PAXIL CR Reviews (PAROXETINE HYDROCHLORIDE)

Average Rating: 3.3 (595 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PAXIL CR  (PAROXETINE HYDROCHLORIDE):  Paroxetine is used to treat depression, panic attacks, anxiety disorders, and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. Paroxetine is known as a selective serotonin reuptake inhibitor (SSRI). This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. Paroxetine may lessen premenstrual symptoms such as irritability, increased appetite, and depression.   FDA Approval Date: 2000-12-06 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PAXIL CR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PAXIL CRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Anxiety and panic disorder Fatigue only. I am myself now with help of this medication. F 53 21 years
25 mg 1X day
3/25/2021
 5  anxiety caused by menopause Some weight gain, tiredness in the beginning Complete life saver. Take it at night and it works best. I stayed at lowest dose and let my body get used to it. It did not take the full 6 weeks to work for me--saw great results sooner. I have zero anxiety now. F 55 1.5 years
12.5 1X day
5/1/2016
 5  OCD On and off this drug for 8 years, in that I went off of it once for a few months. I'd been on for a good few years before going off and had zero withdrawal or problems going off it by tapering down. For now, I need Paxil and Seroquel to have a decent quality of life, as off the drug, my anxiety rules my mind with obsessive horrible thoughts that plague me. The only side effects I have are slightly delayed orgasm and mild constipation. Paxil CR is well tolerated by me and as you can see, I've been on it uninterrupted for about 6 years. When I went off of it briefly, my OCD came back hard...so back on it. M 40 8 years
32.5mg 1X day
4/9/2016
 5  Depression Stomach and constipation problems. Worked very well for me. F 60 4 years
5mg. 1X day
9/17/2015
 5  over 10 years on and off Only medication that works for my anxiety. With all the medications on the market this is the best one. I have tried pretty much every SSRI,SNRI, Lamictal etc. Paxil works the best and I always go back too it. I can completely go off it cold turkey without any withdrawal symptoms. As far as side effects go the only drawback for me is fatigue. It is a powerful drug and at my current dose it does make me tired so I take it at night. Also if your not careful with your diet it will lead to weight gain. M 39 10 years
37.5 2x da
9/17/2014
 5  panic disorder Okay, I didn't take much, and I had a bad allergic reaction to it (BAD, as in, couldn't breathe, hives around throat) ...but I swear this stuff is like COCAINE or something. I've got Graves and really shouldn't be on anti-depressants (am not a depressed person, etc), but doc wanted me to try it at 20mg/day. I took 5mg knowing it might hurt me (though I didn't know about the allergy; one zoloft just made my hr go up to 200bpm and ER). I never knew "happiness" before that one dose, SO MUCH that even with the hives, I took another few days of 5mg, then 2.5mg, then 2.5mg (then pharmacist had us flush them). #ADDICTIVE There were "bad" side effects even on low dose, and I took it 4 days only, but this kept me happy like "high" for a full week even after I stopped. I can't take zoloft or most SSRIs, and Paxil was a last-ditch on my doctor's part. I was allergic. AND STILL WANTED TO TAKE THEM. That should tell you something. Of course, I'm not "depressed"; I slept well the first night (couldn't breathe well, needed lots of benedryls the next few nights), but felt like I COULD FLY I was so happy inside. This is definitely "the one that got away". I think they'll give us Paxil in Heaven and we won't have allergic reactions! —Daddy was/is on it for decades for depression; he is so calm/cool/relaxed all the time that people COMMENT, so I was more than happy to try this! I can't believe I had such a bad allergic reaction to it :( But yes, if you can take it, DO SO. I was scared by the tales of getting off Paxil, but if you take it, I don't much think you'll care about getting off it one day, lol. F 35 4 days
5 1X day
4/19/2014
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 5  PTSD,ADD,ANXIETY,DEPRESSION, Constipation. Increased appetite, weight gain. I noticed within one month of taking Paxil CR, the ability to stop my mind from racing occurred and I was able to fall asleep. Prior to Paxil CR, I couldn't stop my brain from racing and it caused sleepless nights as a result. I have feelings of euphoria, and I am less emotional. That's a good thing because feeling depressed and sad all the time can make one ill and cause hospitalization. Needless to say, I would recommend this medication. I took Zoloft for year's, but it made me aggressive and caused uncontrollable muscle movement. Paxil CR by far is a much better antidepressant. F 57 3 months
25 MG 1X day
4/10/2014
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 5  Horrible anxiety and depression weight gain and carb cravings. very tired and anorgasmic when on 25 mgs. but not when on 12.5 mgs. Paxil has saved my life several times over past 12 years. I have been on and off of it depending on stressful situations in my life. It does cause major weight gain but it is the only med that helps me with major anxiety. Helps a lot with IBS also. A great drug for me!! F 50 12 years
12.5/25 mg 1X day
7/29/2013
 5  Depression/Anxiety/Panic Disorder Why are any of you taking regular Paxil? The drug has been reformulated as Paxil CR (constant release). The new formulation takes away most if not all of the side effects as the problem with regular Paxil was its short half-life (4 hours). Doctors should NOT be prescribing regular Paxil anymore. Paxil CR is an entirely different drug. Only use BRAND NAMES when it comes to AD's as the generics just don't cut it. Paxil CR 12.5 MG knocked out my depression and severe anxiety/PD within days. It's a good drug. If you need to withdraw from any SSRI use Lyrica. It's like a beta blocker for the brain and will cancel out any and all withdrawal symptoms from any SSRI/SNRI. For weight gain, sexual dysfunction associated with this or any SSRI take the herb Rhodiola Rosea. It's a miracle herb. M 39 2 years
