PLAVIX Reviews (CLOPIDOGREL BISULFATE)

Average Rating: 2.2 (612 Ratings)

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 ANTIPLATELET AGENTS

 Type: Rx Drug

  

PLAVIX  (CLOPIDOGREL BISULFATE):  Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood circulation disease (peripheral vascular disease). It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open and prevent blood clots after certain procedures (such as cardiac stent). Clopidogrel works by blocking platelets from sticking together and prevents them from forming harmful clots. It is an antiplatelet drug. It helps keep blood flowing smoothly in your body.   FDA Approval Date: 2007-09-20 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age oldest to youngest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PLAVIXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  2 unmedicated stents At age 96 I had chest discomfort with shortness of breath after receiving 2 stents. The doctor put me on Plavix 75mg with 1 adult aspirin daily. For 6 weeks I suffered with nausea, vomiting, listlessness, nightmares, no social interaction due to depression, lethargy, no desire to get out of bed, persistent cough and fluid retention. Due to my age it was taken for granted that I was "just old", "had the flu", had "congestive heart failure". I ended up in the hospital with pulmonary edema after 2 weeks of taking Plavix. In the ER I did not receive Plavix for 24 hours. I started to feel better. The edema disappeared with IV Lasix. Once home I started on Plavix again and all the symptoms reappeared. For 4 weeks I lost weight, threw up, could not stand the smell of food and had extremely vivid nightmares. I was exhausted. I suspected Plavix caused all these side effects. Off Plavix now for 3 days and I have no signs of these side effects. I am still weak but eat well and have no stomach discomfort. The cough is gone. Now I am on 1 adult aspirin daily. My cardiologist is not happy, but I am happy. He said he has never had any patients with all these side effects. He was adamant that I should continue taking Plavix, but I will take my chances. Better off alive on a single aspirin a day than M 96 6 weeks
5/25/2008
 1  My uncle was put on Plavix My Uncle was taken off enteric aspirin and put on Plavix, for an unknown reason. He is 95 years old and in fair to good health (but a CT Scan shows an aneurysm in the aorta in his stomach), within in days of taking Plavix he has suffered a stroke and is now in a nursing home. Up to this time he lived by himself in his own home with family members checking and caring for him daily. It is my concern that Plavix should only be taken after a heart attack, stroke or a stent put in. And according to the Federal Gov't the makers are not open to the public. M 95 5 days
12/22/2006
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 1  Stents After 3 wks.swollen legs all fingers,swollen buttocks causing pain , bloated,no appetite easy bruising ,legs burning at night,hard to walk a straight line This is my only drug and it's a killer, not worth living under these conditions M 93 11 months
75mg 1X day
10/4/2022
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 2  ? irregular heart beat? maybe dizziness, especially in morning, had to close my eyes tightly to alleviate symptoms somewhat, afraid I would fall Feel so much better without plavix, can be active from the time I get up to late in the day. It may be raising my blood pressure 10 pts or so since I quit taking it. F 88 12 months
75 mg 1X day
7/4/2010
 1  Coronary protection after MI Confusion, instability, cough, loss of appetite, drowsiness I am an Anesthesiologist for about 14yrs now. My wife and I are also taking care of her great aunt who is now 88 yrs. old. My wife’s aunt had a minor heart attack in the end of December 2010. After which a cardiologist had placed her on Plavix. She had lived by herself and was very independent. Although she cannot drive, she could function independently and had no problems with taking care of herself. We had her stayed in a nursing home for cardiac rehab and later moved her to an assisted living facility after that. We had noticed that she started to develop a cough while in the nursing home. She was placed on antibiotic by her primary physician but it did not seem to subside. What was more concerning was her level of sedation and confusion. She was screaming help every night to the point of disturbing other residents from getting any rest. Her appetite does not seem to be there as well. There was concern that we would have to put her back into a nursing home which was truly not in her best interest given that was coherent about two months ago. We had thought hard about the possibility of Plavix as being the culprit and the risk of removing a medication that may prevent future heart attack. We had decided to have her taken off of Plavix on grounds of mental confusion and ultimately lack of quality of life. She is now off of Plavix for about 5 days and her confusion has dramatically improved and her cough went away. She is not back 100% yet but I hope th F 88 2 months
