ZOFRAN ODT Reviews (ONDANSETRON)

Average Rating: 3.7 (74 Ratings)

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 GASTROINTESTINAL, MISCELLANEOUS

 Type: Rx Drug

  

ZOFRAN ODT  (ONDANSETRON):  This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. Ondansetron works by blocking one of the body's natural substances (serotonin) that causes vomiting.   FDA Approval Date: 1999-01-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on ZOFRAN ODT: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ZOFRAN ODTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Hep c tx viekira makes me nauseous Severe HA one hour after first dose then jaw pain and feeling of anxiety and red face. My B/P which is usually 110/74 at most was 164/102 pulse 112 hard to breath. I was scared to death. Haven't taken much medicine in my life (my Hep C came from blood transfusion ) But would never take this one again!!! F 58 1 days
4mg
10/16/2015
Email
 1  nausea severe constipation I would only take this as a last resort. I'd rather take Phenergan or dramamine and be asleep than to be severely constipated. This is TMI (sorry), but after taking this for 2 to 3 days, I was severely constipated for a week or more with a giant ball of stool that could not be passed, consisting of many marble-sized balls of stool. Trust me, you don't want to go through what I went through. I have dealt with constipation from pain meds, surgery, etc., and nothing remotely compares to this extreme constipation. F 52 2 days
4 mg 2X day
6/16/2015
 1  doctor give me in hospital stomach Felt back of head burning so bad and couldn't pick arms up, with intense bone pain. Still have bone pain and headache two weeks after treatment. M 62 1 days
iv
11/7/2014
 1  Severe nausea & vomiting bug or flu From reading other posts I guess I took it too late. It did nothing. It's been seven hours and I'm miserable. F 42 1 days
80mg
5/28/2014
 1  Nausea Jaw pain, arm numbness, lightheaded Major Anxiety!!! F 36 2 days
4MG
2/19/2012
 1  Nausea from pain med in E.R. Horrible- headache, leg spasms that could not be controlled, dizziness, feeling of losing consciousness, entire body trembling, shortness of breath. Terror! Dose given I.V. in hospital. F 54 1 days
1X day
2/14/2012
 1  nausea from pain med takocardia and siezure...went to er due to pain from kidney infection...not on any other meds...nausea from pain med administered..given injection of zolfran, almost immediate twitching, burning in head, seizures and takocardia...ended up admitted in telemetry for almost a week!Told seizure is a possible side effect F 22 1 days
injection 1X day
10/2/2010
 1  Severe morning sickness no side effects I suppose I'm one of the only women out there where this drug didn't TOUCH my morning sickness. Not a bit. Might as well have been taking a placebo pill. Tried for about a week with no avail - I was SO disapointed! F 33 7 days
5/23/2008
 1  Gastroparesis Nervousness, Panic attacks Too pricey and did not help F 42 1 months
11/27/2007
 2  Nausea Panic attack, tingling in arms. It helps with nausea, but def not worth it. F 27 2 days
4mg 1X AN
11/4/2020
 2  Nausea from medication Headache, dizziness, rapid heartbeat, sweating, chills, numbness in fingers and lips, blurry vision Works great for nausea, but the side effects aren't worth taking this medicine F 55 30 days
4
6/20/2020
 2  Nausea For months I've been taking this both in the hospital and at home. Could never understand why my Christ hurt and my blood pressure and pulse would go up until I read the side effects. I've thrown up while on it so what's the point? F 43 6 months
7/20/2016
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 2  HG pregnancy Initially after a day I felt great and was able to eat. After 4 days of taking Zofran I woke up and thought I was having a heart attack. It was like a sumo wrestler sat on my chest compacting it, and like someone karate kicked my back between my shoulders. Very frightening. Get side effects checked out!!! F 32 1 days
4mg
12/8/2014
 2  nausea due to stomach virus4 dizziness, skin tingling stomach pain, light headed, disoriented, muscle contractions, tremors I have taken the SL in past with no problems. Felt that this was truly a great drug. When it works it is fantastic. I am not sure what happen this time. It was the oral tablets and not the sublingual and I am not sure if that makes a difference. F 52 2 days
4 mg 3X day
11/16/2010
 2  hyperemesis headache, constipation this doesn't seem to be working at all. maybe it helped the first two days but now, nothing. F 29 3 weeks
4-8mg 4X day
3/20/2010
 3  Nausea associated with pregnancy Extreme constipation, slight tiredness F 28 7 months
4mg dissol
10/3/2016
 3  Nauseau If I take this early enough it takes the edge of nausea but does not eliminate it by any stretch of the imagination. Phenergan is so superior, but doctors are more reluctant to prescribe. F 58
8 mg 2X day
6/27/2015
 3  nausea For the last few days days my poop has been white! I have scoured the internet about possible reasons, and when researching what is in these tablets, there is hydrochloride, so it might be a culprit. As for the way it worked, it worked wonderfully to relieve the nausea. F 18 1 days
1X AN
4/23/2013
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 3  morning sickness/nauseau Bad Headache, body tingled some, tremors/shaking,panic attack It made my nauseau better, but i still felt nauseus. At least i didnt throw up. But I didnt like the feeling this pill gave me. Doc told me to take 1/2 of a pill or 1 pill 8 mg. I took 1/2 once. i wont be taking it again.. did not like the after effects of the pill. ill go back to phenergan and stay tired F 37 1 days
4 1X day
9/9/2012
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 3  "morning" sickness severe insomnia Note on the dosage: the prescription was to take a 4mg tablet every 8 hours or as needed. I generally only took it once per day, occasionally twice, and once or twice I took it three times in a day. It worked wonderfully for my severe morning sickness- I felt 100% better! Unfortunately, I finally figured out that it was the cause of SEVERE INSOMNIA for me. I was getting 0-2 hours of sleep per night. Doc gave me Ambien and I STILL didn't sleep. I did some research and found it is selective antagonist of the serotonin receptor subtype, 5-HT3, and decided to see what would happen if I stopped taking it. The first 3 days off Zofran nothing happened. After that, each day I slept about 1 hour more, but I was more and more ill. At the 6 day mark, I was severely ill all over again. I switched to phenergan and hope it will be good enough that I am not throwing up and that it does not cause the severe insomnia. I have seen no other reports of such insomnia caused by Zofran, and expect I am an unfortunate and unique case. F 31 42 days
4mg 3X day
11/1/2010
  

ZOFRAN ODT  (ONDANSETRON):  This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. Ondansetron works by blocking one of the body's natural substances (serotonin) that causes vomiting.   FDA Approval Date: 1999-01-27 (Sources: U.S. Centers for Medicare Services, FDA)

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