ZOFRAN ODT Reviews (ONDANSETRON)

Average Rating: 3.7 (74 Ratings)

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 GASTROINTESTINAL, MISCELLANEOUS

 Type: Rx Drug

  

ZOFRAN ODT  (ONDANSETRON):  This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. Ondansetron works by blocking one of the body's natural substances (serotonin) that causes vomiting.   FDA Approval Date: 1999-01-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ZOFRAN ODT: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ZOFRAN ODTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Migraine cyclic vomiting I get akathesia when I take compazine, reglan and phenergan. This relieves the vomiting that occurs every 20-30 minutes. I only have these episodes 1-3 times a year but this prevents me from going into the ER. F 33 4 years
4mg
3/15/2014
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 5  nausea and emetophobia none I LOVE Zofran ODT. I have debilitating emetophobia (fear of vomitting) and a very sensitive stomach on top of that -- my doctor prescribed Zofran for me and it has really given me back my life. I take 8mg PRN ... works in as little as 10 minutes for me. F 21 2 years
12/10/2006
 5  nausea from migraine None Miracle drug for nausea and vomiting! I take 2 8mg. Works fast. Taste is minty and light, dissolves quickly for brand name. For generic taste is minty, but a little grainy, and takes longer to dissolve. Generic works just the same and cost less so I still get it. I prefer it very much over the older stanby for migraine nausea - phenergan. Made me sleep way too long. Can't say enought good things about it! HIGHLY RECOMMENDED for people with migraines who can't keep anything down. This will let you finally be able to take your pills. F 31 1.5 years
8/22/2007
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 5  Chronic nausea, reflux Lingering headache, intestinal cramps, foggy feeling Side effects were worth how much better stomach felt after taking F 31 1 years
4
4/30/2012
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 5  SEVERE NAUSEA & INTESTINAL YUCK THIS STUFF IS GREAT! I SET MY ALARM TO TAKE MY OND4, SNOOZE FOR 20, TAKE MY OTHER PILLS AND ASSURE ABSORBTION, WITHOUT WORRY OF REGURGITATION....'SHUDDERING!!!'...YOU CAN TRUST THIS STUFF! 5 STAR RATING, I NO LONGER GREET THE MORNING PORCELAIN GODDESS FACE FIRST, THANK GOODNESS!!! PUBLIC AID WILL PAY FOR IT, BUT ONLY IN 5 DAY INCREMENTS. IT'S WELL WORTH THE WEEKLY TRIP TO YOUR DRUG DEALER, UH...PHARMACIST I MEANT...TEEHEEHEE...GOOD STUFF!!! * * * * * +++ F 43 1 years
10/19/2007
 4  gastroparesis Constipation, and sometimes headaches Zofran helped me live a semi-normal life. No gastroparesis medications worked for me, and I was (and am, without zofran) constantly nauseous. zofran is the closest thing to a miracle drug, if you're okay with being backed up more than a Bangladesh roadway F 21 1 years
4mg 2X day
9/8/2023
 4  pregnancy none. I found myself "sick" with pregnancy. I was 3 months along, dropped from 120 lbs. to about 105 lbs. and keeping down about three meals a week. That's when my Dr. told me to try ZOFRAN. I took ZOFRAN every day after that...through four pregnancies. With every baby I noticed that the ZOFRAN didn't help as much. Finally with my last child, at only two and a half months along, I was in the hospital fully dosed on ZOFRAN and a couple of other similar drugs... still throwing up every hour. After a week in the hospital, my Dr. (had been frantically searching for "something" to help) rushed in and with the help of a nurse, gave me a dose of steroids. Yes, steroids. It isn't something to take lightly and it was quite literally a LAST resort. HOWEVER! It WORKED! I stepped down off the ZOFRAN pump and managed with one ZOFRAN pill in the morning and a tiny bit of a steroid pill did the trick. I was careful to take just as much as I needed to feel "ok" not "great& F 30 33 months
1/9/2009
 5  Brain Aneurysm burst Slight increase in headache on occasion. Other than that experienced no side effects. This is the best anti-nausea medication on the market today! Due to my aneurysm all I have to do is turn my head, stand up, smell food or anything and I get extremely ill. If I vomit I end up in the hospital. I now take Zofran ODT for the nausea; within a couple minutes it is gone. No more hospitalization. Unfortunately my health care provider is no longer going to carry the ODT and I will have to use the swallow. Now I will have to wait for it to work like the Phenergan which does not, compazine which does not. This is a great medication. F 44 16 months
12/2/2007