12.5
6/30/2012
 5  OCD/Panic Disorder WEIGHT GAIN!!!! Gained 20 pounds easily within 2 years. Don't let anyone tell you it's not the Paxil CR. I was a competitive runner and STILL gained weight. I went on a 1,200 calorie diet for over a month and exercised 6x a week. I wrote down everything I ate and DIDN'T LOSE ONE POUND! Stopped taking Paxil CR and lost 2 pounds in one week while eating anything I wanted. With that said, Paxil CR eliminated my OCD symptoms. It was wonderful in that regards but I ended up feeling depressed when month after month I kept on gaining weight. I stopped taking it for that reason alone. I am now on Villbryd and trying to see if I can lose this weight. F 46 2 years
37.5 1X day
6/11/2012
Email
 5  Anxiety (GAD, Panic, OCD) Slight weight gain. Dry mouth. Entertaining dreams. Emotional numbness. Was basically non functional for 6 months because of anxiety and lost 30 pounds. Tried Lexapro and gave it 5 weeks. Only gave me headaches. Also tried Xanax and Clonopin and while they worked, I would very quickly get rebound anxiety which put me into a spiral of hell. Finally found Paxil CR and it returned me to normal in 48 hours. Probably had the best year of my life on this drug even with intense times of stress. Oh, and it almost completely cured my IBS. It does cause emotional blunting. You still feel the emotion, you just don't yell or cry. Tried tapering off and IBS came back. Back on it again and back to normal. M 40 1 years
12.5 1X day
3/8/2012
 5  depression, anxiety, hopelessness, Paxil was a life-saver back in December 1996. I was depressed, anxious, scared, lack of self-conference, driving my kids crazy, needy, going through menopause, rocky relationship, felt zero joy with living, felt like a loser, etc. etc.....within 48 hours of taking Paxil I was beginning to say to myself "this must be what it is like to be normal". My kids saw the change within 24 hours. I have tried going off Paxil but immediately feel myself falling back down that black hole. My question is: "Can I be on Paxil for the rest of my life? I am now almost 72 years old but doing ok. F 71 15 years
20 mg 1X day
1/25/2012
Email
 5  Depression F 63 15 years
5MG 1X day
7/5/2011
Email
 5  Severe anxiety, insomnia, white noise, occasional headaches-but not sure if it's related to taking this medicine, Before I started taking this medication, I didn't know what was wrong with me. For about 6 months I couldn't sleep more than 4 hours per night, wasn't eating, food didn't taste or smell good. I constantly felt severe anxiety and tried so many things to feel better but nothing helped. My Dr. suggested I try Paxil and it took about 4 weeks for this medication to start helping me, but now I feel so much better. I really feel like it gave me my life back. I am loving my life again! F 42 6 weeks
37.5 mg. 1X day
12/27/2010
 5  Anxiety No sex drive, inability to orgasm, emotionless, inability to concentrate Somtimes i think this drug works too well. As in I don't care about much. I went back and forth from 12.5 to 25 mg. Withdrawls are REALLY hard. Ive tried to get off of the drug and just can't. No weight gain, maybe even decreased appetite. Great at combating anxiety, but it really just masks symptoms. F 26 6 years
12.5 1X day
6/4/2010
 5  Social Anxiety/Panic Attacks initially--loss of libido, unable to orgasm, vivid dreams, extreme sleepiness now--sexual side effects have decreased. still sleep more than before, but not as much as in the beginning. Weight gain has been the main problem--accrue around 10 lbs a year. Really creeps up if you are not watching. very effective at treating my social anxiety and panic attacks. 31 6 years
25 mg gene 1X day
5/27/2010
 5  anxiety disorder/OCD loss of sex drive, dry mouth I have suffered from Generalized Anxiety Disorder and OCD since childhood, and have found Paxil CR to be the best treatment for me. Like most people, I had to try several SSRI medications to find the "right" one for me. Paxil CR effectively controls all anxiety and OCD symptoms for me. The only side effects I experience are a decrease in sex drive & dry mouth. F 32 10 years
9/27/2009
 5  anxiety very few, slight weight gain,delayed ejaculation :) ocassional tiredness ... it works ! was on zoloft which landed me in jail made me freak'n psycotic unable to back down from any confrontation actually hit someone for first time in my life ! but Paxil works great relaxed and happy , but not numb .. FEEL NORMAL ! M 45 6 months
5/28/2009
Email
 5  Panic, Anxiety, Depression Insomnia Weight gain, some lethargy after having recovered It saved my life. At one point I was switched to the generic and I had a hard time adjusting to it. Was switched back to name brand. F 32 2 years
2/1/2009
 5  Anxiety and alcoholism A little weird at first, but after a week, nothing. I feel a strange euphoria. I don't actuallyb remember feeling this happy. I find myself smiling for no reason. It's wonderful. I don't know if it's a symptom or not, but I like it. I have not stopped drinking in the evenings. M 38 12 days
12/20/2008
  

PAXIL CR  (PAROXETINE HYDROCHLORIDE):  Paroxetine is used to treat depression, panic attacks, anxiety disorders, and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. Paroxetine is known as a selective serotonin reuptake inhibitor (SSRI). This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. Paroxetine may lessen premenstrual symptoms such as irritability, increased appetite, and depression.   FDA Approval Date: 2000-12-06 (Sources: U.S. Centers for Medicare Services, FDA)

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