1X day
2/28/2011
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 1  stents GI Bleeding. Four Units of blood were given with transfusion. Huge bruises on the arms, Mental Confusion. Near Kidney Failure This is a very dangerous drug. My mother has been put on this, and the side effects put her life at excessive risk. F 88 365 days
1X day
7/18/2011
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 1  stent to diagonal within an hour or so of taking the loading dose (four tabs) before stenting I had a fainting fit almost passed out felt terrible. Since then have had series of similar attacks with hot flushes and panic attack symptoms. These have become more and more frequent - now every three or four days - very debilitating. I am on these for 12 months - can't wait to stop to see if all this goes away !! M 87 9 months
75mg 1X day
3/8/2017
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 4  TIA and aortic stenosis none. doctors wanted to do an epidural lumbar procedure to numb the pain i have in my rt knee. both my PCP and orthopedic told me to stop Plavix the week before the epidural. 4 days after stopping Plavix, i was brought to the ED with a TIA. doctors in the ED said do not stop taking Plavix and put me back on it. i am sufficiently upset by this............. F 86 14 months
6/14/2006
 2  heart attack with stint implant Difficulty stopping bleeding even from minor cuts. Sever bruising. After 2.5 years on it, developed rectal bleeding that required hospitalization and platelet transfussions to stop the bleeding. Now I'm off all blood thinners. It is a balance between having a heart attack or bleeding to death! M 85 2.5 years
2/3/2005
 1  TIA ON RIGHT SIDE OF BRAIN Multiple UTI'S, antibiotics did not work while on plavix. Than R Kidney infection. Mass amounts of urine beyond belief. In hosp taken off all meds so antibiotics worked than. But nurse said when ma goes home. Do not give her plavix tonite, we gave it to her this morning. So ma went to bed with no plavix, an next morning no bed full of urine. Durning the day, we went shopping with no piss coming threw her diaper an wheel chair. It was a blessing. Next nite gave ma 75mg plavix. Ma woke up pissed drenched. Pee'd her clothes as usual. We knew it was the plavix. Next nite we tried a 325mg aspirin. Ma pee'd like crazy as well. So we than cut plavix. in half. The peeing has stopped. But Ma use to walk with walker, an is now like rag doll, an I feel plavix is making Ma's legs not work. Her hearing goes on plavix, she gets with drawn. But I'm scared to take her off. But I'm scared to leave her on. Primary Care is affraid to make dicession. Says we have to find Doctor who put her on plavix from hosp when Ma had stroke. They got tons of Doctors putting ppl on this, but not notified of major problems, an side effects of this drug. Ma's dose was way to high. Blood thinners pull water out of person.. They need qualified stroke Doctors. Goggle has been more helpful than any Dr. Ma will ser neurologist monday. F 85 10 months
75mg
1/3/2015
 1  Cypher Sirolimus-eluting Stent Depression,nausea on continuing basis, "all over" shakey feeling, insomnia, vivid dreams when able to sleep, no social interaction because of feeling so bad My Dad at 85 years, had two stents implanted in Jan.'08. Cardiologist told him not to miss a day of Plavix for one year. I'm sure he would not have lasted one year his side effects were so bad. He continually said it was the Plavix.I contacted Bristol Meyers Squibb & they faxed me the information on the drug including tests conducted. The bottom line is the Plavix is no more effective than 325mg of Aspirin, so tell me why some doctors don't convey this to patients. I would like someone to explain to me why this drug was ever approved by the FDA. I hope this helps someone or their parent in the same situation! M 85 3 months
4/9/2008
 2  tia had dental xray before tia. gums and teeth ok. then found out serious gum infection yesterday and toothdecay afer 3 months on plavix. M 84 3 months
75mg 1X day
12/6/2017
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 1  stroke, summer of 2004 excessive bleeding that would not stop from minor skin cuts and scrapes; internal bleeding on arms and hands and legs from minor bumps; bleeding from gums - so dental work had to be delayed; developed internal bleeding from liver possibly from a fall; blood pressure dropped, went into shock, was saved by blood transfusions; however eventually died. Summary of side effects was submitted by relatives taking care of her. The relatives are aware of a family friend taking plavix who lost 2 quarts of blood on operating table during hip replacement because of inability to stop bleeding. The relatives also know of another elderly member of the extended family who had bleeding while on plavix and who stopped taking plavix. She lived awhile