 5  Morning Sickness WONDER DRUG!!!!!!!! This was soo GREAT. I am SERVER Morning Sickness and this fixed it all. You dont need water to take it. It cost at least $25 a pill, but its sooooo worth it! ROCK GSK! GREAT!!!! F 20 10 months
9/2/2005
 5  Hyperemesis Gravidarum Severe constipation, headaches, fatigue Very expensive drug; insurance companies would rather pay for hospital stay than 9 1/2 months of this medication; best drug (IMO) for pregnant women suffering from Hyperemesis Gravidarum F 33 9 months
12/23/2007
 3  severe all day "morning" sickness drowsiness...but could be from pregnancy as well. During my first two pregnancies, I had very severe morning sickness. I was in the hospital multiple times for it. Zofran worked, but my doctor's had to make sure I actually did need it before prescribing it. With my 3rd pregnancy, it does not seem to be working at all. I would love to know, if my body may have become immune to it. F 25 9 months
8 mg 2X day
4/9/2010
 5  Hyperemesis Gravidarum moderate constipation, headache I took this medication for Hyperemesis Gravidarum. I took it in ODT form and via IV. Both forms worked very well. I need to mention that it did not completely relieve the nausea, but it did control the vomiting. I would highly recommend this medication for anyone suffering from severe nausea +/- vomiting. F 34 8 months
3/4/2009
 5  Gastroparesis Constipation. However so worth it. Often have to take 8 mg, but if taken at beginning of nausea, then that 8 mg lasts all day. Worth every penny. Pheregan works better for nausea, but I can not function at work on even a small dose of phenegan. F 53 8 months
4
12/27/2013
 3  Nausea associated with pregnancy Extreme constipation, slight tiredness F 28 7 months
4mg dissol
10/3/2016
 5  severe morning sickness all day occasional headaches This is a miracle pill! For the first 2 weeks of my pregnancy i could not move from the bed with the trash can beside it. I had tried phennergan but that didn't touch the nausea. My OB prescribed me Zofran ODT and after getting it in my system for about 2 days I could work and eat just as normal as before the pregnancy. I am now 8 months pregnant and if I skip the dosing for one day I am back to the same way i was before I started. I would definately reccomend this to anyone with severe nausea. F 21 6 months
4mg 2X day
5/2/2010
 4  Morning sickness none It did help a little. I still felt like throwing up all day, but it just helped me not throw up as much. It was nice it dissolves on your tongue so I didn't gag it back up. F 27 6 months
1/4/2007
 2  Nausea For months I've been taking this both in the hospital and at home. Could never understand why my Christ hurt and my blood pressure and pulse would go up until I read the side effects. I've thrown up while on it so what's the point? F 43 6 months
7/20/2016
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 4  hyperemesis Headache, constipation This is my third pregnancy to require Zofran. The first two times it was like a miracle cure with a minor side effect of headaches. This time I am on the generic. I don't know if if it has to do with anything, but this time it it working as well. I still throw up sometimes and feel nauseous all day and the headaches are severe. F 29 5 months
4mg 2X day
4/22/2010
 5  Morning Sickness Constipation I tried phenergen and diclegis before zofran...finally feel like I'm not a drunken sailor. Morning sickness lasted well into second trimester and zofran allowed me to still function at work, eat, and drive. I didn't throw up while taking it and it drastically reduced the constant nausea. I had initial concerns about taking while pregnant, but looked over the research and can't find any conclusive study (as the case with most medications and pregnancy) to outweigh the risk to benefit. F 31 4 months
8mg 1X day
4/2/2015
 4  Indigestion and Chronic nausea Headache (but this only happened on the first few times I took it) and drowsiness It doesn't completely knock out the nausea, but it definitely takes the edge off. It does cause some drowsiness, but nowhere near the level that phenergan causes. Phenergan used to make it very difficult for me to wake up, but this doesn't give me a problem with waking. M 23 3 months
8 mg 1X AN
4/3/2011
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ZOFRAN ODT  (ONDANSETRON):  This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. Ondansetron works by blocking one of the body's natural substances (serotonin) that causes vomiting.   FDA Approval Date: 1999-01-27 (Sources: U.S. Centers for Medicare Services, FDA)

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