 2 150mg-Zantac; another week, I take just 2 Zantacs no Protonix, then 1 Zantacs a day, then I stopped completely. Your schedule might vary; talk to your doctor. On hindsight, I should have done a lower dosage Protonix 20mg instead of Zantac since I have no side effects with it. If stomach pain comes back then maybe is something else in your diet that needs to change (think about what ever that's unhealthy or listed as possible causes), but in the me M 31 2 months
40mg 1X D
10/14/2011
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 1  GERD Anxiety, depression, fatigue, jitteriness Was prescribed protonix to treat GERD. Started taking it shortly after taking Pepcid AC. Noticed these side effects only about 1 week after taking Protonix. M 30 2 weeks
40mg 2X D
10/9/2011
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 2  acid reflux sinus pressure and headaches, dizziness, ringing in the ears, stomach cramping, I could initially tell a difference with reflux in taking protonix, but started having headaches and pressure on left side and ringing in the ears, which I presummed was due to sinus infection. Also had to really watch my diet and felt like acid reflux worsened over time. Stopped taking protonix because I really don't like taking any medications and did not feel like acid reflux was worse than the side effects. Having been on no other medications, I know it was from protonix. Started taking magnesium supplement and all symptoms, including acid reflux stopped. I would recommend researching how magnesium plays a role in bodily functions, especially how it reduces acid in your stomach naturally. Now I only take a magnesium supplement and have complete relief. F 34 2 months
40 mg 1X D
9/30/2011

 5  Severe acid reflux/ GERD None I love this stuff. I am a lap band patient and have severe acid reflux. It was so bad that my band would swell tight. This medicine is saving me. I have no reflux anymore. I can lay down at night and not feel like I have acid in my throat and my band doesn't swell anymore. F 43 1 months
40mg 1X D
9/28/2011

 4  ulcer, GRED occasional dizziness (like having too many drinks), ringing in the ears, flatulence I started taking this after having an ulcer caused by Aleve. I take it when needed now for acid reflux. I can take this easily. The generic version causes severe diarrhea. M 61 8 years
40mg 1X D
9/17/2011
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 1  gerd fatigue, severe stomach pain, extremely low blood pressure, confusion, headache, weakness I advise everyone to not PPI's anymore because it causes dependence, once you stop taking it you feel more acidity than every before. When i started taking this i ha rdly had any reflux problem, but after taking it continuously for months my symptoms worsened. I experienced more side effects than its benefits. Now when i try to stop this medication i feel acid rebound, and i am now stuck up with this.....feel like crying .....this has become a multi billion dollar industry and doctors and pharma companies are playing with the lives of the people...i..i earnestly plead everyone to start spreading worldwide awareness about the side effects of these PPI's .....and we should try to stop this ever flourishing industry....i wish i had never consulted a gastroentrologist for such a minor problem..... M 24 6 months
40 mg 1X D
9/1/2011
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 2  Acid Reflux severe stomach pains, fatigue Altho at first it seemed the protonix helped, 2yrs later really had to watch more what was eating - absolutely nothing with tomato sauce or spices. One night the pain was so severe went to ER (again) and this time they did a CT "with" contrast and low & behold a huge gallstone - immediate/emergency gallbladder removed and ER surgeon told my husband it was the worst one he'd ever seen (not largest but grossest). My recommendation if you're having GERD and it gets worse on protonix, have your gallbladder checked and removed. That was 1.5yrs ago and have not had acid reflux since and can eat again. F 50 2 years
40mg 2X D
8/29/2011

 2  GERD DIARRHEA, FATIGUE SO FAR THE SIDE EFFECTS ARE MORE UNCOMFORTABLE THAN MY GERD. INSURANCE DOES NOT PAY FOR TWICE A DAY. WILL TRY TO GAVE THE DOCTOR GIVE ME SOMETHING ELSE M 46 4 days
40 2X D
7/30/2011
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 2  Occasional Heartburn I have been on every PPI and this is the best one. I have weened from 80 mg to 60 to 40 to 20, soon I will go to 10. I eat a strict diet and take many enzymes and DGL with every meal. The belching and discomfort and burning (most likely gastritis, caused by the PPIs as it started after I took the drugs) have 90 percent gone. I am dreaming for the first time in two years since I started this med. Every time you go down in dosage you get rebound. 20 to 10 mg is essential as I tried cold turkey and after 4 days you are hurting badly. Let your gastrin levels slowly go back to normal. The funny thing is, I only had heartburn in the first place because I would eat pizza late at night after singing in bars and such with cigarette smoke, around alcohol, etc. On top of a horrible diet I was asking for it. The doctors who prescribe this sure do get their bonus, but I wonder if it's worth the price of their souls haha. Most of us don't even need this, we just need a wake up call. If we stopped e I gave it a two only because it stopped the reflux. This is NOT A CURE. It makes you completely dependent. Cyclical profit needs cyclical demand, and cyclical demand in the pharmaceutical world means cyclical sickness. What major cures have their been since Polio? There is too much money in sickness. Google how much the reflux business is worth every year....it's no conspiracy, it's just business. M 23 2 years
80mg 1X D
5/3/2011
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 1  GERD I lost 3 pants sizes and became extremely ill with a swollen liver and gallbladder before I knew what was causing the reaction. I had blood work that came back normal, but for a month I thought I was dying because I was sick every time I ate. Finally tapered off, but still left with symptoms of chronic fatigue now. F 50 1 years
30 mg 1X D
4/7/2011
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 5  Acid reflux None I'm surprised so many people had side effects from this drug as I experienced complete relief from acid trouble with no side effects. However I don't trust these drugs are safe long term, so I only take it when I have major flare ups and it works well. M 28 1 months
40 mg 1X D
3/31/2011
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