longer and then eventually succumbed to other ailments. How large, definitive, and unbiased is the body of studies indicating that the side effects of plavix are benign? What studies have been conducted to define a dosages of plavix that are tailored to the patient and safe for that patient? What studies have been completed of the impact of plavix on internal bleeding in the elderly who have a tendency to fall more often than younger people? What monitoring of plavix and its effects are being done by family doctors, specialists and hospital staffs to determine fully the short-term and long-term risks and benefits? What are family doctors, specialists and hospitals told about balancing the dosage of plavix with the side effects that may be coing on? How beneficial is this drug and how unsafe is it? Who has the answers? Signed by her dear friend, Cookie. F 84 1 years
7/25/2005
 1  Carotid endarterectomy Mother felt weak, fatigued, developed anemia, generally unwell, small blood cells. Energy improved as soon as this terrible medication was stopped. F 84 2 months
75mg 1X day
7/31/2020
 4  stent bruising, fatigue Its only been a little over 3 weeks, but my arms are so bruised they would scare children and old people! I am experiencing some fatigue especially in the a.m. However, thankfully I feel pretty good otherwise and I attribute that to the fact I am continuing to exercise one hr. per day 5 days a week with weights, stretches and walking/jogging which I have been doing for the past 41 years. Also, with my wife's cooperation I am on DASH diet. The blender drinks she makes help a lot! I called my cardiologist and complained about the bruising and fatigue and she practically pleaded with me not to stop the Plavix, saying it would be only for one year. I intend to go off it by stages at that point and let the DASH diet do the rest. Mostly though I'm thanking God for an already long life. M 83 29 days
75 1X day
6/9/2016
 3  To thin blood after stent implant bruising, excessive bleeding from small cuts. Cannot trace any other problems to PLAVIX. March 2007 had a stent implanted after experiencing heart pain. A week later a study showed stents are no better than medication. It was publicized on the national news. But now must take a blood thinner to prevent the plaque to build up on the stent. Kind of counterproductive, but too late for me. Plavix is expensive, and the company making it sued the generic equivalent and won. It is all about money. I now take a PLAVIX only every third day. When I run out of pills I may go to Aspirin 81. The Adult Aspirin maybe too strong. But everybody is different. M 83 20 months
12/9/2008
 2  Had drug-coated stent put in 10/04 After being on Plavix for 5 months, began having severe insomnia, tremor in hands and slurred speech. Speech has gotten progressively worse over last three months. Doctors have no answers, say it could be Parkinson's which could be triggered by medication. Wondering if Plavix could be causing this problem and if anyone else on Plavix has had this experience? Not sure if Plavix is helping or doing more harm than good F 83 8 months
6/21/2005
 2  open heart surgery & stents Severe dizziness and headaches. My doctor intended to prescribe Plavix for a year. At this site I noticed that some similar patients only took it for six months. I complained to my doctor and he agreed I could stop. In only 4 days I have recovered and am feeling very well. I actually went outside and did some gardening. F 83 6 months
1X day
5/21/2012
 1  Stent Had blockage and a stent was put in. I was put on Plavix after that. I have been on it for 9 months and have been in the hospital five times for severe bleeding and had a stroke six weeks ago. I continue to have loss of memory and getting worse everyday. Stay tired all the time as well. Going off Plavix today. M 83 9 months
10/29/2009
 2  2 Stents Fatigue,inability to concentrate, speech patterns interrupted, sleep irregularities,"RLS-type" symptoms all over body, major hair loss, skin problems, heart palps, mood swings, sinus infections, prolonged bleeding. Have been using as required by cardiologist with baby asprin. Have made complaints about the bloody noses and the laundry list of other side effects. Stopped the baby asprin and that seems to have helped with the bleeding. Per DR, I will be able to discontinue in about 2 months. F 82 1 years
3/29/2008
  

PLAVIX  (CLOPIDOGREL BISULFATE):  Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood circulation disease (peripheral vascular disease). It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open and prevent blood clots after certain procedures (such as cardiac stent). Clopidogrel works by blocking platelets from sticking together and prevents them from forming harmful clots. It is an antiplatelet drug. It helps keep blood flowing smoothly in your body.   FDA Approval Date: 2007-09-20 (Sources: U.S. Centers for Medicare Services, FDA)

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